Index of All Available News Articles

ACKC Secures $10 Million for Kidney Cancer Research

Long-Term Risk of Breast Cancer Recurrence After 5 Years of Endocrine Therapy

Constructing a Risk Stratification Model for Pediatric Acute Lymphoblastic Leukemia

Seattle Children’s Opens Trial for Children and Young Adults With Leukemia That Targets CD22 and CD19 Proteins Simultaneously

ESMO Asia 2017: FLAURA Trial: Osimertinib Improves Progression-Free Survival in Asian Patients With EGFR-Mutated NSCLC

ESMO Asia 2017: AXEPT Trial: New Second-Line Therapy for Metastatic Colorectal Cancer Is Effective and Safe

Patient-Reported Outcomes With Immunotherapy vs Chemotherapy in Advanced NSCLC

Antidepressant for Aromatase Inhibitor–Associated Arthralgia in Early-Stage Breast Cancer

Predictors of Cervical Precancer Treatment Failure

ESMO Asia 2017: Analysis of Mutations in Cerebrospinal Fluid in Lung Cancer With Brain Metastases

Adding Antibody-Drug Conjugate to First-Line Treatment of Advanced Classical Hodgkin Lymphoma

Mismatch Repair–Deficiency Testing in Patients With Colorectal Cancer

5-Year Outcomes With Extended Adjuvant Therapy in HER2-Positive Breast Cancer

ESMO Asia 2017: Alectinib More Effective Than Crizotinib in Asian Patients With ALK-Positive NSCLC

Predictive Model for Ischemic Heart Disease and Stroke in Childhood Cancer Survivors

FDA Approves Obinutuzumab for Previously Untreated Advanced Follicular Lymphoma

FDA Announces Comprehensive Regenerative Medicine Policy Framework

Differences in Insurance Coverage Associated With Nearly Half of Black-White Survival Disparity in Colorectal Cancer

Are African American Women With Type 2 Diabetes at Increased Risk for ER-Negative Breast Cancer?

FDA Expands Approval of Sunitinib Malate for Adjuvant Treatment of Renal Cell Carcinoma After Nephrectomy

ESMO Publishes Precision Medicine Glossary

Hospital Groups File Lawsuit to Stop Significant Payment Cuts for 340B Hospitals

ASCO Endorses ASTRO Guideline on Stereotactic Body Radiotherapy for Early-Stage NSCLC

Representation of Minorities and Women in Oncology Clinical Trials From 2003 to 2016

Comparison of First-Line Treatments in Chronic Myeloid Leukemia

FDA Approves Fulvestrant in Combination With Abemaciclib in Hormone Receptor–Positive, HER2-Negative Advanced Breast Cancer

FDA Authorizes MSK-IMPACT Tumor Profiling Assay

Ventana MMR IHC Panel for Patients Diagnosed With Colorectal Cancer Receives FDA Clearance

Adding Targeted Agent to Chemotherapy in Second-Line Treatment of Advanced Gastric Cancer

Long-Term Results of First-Line Regimens in Advanced Symptomatic Follicular Lymphoma

Study Finds HPV Screening May Be More Sensitive Than Pap Test for Detecting Cervical Cancer

TMPRSS2-ERG Genetic Fusion May Be Associated With Low-Risk Prostate Cancer

Chronic Stress Hormones May Promote Resistance to EGFR Inhibitors in Patients With Lung Cancer

Novel Psychosocial Intervention for Fear of Cancer Recurrence

Survival as Quality Metric in Cancer Care

Immunotherapy in PD-L1–Positive Advanced Cervical Cancer

Donald Coffey, PhD, Prostate Cancer Expert, Dies at 85

FDA Grants Regular Approval of Dasatinib for Pediatric Philadelphia Chromosome–Positive CML in Chronic Phase

Association of Event-Free Survival at 24 Months With Overall Survival in Peripheral T-Cell Lymphoma

Combination Therapy for Advanced Lung and Thymus Carcinoids

FDA Approves Brentuximab Vedotin for Primary Cutaneous Anaplastic Large Cell Lymphoma

FDA Approves Letermovir for Prophylaxis of Cytomegalovirus Infection and Disease in Allogeneic Stem Cell Transplant Patients

Fat Cells May Inactivate Chemotherapeutic Drug and Contribute to Poorer Survival in ALL

Higher Risk of Breast Cancer Does Not Motivate Cancer Screening in Many Women

Internal Radiotherapy vs Kinase Inhibitor in Advanced Hepatocellular Carcinoma

Predictors of Posthospital Care Transitions in Advanced Cancer

Association of Tumor HER3 Expression With Treatment Outcome in Advanced Colorectal Cancer

ASCO Cites Evidence That Alcohol Is Linked to Cancer, Calls for Reduced Alcohol Consumption

Hospital Emergency Department Practices for Treating Older Adults With Cancer

Long-Term Follow-up of Cardiac Function After Adjuvant Therapy With Trastuzumab in Early Breast Cancer

Characteristics of Recurrence in Stage I to III Midgut Neuroendocrine Tumors

HSD3B1 Variant and Response to Nonsteroidal CYP17A1 Inhibition in Castration-Resistant Prostate Cancer

FDA Approves Alectinib for ALK-Positive Metastatic NSCLC

FDA Approves Vemurafenib for Certain Patients With Erdheim-Chester Disease

FDA Accepts sBLA for Bevacizumab as a Front-Line Treatment for Advanced Ovarian Cancer

Combination Therapy for Advanced BRAF V600–Mutant Anaplastic Thyroid Cancer

Novel Adverse Genomic Rearrangement Signature in High-Grade Serous Ovarian Cancer

Worldwide Cancer Incidence and Mortality Among Persons Aged 20 to 39 in 2012

Factors Associated With Outcome in Pediatric Adrenocortical Tumors

MicroRNA Expression–Based Risk Model for Pediatric Acute Myeloid Leukemia

Novel Tyrosine Kinase Inhibitor for ALK- or ROS1-Rearranged NSCLC

CHEST 2017: American College of Chest Physicians Unveils New Lung Cancer Screening Guidelines

CHEST 2017: Gender, Language, and Treatment Setting as Barriers in Screening and Patient Care in Lung Cancer

Changes in Uninsured Status Among Nonelderly Cancer Patients Under the Affordable Care Act

ASCO Endorses ASTRO Guideline on Radiation Therapy for Oropharyngeal Squamous Cell Carcinoma

Results From Phase III ARROW Study of Once-Weekly Carfilzomib in Relapsed/Refractory Multiple Myeloma

Adjuvant Dabrafenib/Trametinib Combination Granted FDA Breakthrough Therapy Designation for Stage III Melanoma With BRAF V600 Mutation

The Liver Meeting: Daily Aspirin May Reduce Risk for Hepatitis B Virus–Related Liver Cancer

The Liver Meeting: Direct-Acting Antiviral Medications as Hepatitis C Treatment May Reduce Risk of Liver Cancer

Complications and Patient Satisfaction After Breast Reconstruction in Women Receiving Radiotherapy

PanCan Risk Model for Lung Cancer Screening

New Persistent Opioid Use After Curative-Intent Cancer Surgery

Long-Term Survivors of Childhood Cancer Prone to ‘Job Lock’ due to Worries About Losing Health Insurance

Final Results of German Trial of PET-Guided Treatment in Advanced Hodgkin Lymphoma

HSD3B1 Genotype and Outcomes With ADT After Radiotherapy for Localized Prostate Cancer

ASCO/CCO Focused Guideline Update on Role of Bone-Modifying Agents in Metastatic Breast Cancer

ASHG 2017: Quantifying Breast Cancer Risk Based on Rare Variants and Background Risk

AACR-NCI-EORTC: Rising Number of Seamless Clinical Trials in Oncology

AACR-NCI-EORTC: NCI-MATCH Reaches Central Patient-Screening Goal

FDA Approves New Treatment for Adults With Mantle Cell Lymphoma

AACR-NCI-EORTC: Noninvasive Computational Imaging Approach May Help Predict Response to Immunotherapy

AACR-NCI-EORTC: Colorectal Cancer Test Could Detect Early Cancer-Causing Genetic Biomarkers With High Degree of Sensitivity

CD8-Positive Tumor-Infiltrating Lymphocytes and Survival in High-Grade Serous Ovarian Cancer

Racial/Ethnic Disparities in Cancer-Specific Survival in California

Gary Gilliland, MD, PhD, Testifies Before Congress on NIH Funding System

AACR-NCI-EORTC: Tipifarnib Shows Durable Antitumor Activity in HRAS-Mutant Head and Neck Cancer

AACR-NCI-EORTC: Tazemetostat as Treatment for Certain Pediatric Relapsed or Refractory Solid Tumors

FDA Approves Axicabtagene Ciloleucel for Large B-Cell Lymphoma

AACR-NCI-EORTC: Colorectal Cancers May Mutate to Escape Immune System Detection

AACR-NCI-EORTC: Gene Therapy Shows Early Efficacy Against Recurrent Brain Cancer

2-Year Survival Outcomes With Immunotherapy in Advanced NSCLC

New Biosimilar Educational Materials for Health-Care Professionals From the FDA

FDA Accepts sBLA for Nivolumab in Resected, High-Risk, Advanced Melanoma

Early Study Suggests Potential Role of Paclitaxel in Peripheral Neuropathy and Possible Preventive Measures

Potential Risk Activities and Breast Cancer–Related Lymphedema in Patients Undergoing Bilateral Surgery

Combination Therapy for Docetaxel-Pretreated Metastatic Castration-Resistant Prostate Cancer

CELESTIAL Trial: Cabozantinib Meets Primary Endpoint of Overall Survival in Patients With Advanced Hepatocellular Carcinoma

FDA Approves Intravenous Rolapitant for Delayed Chemotherapy-Induced Nausea and Vomiting

Potential Treatment of Chordoma With PI3K Inhibitors

Extended Aromatase Inhibitor Therapy After Sequential Endocrine Therapy

Anti–T-Lymphocyte Globulin and Chronic GVHD-Free Survival in Unrelated Myeloablative HCT

Changes in Opioid Prescription for Cancer Patients Referred to Outpatient Palliative Care

2017 ASCO Palliative Care: Resilience Intervention Improves Quality of Life for Adolescents and Young Adults With Cancer

2017 ASCO Palliative Care: Patients With Advanced Cancer Prefer Oncologists Not Use Computers in the Exam Room

FDA Grants Priority Review for Olaparib in Metastatic Breast Cancer

2017 ASCO Palliative Care: Yoga Can Be an Effective Supportive Therapy for People With Lung Cancer and Their Caregivers

2017 ASCO Palliative Care: People With Leukemia and Their Oncologists Have Vastly Different Perceptions of Prognosis

Long-Term Outcomes With BRAF and MEK Inhibition in BRAF V600–Mutant Metastatic Melanoma

MAF Amplification and Outcomes With Adjuvant Zoledronic Acid in Early Breast Cancer

Effectiveness of Sentinel Lymph Node Biopsy in Patients With Newly Diagnosed Melanoma

Intratumoral Plasmid IL-12 With Electroporation in Stage III/IV Melanoma

Axl Inhibitor BGB324 in Combination With Trametinib Plus Dabrafenib or Pembrolizumab in Advanced Melanoma

FDA Accepts sBLA for Durvalumab in Locally Advanced Unresectable NSCLC

Predicting Risk of Subsequent CNS Tumors in Survivors of Childhood Cancer

Enhancer of Zeste Homolog 2 Expression and Prognosis in Localized Renal Cell Carcinoma

IASLC 2017: Exercise Interventions in Advanced Lung Cancer Patients Led to Increased Functionality

IASLC 2017: Community Engagement Interventions May Reduce Disparities in Lung Cancer Outcomes Among Minorities

IASLC 2017: Non–Small Cell Lung Cancer Survival Rates Higher Among Patients Treated at Academic Centers

IASLC 2017: Poziotinib Yields High Response Rates in Patients With NSCLC With EGFR Exon 20 Insertion

Survival in Patients Treated With Adjuvant Chemoradiotherapy After Resection of Gastric Cancer

Sperm Banking for Adolescent Males With Newly Diagnosed Cancer

IASLC 2017: First-Line Pembrolizumab Increases Overall Survival vs Chemotherapy in Metastatic NSCLC With High Levels of PD-L1

FDA Approves CAR T-Cell Therapy to Treat Adults With Certain Types of Large B-Cell Lymphoma

IASLC 2017: IASLC Releases New Atlas of EGFR Testing

IASLC 2017: Treatment Based on BRCA1 Level Does Not Increase Survival of Stage II/III NSCLC Node-Positive Resected Patients

IASLC 2017: Biopsy Specimen Found to Be Reliable for Evaluating DLL3 Expression in Small Cell Lung Cancer

Combination Therapy for Patients With Advanced Unresectable Melanoma

Immunotherapy for Advanced Soft-Tissue and Bone Sarcoma

Norman E. Sharpless, MD, Sworn in as Director of the National Cancer Institute

IASLC 2017: REVEL Trial Subgroup Analysis Further Clarifies Outcomes With Ramucirumab Plus Docetaxel in Advanced Non–Small Cell Lung Cancer

IASLC 2017: Research Confirms IASLC Characterization of Uncertain R Status With Prognosis Between R0 and R1

PI3K Inhibition in Relapsed or Refractory Indolent Lymphoma

Outcomes in Patients With Metastatic Lung Cancer Receiving PD-1/PD-L1 Inhibitors With Thoracic Radiotherapy

IASLC 2017: Integration of Smoking Cessation With CT Lung Cancer Screenings

IASLC 2017: Race, Socioeconomic Factors Are Influential in NSCLC Survival Rates

IASLC 2017: Lorlatinib in ALK-Positive and ROS1-Positive Advanced Non–Small Cell Lung Cancer

IASLC 2017: CheckMate-032: Nivolumab Alone or With Ipilimumab in Recurrent SCLC With High Tumor Mutation Burden

FDA Grants Priority Review for Cabozantinib in Previously Untreated Advanced Renal Cell Carcinoma

Immunotherapy for Previously Treated Advanced Gastric Cancer

Long-Term Use of Long-Acting Insulin Analogs and Breast Cancer Risk in Type 2 Diabetes

IASLC 2017: Early Palliative Care Provides No Quality-of-Life Benefits for Patients With Recently Diagnosed Malignant Pleural Mesothelioma

IASLC 2017: Brigatinib in ALK-Positive Non–Small Cell Lung Cancer

IASLC 2017: Combination of Lurbinectedin and Doxorubicin in Relapsed Small Cell Lung Cancer

Maintenance Therapy After ASCT in Younger Patients With Mantle Cell Lymphoma

Single-Center Study of Adjuvant Beta-Blocker Therapy for Cutaneous Melanoma

Amended Health Insurance Rule Threatens Key Component of Standard Cancer Treatment

FDA Clears 7T Magnetic Resonance Imaging Device

FDA Grants Priority Review for Abemaciclib as Initial Treatment of Advanced Breast Cancer

Addition of EGFR Tyrosine Kinase Inhibitor to Chemotherapy in Resistant Non–Small Cell Lung Cancer

Potential Biomarkers to Identify Patients at Risk for Neurotoxicity From CAR T-Cell Therapy

sNDA Submitted for Rucaparib as Maintenace Treatment for Patients With Platinum-Sensitive Recurrent Ovarian Cancer

Results From the Phase III JUNIPER Trial Evaluating Abemaciclib in KRAS-Mutated, Advanced NSCLC

Role of the E7 Gene in High-Risk HPV

Cryotherapy for Preventing Chemotherapy-Induced Peripheral Neuropathy in Patients With Breast Cancer

First-Line Immunotherapy for Cisplatin-Ineligible Patients With Advanced Urothelial Cancer

Incidence of Endocrine Dysfunction With Immune Checkpoint Inhibitors

Osimertinib Granted Breakthrough Therapy Designation for First-Line Treatment of EGFR Mutation–Positive NSCLC

Relationship Between Targeted HER2 Therapy and Breast Reconstruction

Initial Treatment With CDK4/6 Inhibitor and Aromatase Inhibitor for Advanced Breast Cancer

Baseline Cardiovascular and Heart Failure Risks in Non-Hodgkin Lymphoma Survivors

Adjuvant Chemotherapy vs Observation After Preoperative Chemoradiotherapy and Resection in Gastroesophageal Cancer

Cancers Associated With Overweight and Obesity Make Up 40% of Cancers Diagnosed in the United States

Immune-Related Adverse Events and Outcomes With Immunotherapy for NSCLC

Comorbidity and Prostate Cancer–Specific and Other-Cause Mortality

Brentuximab Vedotin Granted FDA Breakthrough Therapy Designation in Front-Line Advanced Hodgkin Lymphoma

Integrative Therapies in Palliative Care Project

Ontario Province–Wide Symptom Screening and Opioid Prescribing Rates in Older Patients With Cancer

FDA Accepts sNDA for Lenvatinib for the Treatment of Hepatocellular Carcinoma

Momelotinib vs Ruxolitinib in Janus Kinase Inhibitor–Naive Myelofibrosis

Study Finds 'Standard Care' Treatments in Breast Cancer Clinical Trials Not Always Standard

European Commission Approves Obinutuzumab for Previously Untreated Advanced Follicular Lymphoma

What Is the Most Important Factor Women Consider in Deciding on SERM Use to Reduce Their Risk of Breast Cancer?

Comparison of First-Line Treatments for EGFR-Mutant NSCLC

Inpatient Palliative Care During HCT and Psychological Distress After Transplantation

Lymphoma Physician-Scientist Oliver Press, MD, PhD, Dies at 65

FDA Conducts Global Operation to Protect Consumers From Potentially Dangerous Prescription Drugs Sold Online

FDA Grants Priority Review for Pertuzumab for Adjuvant Treatment of HER2-Positive Early Breast Cancer

Study Finds Liquid Biopsy May Provide Predictive Biomarkers for Checkpoint Inhibitor Response

10-Year Survival With vs Without Axillary Dissection in Invasive Breast Cancer With Sentinel-Node Metastasis

Consolidative Radiotherapy for Limited Metastatic NSCLC

Molecular Profiling of Key Survival Proteins in B-Cell Lymphoma Subtypes

Nivolumab Approved in Japan for Unresectable Advanced or Recurrent Gastric Cancer That Has Progressed After Chemotherapy

Addition of MET Inhibitor to First-Line Chemotherapy in Advanced Gastric Cancer

Pooled Analysis Safety Profile of Combination Immunotherapy for Advanced Melanoma

ASTRO 2017: Shorter Course of Radiation Treatment Safe for Breast Cancer Patients Under 50

ASTRO 2017: Uninsured Patients With Cancer Saw Increased Coverage for Care Following Medicaid Expansion

ASTRO 2017: Accelerated Breast Radiation Therapy Following Mastectomy Can Shorten Treatment Time While Maintaining Tumor Control

Combination Therapy for Previously Untreated BRAF V600E–Mutant Metastatic NSCLC

Changes in Insurance Coverage and Diagnosis Stage After Affordable Care Act Implementation

Preexisting Mental Illness and All-Cause and Breast Cancer Mortality in Elderly Breast Cancer Patients

ASTRO 2017: Patients With Breast Cancer Find Radiation Therapy Experience Better Than Expected

ASTRO 2017: GOG-249 Confirms Adjuvant Pelvic Radiation as Standard of Care for High-Risk, Early-Stage Endometrial Cancer

ASTRO 2017: Aggressively Reduced Radiation Therapy May Benefit Some Patients With HPV-Related Throat Cancer

Study Finds Smoking Negatively Impacts Long-Term Survival After Breast Cancer

Adjuvant Therapy for Localized or Locally Advanced Renal Cell Carcinoma

Second Annual ASCO Advocacy Summit Convenes in Washington, DC

ASTRO 2017: Immune Response May Be Prognostic for Prostate Cancer Survival, Recurrence, and Response to Radiation Therapy

ASTRO 2017: RTOG 0617: Long-Term Survival Rates Improve Previous Estimates for Locally Advanced Lung Cancer

Tumor-Infiltrating Lymphocytes in African Americans and European Americans With Triple-Negative Breast Cancer

Cumulative Burden of Chronic Health Conditions in Childhood Cancer Survivors

MicroRNA-Loaded Minicells in Recurrent Malignant Pleural Mesothelioma

ASTRO 2017: Radiation-Immunotherapy Combination May Benefit Some Patients With Late-Stage Cancer

ASTRO 2017: Distress in Patients Receiving Radiation Associated With Missed Appointments, Hospitalization

ASTRO 2017: Adding Radiation to Maintenance Chemotherapy May Benefit Patients With Limited Metastatic NSCLC

Religiously Tailored Educational Intervention to Encourage Mammography in American Muslim Women

Adjuvant Dabrafenib and Trametinib in Resected Stage III BRAF-Mutated Melanoma

Addition of Motesanib to Paclitaxel/Carboplatin in East Asian Patients With Advanced NSCLC

ASTRO 2017: Biomarker Blood Test Predicts Survival Following Localized Lung Cancer Treatment

ASTRO 2017: IAEA Trial: Safety, Efficacy of High-Dose Brachytherapy Plus Pelvic Radiation for Cervical Cancer

ASTRO 2017: Urban Cancer Center Finds 75% of Its Patients With Depression Were Previously Undiagnosed

FDA Grants Accelerated Approval to Pembrolizumab for Advanced Gastric Cancer

FDA Grants Accelerated Approval to Nivolumab for Hepatocellular Carcinoma Previously Treated With Sorafenib

Olaparib Receives Positive pCODR Recommendation for Treatment of BRCA-Mutated Ovarian Cancer

Durvalumab Consolidation After Chemoradiotherapy in Stage III NSCLC

Adjuvant Nivolumab vs Ipilimumab in Resected Stage III or IV Melanoma

Preexisting Dementia and Survival in Older Patients With Stage III Colon Cancer

Tibetan Yoga Practice May Improve Sleep Quality for Patients With Breast Cancer Undergoing Chemotherapy

Positive Results from Phase III MURANO Trial Evaluating Venetoclax in Combination With Rituximab in Relapsed/Refractory CLL

Overall Survival With Nivolumab/Ipilimumab, or Nivolumab Alone, vs Ipilimumab in Advanced Melanoma

Surgeon-Initiated Gene-Expression Profile Testing in Early-Stage Breast Cancer and Time to Start of Chemotherapy

Assessing and Managing CAR T-Cell Treatment Toxicities

AACR Releases 2017 Cancer Progress Report: Harnessing Research Discoveries to Save Lives

Combination of Inotuzumab Ozogamicin and Low-Intensity Chemotherapy in Relapsed or Refractory Ph-Negative ALL

Final Efficacy Analysis of 9-Valent Human Papillomavirus Vaccine Trial

New ASCO Guideline Aims to Improve Clinician Communication With Patients

First-Line Gemcitabine/Docetaxel vs Doxorubicin in Advanced Soft-Tissue Sarcoma

Addition of Bortezomib to R-CHOP in Non–Germinal Center B-Cell–Like Lymphoma

Does Reducing the Starting Dose of Sorafenib Affect Outcomes in Hepatocellular Carcinoma?

Peter W.T. Pisters, MD, MHCM, Named Sole Finalist in Search for President, MD Anderson

Whole-Genome Sequencing Reveals Breast Cancers With Mismatch-Repair Deficiencies

ESMO 2017: KEYNOTE-045: Updated Results Support Pembrolizumab as Second-Line Treatment in Advanced Urothelial Cancer

Adjuvant Chemotherapy vs Observation After Neoadjuvant Therapy and Radical Cystectomy for Bladder Cancer

ESMO 2017: 'Triggers': A New Tool to Assess Patients’ Palliative Needs

ESMO 2017: Abdominal to Peripheral Fat Ratio May Predict Risk of Cancer Diagnosis in Postmenopausal Women

ESMO 2017: KEYNOTE-040 Evaluates Pembrolizumab in Head and Neck Cancer

ESMO 2017: MONARCH 3: Abemaciclib as Initial Therapy Improves Outcome in Endocrine-Sensitive Advanced Breast Cancer

ESMO 2017: Patients Struggle With Key Aspects of Clinical Trial Methodology

ESMO 2017: NOR-CAYACS Trial: Factors That May Limit Work Ability of Young Adult Cancer Survivors

NCCN Guidelines to Include Categories of Preference

Osimertinib in First-Line Treatment of EGFR Mutation–Positive Advanced NSCLC

Recombinant Adenovirus Interferon-α With Syn3 in BCG-Refractory or Relapsed Non–Muscle Invasive Bladder Cancer

FDA Approves Copanlisib for Adults With Relapsed Follicular Lymphoma

FDA Approves First Biosimilar for the Treatment of Cancer

ESMO 2017: PACIFIC Trial: Durvalumab Improves Progression-Free Survival in Stage III Lung Cancer

ESMO 2017: Pembrolizumab Shows Promising Response Rate in Pretreated Metastatic Gastric Cancer

ESMO 2017: Patients May Feel Psychosocial Impact of Chemotherapy More Acutely Than Physical Side Effects

ESMO 2017: Study Confirms Chemoradiation Is Best Treatment for Locally Advanced Cervical Cancer

Eribulin vs Dacarbazine in Advanced Liposarcoma Subgroup

Posttransplantation Cyclophosphamide-Based Haploidentical HCT in Hodgkin Lymphoma

Hospitalization and Rehospitalization After Diagnosis of Advanced Cancer

ESMO 2017: Adding Taselisib to Neoadjuvant Letrozole Improves Outcomes in Early Breast Cancer

ESMO 2017: New Data Confirms Superiority of Docetaxel-Based Triplet Therapy in Esophagogastric Cancer

ESMO 2017: ALEX and ALUR Trials: Alectinib Shows CNS Benefit in ALK-Positive NSCLC

ESMO 2017: DNA Sequencing Could Open Up New Drug Indications for Patients With Rare Cancers

ESMO 2017: ICON8 Trial Reaffirms Standard Chemotherapy Dosing in Ovarian Cancer

ESMO 2017: Patients With High-Risk Prostate Cancer May Benefit From Addition of Docetaxel or Abiraterone/Prednisolone to Long-Term Hormone Therapy

First-in-Human Study of Tamoxifen Metabolite Z-Endoxifen in Endocrine-Refractory Metastatic Breast Cancer

Pembrolizumab in PD-L1–Positive Nasopharyngeal Carcinoma

Survey on Training in Geriatrics/Geriatric Oncology for Hematology-Oncology Fellows

ESMO 2017: Some Stroke Survivors May Have Underlying Cancer

ESMO 2017: MIRO Trial: 3-Year Outcomes Favor Laparoscopic Surgery for Esophageal Cancer

ESMO 2017: Rucaparib Boosts Progression-Free Survival in BRCA-Mutant Recurrent Ovarian Cancer

Adding First-Line Ipilimumab to Paclitaxel/Carboplatin in Advanced Squamous NSCLC

Alzheimer’s Disease Risk in Medicare Patients Receiving Androgen-Deprivation Therapy for Prostate Cancer

Remnant Liver Ischemia and Cancer-Specific Survival After Resection of Colorectal Liver Metastases

ESMO 2017: Combination Targeted Adjuvant Therapy Doubles Relapse-Free Survival in Stage III Melanoma

ESMO 2017: Adjuvant Nivolumab Superior to Ipilimumab in Surgically Resected Stage III/IV Melanoma

Cytoreductive Surgery With Hyperthermic Intraperitoneal Chemotherapy

Cabozantinib Salvage Therapy in Tyrosine Kinase Inhibitor–Refractory Differentiated Thyroid Cancer

ESMO 2017: Phase III IFCT-0302 Trial Assesses Minimal vs CT Scan–Based Follow-up for Completely Resected NSCLC

ESMO 2017: MINDACT Study in Early-Stage Breast Cancer Shows Even Small Tumors Can Be Aggressive

ESMO 2017: Overuse of Tumor Marker Tests in Primary and Secondary Care

Association of Supplemental Vitamin B Use and Lung Cancer in VITAL Cohort

Health-Related Quality of Life With Everolimus vs Placebo in Patients With Neuroendocrine Tumors

Study Finds Gut Microbes May Promote Immune Responses Against Colorectal Cancer

Guadecitabine in Treatment-Naive Older Patients With Acute Myeloid Leukemia

Immunologic Biomarkers and Survival in Third-Generation CAR T-Cell Therapy

Douglas R. Lowy, MD, and John T. Schiller, PhD, to Receive 2017 Lasker Award

CMS Grants Disaster Exceptions/Exemptions for Medicare-Certified Providers Affected by Hurricane Harvey

Zika Virus Shows Oncolytic Activity Against Glioblastoma Stem Cells in Preclinical Trial

Addition of EGFR-Targeting Vaccine to Temozolomide in EGFRvIII-Expressing Glioblastoma

Immune-Related Toxicity and Time to Treatment Failure With Nivolumab Plus Ipilimumab in Advanced Melanoma

Financial Burden Among Survivors of Childhood Cancer

FDA Clears Mammography Device With Option for Patient-Assisted Compression

Overall Survival With Carfilzomib vs Bortezomib in Relapsed or Refractory Multiple Myeloma

Adipose Tissue and Cancer Risk

Assessment of Embedding Palliative Care Nurse Practitioners in Oncology Clinics

FDA Approves Gemtuzumab Ozogamicin for Treatment of Acute Myeloid Leukemia

Genetic Variant May Significantly Lower Risk of Breast Cancer in Women With History of Preeclampsia

Labetuzumab Govitecan in Heavily Pretreated Patients With Metastatic Colorectal Cancer

Adding Adjuvant Erlotinib to Gemcitabine After R0 Resection of Pancreatic Cancer

FDA Statement Regarding Safety Concerns Related to Investigational Use of Pembrolizumab in Multiple Myeloma

Androgen-Deprivation Therapy May Be Associated With Higher Risk of Heart Failure in Early-Stage Prostate Cancer

Artificial Intelligence May Help With Earlier Detection of Skin Cancer

Pembrolizumab vs Ipilimumab in Advanced Melanoma: Final Overall Survival Analysis of KEYNOTE-006

Postdiagnosis Statin Use and Mortality in Prostate Cancer

Durvalumab in Locally Advanced or Metastatic Urothelial Carcinoma

ASCO Publishes Resources for Cancer Care Providers and Patients Affected by Hurricane Harvey

FDA Approves First CAR T-Cell Therapy for Pediatric and Young Adult Patients With B-Cell Precursor ALL

FDA Grants Breakthrough Therapy Designation to DS-8201 for HER2-Positive Metastatic Breast Cancer

Tivozanib Approved in the European Union for the Treatment of Advanced Renal Cell Carcinoma

Phase III ALCYONE Study of Daratumumab in Front-Line Treatment of Multiple Myeloma

Individualized Adaptive Stereotactic Body Radiotherapy for Liver Tumors

Concurrent Treatment With OX40 Agonist Antibody and PD-1 Blockade

Integration of Oncology and Palliative Care in a Solid Tumor Inpatient Service

FDA Accepts sBLA, Grants Priority Review for Obinutuzumab in Previously Untreated Follicular Lymphoma

2018 Pershing Square Sohn Cancer Research Prize Opens for Applications on October 2, 2017

FDA Approves Fulvestrant as Monotherapy for Expanded Use in Breast Cancer

Metastasis-Free Survival as Surrogate for Overall Survival in Localized Prostate Cancer

Association of Systemic Inflammation and Sarcopenia With Survival in Early-Stage Colorectal Cancer

HPV Vaccination Rates Especially Low Among Childhood Cancer Survivors

Palliative Care May Substantially Decrease Health-Care Utilization in Patients With Advanced Cancer

Medical Costs and HPV Vaccination in Oropharyngeal Cancer

Obinutuzumab vs Rituximab Plus CHOP in Previously Untreated Diffuse Large B-Cell Lymphoma

Women More Likely Than Men to Experience Response After Induction Chemoradiotherapy and Esophagogastrectomy for Esophageal Cancer

Loss of Heterozygosity in BRCA Gene May Influence Survival in Breast and Ovarian Cancers

Reduced-Dose Cabazitaxel After Docetaxel in Metastatic Castration-Resistant Prostate Cancer

Use of CD4-Positive T Cells With MHC Class II–Restricted Receptors Targeting MAGE-A3 in Metastatic Cancer

Treatment of Nonmetastatic Muscle-Invasive Bladder Cancer: AUA/ASCO/ASTRO/SUO Guideline

African American Men Have Lowest Survival Rates Among Patients With Anal Cancer

Clinical Genomics Implements QIAGEN’s Tube Collection Technology for Colorectal Cancer Recurrence Assay

Psychological Outcomes in Adolescents With a Parent Dying of Cancer

Nodal Stage Migration and Prognosis in Anal Cancer

Prolonged and Intensified Neoadjuvant Therapy for Esophageal Adenocarcinoma

Early-Phase Study Finds Vitamin C May Activate TET2 Function

Comparison of Screening Recommendations for Mammography

Screening for Occult Cancer in Patients With Unprovoked Venous Thromboembolism

Adjuvant Temozolomide in 1p/19q Non-Codeleted Anaplastic Glioma

AKT Inhibitor Ipatasertib in Metastatic Triple-Negative Breast Cancer

Liquid Biopsies Identify Distinct Genomic Profiles With Potentially Targetable Alterations in Carcinoma of Unknown Primary

Detection of Early-Stage Cancers With Circulating Tumor DNA

Arsenic Trioxide and Reduced Anthracycline Dose in Pediatric Acute Promyelocytic Leukemia

Adding First-Line Selective Internal Radiotherapy to Chemotherapy in Patients With Liver Metastases From Colorectal Cancer

CheckMate-214: Nivolumab and Ipilimumab in Intermediate- and Poor-Risk Previously Untreated Advanced or Metastatic RCC

Crizotinib in Pediatric ALK-Positive Anaplastic Large Cell Lymphoma and Inflammatory Myofibroblastic Tumors

Off-the-Shelf, Virus-Specific T Cells for Treating Viral Infections After Transplantation

FDA Approves Olaparib Tablets for Maintenance Treatment in Ovarian Cancer

FDA Approves Inotuzumab Ozogamicin for Relapsed or Refractory B-Cell Precursor ALL

FDA Accepts sBLA and Grants Priority Review for Brentuximab Vedotin in Cutaneous T-Cell Lymphoma

Plasma Epstein-Barr Virus DNA Screening for Nasopharyngeal Cancer

Association of Pretransplant Vitamin D Deficiency and Relapse in Myeloid Malignancies

End-of-Life Care for Older Patients With Acute Myeloid Leukemia

ASCO Guideline on Stage IV NSCLC Therapy Updated

Short-Term Risk of Arterial Thromboembolism in Newly Diagnosed Patients With Cancer

Effect of Azithromycin on Airflow Decline–Free Survival After Allogeneic HSCT for Hematologic Malignancy

Surveillance Mammography by Life Expectancy in Older Breast Cancer Survivors

Germline Mutations in Apparent Sporadic Pancreatic Adenocarcinoma

Clonal Hematopoiesis in Patients With Nonhematologic Cancers

Lung Cancer Clinical Trial Eligibility Criteria Increase in Number, Complexity

Partial-Breast and Reduced-Dose Radiotherapy After Breast-Conserving Surgery

Survival After In-Hospital Cardiac Arrest in Patients With Advanced Cancer

Colorectal Cancer Mortality Rates in Adults Aged 20 to 54 Years From 1970 to 2014

Out-of-Pocket Costs Remain High, Even for Insured Patients With Cancer

Imaging and Biomarker Test Could More Accurately Predict Longer-Term Patient Response to Regorafenib in Colorectal Cancer

First-Line Cabazitaxel vs Docetaxel in Metastatic Castration-Resistant Prostate Cancer

Genomic Characteristics and Immune Infiltration in Triple-Negative Breast Cancer

Final Overall Survival Results of GOG 240 Trial Adding Bevacizumab to Chemotherapy in Advanced Cervical Cancer

Increased Endometrial Cancer Rates Found in Women With Increased Levels of Cadmium

FDA to Expand Public Education Campaign to Focus on Prevention of Youth E-Cigarette Use

Effect of Radiotherapy After Breast-Conserving Surgery Among Breast Cancer Subtypes

New Device to Test for Cervical Cancer May Be Less Painful for Patients, Produce Better Results

Identifying Essential Genes for Cancer Immunotherapy

Health-Related Quality of Life With Immediate vs Delayed ADT in Prostate Cancer

Predisposition to Breast Cancer Due to Mutations Other Than BRCA1 and BRCA2 in Ashkenazi Jewish Women

Factors in Discontinuation of Palliative Radiotherapy

Higher Opioid Use Among Cancer Survivors

Senate Passes the RACE for Children Act

Bone-Targeted Therapies for Men With Prostate Cancer Receiving Androgen-Deprivation Therapy

Ovarian Function Recovery During Anastrozole Therapy in Postmenopausal Patients With Breast Cancer

Radiotherapy Fractionation for Head and Neck Cancers

Perioperative Anti-inflammatory, Antistress Drugs May Reduce Postsurgical Metastatic Disease Recurrence

Study Maps Mutation That May Drive Meningioma Development in Childhood Cancer Survivors

Fat Intake and Lung Cancer Risk

Physician Orders for Life-Sustaining Treatment Form Use and End-of-Life Quality-of-Care Metrics in Cancer Patients

Cancer at Baseline Screening in Patients With Li-Fraumeni Syndrome

Patients With Advanced Cancer Presenting to Emergency Departments With Delirium Likely to Die Earlier

Nivolumab in Advanced DNA Mismatch Repair–Deficient or Microsatellite Instability–High Colorectal Cancer

Lenalidomide Maintenance After Autologous Stem Cell Transplantation in Multiple Myeloma

FDA Approves Liposome-Encapsulated Combination of Daunorubicin-Cytarabine for Some Types of Poor-Prognosis AML

FDA Grants Alectinib Priority Review for Initial Treatment of ALK-Positive Lung Cancer

Osimertinib Improves Progression-Free Survival for EGFR-Positive NSCLC in the Phase III FLAURA Trial

FDA Announces Comprehensive Regulatory Plan to Shift Trajectory of Tobacco-Related Disease, Death

Olaparib Tablets as Maintenance in BRCA1/2-Mutant Platinum-Sensitive Relapsed Ovarian Cancer

Trastuzumab-Based Regimens in Older Women With Early Breast Cancer

Adverse Pathologic Findings in Low-Volume Intermediate-Risk Prostate Cancer

FDA Expands Ibrutinib Indications to Chronic Graft-vs-Host Disease

Launch of Watson-Powered Genomic Sequencing Service to Help Physicians Bring Precision Cancer Treatments to Patients Nationwide

10-Year Follow-up on Adjuvant Tamoxifen and Exemestane in Postmenopausal Early Breast Cancer

Comparison of Circulating Tumor DNA and Metastatic Tissue Biopsy in Identifying Mutations in Prostate Cancer

Effect of BRAF V600E Mutation on Outcome in Pediatric Low-Grade Gliomas

FDA Approves Enasidenib in Relapsed or Refractory Acute Myeloid Leukemia

FDA Grants Acalabrutinib Breakthrough Therapy Designation for the Treatment of Mantle Cell Lymphoma

FDA Approves Nivolumab in MSI-H or dMMR Metastatic Colorectal Cancer

Tremelimumab in Previously Treated Advanced Malignant Mesothelioma

Effect of BRCA1/2 Status on Response to Neoadjuvant Carboplatin in Triple-Negative Breast Cancer

Asparaginase-Associated Pancreatitis in Childhood Acute Lymphoblastic Leukemia

New ASCO Recommendations for Controlling Nausea and Vomiting Related to Cancer Treatment

FDA Grants Venetoclax Breakthrough Therapy Designation for Geriatric Patients With Acute Myeloid Leukemia

Fulvestrant Receives EC Approval as First-Line Therapy for Advanced Breast Cancer

FDA Grants Durvalumab Breakthrough Therapy Designation for Patients With Locally Advanced Unresectable NSCLC

Study Finds HER2 Mutations in 3% of Lung Cancers

Standard-Dose Pembrolizumab Plus Reduced-Dose Ipilimumab in Advanced Melanoma

Association of Bisphosphonate Use and Breast Cancer Risk in Postmenopausal Women

Initial Progression-Free Survival Results From the MYSTIC Trial in Stage IV NSCLC

National Cancer Groups Release Joint Statement to Chart the Future of Cancer Health Disparities Research

Association Between Vasectomy and Prostate Cancer

Breast Cancer Survivor Preferences for Providers of Aspects of Primary Care After Cancer Treatment

Poor Social Functioning in Adolescent and Young Adult Cancer Survivors

Classifying Gastric Cancers by Subtype May Provide Tailored Treatment Options

Genetic Study Identifies Susceptibility Loci Modifying Risk for Breast Cancer After Radiation Therapy for Childhood Cancer

Response to CAR T-Cell Therapy After Ibrutinib in Chronic Lymphocytic Leukemia

Guideline-Based Statin Eligibility and Cancer Risk

Surgery vs Observation in Localized Prostate Cancer: Long-Term Follow-up of PIVOT Trial

NCI-COG Pediatric MATCH Trial to Test Targeted Drugs in Childhood Cancers

FDA Expands Approval of Ipilimumab to Include Pediatric Patients 12 Years and Older With Unresectable or Metastatic Melanoma

COX-2 Inhibitors May Reverse IDO1-Mediated Immunosuppression in Some Cancers

Concurrent Chemotherapy, Proton Therapy May Improve Survival in Patients With Advanced Lung Cancer

New Model for Estimating Glomerular Filtration Rate and Accurately Dosing Carboplatin in Cancer Patients

Neoadjuvant Ado-trastuzumab Emtansine vs Trastuzumab in Early HER2-Positive, HR-Positive Breast Cancer

Social Interaction May Affect Patients’ Response to Chemotherapy

Regionalization and Lung Cancer Operative Mortality in Ontario, Canada

Insurance Approval Rates for Enrollment in Oncology Clinical Trials Increased Under Affordable Care Act

Italian Study of Serotherapy to Prevent GVHD in Pediatric Hematologic Malignancy

Understanding and Managing Radiation-Induced Bystander Effect

Analysis Reveals Genomic Alterations, Oncogenes Driving Medulloblastoma Subtypes

Comparison of MRI vs PET-CT in Multiple Myeloma

Single-Center Trial of Stereotactic Radiosurgery for Completely Resected Brain Metastases

Addition of Cetuximab to Concurrent Chemoradiation in Esophageal Cancer

ASCO Offers Path to Addressing Affordability of Cancer Drugs in New Position Statement

FDA Approves Three-Drug Combination Tablet for Hepatitis C

Understanding of Stage and Cancer Status Among Patients in a Community-Based Cancer Institute

Nivolumab Plus Ipilimumab in Metastatic Renal Cell Carcinoma

Stereotactic Radiosurgery vs Whole-Brain Radiotherapy for Resected Metastatic Brain Disease

MammaPrint Scoring and Indolent Node-Negative Breast Cancer

CDK4/6 Inhibitors Have a Manageable Toxicity Profile, Are Generally Well Tolerated in Patients With Breast Cancer

Neoadjuvant Radiation Reduces Risk of Secondary Tumors in Early-Stage Breast Cancer

Insertion and Deletion Mutations and Immunogenicity in Solid Tumors

Effect of Methotrexate and Corticosteroid Strategies on Neurocognitive Function in Patients With B-Lineage ALL

FDA Approves Neratinib for Extended Adjuvant Treatment of Early-Stage HER2-Positive Breast Cancer

Appropriate Distress Screening and Follow-up Leads to Fewer ER Visits and Hospitalizations in Patients With Cancer

ASTRO Updates Insurance Coverage Recommendations for Proton Therapy

Nivolumab Treatment Beyond Disease Progression in Advanced Melanoma

Impact of Health Insurance and Sociodemographic Status on Survival for AYAs With Cancer

CD33 Splicing Polymorphism and Response to Gemtuzumab Ozogamicin in AML

Cancer Risk May Be Higher Among Holocaust Survivors

Anthracycline-Free Adjuvant Treatment in Early TOP2A-Normal Breast Cancer

Study Demonstrates Potential for Artificial Intelligence and Whole-Genome Sequencing to Scale Access to Precision Medicine

New CDC Report Shows Cancer Death Rates Are Higher in Rural America

FDA’s Advisory Committee Supports CTL019 in Pediatric, Young Adult Patients With B-Cell ALL

Blinatumomab Granted Full Approval to Treat Relapsed or Refractory B-cell Precursor ALL in Adults and Children

FDA Approves First Companion Diagnostic Test to Simultaneously Screen for Multiple NSCLC Therapies

FDA Accepts sNDA for Dasatinib in Pediatric Patients With Philadelphia Chromosome–Positive Chronic-Phase CML

Priority Review Granted for Abemaciclib in the Treatment of Advanced Breast Cancer

Factors Associated With Near-Miss/Safety Incidents in Cancer Radiotherapy

Overall Survival With Nivolumab vs Chemotherapy in Ipilimumab-Refractory Advanced Melanoma

MammaPrint Test Addressed in ASCO Breast Cancer Guideline Update

Narrow Network Insurance Plans More Likely to Exclude Doctors at NCI-Designated and NCCN Member Cancer Centers

Delaying Lymph Node Biopsy After Melanoma Diagnosis May Not Adversely Affect Survival Rates

Effect of Patient-Reported Symptoms on Adherence to Preventive Treatment for Breast Cancer

Current Performance Measures for Cervical Cancer Screening

FDA Grants 510(k) Clearance to Halcyon IMRT Treatment System

FDA Places Clinical Hold on Three Studies Evaluating Pembrolizumab in Multiple Myeloma

Idarubicin vs High-Dose Daunorubicin Induction in Newly Diagnosed Acute Myeloid Leukemia

Adding Evofosfamide to Doxorubicin in Advanced Soft-Tissue Sarcoma

Fat Grafting and Patient-Reported Outcomes in Postmastectomy Breast Reconstruction

FDA Grants Marketing Approval to the Praxis Extended RAS Panel

Effect of Salvage Surgery on Survival in Recurrence After Treatment of Rectal Cancer

Adding Sorafenib to Transarterial Chemoembolization in Hepatocellular Carcinoma

MET Inhibitor Savolitinib in Advanced Papillary Renal Cell Cancer

Adding Midostaurin to Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia With FLT3 Mutation

Interventionist-Guided Weight Loss Program for African American Breast Cancer Survivors

ESMO World GI 2017: Right-Sided Colorectal Tumors: An Internal Radiation Advantage

FDA Clears Expanded Use of Cooling Cap to Reduce Hair Loss During Chemotherapy

FDA Approves Panitumumab for Use in Wild-Type RAS Metastatic Colorectal Cancer

ESMO World GI 2017: Study Explores Association of Mediterranean Diet Components With Advanced Colorectal Polyps

FDA Allows Marketing of Test to Aid in the Detection of Certain Leukemias and Lymphomas

European Commission Expands Use of Ceritinib for First-Line Use in ALK-Positive Advanced NSCLC

ESMO World GI 2017: Pegilodecakin Plus FOLFOX in Advanced Pancreatic Cancer

ESMO World GI 2017: Phase I Data on Anti–PD-1 Antibody BGB-A317 in Hepatocellular Carcinoma

First-Line Cetuximab vs Bevacizumab Plus Chemotherapy in KRAS Wild-Type Advanced Colorectal Cancer

Study Estimates Risks of Breast and Ovarian Cancers in BRCA1/2-Mutation Carriers

Detecting Cancer With Intraoperative Multimodal Optical System

FDA Unveils Plan to Eliminate Orphan Designation Backlog

FDA Takes Steps to Increase Drug Competition to Improve Patient Access

Underused Blood Test Could Improve Treatment for Large Swath of Patients With Colon Cancer

Outcome by Age With Lenvatinib in Radioiodine-Refractory Differentiated Thyroid Cancer

First-Line Nivolumab vs Chemotherapy in Advanced NSCLC With PD-L1 Expression ≥ 5%

EHA 2017: Half of Chronic-Phase Philadelphia Chromosome–Positive CML Patients Stay in Treatment-Free Remission 2 Years After Stopping Nilotinib

Biden Cancer Initiative Launches

EHA 2017: Ixazomib Plus Lenalidomide/Dexamethasone in Newly Diagnosed Multiple Myeloma With No Stem Cell Transplant, Followed by Maintenance Ixazomib

Study Finds Many Health Benefits Linked to Having Health Insurance

Dabrafenib Plus Trametinib in BRAF V600–Mutant Melanoma Brain Metastases

EHA 2017: Updated CTL019 ELIANA Data Show Durable Remission Rates in Children, Young Adults With Relapsed/Refractory B-Cell ALL

ICML 2017: Nivolumab Shows Durable Response in Relapsed or Progressed Classical Hodgkin Lymphoma, Regardless of Brentuximab Vedotin History

EHA 2017: The DYNAMO Study: Duvelisib in Double-Refractory Follicular Lymphoma and Small Lymphocytic Lymphoma

FDA Approves Betrixaban for the Prophylaxis of Venous Thromboembolism

Secondhand Smoke Exposure Among Nonsmoking Cancer Survivors

Brentuximab Vedotin vs Physician’s Choice in CD30-Positive Cutaneous T-Cell Lymphoma

FDA Grants Regular Approval to Dabrafenib and Trametinib Combination for Metastatic NSCLC With BRAF V600E Mutation

Impact of Palliative Care on End-of-Life Services for Patients Dying in a Hospital

Atezolizumab as First-Line or Subsequent Treatment in PD-L1–Selected Advanced NSCLC

FDA Approves Rituximab Plus Hyaluronidase Combination for Treatment of Certain Hematologic Malignancies

Phase III CASCADE Trial of Front-Line Vadastuximab Talirine in AML Discontinued

NCCN Guidelines® Compliance for Chest CT May Reduce False Positives and Decrease Health-Care Spending in Breast Cancer

Canadian Cancer Society Report: Nearly 1 in 2 Canadians Expected to Be Diagnosed With Cancer in Their Lifetime

Digital Technology Preferences of Adolescents and Young Adults With Cancer

WCHN Launches Trial to Screen Newly Diagnosed Patients With Diabetes for Early-Stage Pancreatic Cancer

Effect of Postdiagnosis Aspirin and Other NSAIDs on Survival in Colorectal Cancer

Accelerated vs Standard Epirubicin and Capecitabine vs CMF in Adjuvant Therapy for Breast Cancer

ICML 2017: 3-Year Follow-up Showed Fourfold Progression-Free Survival Benefit With Ibrutinib vs Temsirolimus at First Relapse in Mantle Cell Lymphoma

ICML 2017: Data From the TRANSCEND Trial of JCAR017 in Relapsed and Refractory Aggressive B-Cell Non-Hodgkin Lymphoma

ICML 2017: Phase IIIb MAGNIFY Study of Lenalidomide and Rituximab Combination in Relapsed/Refractory Follicular and Marginal Zone Lymphoma

ICML 2017: Brentuximab Vedotin in Combination With Nivolumab in Patients With Relapsed or Refractory Hodgkin Lymphoma

ICML 2017: ADCT-402 Demonstrates Encouraging Antitumor Activity in Relapsed/Refractory Non-Hodgkin Lymphoma

Equivalence Trial of Neoadjuvant Trastuzumab Biosimilar CT-P6 vs Trastuzumab in HER2-Positive Breast Cancer

FDA Approves Aminolevulinic Acid Hydrochloride as an Optical Imaging Agent Indicated in Gliomas

ICML 2017: Phase III GENUINE Trial: Ublituximab Plus Ibrutinib in High-Risk CLL

ICML 2017: Triplet Combination of Umbralisib, Ublituximab, and Ibrutinib in CLL/SLL/NHL

ICML 2017: Phase II Trial of Tazemetostat in Relapsed or Refractory Follicular Lymphoma and DLBCL

Effect of Embedding Palliative Care in an Oncology Clinic

Trends in Surgery After Initial Lumpectomy for Breast Cancer

SNMMI 2017: Preclinical Targeted Photodynamic Therapy Shown Highly Effective Against Prostate Cancer

SNMMI 2017: Combining PRRT With a PARP Inhibitor May Slow Neuroendocrine Tumor Growth

SNMMI 2017: Imaging Metastatic Breast and Prostate Cancer Using Dual-Agent PET/MRI With Time of Flight

Impact of Subsidies on Use of Oral Immunomodulatory Drugs in Medicare Beneficiaries With Myeloma

Ceritinib vs Chemotherapy in Previously Treated ALK-Rearranged NSCLC

FDA Approves Daratumumab in Combination With Pomalidomide and Dexamethasone for Relapsed or Refractory Multiple Myeloma

SNMMI 2017: Immuno-PET Shows Promise for Detecting and Treating Pancreatic Tumors, Other Solid Tumors

SNMMI 2017: Personalized PRRT Improves Radiation Delivery to Neuroendocrine Tumors

SNMMI 2017: PET/CT, Clinical Management, and Disease Detection in Prostate Cancer

High-Dose First-Line Trastuzumab Maintenance in Metastatic HER2-Positive Gastric Cancer

PD-L2 Expression and Clinical Response to Pembrolizumab in Head and Neck Cancer

CancerCare Establishes Patient Values Initiative, Releases Focus Group Assessment

ASTRO Issues Guideline for Use of Stereotactic Radiation in Early-Stage Lung Cancer

Dutch Study Assesses Long-Term Risk of HPV-Related Carcinoma and Premalignancies After CIN3 Diagnosis

Combination of Buparlisib and Fulvestrant in Postmenopausal Women With Advanced Breast Cancer

Vital Options International Introduces Free eBook, The Cancer Concierge

AACR Publishes First Set of Screening Recommendations Emerging From Childhood Cancer Predisposition Workshop

Pembrolizumab in Solid Tumors With Mismatch-Repair Deficiency

Association of EGFR Copy Number Gain and Outcome With Gefitinib in Advanced Esophageal Cancer

Adding Abemaciclib to Fulvestrant in Hormone Receptor–Positive, HER2-Negative Breast Cancer

Oncologist Barbara L. McAneny, MD, FASCO, MACP, Elected AMA President-Elect

First Analysis of AACR Project GENIE Data Published

ASCO 2017: SWOG Clinical Trials Have Added More Than 3 Million Years of Life for Patients With Cancer

Sacituzumab Govitecan in Previously Treated Patients With Metastatic NSCLC

Melanoma-Specific Survival With Completion Dissection vs Observation for Sentinel Node Metastasis

ASCO 2017: I-SPY 2 Trial: Combination of Pembrolizumab Plus Standard Neoadjuvant Therapy in High-Risk Breast Cancer

FDA Requests Removal of Oxymorphone Hydrochloride for Risks Related to Abuse

ASCO 2017: Ibrutinib Plus Cellular Therapy CTL119 May Lead to Complete Remissions in CLL

ASCO Congratulates NIH Director Francis Collins on Remaining in Critical Leadership Position

ALEX Trial: Alectinib vs Crizotinib in Untreated Advanced ALK-Positive NSCLC

ASCO 2017: Higher Gut Bacteria Diversity Tied to Slower Metastatic Melanoma Progression

European Commission Approves Nivolumab for Previously Treated, Locally Advanced, Unresectable or Metastatic Urothelial Cancer

ASCO 2017: Adding PEGPH20 to Standard Treatment in Metastatic Pancreatic Cancer May Delay Disease Progression

ASCO 2017: Implementing Cost Transparency in Oncology

ASCO 2017: Many Emergency Department Visits Among Patients With Cancer Appear Preventable

ASCO 2017: Impact of Patient Age on Molecular Alterations in Colorectal Tumors

ASCO's TAPUR Study Continues Its Expansion of Sites, Participants, and Collaborators

Tumor Microvessel Density and Outcome With Bevacizumab in Ovarian Cancer

Dinutuximab vs Temsirolimus in Combination Therapy for Children With Refractory or Relapsed Neuroblastoma

T2:ERG and PCA3 RNA Urinary Testing for Detecting Aggressive Prostate Cancer

Effect of Previous Radiotherapy on Outcome With Pembrolizumab in NSCLC

ASCO 2017: Research Suggests Possible New Treatment for EGFR-Positive Lung Cancer

ASCO 2017: Early Research Suggests First Immunotherapy for Mesothelioma on the Horizon

OlympiAD Trial: Olaparib in Metastatic Breast Cancer With Germline BRCA Mutation

LATITUDE Trial: Adding Abiraterone and Prednisone to Androgen-Deprivation Therapy in Metastatic Castration-Sensitive Prostate Cancer

ASCO 2017: BCMA-Specific CAR T-Cell Therapy Sends Relapsed/Refractory Multiple Myeloma Into Lasting Remission in an Early Trial

ASCO 2017: ALEX Study: Alectinib Halts Lung Cancer Growth More Than a Year Longer Than Crizotinib

ASCO 2017: The APHINITY Trial: Adding a Second HER2 Blocker May Lower Chance of Invasive Breast Cancer for Some Women

ASCO 2017: The IDEA Collaboration: Global Study Sets New Risk-Based Standard to Personalize Chemotherapy for Colon Cancer After Surgery

ASCO 2017: Web-Based System for Self-Reporting Symptoms Helps Patients Live Longer

ASCO 2017: OlympiAD Trial: Olaparib Slows Growth of BRCA-Related Metastatic Breast Cancer

ASCO 2017: Larotrectinib Shows Durable Efficacy Across Diverse Pediatric and Adult Cancers

ASCO 2017: ProfiLER Trial: Routine Genomic Testing Feasible, but Only a Subset of Patients May Benefit

ASCO 2017: New High-Intensity Genomic Sequencing Approach Detects Circulating Tumor DNA at a High Rate

ASCO 2017: Pregnancy After Breast Cancer Does Not Increase Chance of Recurrence

ASCO 2017: LATITUDE Trial: Addition of Abiraterone to Standard Hormonal Therapy Improves Outcomes in Newly Diagnosed Metastatic Prostate Cancer

ASCO 2017: STAMPEDE Trial: Adding Abiraterone to Standard Treatment Improves Survival in Advanced Prostate Cancer

ASCO 2017: Remote Therapy Program Improves Quality of Life, Lowers Distress After Cancer Diagnosis

ASCO 2017: Single-Dose Radiotherapy as Effective as Multiple Fractions in Relieving Symptoms of Spinal Cord Compression

ASCO 2017: Low Testosterone Level After Testicular Cancer Is Common, Linked to Chronic Health Problems

ASCO 2017: Conquer Fear Intervention Lowers Young Breast Cancer Survivors’ Fear of Cancer Recurrence

ASCO 2017: Steady Decrease in Severe Health Problems for Childhood Cancer Survivors

ASCO 2017: CALM Intervention Relieves Distress in Patients With Advanced Cancer

ASCO Announces CancerLinQ Partnerships With the FDA and the NCI

Twitter Use at the ASCO Annual Meeting

ATS 2017: Among All Cancers, Lung Cancer Appears to Put Patients at Greatest Suicide Risk

Spanish Analysis of Prognostic Impact of MRD-Negative Status in Multiple Myeloma

Japanese Phase III Trial of Alectinib vs Crizotinib in ALK-Positive NSCLC

Image-Guided Biopsies Accurately Identify Patients With Breast Cancer Who Achieve Pathologic Complete Response Following Neoadjuvant Therapy

Study Finds Hypofractionated Whole-Breast Irradiation Leads Breast Cancer Radiation Therapies in Cost-Effectiveness, Quality of Life

Breast Cancer Risk and Histologic Findings in Serial Benign Biopsies

Clinical Implications of Luminal and Basal Subtyping of Prostate Cancer

Pembrolizumab in Advanced PD-L1–Positive Endometrial Cancer

FDA Broadens Ceritinib Indication to Previously Untreated ALK-Positive Metastatic NSCLC

Final Overall Survival Results of TH3RESA Trial in Breast Cancer

Lack of Access to Transfusions Limits Hospice Use by Patients With Blood Cancer

ASCO and CAP Invite Comment on Focused Update to HER2 Testing Guideline in Breast Cancer

In Remembrance of H. Jean Khoury, MD, FACP

Non–V600 BRAF Mutations in Metastatic Colorectal Cancer

Tai Chi Chih vs Cognitive Behavioral Therapy for Insomnia in Breast Cancer Survivors

ASCO and Other Oncology, Medical Societies Speak Out Against White House’s Proposed Budget Cuts

FDA Grants Priority Review to sBLA for Pembrolizumab in Recurrent or Advanced Gastric or GEJ Adenocarcinoma

Effect of Fixed Second Appointments on Breast Cancer Screening Attendance

Complications From Thyroid Cancer Surgery More Common Than Once Thought

AKT Inhibitor Activity in AKT1-Mutant Solid Tumors

FDA Grants Accelerated Approval to Pembrolizumab for First Tissue/Site-Agnostic Indication

One in Five Cancers Diagnosed in the United States Is a Rare Cancer

FDA OCE Launches Drug Information Soundcast in Clinical Oncology (DISCO)

Racial Differences in Risk of Interval Colorectal Cancer

Outcomes in Patients With Double-Hit Lymphoma After First Complete Remission

Revisions to the International Neuroblastoma Response Criteria

Are Oncologists Discussing Exercise With Patients?

First Extensive Immune Profiling of Sarcomas Shows Possible Susceptibility to Immunotherapy

Economic Impact of Chronic Conditions on Cancer Survivors

RECIL 2017: New Response Evaluation Criteria in Lymphoma Clinical Trials

Study on Women Living With Metastatic Breast Cancer

AUA 2017: Studies Highlight Shifts in Prostate Cancer Screening and Management

Alcohol Consumption May Be Associated With Higher Risk of Breast Cancer in African American Women

AUA 2017: Phase III Study of Blue Light Cystoscopy With Optical Imaging Agent in Bladder Cancer

Blended Cognitive Behavior Therapy and Fear of Recurrence in Cancer Survivors

MEK Inhibitor Selumetinib and Docetaxel in KRAS-Mutant Advanced NSCLC

FDA Approves Pembrolizumab for Advanced or Metastatic Urothelial Carcinoma

AUA 2017: Association of Oncotype DX Genomic Prostate Score Test With Prostate Cancer–Specific Death and Metastases in Early-Stage Disease

AUA 2017: Studies Examine Bladder Cancer Risk and Mortality in E-Cigarette and Traditional Smokers

AUA 2017: New Studies Demonstrate Impact of BRCA, DNA Repair Gene Mutations in Prostate Cancer

Durvalumab With Olaparib or Cediranib in Women’s Cancers

Impact of Expert Pathologic Review on Lymphoma Diagnoses

Brigatinib in Advanced Crizotinib-Refractory ALK-Positive NSCLC

ASCO 2017: Chance of Colon Cancer Recurrence Nearly Cut in Half in Patients Who Consume Nuts

ASCO 2017: HPV Vaccination May Reduce Oral HPV Infections but Is Still Underutilized

ASCO 2017: Gefitinib Treatment Can Delay Recurrence of Intermediate-Stage Lung Cancer

ASCO 2017: Healthy Lifestyle After Colon Cancer Diagnosis Helps Extend Survival

ASCO 2017: Increase in Early-Stage Cancer Diagnoses After Implementation of the Affordable Care Act

ASCO 2017: Adjuvant Capecitabine May Extend Survival in Biliary Tract Cancer

New Canadian Guideline Provides Advice to Physicians to Avoid Overprescribing of Opioids

First-In-Human Clinical Trial Aims to Extend Remission for Children and Young Adults With Leukemia Treated With T-Cell Immunotherapy

Surveillance and Colorectal Cancer Risk in Patients With Intermediate-Risk Adenomas

Long-Term Follow-up of Intergroup Exemestane Study

First-in-Class T-Cell Stimulator Varlilumab in Advanced Solid Tumors

Hypofractionated Radiotherapy vs Conventionally Fractionated Radiotherapy in Early-Stage Glottic Cancer

Delaying Colonoscopy for 9 Months or More After Positive Fecal Screening Test May Increase Risk of Colorectal Cancer

Hypofractionated Postmastectomy Radiation in Breast Cancer

Changes in HER2 Breast Cancer Testing According to 2007 and 2013 ASCO/CAP Guidelines

Reduced-Intensity vs Standard Conditioning Followed by ASCT in Myelodysplastic Syndrome

FDA Approves Ribociclib/Letrozole Co‑Pack for Postmenopausal Patients With Advanced or Metastatic Breast Cancer

ONS 2017: Hospital-Wide Initiative to Standardize the Administration of Vinca Alkaloids Using a Mini-Bag, Side-Arm Technique

ASCO-NCI Collaboration Finds Widespread Benefits of Centralizing Coverage Analyses for Multisite Clinical Trials

ASCO Remembers Robert L. Comis, MD, FASCO

Cost of Hospitalization for Cancer-Related Neutropenia or Fever

Adding Pertuzumab to Trastuzumab/Capecitabine in Pretreated HER2-Positive Metastatic Breast Cancer

FDA Approves Pembrolizumab as First-Line Combination Therapy With Pemetrexed and Carboplatin for Metastatic Nonsquamous NSCLC

ESTRO 2017: Study Suggests Role for Radiotherapy in Extending Survival in Patients With Early-Stage Pancreatic Cancer

ESTRO 2017: HDR Brachytherapy in Prostate Cancer Does Not Cause Higher Toxicity, Results in High Patient Satisfaction

ESTRO 2017: ESTRO Announces GIRO, a Project to Save 1 Million Lives in Under 20 Years

ESTRO 2017: Cervical Cancer Survivors Frequently Suffer From Long-Term Fatigue, Insomnia, and Hot Flashes

Update to Guideline for Management of Fever and Neutropenia in Children With Cancer and HSCT Recipients

USPSTF Recommendation on Screening for Thyroid Cancer

FDA Grants Accelerated Approval to Avelumab for Urothelial Carcinoma

ELCC 2017: Prospective Study Shows Concordance of EGFR Mutation Detection Between ctDNA and Tumor Samples

ELCC 2017: Specific Immune Cell Profiles Potentially Identify Patients With Lung Cancer Responsive to Anti–PD-1 Immunotherapy

ELCC 2017: Ensartinib Demonstrates CNS Activity in ALK-Positive NSCLC

ELCC 2017: Development and Validation of Lung Toxicity Prediction Models Aids Effective Use of Radiotherapy in NSCLC

Prognostic and Predictive Effects of TP53 With KRAS or EGFR Mutation Status in NSCLC

Final, 10-Year Follow-up of Phase III Trial on Adding Gemcitabine to Adjuvant Therapy in Breast Cancer

ELCC 2017: Study Shows White Blood Cell–Boosting Drugs Safe During Small Cell Lung Cancer Chemoradiotherapy

ELCC 2017: Some Patients With Lung Cancer Benefit From Immunotherapy Even After Disease Progression

ELCC 2017: Osimertinib Improves Symptoms in Advanced Lung Cancer

ELCC 2017: White Blood Cell Count May Predict Response to Lung Cancer Immunotherapy

Pembrolizumab in Relapsed or Refractory Classical Hodgkin Lymphoma

PD-L1 Expression and Radiation Resistance in Head and Neck Squamous Cell Carcinoma

IMPAKT 2017: Few Variations in Somatic Mutations Observed Between Pregnant and Nonpregnant Patients With Breast Cancer

IMPAKT 2017: High Baseline Tumor-Infiltrating Lymphocyte Levels Signal Superior Responses in HER2-Positive Breast Cancer

IMPAKT 2017: Luminal Androgen Receptor Subtype of Triple-Negative Breast Cancer Demonstrates Sensitivity to CDK4/6 Inhibition

WHO to Begin Pilot Prequalification of Biosimilars for Cancer Treatment

ASCO Provisional Clinical Opinion: Second-Line Hormonal Therapy for Chemotherapy-Naive Castration-Resistant Prostate Cancer

Germline Genetic Testing and Treatment Decisions in Early-Stage Breast Cancer

AMA Statement on House Passage of American Health Care Act 

AANS 2017: Seizure Outcome After Surgical Resection of Insular Glioma

AANS 2017: Genetic Underpinnings of Desmoplastic Infantile Ganglioglioma/Astrocytoma

New Spanish-Language Videos and Brochures From ASTRO Provide an Overview of Radiation Therapy

Tumor CD274 (PD-L1) Expression and Survival With Aspirin Use in Colorectal Cancer

Adding Bevacizumab to Paclitaxel-Carboplatin in Recurrent Platinum-Sensitive Ovarian Cancer

Genomic Intratumor Heterogeneity and Evolution of NSCLC Tumors

Long-Term Follow-up of German Hodgkin Study Group Trials in Early-Stage Hodgkin Lymphoma

ELCC 2017: Men May Need More Frequent Lung Cancer Screening Than Women

Children Conceived After Fertility Treatments May Be at Increased Risk for Pediatric Cancers

Potential Predictive Biomarker of Response to Crizotinib in Lung Cancer

ASCO Applauds Congress for Providing Additional $2 Billion in NIH Funding

Higher Costs for Complex Cancer Surgery May Be an Indicator of Lower-Quality Care

European Commission Approves Nivolumab for Head and Neck Squamous Cell Carcinoma Progressing on or After Platinum-Based Therapy

ASCO/CCO Clinical Practice Guideline Update: Adjuvant Therapy for Resected Non–Small Cell Lung Cancers

Perioperative Hepatic Arterial Infusion Pump Chemotherapy After Resection of Colorectal Liver Metastases

Novel Imaging Method for Predicting Immunotherapy Response

FDA Approves Durvalumab in Locally Advanced or Metastatic Urothelial Carcinoma

Prostate-Specific Antigen Testing Rates Appear to Level Off After Recent Drop

Complete Surgical Metastasectomy for Patients With Metastatic Renal Cell Carcinoma May Extend Life Expectancy

Nomogram for Early Mortality in Metastatic Colorectal Cancer

Nivolumab in Advanced Hepatocellular Carcinoma

Lenalidomide Maintenance in Older Patients With Diffuse Large B-Cell Lymphoma

FDA Approves Brigatinib for Metastatic ALK-Positive Non–Small Cell Lung Cancer

FDA Approves Midostaurin in Combination With Chemotherapy for Newly Diagnosed FLT3-Positive Acute Myeloid Leukemia

Benefit of Survivorship Care Plans Among Low-Income, Predominantly Latina Breast Cancer Survivors

Second-Line Pazopanib vs Weekly Paclitaxel in Relapsed or Progressive Urothelial Cancer

Second Cancers May Be Deadlier in Pediatric, Adolescent, and Young Adult Patients

FDA Grants Lorlatinib Breakthrough Therapy Designation for ALK-Positive Metastatic Non–Small Cell Lung Cancer

New 'Bone-in Culture Array' Tests Therapies for Breast Cancer Metastasis

FDA Expands Approved Use of Regorafenib for Hepatocellular Carcinoma

ELCC 2017: Patients With Lung Cancer Treated With PD-1/PD-L1 Checkpoint Inhibitors May Experience Adverse Events After Influenza Vaccination

Joint Position Statement on Management of Aromatase Inhibitor–Associated Bone Loss in Postmenopausal Women With Hormone-Sensitive Breast Cancer

Clinical Practice Guidelines on the Evidence-Based Use of Integrative Therapies During and After Breast Cancer Treatment

Cost-Effectiveness and Cost Savings of a Hospital-Based Palliative Care Program

Estimates of Cancer Population Reference Values for PROMIS Patient-Reported Outcome Domains

Long-Term Outcome With Combined-Modality vs Systemic Treatment for Unresectable Colorectal Liver Metastases

FDA Takes Action Against 14 Companies for Selling Illegal Cancer Treatments

ILC 2017: Selective Internal Radiation Therapy vs Sorafenib in Hepatocellular Carcinoma

Reduced-Dose Radiotherapy for HPV-Positive Oropharyngeal Carcinoma

Prophylactic Cranial Irradiation vs Observation in Extensive-Disease Small Cell Lung Cancer

Noninvasive Imaging Test May Accurately Rule Out Kidney Cancers

NCCN Survey Reveals Oncology Community Professionals’ Concerns About Financial Distress, Access to Care

Long-Term Outcome With Combined-Modality vs Systemic Treatment for Unresectable Colorectal Liver Metastases

Neoadjuvant Chemotherapy for Breast Cancer and Risk for Local Metastases

Racial/Ethnic Disparities in End-of-Life Care for Patients With Ovarian Cancer

Low Cervical Cancer Screening Rates Found Among Women With Severe Mental Illness

Multigene Test Could Help Extend Life Expectancy for Women at Risk of Hereditary Breast Cancer

Efficacy Analysis of ABC Breast Cancer Trials of Adjuvant Taxane With/Without Anthracycline in HER2-Negative Disease

Metastatic Uveal Melanoma Response to Adoptive Transfer of Autologous Tumor-Infiltrating Lymphocytes

Higher Rates of Bone Metastases and Increased Risk of Death in Follicular and Medullary Thyroid Cancer

Breast Cancer Rates Increasing Among Asian Americans

Predictors of Adherence to Oral Chemotherapy

21-Gene Assay Score and Chemotherapy Decision-Making in Node-Positive Early Breast Cancer

Study Associates Comorbidities With Survival Outcomes in Women With Ovarian Cancer

Update to ASCO Clinical Practice Guideline on Potentially Curable Pancreatic Cancer

10-Year Outcomes With Two Dose Levels of Imatinib in Unresectable or Metastatic GIST

FDA Permits Marketing for Digital Pathology Solution for Primary Diagnostic Use

FDA Grants Atezolizumab Accelerated Approval as Initial Treatment for Some Advanced Bladder Cancers

New ASTRO Guideline Establishes Standard of Care for Curative Treatment of Oropharyngeal Cancer With Radiation Therapy

Medical Groups Unite in Support of March for Science

Conditional Survival After Initial Diagnosis and Treatment of Stage III Melanoma

Effect of Radiotherapy Boost for Ductal Carcinoma in Situ After Whole-Breast Radiotherapy

FDA Removes Risk Evaluation and Mitigation Strategy Requirements for Erythropoiesis-Stimulating Agents

Satisfaction With Surgical Decision-Making in Women Considering Contralateral Prophylactic Mastectomy for Breast Cancer

Study Finds Vaccine-Chemotherapy Combination Prolongs Overall Survival in Glioblastoma

Possible Link Between Androgen-Deprivation Therapy and Dementia

Predicting Metastatic Disease After Radical Prostatectomy

U.S. Preventive Services Task Force Seeks Comments on Draft Recommendation Statement on Screening for Prostate Cancer

Ratio of T-Cell Invigoration to Tumor Burden Associated With Immunotherapeutic Response

Cigarette Smoking and Survival in Pancreatic Cancer

ASCO Research Statement: Tapping the Potential of Observational Research

Preclinical Research Suggests Potential Therapy for 'Chemobrain'

New ACS CAN Report Examines Expected Patient Costs for Common Cancer Diagnoses

Spanish Trial Shows Benefit of Vinflunine Maintenance in Advanced Urothelial Carcinoma

Trends in Thyroid Cancer Incidence and Mortality in the United States

Blinatumomab After Failure of TKI Treatment in B-Precursor Acute Lymphoblastic Leukemia

Potential Therapeutic Target for Malignant Teratoid/Rhabdoid Tumors Identified in Preclinical Study

Breast Cancer Treatment Options Vary Widely in Cost-Effectiveness

Studies Find Disparity in Life Expectancy Widening Between Wealthy and Poor Americans

Final Results of European Trial in Mucosa-Associated Lymphoid Tissue Lymphoma

Study Finds Link Between Telomere Length and Neighborhood Circumstances

Annual Report to the Nation: Cancer Death Rates Continue to Decline

Avelumab in Refractory Metastatic Urothelial Carcinoma

Lenalidomide, Bortezomib, and Dexamethasone With or Without HCT in Younger Patients With Multiple Myeloma

FDA Grants Marketing Authorization for Ipsogen JAK2 RGQ PCR Kit to Detect JAK2 Genetic Mutations

AACR 2017: Telomere Length May Predict Cancer Risk, According to Large Epidemiologic Study

AACR 2017: Interim Results of Phase Ib/II Trial of Neratinib in Combination With Ado-trastuzumab Emtansine in HER2-Positive Metastatic Breast Cancer

Patient-Reported Outcomes With Immediate Implant-Based or Autologous Breast Reconstruction

Cardiac Events After Radiotherapy for Locally Advanced Lung Cancer

AACR 2017: PRMT1 Identified as Potential Druggable Target for Pancreatic Cancer

AACR 2017: Minority Patients With Colorectal Cancer Report Higher Burden of Poor Quality-of-Life Than Whites

AACR 2017: Combination Immunotherapies Show Clinical Activity in Metastatic RCC in Pilot Study

Final Results of European Intergroup Trial of Early PET-Adapted Treatment in Hodgkin Lymphoma

Use of ‘Triggers’ for Palliative Care Consultation on Solid Tumor Oncology Service

Total Laparoscopic Hysterectomy vs Total Abdominal Hysterectomy for Stage I Endometrial Cancer

AACR 2017: Ipilimumab/CVA21 Combination Treatment Shows Promise in Advanced Melanoma

AACR 2017: Adding the IDO-Pathway Inhibitor Indoximod to Pembrolizumab Improved Response Rate in Melanoma

AACR 2017: IDH-Mutant Cancers May Be More Amenable to Treatment With PARP Inhibitors Than IDH Inhibitors, According to Preclinical Findings

Pembrolizumab in Platinum- and Cetuximab-Refractory Head and Neck Cancer

Mercaptopurine Ingestion Habits and Risk of Relapse in Children With Acute Lymphoblastic Leukemia

Ado-trastuzumab Emtansine vs Taxane in HER2-Positive Advanced Gastric Cancer

AACR 2017: Patients With Triple-Negative Breast Cancer Who Responded to Atezolizumab Had Long-Term Survival Benefit

AACR 2017: 5-Year Survival Rate for Nivolumab-Treated Advanced Lung Cancer Higher Than Historical Rate in Early-Phase Trial

AACR 2017: Combination of Nivolumab and Ipilimumab Improved Overall Survival in Advanced Melanoma

Effect of Vitamin D and Calcium Supplementation on Cancer Incidence in Postmenopausal Women

Survival in Advanced Melanoma With Ipilimumab at 10 mg/kg vs 3 mg/kg

Palbociclib Receives FDA Approval and Expanded Indication for First-Line Metastatic Breast Cancer

AACR 2017: Combination HER2-Targeted Therapy Effective in Heavily Pretreated HER2-Positive Colorectal Cancer

AACR 2017: Addition of TTFields to Temozolomide Treatment Improves Survival for Patients With Glioblastoma

AACR 2017: Cancer Type and Mutation Identity Influenced Response to Neratinib in a Basket Clinical Trial

High-Throughput Genomics May Improve Outcomes in Difficult-to-Treat Cancers

Pediatric Oncology Patient and Parent Attitudes on Early Palliative Care Integration

Anti–Trop-2 Antibody Drug Conjugate in Heavily Pretreated Metastatic Triple-Negative Breast Cancer

Racial and Ethnic Disparities in Gene-Expression Profiling Tests in Breast Cancer

New NCCN Radiation Therapy Compendium Aids in Decision-Making for Patients With Cancer

FDA Grants Osimertinib Full Approval in Metastatic EGFR T790M Mutation–Positive NSCLC

First-in-Human Clinical Trial of ONC201 in Patients With Refractory Solid Tumors

Significant Increase in Number of Women Tested for BRCA Gene, but Many High-Risk Patients Remain Unidentified

Pembrolizumab in PD-L1–Positive Malignant Pleural Mesothelioma

Assessment of Immunohistochemistry Assays for PD-L1 Expression in NSCLC

Intestinal Microbiota and Relapse After Allogeneic Hematopoietic Cell Transplantation

Palliative Care Consultations for Patients With Advanced Cancers May Reduce Hospitalization and Improve Quality of Care

Interleukin-15 Levels Associated With Lymphoma Response to CAR T-Cell Treatment

Effect of Polypharmacy on Adherence to Adjuvant Endocrine Therapy for Breast Cancer

3-Year Follow-up of Japanese Trial of Alectinib in ALK-Positive NSCLC

FDA Approves Maintenance Niraparib for Recurrent Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

ASCO and Cancer Care Ontario Update Guideline on Radiation Therapy for Prostate Cancer

New Study Finds Most Cancer Mutations Due to Random DNA-Copying Errors

Hypofractionated vs Conventional Radiotherapy for Localized Prostate Cancer

Impact of 70-Gene Signature on Adjuvant Chemotherapy Decisions in Breast Cancer

Analysis of High-Risk Subgroup in ASSURE Trial of Sunitinib or Sorafenib in Renal Cell Carcinoma

New Supportive Care Resources From NCCN Help Patients With Cancer Confront Distress

Major Pharmaceutical Companies Collaborate in NCCN Research Project

Delays in Radiotherapy for Head and Neck Cancer in Insured and Indigent Populations

Celecoxib or Celecoxib/Zoledronic Acid in Men Initiating Hormone Therapy for Prostate Cancer

FDA Approves Avelumab for Metastatic Merkel Cell Carcinoma

SSO 2017: Preclinical Trial Shows Intratumoral Vaccination Induces Antitumor Response in Pancreatic Cancer

IASLC Endorses Tobacco Reform Report Outlining Progress Toward Ending Adult Cigarette Smoking

Multikinase Inhibitor Treatment Responses in Patients With RET-Rearranged NSCLC

Suboptimal BMD Evaluation in Postmenopausal Women With Early-Stage Breast Cancer Receiving Aromatase Inhibitors

Adding Vandetanib to Gemcitabine in Locally Advanced or Metastatic Pancreatic Carcinoma

Risk of Second Cancer in Hodgkin Lymphoma Survivors

Testosterone Replacement Therapy and Risk of Prostate Cancer

Japanese Phase II Trial of Nivolumab in Previously Treated Advanced Esophageal Cancer

Association of Metformin Use for Diabetes With Outcomes in HER2-Positive Breast Cancer

ASCO Releases Its State of Cancer Care in America: 2017 Report

Dexamethasone Mouthwash in Preventing Everolimus-Related Stomatitis in Women With Breast Cancer

Thoracic 2017: SBRT Offers Curative Option for Patients With Lung Cancer Aged 80 and Older

Thoracic 2017: Updated Data Confirm Benefits of Single-Fraction SBRT for NSCLC

Belgian Study Combines BRAF and MEK Inhibition in Advanced BRAF 600–Mutant Melanoma

Adding Temozolomide to Short-Course Radiotherapy in Older Patients With Glioblastoma

Thoracic 2017: Combination of Radiation and Immune Checkpoint Therapy Holds Potential for Lung Cancer

Thoracic 2017: Racial Disparities Persist in Treatment and Survival of Early-Stage Lung Cancer

Thoracic 2017: Proton Therapy Offers New Treatment Possibility for Recurrent Lung Cancer

Common Genetic Variation and Risk of Gallbladder Cancer in India

Antisense Oligonucleotide Custirsen Combined With Docetaxel and Prednisone in Metastatic Prostate Cancer

Thoracic 2017: Genetic Profile of Treatment-Resistant Lung Cancer More Variable Than Previously Thought

Thoracic 2017: Biomarker Test Shows Cancer Recurrence Months Before CT Scans

ASCO Statement: President's Budget Will Devastate U.S. Research Enterprise

Association of DNA Thioguanine Nucleotide Concentration and Outcome During Maintenance Therapy for Childhood ALL

SGO 2017: Hospital Readmission Metrics May Not Be an Ideal Measure in Ovarian Cancer Cases

SGO 2017: Parental Concern About Lack of Sexual Activity Declining as Reason Not to Vaccinate Children Against HPV

SGO 2017: New Immunotherapy Axalimogene Filoslisbac Shows Positive Results in Cervical Cancer

SGO 2017: Secondary Endpoint Results of Phase III ENGOT-OV16/NOVA Trial of Niraparib in Recurrent Ovarian Cancer

FDA Approves Pembrolizumab for Relapsed or Refractory Classical Hodgkin Lymphoma in Adult and Pediatric Patients

Researchers Find Evidence-Based Radiation Treatment After Lumpectomy Leads to High-Quality, High-Value Care

Busulfan and Melphalan vs Carboplatin, Etoposide, and Melphalan in High-Risk Neuroblastoma

Factors Associated With Early Death in Childhood Cancer

Cancer Care Ontario and ASCO Clinical Practice Guideline: Use of Adjuvant Bisphosphonates and Other Bone-Modifying Agents in Breast Cancer

Benefit of Imatinib in Chronic Myeloid Leukemia Persists Long Term in IRIS Trial

European Cohort Study of Vasectomy and Prostate Cancer Risk

Binimetinib vs Dacarbazine: Which Was More Effective in NRAS-Mutant Melanoma?

Evidence of Stage Shift in Ovarian Cancer Detected in UK Screening Study

Blinatumomab vs Chemotherapy in Advanced Acute Lymphoblastic Leukemia

Preclinical Study Finds SPOP Mutation Drives Prostate Cancer Subtype

ASCO Honors Researchers and Scientists for Significant Advancements in Cancer Treatment and Care

FDA Approves Ribociclib as Initial Therapy for Hormone Receptor–Positive, HER2-Negative Advanced or Metastatic Breast Cancer

ACC.17: History of Exercise Helps Prevent Heart Disease After Breast Cancer

Key Gene Controlling Tumor Growth in Gliomas Pinpointed

Use of Evidence-Based Prostate Cancer Imaging in an Integrated Health-Care System

Dutch Study Examines Effect of Internet-Based Cognitive Behavioral Therapy on Sexual Functioning in Breast Cancer Survivors

UK Trial Shows No Survival Benefit in Adding Pravastatin to Standard Chemotherapy in Small Cell Lung Cancer

Osimertinib in EGFR Inhibitor–Pretreated T790M-Positive Advanced NSCLC

Study Identifies How Cancer Cells May Develop Resistance to FGFR Inhibitors

Neoadjuvant Dual HER2 Blockade in HER2-Enriched Early Breast Cancer

Barriers to Clinical Trial Accrual Include Trial Sponsorship and Time to Enrolling First Patient, Study Finds

Cisplatin-Based Chemotherapy in Pediatric Extracranial Malignant Germ Cell Tumors

Ronald A. DePinho, MD, to Resign as President of MD Anderson

Study Finds No Evidence of Cytomegalovirus in Glioblastoma and Other High-Grade Gliomas

Risk of Adverse Health Outcomes in Testicular Cancer Survivors After Cisplatin-Based Chemotherapy

Late Relapse of Classical Hodgkin Lymphoma in German Hodgkin Study Group Trials

ASCO Endorses ACS Head and Neck Cancer Survivorship Care Guideline

Decreasing but Still Elevated Risk for Subsequent Neoplasms in Survivors of Childhood Cancers

ASCO Quality Care 2017: Reducing Overuse of Colony-Stimulating Factors in Febrile Neutropenia Without Compromising Patient Safety

ASCO Quality Care 2017: Reduction in Chemotherapy Errors Through Improvement Science

ASCO Quality Care 2017: Cost and Survival Analysis Before and After Implementation of Clinical Pathways for Patients With Stage IV NSCLC

Nivolumab in Previously Treated Unresectable Metastatic Squamous Cell Carcinoma of the Anal Canal

Can Histone Deacetylase Inhibitors Reverse Resistance to Angiogenesis Inhibitors?

Financial Stress in Patients With Locally Advanced Head and Neck Cancer

Comparison of Pharmaceutical, Psychological, and Exercise Treatments for Cancer-Related Fatigue

Effect of Scalp Cooling on Hair Loss in Women Receiving Nonanthracycline Chemotherapy for Breast Cancer

Hormone Maintenance Therapy in Low-Grade Serous Cancer of the Ovary or Peritoneum

Adding Rituximab to Standard Therapy in Interim PET–Positive Advanced Hodgkin Lymphoma

Phase III APHINITY Study: Adjuvant Pertuzumab/Trastuzumab/Chemotherapy Increased Invasive Disease–Free Survival in HER2-Positive Breast Cancer

Single Dose of Brachytherapy May Be an Effective Treatment for Localized Prostate Cancer

Two Migration Proteins Boost Predictive Value of Pancreatic Cancer Biomarker

11-Year Follow-up of Adjuvant Trastuzumab in the HERA Trial

Study Finds Sharp Rise in Colon and Rectal Cancers in Young Adults

Feasibility of Patient Reporting of Adverse Events in Cancer Clinical Trials

Clofarabine-Based Consolidation in Younger Patients With Acute Myeloid Leukemia in First Remission

Pembrolizumab vs Chemotherapy in Second-Line Treatment of Advanced Urothelial Carcinoma

Poor Diet During Adolescence/Early Adulthood and Risk for Premenopausal Breast Cancer

FDA Approves Telotristat Ethyl for Carcinoid Syndrome Diarrhea

Patients With Cancer History More Likely to Change Prescriptions to Save Money

ASCO Quality Care 2017: Mental Health Conditions Contribute to Care-Related Costs, Hospital Visits in Breast and Prostate Cancers

ASCO Quality Care 2017: Study Examines Cancer Center Websites’ Information on Breast Cancer Treatment, Outcomes

ASCO Quality Care 2017: In-House Specialty Pharmacy at Cancer Center Improves Quality of Care, Reduces Medical Errors

Patient-Reported Outcomes for Assessing Symptom Burden in Patients Receiving Oral Anticancer Therapy

Effect of Adjuvant Chemoradiotherapy in Resected Locally Advanced Head and Neck Cancer

Cholesterol-Lowering Medication Use and Breast Cancer Outcome in the BIG 1-98 Trial

Researchers Use Cardiomyocytes to Create Index of Cardiotoxicity of Tyrosine Kinase Inhibitors

Development of a Voided Urine Assay for Detecting Prostate Cancer Noninvasively

Are Most Patients With Metastatic Melanoma Eligible for Immunotherapy Clinical Trials?

Preclinical Study of PI3K/mTOR Inhibitors in Uterine Leiomyosarcomas

Study Finds Cancer Mortality in Hispanics Varies Among Ethnic Groups

Myeloablative vs Reduced-Intensity HCT for Acute Myeloid Leukemia and Myelodysplastic Syndromes

FDA Approves Lenalidomide as Maintenance Therapy for Patients With Multiple Myeloma Following Autologous Stem Cell Transplant

Payers Weigh the Implications of Multigene Testing Coverage

Chinese Trial Adds Utidelone to Capecitabine in Heavily Pretreated Patients With Metastatic Breast Cancer

Southern Surgical Association Annual Meeting: Isolated Limb Infusion for Extremity Sarcoma May Preserve Limbs

More Patients With Early-Stage Breast Cancer May Be Able to Avoid Chemotherapy in the Future

ASCO-SITC Clinical Immuno-Oncology Symposium: Utility of Biomarkers for Predicting Colorectal Cancer Survival Depends on Tumor Location

ASCO-SITC Clinical Immuno-Oncology Symposium: Response to Cancer Immunotherapy May Depend on Gut Bacteria

Olaparib Meets Primary Endpoint in OlympiAD Trial in BRCA-Mutated Metastatic Breast Cancer

2017 GU Cancers Symposium: Atezolizumab Plus Bevacizumab Shows Potential in Metastatic Renal Cell Carcinoma

2017 GU Cancers Symposium: Updated Efficacy and Tolerability of Durvalumab in Locally Advanced or Metastatic Urothelial Carcinoma

Optimal Time to Assess Response After Chemoradiotherapy in Anal Squamous Cell Carcinoma

Variable Transparency of Industry-Sponsored Oncology Financial Assistance Programs

Sarcopenia in Esophageal Cancer Represents a Significant Risk to Survival

Palliative Radiation Therapy for Bone Metastases: Update of an ASTRO Evidence-Based Guideline

Health-Related Quality of Life in Pivotal Trial of Adjuvant Ipilimumab in Stage III Melanoma

Study Finds Suboptimal Use of Adjuvant Endocrine Therapy in Breast Cancer

Protein Component of the Epstein-Barr Virus May Promote the Development of Cancer

Early Biomarker Algorithm May Predict Graft-vs-Host Disease Occurrence

Effect of Scalp-Cooling Device on Hair Loss in Women Receiving Chemotherapy for Breast Cancer

Study Finds Mutations in Myelodysplastic Syndrome Linked to Poorer Outcome After Stem Cell Transplantation

Never Smokers Account for Increased Proportion of Non–Small Cell Lung Cancer Cases

Gefitinib or Erlotinib vs Chemotherapy in EGFR-Mutant Advanced Non–Small Cell Lung Cancer

Combination of Alisertib and HSV1716 Shows Antitumor Activity in Malignant Peripheral Nerve Sheath Tumor and Neuroblastoma Models

Disease Symptoms Are the Most Frequent Indicators of Recurrence in Patients With Stage II Melanoma

Intermittent Vismodegib Regimens in Patients With Multiple Basal Cell Carcinomas

Managing Patients With Low-Risk Neutropenic Fever at Cleveland Clinic Taussig Cancer Institute

Adding Bevacizumab to Perioperative Chemotherapy in Esophagogastric Adenocarcinoma

Genetic Testing and Counseling Among Women With Newly Diagnosed Breast Cancer

Clinical Trial Explores Ability of Genetic Test to Guide Surgical Management of Thyroid Cancer

Patients With Breast Cancer With Dense Breast Tissue More Likely to Develop Contralateral Disease

2017 GU Cancers Symposium: In Advanced Kidney Cancer, Antibiotic Use Lowers Efficacy of Immunotherapy

2017 GU Cancers Symposium: Some Patients With Renal Cell Carcinoma Experience Long-Term Tumor Control Even After Stopping Immunotherapy Early

2017 GU Cancers Symposium: Blood Test Uncovers Potential New Treatment Targets in Advanced Prostate Cancer

ASCP/CAP/AMP/ASCO Guideline on Molecular Biomarkers for Evaluation of Colorectal Cancer

Comparison of Sentinel Lymph Node Biopsy vs Lymphadenectomy in Endometrial Cancer Staging

Researchers Identify ‘Synthetic Essentiality’ as Novel Approach for Locating Cancer Therapy Targets

Most Patients Undergoing Elective Colorectal Surgery Receive Inadequate Bowel Preparation to Prevent Postoperative Complications

Adding Buparlisib to Paclitaxel in Platinum-Pretreated Squamous Cell Carcinoma of the Head and Neck

Zoledronic Acid Every 12 Weeks vs Every 4 Weeks in Women With Breast Cancer and Bone Metastases

Does Obesity Pose Risk for Transformation of Monoclonal Gammopathy of Undetermined Significance to Myeloma?

Cancer Survivors Find Online and Telephone Communication With Health-Care Professionals Beneficial

Children, Parents Overreport Leukemia Treatment Adherence

Residual Cancer Burden, Breast Cancer Phenotype, and Long-Term Prognosis After Neoadjuvant Chemotherapy

Italian Trial Adds Bevacizumab to Cisplatin/Etoposide in Extensive-Disease Small Cell Lung Cancer

Adding Idelalisib to Bendamustine/Rituximab in Relapsed or Refractory Chronic Lymphocytic Leukemia

ASCP/CAP/AMP/ASCO Clinical Practice Guideline Focuses on Molecular Biomarker Testing for Patients With Colorectal Cancer

Women of Indigenous Communities Prefer Self-Screening for Cervical Cancer

Intentional Weight Loss in Postmenopausal Women May Be Linked to Reduced Endometrial Cancer Risk

Patient Coaching and End-of-Life Discussions in Advanced Cancer

Low Prostate Cancer–Specific Mortality in Men With Benign Initial Transrectal Ultrasound–Guided Biopsy Sets

Nivolumab in Metastatic Urothelial Carcinoma After Platinum Therapy

Nearly Half of Patients Treated for Early-Stage Breast Cancer Report at Least One Severe Side Effect

FDA Accepts Two sBLAs for Pembrolizumab in Locally Advanced or Metastatic Urothelial Cancer

Increased Risk of Cardiac Events With High Heart Dose in High-Dose Thoracic Radiotherapy

Accelerated Partial-Breast vs Whole-Breast Irradiation After Breast-Conserving Surgery

Adding Antiandrogen Therapy to Radiation Therapy in Recurrent Prostate Cancer

ECCO 2017: Pembrolizumab Shows Activity in Mucosal Melanoma in Multiple KEYNOTE Studies

Potential Suboptimal Use of Guideline-Endorsed Genomic Testing in Non–Small Cell Lung and Colorectal Cancers

Adjuvant Letrozole vs Anastrozole in Hormone Receptor–Positive Node-Positive Early Breast Cancer

FDA Approves Nivolumab in Locally Advanced or Metastatic Bladder Cancer

IASLC Statement on Philip Morris’ New Manifesto Highlights the Importance of Tobacco Control

ECCO 2017: Melanoma Death Rates Will Fall by 2050, but Number of Deaths Will Increase

ECCO 2017: Breath Test Might Help Detect Stomach and Esophageal Cancers

Intermittent Sunitinib Appears Feasible in Previously Untreated Metastatic Renal Cell Carcinoma

Phase III Trial Finds First-Line Ceritinib Improves PFS vs Platinum-Based Chemotherapy in ALK-Rearranged NSCLC

Postmenopausal Normal-Weight Women With Poor Metabolic Health May Have Higher Risk for Colorectal Cancer

ASH/AACR/AACI/ASTRO/ASPHO/Lungevity Foundation Statement on Administration's Executive Order

Immunotherapy 2.0 Named Advance of the Year in ASCO's Report

Benefits of Multiparametric Magnetic Resonance Imaging in Clinically Significant Prostate Cancer

ASCO Clinical Practice Guideline on Management of Small Renal Masses

How Does Sublingual Fentanyl Measure Up Against Subcutaneous Morphine in Managing Cancer Pain?

Study Finds Addition of Adjuvant Capecitabine to Gemcitabine Improves Survival in Resected Pancreatic Cancer

ECCO 2017: Some Patients With Early-Stage Breast Cancer May Benefit More From Breast-Conserving Therapy Than Mastectomy

ECCO 2017: Low Cause-Specific Mortality in Women Over 50 Treated for Ductal Carcinoma in Situ

High Financial Burden for CML Patients Enrolled in Medicare Part D Receiving Targeted Oral Therapy

Trends in Cancer Mortality in the United States and U.S. Counties From 1980 to 2014

Small-Intestine GIST Treated Surgically Associated With Better Prognosis in Younger Patients

Diagnosis and Management of AML in Adults: 2017 European LeukemiaNet Recommendations From an International Expert Panel

Health-Related Quality of Life After Cancer Diagnosis in Adolescents/Young Adults

Predicting Acute Cardiac Events in Patients With Breast Cancer Receiving Radiotherapy

Three Genetic Alterations Identified in Non–Down Syndrome Pediatric Acute Megakaryoblastic Leukemia

ECCO 2017: Twice-Daily Radiation Therapy May Reduce Mortality in Head and Neck Cancer

Venetoclax Studied in Relapsed or Refractory Non-Hodgkin Lymphoma

New Molecular-Based Prognostic Model for Glioblastoma in Temozolomide Era

SWOG Launches National Immunotherapy Clinical Trial for Rare Cancers

Low Loss of Residual Lifetime for Patients With DLBCL in Remission Who Were Event-Free 24 Months After Treatment

Potential Surrogate for All-Cause Mortality Risk in Localized Unfavorable-Risk Prostate Cancer

Survivorship Symposium 2017: Almost Half of Partners and Caregivers of Young Breast Cancer Survivors Experience Long-Lasting Anxiety

Predicting Outcomes in Older Patients With Cancer

Survivorship Symposium 2017: Physical and Psychological Factors Contribute to Decreased Physical Activity in 75% of Patients With Cancer

Survivorship Symposium 2017: Younger Survivors of Thyroid Cancer Face Increased Risk of Hypertension, Heart Disease, and Osteoporosis

2017 GI Cancers Symposium: Less Than Half of Recommended Adults Screened for Lynch Syndrome

2017 GI Cancers Symposium: Nivolumab Demonstrated Efficacy and Improved Survival in Patients With Previously Treated Advanced Gastric Cancer

Risk Factors for Estrogen Receptor–Positive and –Negative Breast Cancer

Novel Antibody May Reduce Debilitating Symptoms in Patients With Advanced Colorectal Cancer

Precision Medicine Analysis of 203 Pediatric Brain Tumors May Advance Diagnosis and Treatment

‘Collateral Lethality’ May Offer New Therapeutic Approach for Cancers of the Pancreas, Stomach, and Colon

Higher Intake of Grilled/Barbecued and Smoked Meat Linked to Reduced Survival After Breast Cancer

Similar Survival With Surgery and Chemoradiotherapy in HPV-Negative Oropharyngeal Squamous Cell Cancer

FDA Approves Ibrutinib in Relapsed/Refractory Marginal Zone Lymphoma

FDA Officially Establishes the Oncology Center of Excellence, Names Richard Pazdur, MD, as Director

Institute for Clinical Immuno-Oncology White Paper Highlights the Challenges, Progress, and Priorities in Immunotherapy

Venetoclax Plus Rituximab Studied in Relapsed or Refractory Chronic Lymphocytic Leukemia

177Lu-Dotatate Improves Progression-Free Survival in Midgut Neuroendocrine Tumors

Validation of the Five-Tiered Gleason Grade Grouping System in Patients With Prostate Cancer

Tucatinib Shows Clinical Benefit in Phase I Trial in HER2-Positive Breast Cancer

Pembrolizumab Studied in Locally Advanced or Metastatic Urothelial Cancer

What Influences a Woman’s Decision to Stop Chemopreventive Therapy for Breast Cancer?

2017 GI Cancers Symposium: Watch-and-Wait Approach for Rectal Cancer Appears an Option for More Patients

2017 GI Cancers Symposium: Physical Activity May Be Linked to Longer Survival in Advanced Colorectal Cancer

2017 GI Cancers Symposium: PET Scans Can Inform and Improve Treatment for Patients With Esophageal Cancer

Most Federal Exchange Plans Under Affordable Care Act Do Not Contain NCI-Designated Cancer Center

Lower Locoregional Failure but Increased Toxicity With Addition of Cetuximab to Chemoradiotherapy for Anal Carcinoma

Is Mirvetuximab Soravtansine Active in Platinum-Resistant Ovarian Cancer?

Clonal Hematopoiesis of Indeterminate Potential at Time of ASCT May Be Linked to Adverse Outcomes in Lymphoma

Identification and Characterization of HPV-Independent Cervical Cancers

Prostate Cancer Treatment Rates Drop, Reflecting Change in Screening Recommendations

Fear of Diagnostic Low-Dose Radiation Exposure May Be Overstated, Experts Assert

FDA Approves Morphine Sulfate Extended-Release Tablets Formulated With Abuse-Deterrent Properties

FDA Accepts sBLA and Grants Priority Review for Atezolizumab in Locally Advanced or Metastatic Urothelial Carcinoma

Potential Biomarker of Recurrent Venous Thromboembolism in Cancer Patients Receiving Anticoagulant Therapy

ASCO Releases Principles for Patient-Centered Health-Care Reform

Has the Affordable Care Act Reduced Socioeconomic Disparities in Cancer Screening?

No Increased Risk of Skeletal Events in Patients With Bone Metastases Taking Zoledronic Acid

Case Report of Regression of Glioblastoma After Chimeric Antigen Receptor T-Cell Therapy

Ofatumumab vs Rituximab in Salvage Therapy for Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Effect of Sorafenib in Patients With Advanced Hepatocellular Carcinoma May Depend on Hepatitis Status

Does Adding Bortezomib to Lenalidomide/Dexamethasone Improve Outcomes in Patients With Newly Diagnosed Myeloma?

NCI-Designated Cancer Centers Issue Statement in Support of New CDC Recommendations on HPV Vaccination

Patients With Non–Small Cell Lung Cancer May Benefit From Delayed Adjuvant Chemotherapy

Older Patients With Lung Cancer Face Significant Treatment Burden

TCGA Study of Esophageal Cancers Finds Features That Aid in Their Classification

Disappointing Efficacy of Chemotherapy Guided by Ki67 Level After Neoadjuvant AI Therapy for Breast Cancer

Survival Benefit Reported With Adjuvant Chemotherapy After Nephroureterectomy for Urothelial Carcinoma

Results of International Cross-Sectional Survey Reveal Gaps in Primary and Secondary Skin Cancer Prevention, Perceptions, and Knowledge

Cancer Death Rate Has Dropped 25% Since 1991 Peak, According to American Cancer Society Report

How Common Is Cognitive Impairment After Chemotherapy in Breast Cancer Survivors?

ASCO Clinical Practice Guideline Update: Integration of Palliative Care Into Standard Oncology Care

ACCC 2016 Survey Finds Cancer Drug Costs Remain the Most Critical Challenge to Care

Receptor Tyrosine Kinase AXL May Mediate Nuclear Translocation of EGFR

Diagnostic Laparoscopy May Predict Result of Primary Cytoreductive Surgery in Suspected Advanced Ovarian Cancer

No Improvement in Event-Free Survival Reported With More Extensive or Serial Resections in Wild-Type GIST

Benefit of Early Integrated Palliative Care in Patients With Newly Diagnosed Incurable Cancer

Endometrial Cancer Mutations May Be Detectable in Uterine Lavage Fluid Before Cancer Is Diagnosed

FDA Grants Priority Review for the sNDA for Regorafenib in the Second-Line Systemic Treatment of Liver Cancer

Germline Cancer Susceptibility Mutations in Early-Onset Colorectal Cancer

Contralateral Prophylactic Mastectomy Decisions in a Population-Based Sample of Patients With Early-Stage Breast Cancer

Preclinical Study Potentially Explains Vulnerability of Young Patients With Cancer to Treatment Toxicities

Comparison of Scales for Assessing Cisplatin-Related Ototoxicity in Children

Genome-Based Model for Adjusting Radiotherapy Dose Shows Promise

Myeloid-Derived Suppressor Cells May Enable Tumor Cells to Circumvent Immune Attack, Improving Immunotherapy

Vascular-Targeted Photodynamic Therapy Shows Promise in Low-Risk Prostate Cancer

Is Adding Onartuzumab to Erlotinib of Benefit in Advanced Non–Small Cell Lung Cancer?

Customer Response to Personal Genomic Testing for Cancer Risk

FDA Permits Marketing of New Tissue Expander for Women Undergoing Breast Reconstruction Following Mastectomy

Improved Survival With Higher Tumor-Infiltrating Lymphocyte Values in Advanced HER2-Positive Breast Cancer

Atezolizumab Shows Activity in First-Line Treatment of Cisplatin-Ineligible Patients With Advanced Urothelial Carcinoma

ESMO Asia 2016: Study Validates Set of Six Adaptable Prognosis Prediction Models for Patients With Cancer in Palliative Care Settings

ESMO Asia 2016: Depressed Patients May Be Less Responsive to Chemotherapy

Atezolizumab Improves Survival vs Docetaxel in Previously Treated Non–Small Cell Lung Cancer

Circulating Tumor DNA May Serve as a Prognostic Marker in Pancreatic Cancer

FDA Approves Rucaparib and Companion Genetic Test in Advanced Deleterious BRCA-Mutated Ovarian Cancer

ESMO Asia 2016: Asian Patients With Head and Neck Squamous Cell Carcinoma Live Longer With Immunotherapy Than Overall Population

ESMO Asia 2016: First Data Presented on Rare Sarcomas in Asian Patients

T-Cell Transfer Therapy Targets Mutant KRAS in Metastatic Colorectal Cancer

ASCO Makes No Changes to 2014 Recommendations for Sentinel Lymph Node Biopsy in Early-Stage Breast Cancer

Effectiveness of Electroacupuncture for Sleep Disturbances in Patients With Breast Cancer and Hot Flashes

Addition of Adjuvant Chemotherapy to Chemoradiotherapy Achieves Best Survival Results in Locally Advanced Nasopharyngeal Carcinoma

Effect of Inpatient Palliative Care on Quality of Life After Stem Cell Transplant

Study Finds Regorafenib Improves Survival in Patients With Hepatocelluar Carcinoma Progressing on Sorafenib

ESMO Asia 2016: Almost 20% of Swedish Breast Cancer Patients Fail to Complete Prescribed Endocrine Therapy

Monica M. Bertagnolli, MD, Elected ASCO President for 2018–2019 Term

WCLC 2016: First-Line Ceritinib Reduces Risk of Disease Progression in ALK-Positive NSCLC vs Chemotherapy

WCLC 2016: Icotinib May Improve Progression-Free Survival vs Whole-Brain Irradiation in Patients With NSCLC With Brain Metastases

WCLC 2016: New Lung Cancer Tumor Staging Manual to Shape Clinical Treatment

First-in-Class Rovalpituzumab Tesirine Active in Recurrent Small Cell Lung Cancer

ASCO Clinical Practice Guideline on Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers

ESMO Asia 2016: Patients in India Wait an Average of 4 Months Before Seeking a Cancer Diagnosis

WCLC 2016: Phase II LUME-Meso Trial on Oral Nintedanib in Mesothelioma Demonstrates Meaningful Clinical Benefit

Promising Activity Seen With First-Line Nivolumab Plus Ipilimumab in Advanced Non–Small Cell Lung Cancer

Osimertinib Improves Progression-Free Survival vs Platinum/Pemetrexed in EGFR T790M–Positive NSCLC

ASCO CEO Dr. Clifford Hudis Commends President Obama, Vice President Biden, and Congress During 21st Century Cures Act Signing Ceremony

Rucaparib Appears Effective in Relapsed Platinum-Sensitive High-Grade Ovarian Carcinoma

Phase III Trial Shows Improved Progression-Free Survival With Fulvestrant vs Anastrozole in Hormone Receptor–Positive Advanced Breast Cancer

SABCS 2016: IBM Watson for Oncology Platform Shows High Degree of Concordance With Physician Recommendations

SABCS 2016: Aromatase Inhibitors Were Associated With Reduced Endothelial Function in Postmenopausal Breast Cancer Patients

SABCS 2016: Neoadjuvant Abemaciclib Treatment May Benefit Patients With Early-Stage Hormone Receptor–Positive, HER2-Negative Breast Cancer

SABCS 2016: Scalp-Cooling Device Safe and Effective in Reducing Chemotherapy-Induced Alopecia in Women With Breast Cancer

SABCS 2016: Women Experiencing Menopausal Symptoms Less Likely to Adhere to Medication in IBIS-1 Trial

SABCS 2016: BELLE-3 Trial of Buparlisib Plus Endocrine Therapy Meets Primary Endpoint of Progression-Free Survival in Breast Cancer Patients

SABCS 2016: Adding Veliparib to Chemotherapy Improved Response Rates Among Patients With BRCA-Mutant Breast Cancer

SABCS 2016: Radiation Therapy May Increase Complications in Breast Cancer Patients Receiving Implants

SABCS 2016: Adding Ibandronate to Hormone Therapy Did Not Improve Outcomes for Postmenopausal Breast Cancer Patients

SABCS 2016: No Added Benefit With Aromatase Inhibitor as Part of Presurgical Therapy for Hormone Receptor–Positive, HER2-Positive Breast Cancer

SABCS 2016: Axillary Lymph Node Dissection Might Be Avoidable for Certain Early-Stage Breast Cancer Patients Receiving Neoadjuvant Chemotherapy

Sodium Thiosulfate Seems to Protect Against Cisplatin-Related Hearing Loss in Children With Cancer

SABCS 2016: Extended Letrozole Therapy Showed Limited Benefit in Postmenopausal Women With Early-Stage, Hormone Receptor–Positive Breast Cancer

SABCS 2016: Adding Everolimus to Fulvestrant Improved Outcomes for Postmenopausal Patients With Hormone Receptor–Positive Breast Cancer

SABCS 2016: Genomic Sequencing of Treatment-Resistant Metastatic Breast Cancer Reveals Clinically Relevant Genetic Alterations

ASCO Praises Congress for Accelerating the Development and Delivery of Cancer Treatment With 21st Century Cures Act

Successful Retreatment With Cisplatin-Based Therapy Reported in Men Relapsing After Adjuvant Carboplatin for Stage I Seminoma

No Significant Benefit of Perindopril or Bisoprolol in Reducing Trastuzumab-Associated Cardiac Remodeling in HER2-Positive Breast Cancer

Equivalent Response Rates With Trastuzumab or Trastuzumab Biosimilar Plus Taxane in HER2-Positive Metastatic Breast Cancer

ASH 2016: Additions to Standard Multiple Myeloma Therapy Do Not Appear to Yield Additional Benefit

ASH 2016: Children With Down Syndrome and ALL Fare as Well as Other Children Treated on ALL Consortium Protocols

ASH 2016: Ibrutinib and TGR-1202 Combination Yields Encouraging Results in Patients With Relapsed Forms of Leukemia or Lymphoma

ASH 2016: New Data Shed Light on Potential Advantages of Pacritinib for Patients With Myelofibrosis

ASH 2016: IKZF1 Gene Mutations Found to Increase Hereditary Risk for Acute Lymphocytic Leukemia in Children

ASH 2016: Ibrutinib Found Helpful in Treating Graft-vs-Host Disease After Stem Cell Transplant

Study Finds No Predictive Value of ERCC1 Marker for Outcomes With Nonplatinum vs Platinum Therapies in NSCLC

ASCO Endorses ASTRO Guideline on Radiation Therapy for Glioblastoma

ASH 2016: KTE-C19 in Patients With Chemorefractory Primary Mediastinal B-Cell Lymphoma and Transformed Follicular Lymphoma

ASH 2016: Interim Analysis Shows Adding Lenalidomide Maintenance Therapy to Chemoimmunotherapy Prolongs Progression-Free Survival in High-Risk CLL

ASH 2016: CD19-Targeting CAR T-Cell Immunotherapy Yields High Response Rates in Treatment-Resistant CLL

Does Androgen-Deprivation Therapy Increase the Risk for Dementia in Patients With Prostate Cancer?

Activating NOTCH1 Mutations Identify Poor-Prognostic Subgroup With Adenoid Cystic Carcinoma

ASH 2016: Patients With CML and Stable Molecular Responses May Be Able to Safely Decrease the Dose of Their Tyrosine Kinase Inhibitor

ASH 2016: Cessation of Tyrosine Kinase Inhibitor Treatment in Chronic Myeloid Leukemia Patients With Deep Molecular Response

ASH 2016: Phase I Trial of Vadastuximab Talirine in Combination With 7+3 Induction Therapy for Patients With AML

ASH 2016: Study Shows Patients Traditionally Ineligible for Studies May Benefit From Trial Participation

ASH 2016: Biomarker May Predict Which Patients Previously Treated for Cancer Will Develop Highly Fatal Form of Leukemia

ASH 2016: New CAR T-Cell Therapy Holds Promise for Children and Young Adults With Hard-to-Treat ALL in Phase I Trial

ASH 2016: New Chemotherapy Delivery Method Improves Survival After Bone Marrow Transplant in Older Patients With AML

ASH 2016: Preventative Antibiotics Could Prevent Clostridium difficile Among Stem Cell Transplant Recipients

Psychotropic and Opioid Medication Use in Older Patients With Breast Cancer Across the Care Trajectory

Having a Child With Cancer May Adversely Affect Parents’ Income and Employment

Assessment of Therapeutic Response by Intrinsic Subtype for HER2-Positive Breast Tumors

Alcohol Intake Associated With Modest Increase in Risk of Melanoma

FDA Grants sBLA to Pembrolizumab for the Treatment of Relapsed or Refractory Classical Hodgkin Lymphoma

EORTC-NCI-AACR 2016: ‘Remarkable Antitumor Activity’ in Phase I Studies of PDGFRα and KIT Mutation Inhibitors

EORTC-NCI-AACR 2016: Liquid Biopsies Identify Molecular Alterations Driving GI Cancer Drug Resistance in Nearly 80% of Patients

High Frequency and Poor Outcome of Philadelphia Chromosome–Like ALL Reported in Adults

Increased Morbidity and Mortality in HCT Survivors vs Other Cancer Survivors

RSNA 2016: Large Study Finds No Evidence for Age-Based Mammography Cutoff

Outreach to Patients With Cirrhosis Doubles Early Screening Rates for Liver Cancer

Association of Extent of Surgeon-Assessed Resection on Outcome in High-Risk Neuroblastoma

Obesity/Overweight and Lower Activity Level May Increase Risk of Taxane-Induced Neuropathy in Women With Invasive Breast Cancer

High-Dose Chemotherapy and Autologous PBSCT for Relapsed Metastatic Germ Cell Tumors

FDA Grants Priority Review to Pembrolizumab for New Indication in Microsatellite Instability–High Cancer

FDA Grants Full Approval and Label Update for Ponatinib in CML and ALL

ASCO Releases Criteria for High-Quality Clinical Pathways in Oncology

Projected Financial Burden of Targeted Therapies for Chronic Lymphocytic Leukemia

Can Mindfulness-Based Cognitive Therapy Reduce Distress in Patients With Advanced Prostate Cancer?

Study Finds Serum DNA Methylation an Early Marker of Response and Survival in Metastatic Breast Cancer

NCCN Imaging Appropriate Use Criteria Published for 15 Additional Guidelines

AMA Statement on Opening Day Court Case Against Anthem-Cigna Deal

Study Shows Modestly Reduced Breast Cancer Recurrence Risk With Increased Protein Intake Independent of Tumor Insulin Receptor Status

Link Between Previous Treatment for Depression and Increased Risk of Receiving Nonguideline Treatment in Early-Stage Breast Cancer

Postinduction Minimal Residual Disease Predicts Outcome and Benefit From ASCT in NPM1-Mutant AML

Study Finds EXITS Gene Mutations May Contribute to Cancer Sex Bias

Factors Predictive of Outcomes With Dabrafenib/Trametinib in Metastatic BRAF-Mutant Melanoma

Pooled Analysis of Outcome With Nivolumab Alone or With Ipilimumab in Advanced Mucosal or Cutaneous Melanoma

CAP/ASCP/ASCO Guideline on HER2 Testing and Clinical Decision-Making in Gastroesophageal Adenocarcinoma

Safety Profile of Nivolumab Monotherapy in Advanced Melanoma

Center for Leukemia and Lymphoma Research at UNMC Renamed Dr. James O. Armitage Center for Leukemia and Lymphoma Research

FDA Approves Daratumumab in Combination With Lenalidomide/Dexamethasone or Bortezomib/Dexamethasone in Multiple Myeloma

Association of T-Cell CD62L Expression and Molecular Response to Tyrosine Kinase Inhibitor Therapy in Early Chronic-Phase CML

Activation of WNT5A May Drive Glioblastoma Stem Cell Differentiation and Invasive Growth

Weight Loss May Help Prevent Multiple Myeloma

Phase III Trial Shows Ado-Trastuzumab Emtansine Noninferior to Trastuzumab/Taxane in HER2-Positive Breast Cancer

Updated ASTRO Guideline Expands Pool of Suitable Candidates for Accelerated Partial-Breast Irradiation

Novel Urine Test May Predict High-Risk Cervical Cancer

Fulminant, Fatal Myocarditis Reported in Two Patients After Starting Combined Immune Checkpoint Blockade Treatment

Cabozantinib Shows Activity in Advanced RET-Rearranged NSCLC

SITC 2016: Interim Phase I/II Data Show Encouraging Clinical Benefit for Lirilumab in Combination With Nivolumab in Head and Neck Cancer

SITC 2016: Phase I/II Data Combining Urelumab With Nivolumab Suggest Increased Antitumor Effect in Patients With Melanoma

Phase III Trial Shows Improved PFS With Addition of Palbociclib to Letrozole in ER-Positive, HER2-Negative Breast Cancer

‘Exceptional Response’ to First-Line Vismodegib Reported in Patient With Unresectable/Multifocal Adult Medulloblastoma

New Study Links Obesity, Starting at Adolescence, to Endometrial Cancer Among Women Not Using Hormone Therapy

SITC Publishes First Kidney Cancer Treatment Guideline to Focus on Immunotherapy

Factors in Clonal Evolution of Chemotherapy-Resistant Urothelial Carcinoma Identified

Study Finds Cabozantinib of Clinical Benefit vs Sunitinib in Advanced Kidney Cancer

Study Finds Cabozantinib Alone or With Erlotinib Improves Outcome in EGFR Wild-Type NSCLC

New ALK Inhibitor, Brigatinib, Active in ALK-Rearranged Non–Small Cell Lung Cancer

Study Describes Genetic Model of Pro-B ALL

SITC 2016: Immune Checkpoint Inhibitors Shrink Tumors in Some Patients With Metastatic Bladder Cancer

NAALADL2 Marker for Aggressive Prostate Cancer May Also Serve as a Drug Target

Blocking ADAM17 Protein May Help to Circumvent Resistance to Cetuximab in Bowel Cancer

Does Telotristat Ethyl Reduce the Frequency of Bowel Movements in Patients With Metastatic NETs and Carcinoid Syndrome?

Improved Outcomes Reported With Retinoic Acid and Arsenic Trioxide vs Retinoic Acid and Chemotherapy in APL

NCCN Challenges Medical Community to ‘Just Bag It’ to Eradicate Deadly Medical Error

FDA Approves Nivolumab for the Treatment of Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck

No Benefit Reported With Addition of Palifosfamide to Doxorubicin in Metastatic Soft-Tissue Sarcoma

Do Cancer Survivors Use Medications for Anxiety and Depression at a Higher Rate Than Those Without Cancer?

Enrollment Completed for Phase III ECHELON-2 Clinical Trial Evaluating Front-Line Brentuximab Vedotin in Mature T-Cell Lymphoma

Low Vitamin D Levels May Be Linked to Increased Risk of Bladder Cancer

Lower Risk of All-Cause Mortality in Multiple Myeloma Reported With Treatment at Higher-Volume Facilities

No Advantage to Adding Seribantumab to Paclitaxel in Platinum-Resistant/Refractory Ovarian Cancer, but Subgroup May Benefit

Gold Nanoparticle Radiopharmaceuticals for the Selective Treatment of Telomerase-Positive Tumors

1 in 6 Women Diagnosed With Breast Cancer Have a Symptom Other Than a Lump

Adult Survivors of Childhood Cancers Report Long-Term Health Issues

Concerns About Safety of Generic Oncology Drugs Made in Developing Countries

Second Opinions From Urologists for Prostate Cancer: Do They Make a Difference?

Improved Outcome Reported With Local Consolidative Therapy in Oligometastatic NSCLC Without Progression After First-Line Systemic Therapy

Higher Complete Pathologic Regression Rate With Neoadjuvant Docetaxel- vs Epirubicin-Based Triplets in Gastric/Gastroesophageal Junction Cancer

Gut Microbes Linked to Immunotherapy Response in Patients With Melanoma

Mammography Outcomes Improve When Physicians Compare Prior Screenings

Researchers Reveal Genomic Landscape of Core-Binding Factor Acute Myeloid Leukemia

Multiple Genetic Mutational Signatures Associated With Smoking

7 Substances Added to HHS 14th Report on Carcinogens

Distress Screening in Oncology Leads to Better Doctor-Patient Relationships and Improved Outcomes

Personalized Risk Assessment Tool for Lung Cancer in Never, Light, and Heavy Smokers

New Data Suggest Changes Needed to Guidelines for Determining Prognosis in Patients With Thyroid Cancer

ASCO Launches COME HOME Initiative to Give Oncology Practices Concrete Path Toward Alternative Payment System

Genetic Testing May Be Beneficial in Identifying Patients With Breast Cancer at High Risk for Venous Thromboembolism

Study Raises Concerns About Timely Follow-up to Positive Mammogram for the Uninsured

Daratumumab Produces Sustained Remission in a Patient With Refractory Extranodal NK Cell–T-Cell Lymphoma

Ribociclib Granted FDA Priority Review for First-Line Treatment of Hormone Receptor–Positive/HER2-Negative Advanced Breast Cancer

Phase III SOLO-2 Trial Shows Significant Progression-Free Survival Benefit From Olaparib Treatment in BRCA-Mutated Metastatic Ovarian Cancer

Study Shows International Trends in Anal Cancer Incidence Rates

Adulthood BMI Increases Leading to Obesity Seem to Be Linked to an Increased Risk of Fatal Prostate Cancer

French Trial Shows Addition of Androgen Maintenance Improves Survival in Elderly Patients With Acute Myeloid Leukemia

Breast Cancer Hormonal Therapy Persistence and Adherence Better in Black, Hispanic, and White Women With vs Without Medicare D Prescription Subsidies

Effect of Patient Age on Outcomes in Breast Reconstruction

Japanese Trial Finds High Levels of Estrogen in Lung Tissue May Be Related to Synchronous Multiple Lung Adenocarcinoma in Postmenopausal Women

Poorer Outcomes Reported After ASCT in Double-Hit and Double-Expressor Relapsed and Refractory Lymphomas

Sexual Pain Experienced by Women After Cancer Is Common and May Be Ignored

Link Between Molecular Mechanisms in Prostate Cancer and Ewing Sarcoma Found

Potential Link Between Androgen-Deprivation Therapy for Prostate Cancer and Risk for Dementia

Proportion of Cancer Deaths From Smoking Varies Across States and Is Highest in the South

Prolonged Length of Stays, Readmissions, and Discharge to Care Facilities Among Postoperative Patients With Advanced Cancer

Presence of Oral Bacterium in Esophageal Cancer Samples Associated With Shorter Patient Survival

24-Gene Predictor of Response to Postoperative Radiotherapy in Prostate Cancer

Is Regorafenib Active in Advanced Nonadipocytic Soft-Tissue Sarcoma?

New Blood Test for Colorectal Cancer Recurrence Is Twice as Sensitive as CEA Test

Proton Pump Inhibitors Seem to Reduce the Efficacy of Capecitabine in Advanced Gastroesophageal Cancer

Effect of Isolated Peritoneal and Nonperitoneal Metastasis and Metastatic Sites on Survival in Patients With Colorectal Cancer

FDA Approves Pembrolizumab as First-Line Treatment for PD-L1–Positive Non–Small Cell Lung Cancer

Osimertinib Shows Activity in Pretreated EGFR Thr790Met–Positive Advanced NSCLC

CDC Recommends Only Two HPV Shots for Younger Adolescents

KEYNOTE-045 Studying Pembrolizumab in Advanced Bladder Cancer Meets Primary Endpoint and Stops Early

CancerLinQ Platform Hits Milestone of Having More Than 1 Million Patient Records in System

Psychoeducational Intervention Reduces Fear of Melanoma Recurrence in Patients With High-Risk Melanoma

ESMO 2016: Longer Interval Between Preoperative Chemoradiotherapy and Surgery Urged in Locally Advanced Rectal Cancer

ESMO 2016: Dabrafenib/Trametinib/Panitumumab Improves Efficacy in BRAF Mutation–Positive Metastatic Colorectal Cancer

ESMO 2016: Vemurafenib Shows Clinical Benefit in Diverse BRAF V600–Mutated Tumors

Association of PD-L1 Expression and Response to Pembrolizumab in Advanced Melanoma

Study Finds Nivolumab Improves Survival vs Standard Therapy in Recurrent Squamous Cell Carcinoma of the Head and Neck

Investigational Immunotherapy Appears Safe and Somewhat Active in Advanced Melanoma

ESMO 2016: Clinical Benefit Demonstrated With Everolimus and Pasireotide LAR Alone or in Combination in Advanced Lung and Thymic Carcinoids

ESMO 2016: Meta-analysis Confirms Superiority of Concomitant Over Induction Chemotherapy in Nonmetastatic Head and Neck Cancer

ESMO 2016: Pooled Analysis Shows PD-L1 Expression as a Biomarker for Nivolumab Plus Ipilimumab Response in Advanced Melanoma

Study Finds Adjuvant Sunitinib Improves Disease-Free Survival in High-Risk Renal Cell Carcinoma After Nephrectomy

Mammography-Detected Small Breast Cancers May Represent Overdiagnosis, With Survival Gains Reflecting Improved Systemic Therapy

FDA Grants Accelerated Approval to Olaratumab for Treatment of Advanced Soft-Tissue Sarcoma

Atezolizumab Approved for the Treatment of Metastatic NSCLC That Has Progressed During or After Platinum-Containing Therapy

FDA Modifies the Indication of Erlotinib in Non–Small Cell Lung Cancer to Patients With Specific EGFR Mutations

Dutch Study Shows High Prevalence of Early Endocrine Disorders in Survivors of Childhood Brain Tumors

Study Finds PFS Benefit, but No Overall Survival Benefit, for Ipilimumab in Metastatic Castration-Resistant Prostate Cancer

Adding Pembrolizumab to Carboplatin/Pemetrexed Seems to Improve Response in Advanced Nonsquamous NSCLC

Does Adding Daratumumab to Lenalidomide/Dexamethasone Improve Outcomes in Previously Treated Multiple Myeloma?

ESMO 2016: First-Line Pembrolizumab Plus Chemotherapy Significantly Improves Outcomes in Advanced NSCLC

ESMO 2016: Nivolumab Maintains Function and Reduces Symptoms in Relapsed Metastatic Head and Neck Cancer

Is Nivolumab Active in Recurrent Advanced Urothelial Carcinoma?

Intensity-Modulated vs 3D Conformal External-Beam Radiation Therapy in Locally Advanced Non–Small Cell Lung Cancer

Adjuvant Ipilimumab Prolongs Survival in High-Risk Stage III Melanoma, Phase III Study Reports

Study Finds Increased Risk for Non-Hodgkin Lymphoma in HIV-Infected Patients

Vice President Biden Delivers Cancer Moonshot Report, Announces Public and Private Sector Actions to Advance Cancer Moonshot Goals

Genetic Markers Associated With Pathologic Complete Response to Neoadjuvant Therapy Identified in HER2-Positive Breast Cancer

Impact of Severe Fatigue on Treatment Outcome and Social Reintegration in Hodgkin Lymphoma

First-Line Pembrolizumab Improves Survival vs Platinum-Based Chemotherapy in Advanced PD-L1–Positive NSCLC

HHS Finalizes MACRA Rule, ASCO Applauds Focus on High-Quality Patient-Centered Care

ESMO 2016: Researchers Identify Factors Associated With End-of-Life Chemotherapy Use

ESMO 2016: Antitumor Activity Demonstrated With Lurbinectedin in Patients With Metastatic Breast Cancer and BRCA Mutations

Massachusetts Health Insurance Expansion Associated With Increased Resection and Reduced Emergent Resection for Colorectal Cancer

Study Finds Niraparib Maintenance Improves Progression-Free Survival in Platinum-Sensitive Recurrent Ovarian Cancer

ESMO 2016: Fulvestrant Improves Progression-Free Survival in Advanced Breast Cancer

ESMO 2016: Nintedanib Improves Progression-Free Survival but Not Overall Survival in Metastatic Colorectal Cancer

ESMO 2016: Immunotherapy Shows Promising Results in First- and Second-Line Treatment of Metastatic Bladder Cancer in Two Trials

ESMO 2016: Cabozantinib Improves Progression-Free Survival in Metastatic Renal Cell Carcinoma

Long-Term Effects of Finasteride in Patients From the Prostate Cancer Prevention Trial

Characteristics of HPV-Driven Nonoropharyngeal Squamous Cell Carcinomas of the Head and Neck

First-Line Ribociclib Prolongs Progression-Free Survival in Hormone Receptor–Positive, HER2-Negative Advanced Breast Cancer

Delayed Initiation of Tyrosine Kinase Inhibitors Reported in Medicare Patients With Chronic Myeloid Leukemia

Does Adding IMA901 Vaccine to Sunitinib Improve Survival in Advanced Renal Cell Carcinoma?

ESMO 2016: Ceritinib Provides Longer Progression-Free Survival Than Chemotherapy in Phase III Trial of ALK-Rearranged Lung Cancer Treatment

ESMO 2016: Significant Survival Gains With Atezolizumab vs Docetaxel for Non–Small Cell Lung Cancer

ESMO 2016: Longer Disease-Free Survival in Phase III Trial of Sunitinib as Adjuvant Treatment for Kidney Cancer

ESMO 2016: Significant Survival Gains From Neoadjuvant Chemotherapy for High-Risk Soft-Tissue Sarcoma

Women With Breast Cancer Report Primary Care Physician Involvement in Care and Participation in Decision-Making

Study Indicates Safety of Stopping Imatinib in CML With Undetectable Minimal Residual Disease for at Least 2 Years

ESMO 2016: Pembrolizumab a New Option for First-Line Treatment of Patients With Advanced Lung Cancer and High PD-L1 Expression

ESMO 2016: Niraparib Significantly Improves Outcomes in Platinum-Sensitive Recurrent Ovarian Cancer

ESMO 2016: Ipilimumab as Adjuvant Therapy Improves Overall Survival in High-Risk Stage III Melanoma

ESMO 2016: Ribociclib Improves Progression-Free Survival in Advanced Breast Cancer

Adding Health Navigation Assistance to Community Helpline Connected More People to Cancer Control Measures

Lack of Androgen Receptor Protein May Contribute to Racial Disparities in Triple-Negative Breast Cancer Outcomes

Is Second-Line Ramucirumab of Benefit in Advanced Hepatocellular Carcinoma?

Good CNS Response to Alectinib Reported in Previously Treated ALK-Positive Non–Small Cell Lung Cancer

African American Cancer Survivors More Likely to Experience Lasting Debt Related to Cancer and Its Treatment

Affordable Care Act Increased Access to Cancer Care and Clinical Trial Participation Among Hispanics

Modified Staging System for Pancreatic Neuroendocrine Tumors

Improved Failure-Free Survival Reported With Addition of Induction Chemotherapy to Concurrent Chemoradiotherapy in Nasopharyngeal Carcinoma

Meta-analysis Shows Association of Minimal Residual Disease–Negative Status With Improved Survival in Multiple Myeloma

Particular HPV Strain Linked to Improved Prognosis for Oropharyngeal Cancer

Development and Validation of a Quality Assurance Score for Robot-Assisted Radical Cystectomy

Some Gains Reported in Enrollment Disparity in National Lung Cancer Trials

Temozolomide vs Radiotherapy in High-Risk Low-Grade Glioma

FDA Grants Breakthrough Therapy Designation for First-Line Treatment of ALK-Positive NSCLC

COA Releases 2016 Community Oncology Practice Impact Report

Study Finds TP53 and MDM2 Alterations Linked to Cisplatin Resistance in Advanced Germ Cell Tumors

Does Adding Adjuvant Bevacizumab to Capecitabine Benefit Patients With Colorectal Cancer?

Study Finds Pneumonitis Associated With Anti–PD-1/PD-L1 Antibody Treatment

FDA Approves Osimertinib Blood-Based T790M Companion Diagnostic Test

Phase II Trial Shows Benefit of Ibrutinib in Relapsed/Refractory CLL With 17p Deletion

Study Reports No Association Between Vasectomy and Prostate Cancer Incidence or Mortality

ASTRO 2016: Intervention Closes Racial Gap and Improves Treatment Rates for Early-Stage Lung Cancer

ASTRO 2016: Stereotactic Radiosurgery Decreases Rate of Postoperative Local Recurrence for Brain Metastases

Ratio of Certain Immune Cells in the Blood to Tumor Burden Correlated With Outcome for Melanoma Patients Treated With Pembrolizumab

Combining AM0010 and Pembrolizumab Produced Antitumor Activity in Patients With Advanced Solid Tumors

ASTRO 2016: Extremely Hypofractionated Radiation Therapy Shows Promising Toxicity Results for Intermediate-Risk Prostate Cancer

NCCN Publishes New Clinical Practice Guidelines for Myeloproliferative Neoplasms

Study Finds Statin Use Associated With Reduced Mortality in Multiple Myeloma

Is Pembrolizumab Active Against Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma?

ASTRO 2016: Postoperative Stereotactic Radiosurgery: New Standard of Care for Patients With Resected Brain Metastases?

ASTRO 2016: Reduced Radiation Boost Volume Recommended for Average-Risk Pediatric Medulloblastoma, but Craniospinal Axis Dose Remains Unchanged

ASTRO 2016: Hypofractionated Radiation Therapy May Halve Treatment Time for Lung Cancer Patients With Poor Performance Status

ASTRO 2016: SBRT Offers Patients With Prostate Cancer High Disease Control and Low Toxicity in Fewer Treatments

Patient-Reported Outcomes After Active Monitoring, Surgery, or Radiotherapy in PSA-Detected Localized Prostate Cancer

ASCO/ASTRO/SSO Develop Focused Guideline Update on Postmastectomy Radiotherapy

ASTRO 2016: Intermediate-Risk Prostate Cancer May Be Well Controlled With Brachytherapy Alone

ASTRO 2016: Radiation Boost Reduces Local Tumor Recurrence for Patients With DCIS Following WBRT

ASTRO 2016: Advances in Radiation Therapy Have Improved Survival Rates for Patients With Early-Stage Lung Cancer

ASTRO 2016: Three Novel Intrinsic Subtypes of Prostate Cancer Identified

ASTRO 2016: Hypofractionated Radiation Therapy Can Reduce Treatment Time With Comparable Quality of Life for Patients With Prostate Cancer

ASTRO 2016: Unmet Need for Radiation Therapy Found Among Nearly Half of Eligible Cancer Patients in Nine Developing Countries

ASTRO 2016: Widespread Adoption of SBRT Has Improved Survival Rates for Elderly Patients With Early-Stage Lung Cancer

ASTRO 2016: Cervical and Endometrial Cancer Patients Report Fewer Side Effects and Better Quality of Life With IMRT

Improved Event-Free Survival With Addition of Rituximab to Chemotherapy in B-Lineage Adult ALL

Effect of G-CSF Prophylaxis With Chemotherapy for Breast Cancer on Neutropenia-Related Hospitalization

Does Colonoscopy Screening in Older Adults Prevent Colorectal Cancer?

Addition of CHK1 Inhibitor Radiosensitizes Head and Neck Cancers to Paclitaxel-Based Chemoradiotherapy

Blood Biomarkers in Abiraterone- or Enzalutamide-Resistant Prostate Cancer Tumor Cells 

10-Year Risk of Invasive Breast Cancer After Diagnosis of Atypical Ductal Hyperplasia by Needle Biopsy

Analysis Indicates Survival Advantage With Neoadjuvant Therapy in Resectable Pancreatic Cancer

Nonwhite Organ Transplant Recipients Also at Heightened Risk for Skin Cancer

High-Calcium, Low-Lactose Diet May Reduce Risk of Ovarian Cancer in African American Women

Comparison of Second-Line Treatments in Advanced Pancreatic Cancer After Gemcitabine-Based Chemotherapy

Survival Benefit Reported With Maintenance Olaparib in Platinum-Sensitive Recurrent Serous Ovarian Cancer With BRCA Mutation

Enhanced Survival With Implantable Scaffolds That Capture Metastatic Breast Cancer Cells in Vivo

Early Studies Examine Response of CML-Initiating Cells to Ezh2 Inhibition

Decisional Regret After Initial Treatment Decisions Among Parents of Children With Cancer

Conflicting Interpretations of Genetic Findings on Multiplex Testing in Clinical Practice

‘Encouraging Survival Outcomes’ Reported With Combined Nivolumab and Ipilimumab in Advanced Melanoma

Overall Survival With Everolimus in Advanced Pancreatic Neuroendocrine Tumors in the RADIANT-3 Trial

CDC Finds Cancer Death Rates Among Children and Adolescents Declined by 20%, With Brain Cancer Topping Leukemia as Leading Cause of Death

Adolescent Girls With Leukemia May Not Be Screened for Pregnancy Before Beginning Chemotherapy

Good Outcome Reported With Unrelated-Donor Cord Blood Transplantation in Patients With Minimal Residual Disease

Vice President Biden Announces New Steps to Improve Clinical Trials Essential to Advancing the Cancer Moonshot

Joint Presence of Metabolic Syndrome and Obesity Seems to Be Associated With Poorer Survival in Early-Stage Colorectal Cancer

Study Suggests Role of Bilateral Oophorectomy in Preventing Premenopausal Breast Cancer in BRCA2- but Not BRCA1-Mutation Carriers

American Association for Cancer Research Releases 2016 Cancer Progress Report

Decline in Circulating Tumor Cell Count and Treatment Outcome in Advanced Prostate Cancer

Everolimus Plus Bevacizumab Shows Activity in Advanced Non–Clear Cell Renal Cell Carcinoma

FDA Modifies Dosage Regimen for Nivolumab

Combined FISH and IHC Identifies Patients With NSCLC With Rare ALK Fusions That Respond to Crizotinib

Similar 10-Year Survival Reported With Active Monitoring, Surgery, or Radiotherapy for PSA-Detected Localized Prostate Cancer

NCI Colorectal Cancer Risk Assessment Tool Estimates Current Risk of Advanced Neoplasia

New American Cancer Society Report Reveals Gaps in Pediatric Cancer Research

Preclinical Study Finds Tamoxifen Resistance Linked to High Estrogen Levels in Utero

PSA Failure Seems to Be Linked to Poorer Survival in Men With Unfavorable-Risk Prostate Cancer and No/Minimal Comorbidity

Shorter Survival Reported With Neoadjuvant Chemotherapy vs Primary Reductive Surgery in Stage IIIC Ovarian Cancer

Chinese Journal of Cancer Extends Deadline for Submission of Most Important Questions in Cancer Research and Clinical Oncology

Palliative Care 2016: Attitudes of ASTRO Members Toward Palliative and Supportive Care in the United States

Palliative Care 2016: Rehospitalization of Patients With Advanced Cancer in the Year After Diagnosis

Improved Quality of Life Reported With Carfilzomib, Lenalidomide, and Dexamethasone in Relapsed Multiple Myeloma

Autopsy Data Suggest No Increase in Differentiated Thyroid Cancer Over Past Few Decades

Durable Responses Reported With Avelumab in Chemotherapy-Refractory Metastatic Merkel Cell Carcinoma

Little Benefit Reported With WBRT in NSCLC Patients With Brain Metastases Unsuitable for Resection or Stereotactic Radiotherapy

Study Finds HIV Infection Linked to Reduced Survival Among Women With Cervical Cancer in Botswana

Palliative Care 2016: Usage of Oregon’s Death With Dignity Act

Early FDG-PET and Volumetric Analysis May Be Best Predictors of Benefit in Ewing Sarcoma

Palliative Care 2016: Inpatient Palliative Care in Patients Hospitalized for HSCT

Palliative Care 2016: Perception of Curability in Patients With Advanced Cancer Receiving Palliative Care

Is Weekly Vinblastine Active in Chemotherapy-Naive Children With Progressive Low-Grade Glioma?

FDA Warns of Risks Associated With the Use of Tests Marketed as ‘Ovarian Screening’

ASCO and AACI Collaborate on Initiative to Reduce Administrative and Regulatory Burden in Cancer Clinical Trials

Electronic Health Record Data May Help Identify Older Patients at Highest Risk of Early Death From Chemotherapy for Diffuse Large B-Cell Lymphoma

Study Suggests Benefit of Adjuvant Radiation Therapy but Not Chemotherapy in Some Patients With Merkel Cell Carcinoma

Study Examines Global Trends in Ovarian Cancer Mortality Rates

FDA Grants Priority Review to Pembrolizumab for First-Line Treatment of Advanced NSCLC

Is Extramedullary Disease at Diagnosis Prognostic in Adult Acute Myeloid Leukemia?

DNA Methylation Assay May Improve Diagnosis of Cancer of an Unknown Primary

Is Obesity a Prognostic Factor for Improved Survival in Metastatic Renal Cell Carcinoma?

ASCO Applauds Bold Recommendations From Cancer Moonshot Blue Ribbon Panel

FDA Approves Blinatumomab for Use in Pediatric Patients With Ph-Negative Relapsed or Refractory B-Cell Precursor ALL

Posttreatment Problems Surveyed in African American Breast Cancer Survivors

Study Finds Minimal Residual Disease Assessment Improves Prediction of Outcome in CLL Responders

Does Intensified Postoperative Chemotherapy for High-Grade Osteosarcoma Benefit Poor Responders to Preoperative Therapy?

Continuation of Docetaxel May Improve Survival in Metastatic Castration-Resistant Prostate Cancer

Palliative Care 2016: 'Mystery Shopper' Study Finds Barriers to Accessing Palliative Care Services at Major Cancer Centers

Palliative Care 2016: Family Caregivers for Patients With Advanced Cancer Often Experience High Levels of Anxiety, Depression

Palliative Care 2016: Early Palliative Care Improves Coping, Quality of Life for Patients With Incurable Cancers

Palliative Care 2016: Cancer Caregivers Experience Unique Burdens Compared With Those Caring for Patients With Other Conditions

Discrepancies Between Current ASCO-CAP Guidelines on HER2 Amplification Testing and Designations in BCIRG Trials

Early-Stage Prostate Cancer Incidence Rates Decline, Distant-Stage Disease Rates Unchanged in 2013

Better Overall Survival Reported With FOLFIRI Plus Cetuximab vs Plus Bevacizumab in RAS Wild-Type Metastatic Colorectal Cancer

PSA-Based Computational Model Predicts Time to Relapse After Prostate Cancer Surgery

Patients With Cancer May Be at Heightened Risk of Injuries During Diagnostic Process

Study Finds Gemcitabine/Cisplatin Improved Outcome vs Fluorouracil/Cisplatin in Recurrent or Metastatic Nasopharyngeal Carcinoma

Autologous Stem Cell Transplant May Age Immune Cells as Much as 30 Years

Accumulation of Metabolite Fumarate May Be Linked to Hereditary Leiomyomatosis and Renal Cell Cancer

HSD3B1 Allele May Be Associated With Resistance to Androgen-Deprivation Therapy and Poorer Outcome in Prostate Cancer

Tumor-Infiltrating Lymphocytes and Crohn’s-Like Lymphoid Reaction May Be Prognostic Indicators for Colorectal Cancer

Higher Baseline Metabolic Tumor Volume May Predict Poorer Outcome in Patients With High Tumor Burden Follicular Lymphoma

Gene Overexpression Scoring System May Accurately Predict Patient Response to Cancer Treatments

FDA Approves Ofatumumab in Combination With Fludarabine and Cyclophosphamide for Relapsed CLL

Predicted Burden of Cervical Cancer With vs Without Effective Screening in Baltic, Central, and Eastern European Countries

Incidence of PD-1 Inhibitor–Related Pneumonitis in Advanced NSCLC, Renal Cell Carcinoma, and Melanoma

Retinoic Acid May Suppress Colorectal Cancer Development

Artificial Intelligence May Expedite Breast Cancer Risk Prediction

Outpatient Bloodstream Infections Costly for Pediatric Stem Cell Transplant and Cancer Patients

Psychosocial Adjustment, Breast Cancer–Specific Distress in Adolescent Girls From BRCA1/2-Positive and Breast Cancer Families

Adding Daratumumab to Bortezomib/Dexamethasone Improves Progression-Free Survival in Relapsed/Refractory Multiple Myeloma

Researchers Question Process for Reviewing Coverage of 'Off-Label' Cancer Drug Use

Novel MRI Technique Distinguishes Healthy Prostate Tissue From Cancer Using Zinc

Epigenetic Dysregulation of MicroRNA-34A Identified in TP53-Related Cancer Risk

Study Finds Chemotherapy May Be Avoidable in Women With Early Breast Cancer at High Clinical but Low Genomic Risk on 70-Gene Signature Assay

Study Finds Genetic Risk Variants in Half of Patients With Sarcoma

Extended Active Surveillance Prior to Systemic Therapy May Be Safe in Some Patients With Metastatic Renal Cell Carcinoma

Does Lymph Node Metastasis Have a Negative Prognostic Impact in Patients With NSCLC and M1a Disease?

FDA Accepts New Drug Application, Grants Priority Review of Rucaparib for the Treatment of Advanced BRCA-Mutant Ovarian Cancer

Melanoma MicroRNA Trafficking May Control Tumor Primary Niche Formation

Study Finds More Nodes Should Be Examined to Rule Out Node-Negative Disease in Papillary Thyroid Cancer

Influence of Patients’ Side-Effect Expectations on Outcome of Endocrine Treatment for Breast Cancer

Meta-analysis Identifies New Genetic Variants for Barrett’s Esophagus and Esophageal Adenocarcinoma

Overall Survival With Bevacizumab/Capecitabine Noninferior vs Bevacizumab/Paclitaxel in HER2-Negative Breast Cancer

Study Finds Effect of Combined Hormone Replacement Therapy on Breast Cancer Risk Likely to Have Been Underestimated

Increased Uveal Melanoma Risk Linked to Pigmentation Genes That Dictate Eye Color

Breast Density and Risk Factors May Be Useful for Tailoring Breast Cancer Screening for Older Women

New Preclinical Study Shows Esophageal Cancers Driven by 'Marginal Gain' Rather Than Speed

ASCO and SGO Release Clinical Practice Guideline on Neoadjuvant Therapy for Newly Diagnosed Advanced Ovarian Cancer

Racial/Ethnic Disparities in Genomic Sequencing

Parents May be More Likely to Support HPV Vaccine Requirements for School Entry If States Include Opt-Out Provisions

Study Links F12 and STC2 Genes to Breast Cancer Survival

Psychological Impact of Genetic Testing to Be Explored in Subset of NCI-MATCH Trial Patients

Study Finds Computers Surpass Pathologists in Predicting Lung Cancer Type, Severity

Bone Marrow–Derived Stem Cells May Offer Blood Transplant Recipients Better Quality of Life

Study Finds ‘Bursts’ of Chromosome Changes Fuel Breast Cancer Tumor Growth

Pulmonary Complications in Adult Survivors of Childhood Cancer

Preclinical Study Finds Etoposide May Damage Developing Ovaries of Female Fetuses

New Study Suggests Integrating Multiple Types of Protein Biomarkers Increases Accuracy of Early Breast Cancer Detection

Leptomeningeal Metastases More Common in NSCLC With EGFR Mutations, May Be Responsive to Tyrosine Kinase Inhibitors

Immune Analysis of On-Treatment Longitudinal Biopsies Predicts Response to Melanoma Immunotherapy

Report Tracks Cancer Trends by Race/Ethnicity in Los Angeles County for 37 Years

Study Confirms Benefit of Cobimetinib Plus Vemurafenib in Advanced BRAF V600–Mutant Melanoma

Combining Radium-223 With Other Therapies May Be of Benefit in Metastatic Castration-Resistant Prostate Cancer

New SSO, ASTRO, and ASCO Joint DCIS Consensus Guideline Could Curb Unnecessary Breast Surgery and Reduce Health System Costs

Needle Biopsies for Noninvasive Breast Cancer: Routine Analysis Wastes Millions

Obesity on the Rise in Adults With a History of Cancer

Study Finds United States Ranks First in Health-Care Spending, but Cancer Outcomes Do Not Reflect the Investment

Study Finds Venetoclax Monotherapy Safe and Clinically Active in AML

Metabolic Imaging as a Method to Assess Treatment Response to Cytotoxic and Cytostatic Agents

Study Identifies Novel Treatment Resistance Mechanism in BRAF-Mutant Melanoma

CA-125 Tests and CT Scans Still Routinely Used for Surveillance in Ovarian Cancer, Yet Benefit Remains Unproved

FDA Grants Orphan Drug Designation to CD4CAR for the Treatment of Peripheral T-Cell Lymphoma

New American Cancer Society Cancer Action Network Report Shows States Are Making Progress Implementing Policies to Reduce Toll of Cancer

New Study Shows Breast Tumors May Evolve in Response to Hormone Therapy

Similar Functional Outcomes Reported With Robot-Assisted Laparoscopic and Open Radical Retropubic Prostatectomy

FDA Approves Extended-Release Granisetron Injection for the Prevention of Chemotherapy-Induced Nausea and Vomiting

Higher Exposure to Radical Local Treatment Linked to Lower Mortality in Men With Very High-Risk Prostate Cancer

Study Explores How Breast Cancers Resist Chemotherapy

Hypofractionated Radiotherapy Not Inferior to Conventional Radiotherapy in Low-Risk Prostate Cancer

Nivolumab Did Not Meet Primary Endpoint of Progression-Free Survival in NSCLC in CheckMate-026 Trial

Insurance Status Impacts Survival, According to Two New Studies

Chinese Journal of Cancer Collecting 150 Most Important Questions in Cancer Research and Clinical Oncology

ASCO and SGO Issue New Guideline on Ovarian Cancer Treatment

Study Shows Women Who Received Cancer Screening Invitation Letters Are More Likely to Have a Pap Test

FDA Approves Pembrolizumab for Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma After Platinum-Containing Chemotherapy

Reference Laboratory Identifies Change in Pattern of Breast Cancer HER2 Fluorescence in Situ Hybridization Results

Ribociclib Receives FDA Breakthrough Therapy Designation for Treatment of Hormone Receptor–Positive, HER2-Negative Advanced Breast Cancer

Androgen-Deprivation Therapy May Increase Mortality in African American Men With Favorable-Risk Prostate Cancer

Phase III Trial Finds No Survival Benefit of Adding Ipilimumab to Etoposide/Platinum in Extensive-Stage SCLC

Study Finds Low Engagement in Internet-Based Research in Underrepresented Population

High-Intensity Local Treatment May Improve Survival in Patients With Metastatic Urothelial Carcinoma of the Bladder

Metabolic Gene-Expression Profile May Identify Kidney Cancer Patients Unlikely to Benefit From Nivolumab

Vemurafenib Active in BRAF V600E–Positive Papillary Thyroid Cancer Refractory to Radioactive Iodine

Genetic Characteristics of Recurrent and Metastatic Head and Neck Cancers

New Study Finds Increase in Imaging After Thyroid Cancer Treatment Identifies Recurrence but May Not Improve Survival

African American Women More Likely to Choose Autologous Breast Reconstruction Over Implant-Based Reconstruction

Identification of Genetic Variants Associated With Extranodal Natural Killer T-Cell Lymphoma

Potential Link Between Obesity and Cardiotoxicity From Anthracyclines Alone or With Trastuzumab for Breast Cancer

Increased Obesity Rates Reported in Adults With a History of Cancer

AAPM 2016: Somatic Mutations and PET-Based Radiomic Features in Non–Small Cell Lung Cancer

Social Media Engagement May Be Linked to More Satisfaction With Breast Cancer Treatment Decisions

Recommendations for Surveillance of Premature Ovarian Insufficiency in Female Survivors of CAYA Cancers

High Cumulative Burden of Cardiovascular Morbidity in Young Survivors of Hodgkin Lymphoma

Neoadjuvant Veliparib/Carboplatin and Neratinib ‘Graduate’ From Adaptive Randomization I-SPY 2 Trial in Early Breast Cancer

ASCO Releases Clinical Practice Guideline on Management of Chronic Pain in Survivors of Adult Cancers

Insurance, Distance to Care Can Be Barriers to Breast Reconstruction

Sampling Method Used for New Breast Cancer Tests May Lead to Underestimation of Risk

Combining Ipilimumab With Radiotherapy or Electrochemotherapy May Prolong Survival in Patients With Advanced Melanoma

Potential Link Between Pembrolizumab Use and Demyelinating Polyradiculoneuropathy Reported in Two Cases of Advanced Melanoma

Association Between Germline Mutation in VSIG10L and Barrett's Esophagus/Esophageal Cancer

Sociodemographic and Clinical Predictors of Switching to Active Treatment From Observational Management in Low-Risk Prostate Cancer

No Improvement in Outcome Reported With Longer Wait Between Radiochemotherapy and Surgery in Rectal Cancer

Potential Increased Risk of Serous/Serous-like Endometrial Carcinoma After RRSO in Women With BRCA1 Mutation

Study Evaluates Chronic Graft-vs-Host Disease Burden and Complications in Patients Receiving Bone Marrow Transplants

Effect of Radiosurgery Alone vs Radiosurgery Plus WBRT on Cognitive Function in Patients With Brain Metastases

Pathway Defects in Acquired Resistance to PD-1 Inhibition in Melanoma Identified

Ceritinib Shows Overall and Intracranial Activity in Advanced NSCLC Previously Treated With Crizotinib and Chemotherapy

USPSTF Issues Final Recommendation Statement on Screening for Skin Cancer

Delirium Frequent and Underdiagnosed Among Advanced Cancer Patients Presenting to an Emergency Department

Is Nivolumab Active in Classical Hodgkin Lymphoma After Failure of Autologous SCT and Brentuximab Vedotin?

European Study Finds Chromosome 1q Gain Linked to Poorer Outcome in Wilms Tumor Treated With Preoperative Chemotherapy

Poorer Outcome in Favorable-Histology Wilms Tumor Associated With Chromosome 1q Gain Reported in U.S. Study

FDA Grants Breakthrough Therapy Designation for Daratumumab in Combination With Standard of Care for Multiple Myeloma

Gene-Expression Signature Assay Identifies High-Risk Stage II Colon Cancer

Patients With Low-Risk Prostate Cancer on Active Surveillance Experience Good Quality of Life

Olanzapine Combination Reduces Nausea and Vomiting in Patients Receiving Highly Emetogenic Chemotherapy

Some Adolescent Survivors of Childhood Cancer May Benefit From More Comprehensive Mental Health Screening

Ipilimumab Appears Active in Relapsed Hematologic Cancer After Allogeneic HSCT

Study Finds New Whole-Exome Sequencing Test Accurately Identifies Actionable Mutations

In Vitro Fertilization Not Associated With Increased Risk of Breast Cancer in Dutch Study

POLE Mutations in Colorectal Cancer May Identify Patients With a Better Prognosis

New ASTRO Clinical Practice Statement Updates Treatment Standard for Rectal Cancer

Pap Smear Screenings May Help Prevent Cervical Cancer in Women Over 65

Hematologic Oncologists Surveyed on Quality Measures of End-of-Life Care and Barriers to Such Care

Meta-analysis Indicates Similar Outcomes With Neoadjuvant Endocrine vs Chemotherapy in Estrogen Receptor–Positive Breast Cancer

Endocrine Abnormalities Increase Over Time in Aging Survivors of Childhood Cancer

Discovery of Fragment Length of Circulating Tumor DNA Might Increase Liquid Biopsy Sensitivity

Can Self-Administered Acupressure Reduce Fatigue in Breast Cancer Survivors?

Five-Year Survival Data: Brentuximab Vedotin May Be Curative in Some Patients With Hodgkin Lymphoma

Study Finds Wide Variation in Breast Density Assessments Among Radiologists

American Cancer Society Endorses HPV Vaccine Recommendations From CDC ACIP

Stress and Adverse Life Events Unlikely to Cause Breast Cancer

Swiss Study Examines Cost-Effectiveness of Nivolumab vs Docetaxel in Advanced Nonsquamous NSCLC

No Survival Benefit for Cabozantinib Reported in Previously Treated Metastatic Castration-Resistant Prostate Cancer

CNS-IPI for CNS Relapse in Diffuse Large B-Cell Lymphoma

Comparison of Chemotherapy Regimens in Metastatic Esophageal and Gastroesophageal Junction Adenocarcinoma

Analysis Indicates Continued Risk of Relapse Independent of Treatment Modality in Limited-Stage DLBCL

Patient-Oncologist Difference of Opinion About Advanced Cancer Prognosis Is Common, Study Shows

Early Evidence of Anti–PD-1 Activity in Enzalutamide-Resistant Prostate Cancer

Early Results Find Pembrolizumab Active in Classical Hodgkin Lymphoma After Brentuximab Vedotin Failure

Preclinical Study Shows Target of Trastuzumab, Receptor Protein ErbB2, Needed for Coronary Vasculature Patterning

PET/MRI: A One-Stop Imaging Test to Detect Prostate Cancer?

Weight Loss in Overweight and Obese People May Lower Levels of Certain Proteins Linked to Cancer

Juno Therapeutics to Resume JCAR015 Phase II ROCKET Trial After FDA Clinical Hold

Opportunistic Salpingectomy for Ovarian Cancer Prevention Adopted Without Adverse Surgical Outcomes

Immune Cell Infiltrates May Portend Better Prognosis Across Several Tumor Types

Long-Term Benefit of Lenalidomide/Dexamethasone Reported in High-Risk Smoldering Multiple Myeloma

Internationally Renowned Geneticist, Alfred George Knudson, MD, PhD, Dies

New Analysis Evaluates Predictors of Persistent Pain After Breast Cancer Surgery

Heart Failure After First Heart Attack Associated With Increased Risk of Cancer

Obesity Linked to Increased Risk of Multiple Myeloma Mortality in African Americans

Better 10-Year Survival Reported With Breast-Conserving Surgery and Radiotherapy vs Mastectomy in Early Breast Cancer

Plasma vs Tissue Genotyping and Outcomes With Osimertinib in Advanced Non–Small Cell Lung Cancer

Shorter Remission Telomere Length Associated With Prolonged Neutropenia After Pediatric AML Treatment

Despite Increasing Global Legalization of Physician-Assisted Suicide, Use Remains Rare

Survey Asks Women Whom They Trust Most When Selecting Breast Cancer Surgery and Reviews Postsurgical Satisfaction

Study Finds Incidence of Mutations in DNA-Repair Genes Significantly Higher in Men With Metastatic Prostate Cancer

FDA Approves First HPV Test for Use With SurePath Preservative Fluid

FDA Advances Precision Medicine Initiative by Issuing Draft Guidances on Next-Generation Sequencing–Based Tests

ESMO Releases New Consensus Guidelines on the Management of Metastatic Colorectal Cancer

First-Line Nivolumab Monotherapy Active in Advanced NSCLC

First-Line Nivolumab Active in Combination With Platinum-Based Doublets in Advanced NSCLC

When Combined With Targeted Therapy, Cytoreductive Nephrectomy May Improve Survival in Metastatic RCC

World GI 2016: Anti–Interleukin-1 Alpha Antibody MABp1 Improves Outcomes Significantly Over Placebo in Advanced Colorectal Cancer

World GI 2016: Chemoradiotherapy After Surgery for Gastric Cancer Shows Similar Outcomes to Postoperative Chemotherapy

World GI 2016: Anti–PD-L1 Immunotherapy Combined With MEK Inhibition Shows Response in Microsatellite-Stable Metastatic Colorectal Cancer

World GI 2016: Phase III RESORCE Study Data Show Regorafenib Improves Overall Survival in Previously Treated Patients With Unresectable Liver Cancer

Mixed Results With Hypofractionated vs Conventional Radiotherapy for Localized Prostate Cancer

Updated Outcomes and Impact of Age in FIRST Trial in Multiple Myeloma

Impact of Systemic Inflammation on Quality of Life in Advanced Cancer

Fentanyl Nasal Spray Now Available at a Dose of 300 μg for Treatment of Breakthrough Cancer Pain

HOX Gene Expression in Ovarian Cancer Offers Novel Prognostic Significance

Relapse of Leukemia After Bone Marrow Transplantation: Cytomegalovirus Infection Has No Protective Effect

Routine Prophylactic vs Deferred Radiotherapy for Procedure-Tract Metastases in Malignant Pleural Mesothelioma

Higher Prediagnostic Plasma Vitamin D Levels May Be Associated With Prolonged Survival in Pancreatic Cancer

Comparison of Chemotherapy Regimens After Negative Interim PET-CT in Advanced Hodgkin Lymphoma

Kaposi Sarcoma–Associated Herpesvirus Mimics Host Signal to Drive Cell Growth, Protein Production

Analysis of Cerebrospinal Fluid for D-2-Hydroxyglutarate May Detect Malignant Brain Tumors Nonsurgically

Improved Survival Reported With Prostate Radiation Therapy Plus Androgen-Deprivation Therapy in Metastatic Prostate Cancer

Factors Associated With Chemotherapy-Induced Peripheral Neuropathy in Older Patients

Study Finds Regorafenib Increases Progression-Free Survival in Advanced Gastric Cancer

Approximately 20% of Older Women With Early Breast Cancer Experience Some Form of Functional Decline After Treatment

Primary Care Visits Result in More Colorectal Cancer Screening, Better Follow-up

No Advantage With Cyclophosphamide/Methotrexate Maintenance in Hormone Receptor–Negative Early Breast Cancer, but Subgroup May Benefit

Tasquinimod Improves Radiographic PFS but Not OS in Metastatic Castration-Resistant Prostate Cancer

Study Finds Adding Olaratumab to Doxorubicin Improves Survival in Advanced Soft-Tissue Sarcoma

French Phase III Trial Shows No Benefit of Adding Zoledronate to Chemotherapy and Surgery in Osteosarcoma

Adding Obinutuzumab to Bendamustine Improves Progression-Free Survival in Rituximab-Refractory NHL

Influence of Microbiota of Breast Tissue on the Development of Cancers

Women With High-Grade Cervical Intraepithelial Neoplasia Have Long-Term Increased Risk for HPV-Related Anal, Vulvar, and Vaginal Cancers

NCCN Publishes New Patient Education Resources About Myelodysplastic Syndromes

At Cancer Moonshot Summit, Vice President Biden Announces New Actions to Accelerate Progress Against Cancer

Richard Pazdur, MD, Named Acting Director of the FDA Oncology Center of Excellence

FDA Approves Sofosbuvir/Velpatasvir for Treatment of Chronic Hepatitis C Virus Infection

ASCO Outlines Opposition to Medicare Part B Demo for Senate Finance Hearing

Study Finds Addition of High-Dose Cytarabine to Immunochemotherapy Before Transplant Improves Outcomes in Younger Patients With MCL

No Overall Advantage to Adding Pertuzumab to Chemotherapy in Platinum-Resistant Ovarian Cancer, but Subgroup May Benefit

Ipilimumab Combined With Antigen-Specific Cytotoxic T Lymphocytes May Be of Benefit in Metastatic Melanoma

CAP, IASLC, and AMP Seek Public Comments on Revised Lung Cancer Molecular Testing Guideline

Nivolumab Receives FDA Breakthrough Therapy Designation for Advanced/Metastatic Urothelial Carcinoma

Reduced-Intensity Transplantation With Haploidentical Related Donors vs HLA-Matched Sibling Donors in Patients With Lymphoma

Is Nivolumab Active in Recurrent Small Cell Lung Cancer?

Adherence to Cancer Prevention Guidelines on Diet and Physical Activity May Reduce Cancer Risk and Mortality

Nivolumab or Ipilimumab Treatment May Increase Risk of Developing Autoimmune Joint and Tissue Disease

Hypofractionated Radiation Found Equivalent to Conventionally Fractionated Regimen in Early-Stage Breast Cancer

Sequential Nivolumab/Ipilimumab Appears More Active Than Reverse Sequence in Advanced Melanoma

Dabrafenib Plus Trametinib Shows Activity in BRAF V600E–Mutant Metastatic NSCLC

CAR T-Cell Therapy Using Double Target Aimed at Solid Tumors in Preclinical Models

Influence of Age and Comorbidities on Rates of Colorectal Cancer Screening in the Elderly

USPSTF Issues New Recommendations for Colorectal Cancer Screening

Pembrolizumab Active for Untreated/Progressive Brain Metastases in Melanoma or NSCLC

Autologous Stem Cell Transplantation Offers Safe, Effective Option for Patients With HIV-Associated Lymphoma

Is Anti–PD-L1 Antibody Durvalumab Active in Advanced Urothelial Bladder Cancer?

Low-Dose CT Screening May Detect New Solid Nodules and Lung Cancer Probability

Final Results of METEOR Trial Show Cabozantinib Improves Overall Survival vs Everolimus in Advanced RCC

Patient Navigators Improve Comprehensive Cancer Center Screening Rates

Report Finds Families of Cancer Survivors Challenged by Intense, Episodic Caregiving Experiences

Genomic Classification and Outcome in Acute Myeloid Leukemia

Improved Quality of Life Reported With Nivolumab vs Everolimus in Advanced Renal Cell Carcinoma

SNMMI 2016: VASH Collimator Allows Three-Dimensional Imaging of the Breast With Less Radiation

Protein Could Help Identify Chronic Graft-vs-Host Disease

Neoadjuvant Chemotherapy May Render Advanced Ovarian Cancers Responsive to Immunotherapy

Japanese Trial Shows Improved Survival With Adjuvant S-1 vs Gemcitabine in Resected Pancreatic Cancer

SNMMI 2016: Pretargeted Radioimmunotherapy Eliminates Colorectal Cancer in Preclinical Studies

SNMMI 2016: PET/CT Imaging of Prostate Cancer With Specific Agent May Be an Accurate Prebiopsy/Preoperative Guide

SNMMI 2016: Personalized Kidney Dosimetry Optimizes Radiotherapy Dose in Patients With Neuroendocrine Tumors

Lifestyle Pattern May Be Associated With Cancer Risk in White Adults

Study Finds Inotuzumab Ozogamicin Improves Outcomes vs Standard Therapy in Relapsed/Refractory ALL

SNMMI 2016: A Blood-Based Multi-Transcript Test May Predict Success of Neuroendocrine Cancer Therapy

SNMMI 2016: FDG-PET Evaluates Immunotherapy for Non–Small Cell Lung Cancer

SNMMI 2016: CT-Based Lean Body Mass Calculations Improve Accuracy of PET for Patients With Cancer

Mindfulness-Based Stress-Reduction Program May Reduce Psychological and Physical Symptoms in Breast Cancer Survivors

Study Finds Pembrolizumab Active in Advanced Head and Neck Cancer

Many Family Physicians May Be Misinformed About Lung Cancer Screening

Adjuvant Chemotherapy in Early-Stage Non–Small Cell Lung Cancer Improves Overall Survival

Norwegian Study Shows Benefit of Aspirin as Secondary Prevention in Patients With Colorectal Cancer

Increased Risk for Cardiovascular Events Seen in Patients With CML Taking Tyrosine Kinase Inhibitors

ASCO 2016: Nivolumab Shows Promise in Refractory, Metastatic Anal Cancer

ASCO 2016: Hispanic and Black Young Adults With Cancer May Be More Likely to Die of Their Disease

ASCO Releases Clinical Practice Guideline on Metastatic Pancreatic Cancer

ASCO Releases Clinical Practice Guideline on Treatment of Locally Advanced, Unresectable Pancreatic Cancer

ASCO Releases Clinical Practice Guideline on Treatment of Potentially Curable Pancreatic Cancer

European Study Suggests No Benefit of GnRH in Preserving Ovarian Function and Fertility in Young Women With Lymphoma

Study Finds Poor Understanding of Illness in Patients With Advanced Cancer

ASCO 2016: Nivolumab Extends Survival for Patients With Advanced Renal Cell Carcinoma Treated Beyond Disease Progression

ASCO 2016: Cancer Diagnosed More Often in Patients With Primary Immunodeficiency Disease

Increased Risk of Gallbladder Cancer May Be Linked to Consuming Large Amounts of Sweetened Beverages

ASCO Announces New Award Honoring Visionary Leader Allen S. Lichter, MD, FASCO

Global Economic Crisis May Be Linked to Increased Cancer Mortality

ASCO 2016: Patients With Cancer With ACA Policies Swiftly Reach Out-of-Pocket Caps

Four-Biomarker Panel Identified for Chronic Graft-vs-Host Disease

ASCO 2016: Pembrolizumab Shows Significant Clinical Response in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma

Enzastaurin Fails to Improve Outcomes in Patients With High-Risk DLBCL in Remission After Chemotherapy

ASCO 2016: Significant Cost Differences Found Among Breast Cancer Chemotherapy Regimens

ASCO 2016: Early Detection, Detection of Smaller Cancers Among Benefits of a Primary Care–Based Skin Cancer Screening Program

Exercise Associated With Reduced Risk of Cardiovascular Events in Women With Nonmetastatic Breast Cancer

First-Line Fludarabine, Cyclophosphamide, and Rituximab vs Bendamustine/Rituximab in Advanced CLL

ASCO 2016: Nivolumab Immunotherapy Improves Survival, Quality of Life in Metastatic or Recurrent Head and Neck Cancer

ASCO 2016: CancerLinQ Extends Its Reach, Announces New Partnerships

ASCO 2016: ASCO Announces Milestones of TAPUR Study

ASCO 2016: Local Consolidative Therapy Improves Progression-Free Survival in Patients With Oligometastatic NSCLC vs Standard Chemotherapy

Investigational Drug Abemaciclib Shows Promising Activity Against Several Cancer Types in Early Study

Prognostic Impact of Recurrence Score and Estrogen Receptor Expression in Breast Cancer After 5 Years of Tamoxifen

Study Finds Apparent Benefit of Adding Fosbretabulin to Bevacizumab in Recurrent Ovarian, Tubal, or Peritoneal Carcinoma

ASCO 2016: Vast Differences Globally in Cancer Drug Retail Prices

ASCO 2016: Minority BRCA-Positive Breast Cancer Survivors Appear Less Likely to Receive Preventive Surgery

ASCO 2016: Many Younger Cancer Patients Receive Aggressive End-of-Life Care Despite ASCO’s Choosing Wisely Campaign

ASCO 2016: Study Finds Use of Mobile Web App Associated With Improved Outcomes in Lung Cancer

ASCO 2016: Novel Antibody Significantly Improves Survival in Patients With Advanced Gastric Cancer

ASCO 2016: Adding Daratumumab to Bortezomib and Dexamethasone Markedly Improves Outcomes in Recurrent/Refractory Multiple Myeloma

ASCO 2016: Atezolizumab Benefits Patients With Advanced Bladder Cancer

ASCO 2016: Tandem Autologous Stem-Cell Transplant Improves Outcomes for Children With High-Risk Neuroblastoma

ASCO 2016: New Antibody-Drug Conjugate Shows Early Promise in Small Cell Lung Cancer

ASCO 2016: Temozolomide Chemotherapy Plus Short-Course Radiotherapy Improves Survival in Elderly Patients With Glioblastoma

ASCO 2016: 10 Years of Aromatase Inhibitor Therapy Reduces Breast Cancer Recurrence Without Compromising Quality of Life in Postmenopausal Patients

ASCO 2016: Rucaparib Shows Clinical Benefit in BRCA-Mutated Pancreatic Cancer

ASCO 2016: Maintenance Lenalidomide After Autologous Stem Cell Transplantation Improves Survival in Multiple Myeloma

ASCO 2016: Locoregional Surgery Followed by Standard Therapy Improves Survival vs Standard Therapy Alone in Stage IV Breast Cancer

ASCO 2016: Nivolumab Alone or in Combination With Ipilimumab Active in Recurrent Small Cell Lung Cancer

ASCO 2016: Innovative Direct-to-Patient Outreach May Accelerate Breast Cancer Research

ASCO 2016: Liquid Biopsy May Help Guide Treatment Decisions for Patients With Advanced Solid Tumors

ASCO 2016: Precision Medicine Approach May Expand Therapeutic Options for Patients

ASCO 2016: Chemotherapy Improves Outcomes for Certain Patients With Anaplastic Glioma

ASCO 2016: Adding Capecitabine Chemotherapy to Gemcitabine Extends Survival After Pancreatic Cancer Surgery

ASCO 2016: Biosimilar Shows Comparable Efficacy and Safety to Trastuzumab in HER2-Positive Metastatic Breast Cancer

ASCO 2016: Adding Intraperitoneal Chemotherapy to Intravenous Chemotherapy Slows Ovarian Cancer Progression

Statement from FDA Commissioner Robert Califf, MD, on the Release of the Final Individual Patient Expanded Access Form

5-Year Results of DASISION Trial of Dasatinib vs Imatinib in CML

Poorer Adherence to Endocrine Treatment Associated With Poorer Outcome in Postmenopausal Hormone Receptor–Positive Breast Cancer

FDA Approves EGFR Mutation–Detecting Blood Test for Non–Small Cell Lung Cancer

FDA Approves New Diagnostic Imaging Agent to Detect Rare Neuroendocrine Tumors

Retroviral Replicating Vector That Delivers Cytosine Deaminase to Cancer Cells Active in Recurrent Glioblastoma

Nearly 20% of Patients With Ovarian Cancer Do Not Undergo Surgery

ASCO Guideline on Endocrine Therapy for Hormone Receptor–Positive Metastatic Breast Cancer

Study Finds Adding Adjuvant Oxaliplatin to Fluoropyrimidine of Benefit in Deficient Mismatch Repair Colon Cancer

Vulnerable Hospitals, Cancer Surgery Readmissions, and Penalizing Payment Programs

Survival Benefit Reported With Radiotherapy vs Surgery Alone in Retroperitoneal Sarcoma

ASCO Value Framework Update: A Statement by Julie M. Vose, MD, MBA, FASCO

FDA Approves New Diagnostic Imaging Agent to Detect Recurrent Prostate Cancer

Breast Cancer Risk From Modifiable and Nonmodifiable Risk Factors Among White Women in the United States

International Prognostic Index for Patients With Chronic Lymphocytic Leukemia

Early Lapatinib-Related Rash Associated With Improved Outcome in Breast Cancer

Women With New-Onset Atrial Fibrillation May Be at Increased Risk for Malignant Cancer

Play-Based Procedural Preparation May Aid Children Undergoing Cranial Radiation Therapy

New ASCO Cervical Cancer Guidelines Address Global Resource Disparities

QOPI-Certified Practices Eligible to Receive Discount on Medical Malpractice Rates

External Validation of a Prediction Tool for Chemotherapy Toxicity in Older Patients With Cancer

DDW 2016: Low-Residue Diet Prior to Colonoscopy Shows Improved Tolerance and Bowel Preparation vs Clear Liquid Diet

Leisure-Time Physical Activity Reduces Risk of Multiple Cancer Types

DDW 2016: Racial Disparities Found in Liver Cancer Survival Rates

DDW 2016: Endoscopist’s Knowledge of Positive Cologuard Test Improves Colonoscopy Performance

DDW 2016: Rates of Colorectal Cancer Continue to Increase in Those Under 50

Racial Disparities in Early Supportive Medication Use and End-of-Life Care Among Medicare Patients With Stage IV Breast Cancer

Prolonged Survival Reported With First-Line FOLFIRINOX in Locally Advanced Pancreatic Cancer

Body Mass Index and Mortality in Patients With Colorectal Cancer

Survey Finds Most Americans Unlikely to Enroll in Clinical Trials

Study Finds Many Terminal Patients Unaware of Their Impending Death

Clinically Relevant Mutations Identified Through Sequencing of Cerebrospinal Fluid of Patients With CNS Cancers

Long-Term Survival Benefit With Adjuvant Tamoxifen in Premenopausal Women With Estrogen Receptor–Positive Breast Cancer

Liquid Biopsy–Based Test Appears Comparable to Standard Tissue Testing in Detecting BRAF V600 Mutations

HIV-Infected Patients With Cancer May Be Likely to Receive Cancer Treatment

Use of ROS1 Immunohistochemical Staining in Screening for ROS1 Translocations in Lung Cancer

Study Finds No Benefit of Adding Pictilisib to Fulvestrant in Aromatase Inhibitor–Resistant Breast Cancer

French Trial Shows Benefit of Adding Short-Term Hormone Therapy to Salvage Radiotherapy for Rising PSA After Prostatectomy

Characterization of Molecular Differences in Cancer Between Male and Female Patients

Specific Version of the FCGR2A Gene Identifies Colorectal Cancer Patients Likely to Benefit Most From Cetuximab

Physician Recommendation May Influence Racial Disparity in BRCA1/2 Testing in Women With Breast Cancer

Venetoclax Produces High Response Rate in Relapsed or Refractory CLL With 17p Deletion

Use of Complementary and Alternative Medicine Affects Breast Cancer Chemotherapy Initiation

T-Cell Bim Levels May Reflect Responses to Anti–PD-1 Cancer Therapy

ASCO 2016: Precision Medicine Yields Better Outcomes for Patients in Phase I Clinical Trials

ASCO 2016: Early Palliative Care Provides Benefits for Family Caregivers of Patients With Cancer

ASCO 2016: PD-1 Inhibitor Pembrolizumab Provides Long-Term Survival Benefit for Patients With Advanced Melanoma in KEYNOTE-001

ASCO 2016: Left- vs Right-Sided Primary Tumor Location Predicts Survival in Metastatic Colorectal Cancer

ASCO 2016: Autologous Stem Cell Transplant Remains Relevant in Multiple Myeloma, Even in Era of Novel Agents

FDA Approves Atezolizumab for Advanced Urothelial Carcinoma

FDA Grants Accelerated Approval to Nivolumab in Classical Hodgkin Lymphoma

AATS 2016: Strategies for Increasing Survival In Soft-Tissue Sarcoma Patients With Lung Metastases Undergoing Resection

AATS 2016: Stage IIIA NSCLC Survival Rates Improved When Care Included Four Specific Quality Measures

ATS 2016: Untreated Severe Obstructive Sleep Apnea Associated With Increased Aggressiveness of Cutaneous Melanoma

Outcomes With Palbociclib at Altered Dose and Schedule in Liposarcoma

Adding Bevacizumab to Letrozole Improves Progression-Free Survival but Increases Toxicity in Metastatic Breast Cancer

No Survival Benefit Reported With Chemoradiotherapy vs Continued Chemotherapy in Controlled Locally Advanced Pancreatic Cancer

Addition of Ixazomib to Lenalidomide/Dexamethasone Improves Progression-Free Survival in Relapsed/Refractory Multiple Myeloma

FDA Approves Lenvatinib in Combination With Everolimus in Advanced Renal Cell Carcinoma

Combining Two FDA-Approved Diagnostic Tests Increased Detection of High-Grade Cervicovaginal Lesions

American Cancer Society Report Assesses Progress Against Goals Set for Nation 25 Years Ago

Same vs Different Order for Second Readings of Mammograms in Rates of Breast Cancer Detection

Pembrolizumab Active in PD-L1–Positive Advanced Gastric and Metastatic Triple-Negative Breast Cancers

FDA Grants Selumetinib Orphan Drug Designation for Adjuvant Treatment of Differentiated Thyroid Cancer

AUA 2016: IsoPSA, a Novel, Structure-Based Biomarker Test for Prostate Cancer, Explored in a Multicenter Prospective Trial

Women With Breast Cancer Who Are Knowledgeable About Their Tumor Characteristics Are More Likely to Receive Guideline-Recommended Treatment

ASCO Urges CMS to Withdraw Medicare Part B Demo in Formal Comments

Factors Associated With Response to Dabrafenib/Trametinib in BRAF Inhibitor–Refractory Metastatic Melanoma

Adjuvant MAGE-A3 Immunotherapeutic Shows No Benefit in Resected MAGE-A3–Positive NSCLC

Study of SEER Data Identifies Racial/Ethnic Disparities in Survival in Patients With Young-Onset Colorectal Cancer

No Progression-Free Survival Benefit for First-Line Neratinib/Paclitaxel vs Trastuzumab/Paclitaxel in Metastatic HER2-Positive Breast Cancer

AUA 2016: Relationship Between Testosterone Therapy and Prostate Cancer Explored

AUA 2016: Cell-Cycle Progression Score Provides Significant Prognostic Information in Patients With Gleason Score < 7

AUA 2016: BRCA Gene Mutations Associated With Increased Prostate Cancer Risk

AUA 2016: Adjuvant Chemotherapy After Radical Prostatectomy May Benefit Men at High Risk for Relapse

Benefit of Dexamethasone and High-Dose Methotrexate in Children/Young Adults With High-Risk B-Acute Lymphoblastic Leukemia

Risk Factors for Acute Pancreatitis in Children/Young Adults With Acute Lymphoblastic Leukemia

Early Study Looks to Achieve Chloride Homeostasis Through Gene Transfer to Alleviate Cancer-Related Neuropathic Pain

Study Explores Differential Localization of Glioblastoma Subtypes and Pathogenesis

Study Finds Benefit of Surveillance for Pancreatic Cancer in High-Risk Individuals

Little Apparent Activity of Cetuximab in Refractory Metastatic Colorectal Cancer With KRAS G13D Mutation

Spectrin Gene Identified as a Biomarker in HPV-Negative Oral Cavity Squamous Cell Carcinoma

Potential Targets for Loss of Appetite/Cachexia Related to Interleukin 18 Activity Identified in Early Studies

Assessing the Accuracy and Readability of Online Health Information for Patients With Pancreatic Cancer

Trastuzumab/Lapatinib Active in Refractory, KRAS Codon 12/13 Wild-Type, HER2-Positive Metastatic Colorectal Cancer

Pembrolizumab Active in Virus-Positive and ‑Negative Advanced Merkel Cell Carcinoma

FDA Grants Priority Review for BLA for Olaratumab in Advanced Soft-Tissue Sarcoma

FDA Grants sBLA for Blinatumomab in Pediatric Patients With Ph–Negative Relapsed/Refractory B-Cell Precursor ALL

Similar Outcomes Reported With ABVD vs BEACOPP in High-Risk Advanced Hodgkin Lymphoma

Effects of High Residential Segregation and Neighborhood Characteristics on Early-Stage NSCLC Surgery

ESTRO 2016: New Study Sheds Light on Mastectomy vs Breast-Conserving Therapy in Older vs Younger Patients With Early Breast Cancer

ESTRO 2016: Radiotherapy vs Chemotherapy in a Study of Patients With Early Stage II Testicular Cancer

Study Finds Cancer Mortality Risks From Long-Term Exposure to Ambient Fine Particulate Matter

Tight Junction Protein 1 May Identify Sensitivity to Proteasome Inhibitors in Patients With Multiple Myeloma

ESTRO 2016: SBRT in Early-Stage Lung Cancer Linked to Increased Risk of Noncancer Deaths

ESTRO 2016: Radiation and L19-IL2 Immunotherapy Combination Shows Activity in Preclinical Models

ESTRO 2016: Failure to Publish Phase III Radiotherapy Trial Results Exposes Patients to Risks Without Providing Benefits for Others

Genomic Profiling of Orbital and Ocular Adnexal Lymphomas

Study Links Residential Radon Exposure to Increased Risk of Hematologic Malignancies in Women

Study Finds No Association Between Anthracycline-Based Chemotherapy and Cognitive Decline in Women With Breast Cancer

Cancer Screening Using Digital Mammography Alone or With Tomosynthesis in Varying Breast Densities

Validation of Rapid Plasma Genotyping for Detecting EGFR and KRAS Mutations in Advanced Lung Cancer

Poor Understandability of Dense Breast Notifications Sent to Women Following Screening Mammography

New Study Suggests Cholesterol Levels, Not Statins, Influence Colorectal Cancer Risk

Canadian Study Suggests Increased Risk of Cardiac Dysfunction With Trastuzumab-Based Regimens for Breast Cancer

A Critical Analysis of Early Bladder Cancer Recurrence After Laparoscopic Radical Cystectomy

ASCO Adapts CCO Guideline on Selection of Optimal Adjuvant Therapy for Breast Cancer

Donor Epstein-Barr Virus Status Affects Risk for Graft-vs-Host Disease but Not Survival in Acute Leukemia After HSCT

Addition of Everolimus to Trastuzumab and Chemotherapy May Benefit Some Patients With Advanced HER2-Positive Breast Cancer

Solid Organ Transplant Recipients With Preexisting Malignancies in Remission May Be More Likely to Die, Develop New Cancers

Stereotactic Body Radiation Therapy May Offer a Higher Cure Rate in Prostate Cancer Than More Traditional Approaches

FDA Grants Breakthrough Designation to Nivolumab in Squamous Cell Carcinoma of the Head and Neck

FDA Approves Cabozantinib in Patients With Renal Cell Carcinoma Who Have Received Prior Antiangiogenic Therapy

AACR 2016: Neoadjuvant Trastuzumab Emtansine Plus Pertuzumab May Improve Outcomes for Women With HER2-Positive Breast Cancer

Study Finds Radiosensitivity Differences Between Liver Metastases Based on Primary Histology

Amplification of 9p24.1 Associated With Advanced Stage and Poorer Outcome in Classic Hodgkin Lymphoma

Advantage of Afatinib vs Gefitinib in First-Line Treatment of EGFR-Mutant NSCLC

AACR 2016: Genomic Variants May Influence Risk for Breast Cancer After Chest Radiotherapy to Treat Childhood Cancer

AACR 2016: Cologuard Detected Colorectal Cancer in Previously Unscreened Patients

KIR3DL1 and HLA-B Allele Combinations May Impact Response to Treatment in Neuroblastoma

AACR 2016: Nivolumab Improved Survival for Patients With Head and Neck Squamous Cell Carcinoma

Adjuvant Trastuzumab May Be Insufficiently Used in Older Women With Breast Cancer

Adding Rituximab to Dose-Dense Chemotherapy May Be of Benefit in Burkitt Lymphoma

AACR 2016: Delays in Radiation Therapy Increase Chance of Breast Tumor Development in Women Treated for DCIS

AACR 2016: Comparison of Three Different PD-L1 NSCLC Diagnostic Tests Shows a High Degree of Concordance

AACR 2016: Certain Oral Bacteria May Be Associated With Increased Pancreatic Cancer Risk

Interim FDG-PET Response-Adapted Therapy May Be of Benefit in Hodgkin Lymphoma

ASCO Statement on Human Papillomavirus Vaccination for Cancer Prevention

Dabrafenib Active in BRAF-Mutant Metastatic NSCLC

AACR 2016: Palbociclib Shows Antiproliferative Activity in Early-Stage Breast Cancer

AACR 2016: 5-Year Survival Rates for Patients With Metastatic Melanoma Treated With Nivolumab Much Higher Than Historical Rates

AACR 2016: Report Identifies Considerations for Alternative Payment Models for Cancer Care

Family-Focused Therapy Continued Into Bereavement Benefits High-Risk Families

Pazopanib of Benefit in Imatinib- and Sunitinib-Resistant GIST in French Phase II Trial

Hormone Combination Therapy May Increase Risk of Breast Cancer in African American Women

CCR2 Inhibitor Active in Combination With FOLFIRINOX in Advanced Pancreatic Cancer

French Study Suggests No Apparent Benefit of Bevacizumab in Nonmetastatic HER2-Negative Inflammatory Breast Cancer

AACR 2016: MammaPrint Genetic Test Can Reduce Use of Adjuvant Chemotherapy Among Early-Stage Breast Cancer Patients

AACR 2016: LOXO-101 Shows Continued Promise in Patients Whose Tumors Had NTRK Gene Fusions

AACR 2016: RAF-Targeted Therapeutic BGB-283 Shows Early Promise Against Tumors With BRAF and RAS Mutations

ELCC 2016: Studies Confirm Benefit of Plasma Genotyping to Predict Treatment Benefit in Patients With Non–Small Cell Lung Cancer

ELCC 2016: Patients With EGFR-Expressing Non–Small Cell Lung Cancer Benefit Most From Necitumumab Added to Chemotherapy

ASBS 2016: Fertility Counseling in Women of Childbearing Age After Breast Cancer

Hypofractionated Radiotherapy Not Inferior to Conventional Radiotherapy in Low-Risk Prostate Cancer

Higher EZH2 and Ki67 Expression May Be Associated With Aggressive Basal Cell Carcinoma

Some Diagnostic Variability in Interpreting Breast Biopsy Slides

ELCC 2016: Osimertinib Given as First-Line Treatment May Alter Biology of EGFR-Mutated Non–Small Cell Lung Cancer

ELCC 2016: Immunotherapy With Live Bacterium Improves Response Rate in Malignant Pleural Mesothelioma

Differences in Marital Status and Cancer Mortality by Race/Ethnicity and Nativity Explored

Nomograms for Predicting Survival and Distant Metastasis After Resection of Localized Soft-Tissue Sarcoma of the Extremities

Cancer and Fertility Program Improves Patient Satisfaction With Information on Fertility Risks and Preservation

Greatest Benefit of Adjuvant Exemestane Seen in Premenopausal Women at Higher Risk of Breast Cancer Recurrence

FDA Accepts Supplemental Biologics License Application for Nivolumab in Classical Hodgkin Lymphoma, Grants Priority Review

The Parker Foundation Launches the Parker Institute for Cancer Immunotherapy With a $250 Million Grant

ILC 2016: High Rate of Cancer Recurrence Found in Patients With Hepatitis C Taking Direct-Acting Antiviral Treatments

Use of 21-Gene Recurrence Score Assay in Early-Stage Breast Cancer

Improved Overall Survival With Addition of Chemotherapy to Radiation in Low-Grade Glioma

Shorter Delays Between Diagnosis, Surgery, and Chemotherapy Initiation May Improve Survival in Breast Cancer

Significantly Increased Risk of Noncancer Hospitalizations Following Diagnosis of Prostate Cancer in the Elderly

FDA Accepts Supplemental Biologics License Application for Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer, Grants Priority Review

More Guidelines, Uniformity in Radiation Therapy Needed Following Chemotherapy, Surgery in Breast Cancer

Preclinical Studies Show Many Androgen-Deprivation Therapies May Suppress Adaptive Immune Responses

Prognostic Scoring System for Patients Undergoing Allogeneic Hematopoietic Cell Transplantation for Myelodysplastic Syndrome

Noninferiority of Gefitinib vs Erlotinib Not Established in Japanese Trial in Advanced Lung Adenocarcinoma

Acupuncture Improves Hot Flashes in Women With Breast Cancer in Italian Trial

Relatives of Patients With Carcinoma of Unknown Primary at Increased Risk for This and Other Cancers

ASCO Urges Aggressive Efforts to Increase HPV Vaccination and Prevent Cancer

FDA Approves Venetoclax for Chronic Lymphocytic Leukemia With 17p Deletion

Adding Ovarian Function Suppression to Tamoxifen Worsened Some Patient-Reported Outcomes in Premenopausal Women With Early Breast Cancer

Increased Rate of Nonoperative Management of Rectal Adenocarcinoma

In Early Brain Radiation Recovery Studies, Cranial Grafting of Stem Cell–Derived Therapy Improves Cognition and Reduces Neuropathology

p53- and Mevalonate Pathway–Driven Cancers Require Cell-Signaling Protein Arf6 for Metastasis and Drug Resistance

Next-Generation Sequencing Assay May Permit Accurate Detection of Mismatch Repair Deficiency in Colorectal Cancer

Dutch Study Indicates Low Locoregional Recurrence in Young Women With Early-Stage Breast Cancer

Evidence of Intracranial Benefit With Crizotinib in Advanced ALK-Positive NSCLC

UK Trial Shows Similar Survival With PET-CT Surveillance vs Planned Neck Dissection in Advanced Head and Neck Cancer

International Myeloma Working Group Recommendations for Myeloma-Related Renal Impairment

Improved Detection of Breast Cancer With Ultrasound vs Tomosynthesis in Mammography-Negative Dense Breasts

sFRP2 in Aged Melanoma Tumor Cells Drives Metastasis and Therapy Resistance

New Study Links Coffee Consumption to Decreased Risk of Colorectal Cancer

Racial/Ethnic Patterns of Morbidity and Mortality Among Childhood Cancer Survivors

Study Finds Decreased Use of Primary Breast-Conserving Surgery for Women in New York State

Adding 6 Months of Androgen Suppression to Radiotherapy Improves Disease-Free Survival in Intermediate- and High-Risk Prostate Cancer

MicroRNA miR-181a Reduces NFκB Signaling in Diffuse Large B-Cell Lymphomas

NCI Announces Blue Ribbon Panel to Help Guide Vice President Biden’s National Cancer Moonshot Initiative

Vitamin D Level Associated With Melanoma Outcome Independent of C-Reactive Protein Level

Pathologic Complete Response to Neoadjuvant Therapy Associated With Improved Outcomes in HER2-Positive Breast Cancer

Study Reports No Overall Benefit of Adding Farletuzumab to Chemotherapy in Relapsed Ovarian Cancer, but Potential Subgroup Benefit Identified

Glioblastoma Multiforme With Mismatch Repair Deficiency May Be Target for Immune Checkpoint Inhibition

Ultrasound Screening for Breast Cancer May Be Linked to Increased Detection of Invasive Tumors but More False-Positive Results

Effects of Chemotherapy on Pregnancy for Survivors of Childhood Cancer Treated Between 1970 and 1999

ENDO 2016: Engineered Ovary Implant Restores Fertility in Mice

ENDO 2016: BPA Changes Fetal Development of the Mammary Gland, Can Raise Breast Cancer Risk

TP53 Gene Variant S47 May Contribute to Increased Cancer Risk in People of African Descent

Widely Cited Prostate-Specific Antigen Screening Publications Influence Biopsy Rates and Associated Complications

Good Outcome Reported With Endocrine Therapy and Omission of Chemotherapy Based on 21-Gene Recurrence Score in Breast Cancer

Phase II Trial Shows Benefit of Adding Ramucirumab to Docetaxel in Previously Treated Advanced Urothelial Carcinoma

ASCO Endorses Cancer Care Ontario Recommendations on Decision-Making in Adjuvant Systemic Therapy for Early-Stage, Operable Breast Cancer

Lower Vitamin D Levels Associated With Adverse Pathology at Prostatectomy in Men With Localized Prostate Cancer

Increased Frequency of BRCA Mutation Testing in Young Women With Breast Cancer

Study Finds Adaptive Image-Guided Radiation Therapy for Bladder Preservation Clinically Feasible in Urinary Bladder Cancer

Endoscopic Mucosal Resection Is an Alternative to Surgery in Most Patients With Complex Colon Polyps

Lung Cancer Incidence and Mortality in Individuals With a Negative Low-Dose CT Prevalence Screen

FDA Approves Defibrotide Sodium for the Treatment of Hepatic Veno-Occlusive Disease Following Hematopoietic Stem Cell Transplantation

Danish Study Shows Increased Risk for Cancers in Addition to Breast Cancer in CHEK2 Mutation Heterozygotes

Greater Prognostic Value of Ki67 Index vs Cytology and Growth Pattern in Mantle Cell Lymphoma

Epoetin Alfa vs Best Standard of Care in Treatment of Anemia in Patients With Metastatic Breast Cancer Receiving Chemotherapy

ASCO Endorses European Association of Urology Guideline on Muscle-Invasive and Metastatic Bladder Cancer

PET Probe [18F]CFA Detects Deoxycytidine Kinase Activity, May Lead to New Ways to Improve Response to Treatment

Therapeutic Combinations May Prevent Resistance to CDK4/6 Inhibition in Estrogen Receptor–Positive Breast Cancer

DigniCap Scalp Cooling System Now Available for Women With Breast Cancer at 10 U.S. Cancer Treatment Centers

Meta-analysis of Gene-Expression Datasets Identifies Novel Five-Gene Pancreatic Cancer Classifier

No Treatment Failure or Survival Benefit but Less Toxicity With Comprehensive Geriatric Assessment in Elderly Patients With Advanced NSCLC

Digital Breast Tomosynthesis Shows Sustained Effectiveness in Breast Cancer Screening

Survivors of Adolescent and Young Adult Cancer May Be at Increased Risk of Cardiovascular Disease

Possible Overuse of PET to Detect Recurrence of Lung and Esophageal Cancers

Italian Study Suggests Benefit of Interim PET Response–Adapted Therapy in High-Risk Advanced Hodgkin Lymphoma

ASCO Guideline on Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy in Women With Early-Stage Invasive Breast Cancer

Japanese Trial Shows Reduced Risk of Subsequent Colorectal Adenomas and Polyps With Low-Dose Metformin

MRI-Guided Adaptive Reoptimization in Radiotherapy Shows Promise in Urinary Bladder Cancer Treatment

Low-Magnitude, High-Frequency Mechanical Stimulation May Improve Bone Mineral Density in Young Childhood Cancer Survivors

Microneedle Patch Delivers Localized Anti–PD-1 Antibody Immunotherapy to Melanoma in Preclinical Models

Increased Risk of Cardiovascular Disease Among Survivors of Some Adult-Onset Cancers

Neoadjuvant Nab-Paclitaxel Improves Pathologic Complete Response Rate vs Solvent-Based Paclitaxel in Early-Stage Breast Cancer

Long Noncoding RNA SAMMSON Linked to Malignant Melanoma

Survival Differs With Metastatic Site in Castration-Resistant Prostate Cancer

New American Cancer Society Guideline Addresses Long-Term Needs of Head and Neck Cancer Survivors

Study Finds Apitolisib Less Effective Than Everolimus in Metastatic Renal Cell Carcinoma

Clifford A. Hudis, MD, FACP, Named ASCO’s Next CEO

Unique Fellowship Aims to Lessen Global Cancer Burden by Training Foreign Medical Graduates in Surgical Oncology

Study Explores Genomic and Transcriptomic Features of Anti–PD-1 Resistance in Advanced Melanoma

Combination Hormone Use Linked to Increased Risk of Estrogen Receptor–Positive Breast Cancer in Postmenopausal African American Women

Enzalutamide Improves Progression-Free Survival vs Bicalutamide in Nonmetastatic and Metastatic Castration-Resistant Prostate Cancer

Swedish Study Shows Association of Survival Gain With Increased Surgeon Experience in Patients Undergoing Esophagectomy for Cancer

Assessment of Survival Impact of Atypical Responses With Pembrolizumab Treatment in Advanced Melanoma

Increased Travel Burden Decreases Likelihood of Receiving Radiation Therapy for Rectal Cancer Treatment

Modified CAR T Cells Overcome Immune Suppression, Effective Against Solid Tumors in Preclinical Models

Neratinib Improves Invasive Disease–Free Survival After Trastuzumab-Based Therapy in HER2-Positive Breast Cancer

Poorer Outcome With BRAF and KRAS Mutations in Microsatellite-Stable but Not Microsatellite-Unstable Colon Cancer

Occult Metastasis on Immunohistochemistry May Affect Survival in Stage I NSCLC

Hypofractionated Radiotherapy Not Noninferior to Standard Radiotherapy in Late Genitourinary and Gastrointestinal Toxicity in Prostate Cancer

Neurofeedback Reduces Pain, Increases Quality of Life for Cancer Patients Suffering From Chemotherapy-Induced Neuropathy

SGO 2016: Advanced Ovarian Cancer Caused by Genetic Mutations Linked to Better PFS and OS Following Treatment Including Bevacizumab

68Ga-DOTATATE PET/CT Improves Detection of Gastroenteropancreatic Neuroendocrine Tumors

Little Effect of Pretreatment Renal Function on Outcomes in Older Women Receiving Chemotherapy for Early-Stage Breast Cancer

Adding Cediranib to Platinum Therapy Increases Progression-Free Survival in Relapsed Platinum-Sensitive Ovarian Cancer

Update of ASCEND-1 Trial Shows Ceritinib Highly Active in ALK-Rearranged NSCLC, Including Intracranial Disease

Long-Term Follow-up of Prospective U.S. Cohorts Shows Reduced Risk of GI Tract Cancers With Regular Aspirin Use

Families of Cancer Decedents See Early Hospice, ICU Avoidance, and Death Outside the Hospital as Better End-of-Life Care

No Disease-Free Survival Benefit of Adjuvant Sunitinib or Sorafenib in High-Risk Nonmetastatic Renal Cell Carcinoma

Specific Form of CYP3A7 Gene Associated With Poor Outcomes for Patients With Several Cancer Types

Processed Meat Consumption May Increase Risk of Breast Cancer for Latinas

Dietary Glycemic Index Linked to Lung Cancer Risk in Non-Hispanic White Populations

Laboratory Study Explores How High-Fat Diet Influences the Development of Intestinal Tumors

Site of Death, Health-Care Utilization, and Hospital Expenditures for Patients Dying With Cancer in Developed Countries

Finnish Study Identifies Increased Cancer Risks in Patients With Neurofibromatosis Type 1

No Significant Survival Advantage for Rigosertib in High-Risk Myelodysplastic Syndromes, but Subgroups May Benefit

Atezolizumab Improves Survival vs Docetaxel in Advanced NSCLC in Relation to Increased PD-L1 Expression

Study Finds Many Patients With Breast Cancer Develop Symptoms of Post-Traumatic Stress Disorder; Symptoms Diminished Over 1 Year

Study Evaluates Patient/Oncologist Perceptions of Whole-Exome Sequencing in Advanced Cancer

Fosaprepitant Combination Reduces Risk of Emesis During Chemoradiotherapy for Cervical Cancer

Retrospective Analysis Suggests Benefit of Adding Cetuximab to Radiotherapy Irrespective of p16 Status in Oropharyngeal Carcinoma

Resensitization to Crizotinib via Acquisition of Lorlatinib ALK Resistance Mutation Reported in Patient With NSCLC

Alisertib Shows Activity With Irinotecan/Temozolomide in Relapsed or Refractory Neuroblastoma

Severe Adverse Event Clusters Identified Using NCI Common Terminology Criteria in Advanced Prostate Cancer

ASCO Report Finds U.S. Cancer Care System Ill-Equipped to Deliver New Advances to Patients

Early MRI Screening Reduces Risk of Breast Cancer Death for Survivors of Childhood Hodgkin Lymphoma

Adding Palbociclib to Fulvestrant Prolongs Progression-Free Survival in Hormone Receptor–Positive, HER2-Negative Metastatic Breast Cancer

Family Perspectives Support Advance Care Planning With Patient Preferences in End-of-Life Care

Single Dose of Trastuzumab Kickstarts Immune Response in Certain Breast Cancers

Atezolizumab Active in Previously Treated Locally Advanced or Metastatic Urothelial Carcinoma

Frequent Copy Number Gain of Genes for PD-1 Ligands in Squamous Cell Carcinoma of the Cervix or Vulva

FDA Approves Crizotinib for ROS1-Positive Metastatic NSCLC

Combination Therapy May Be Better Than Radiotherapy Alone to Treat Aggressive Brain Cancer, According to Early Study

Researchers Find Possible Association Between Oral Bacteria and Esophageal Cancer

High Expression of Epiregulin or Amphiregulin Predicts Benefit of Panitumumab in RAS Wild-Type Advanced Colorectal Cancer

Geriatric Assessment Is Key to Treatment Decisions for Patients 80 Years and Older With Breast Cancer

Comprehensive Genomic Analysis Reveals New Genetic Insights Into Malignant Mesothelioma

Hyperthermic Laser Surgery Disrupts Blood-Brain-Barrier in Glioblastoma, Opening Path for Chemotherapy

Loss of Skeletal Muscle Before or After Radiotherapy Linked to Poorer Survival in Head and Neck Squamous Cell Carcinoma

Adjuvant Endocrine Therapy for Primary Breast Cancer Treatment Associated With Increased Symptom Burden Over 12 Months

PET Scan Use in Follow-up Care for Lung and Esophageal Cancer Shows Wide Variation Between Hospitals, No Impact on Survival

Two Forms of Radiosurgery for Brain Metastases Are Equally Effective

Study Finds Most Patients With Melanoma Had Few Total Nevi and No Atypical Nevi

Genomic Alterations in Primary Invasive Lobular Breast Cancer

Half of Elderly Patients With Colorectal Cancer Receive Expensive Therapy With Little Survival Benefit

Children With Leukemia From High-Poverty Areas More Likely to Suffer Early Relapse

Anamorelin Increases Lean Body Mass in NSCLC Patients With Cachexia

Selective Internal Radiotherapy Does Not Improve Any-Site but Prolongs Liver-Specific Progression-Free Survival in Metastatic Colorectal Cancer

Neratinib Shows Some Activity in Previously Treated HER2-Positive Breast Cancer Brain Metastases

New Staging System for Human Papillomavirus–Related Oropharyngeal Cancer

Adding Immunotherapy to Radiofrequency Ablation in Colorectal Cancer With Liver Metastasis Shows Promise in Preclinical Models

Study Links Normal Stem Cells to Aggressive Prostate Cancer

New Biomarker Identifies Uveal Melanoma Patients at High Risk for Metastasis

Metabolic Phenotyping of Blood Plasma Allows for the Detection of Lung Cancer

Racial/Ethnic Variations in Lung Cancer Incidence and Mortality in the Women’s Health Initiative Study Cohort

Study Finds No Progression-Free Survival Benefit for Weekly Dose-Dense vs Every-3-Week Paclitaxel Plus Carboplatin in Ovarian Cancer

SSO 2016: Federal 'Moonshot' Fight Against Cancer Means More Resources for Surgical Oncology Professionals

Light Reflectance Technique May Improve Ability to Remove Prostate Cancer During Surgery

Breast Reconstruction Using Abdominal Tissue: Differences in Outcome With Four Techniques

Asian Trial Finds No Survival Benefit of Adding Gastrectomy to Chemotherapy in Incurable Advanced Gastric Cancer

Factors Associated With Early Mortality in Patients Receiving Adjuvant Therapy for Colon Cancer

Study Finds 36% Increase in Number of Male Smokers in India Over 17 Years

Malignant Brain Tumors Most Common Cause of Cancer Deaths in Adolescents and Young Adults

Improved Outcomes Reported With Adjuvant Therapy in Patients With Early-Stage SCLC Undergoing Complete Resection

Single-Center Study Evaluates Proton Radiotherapy for Pediatric Medulloblastoma

2016 Quality Care Symposium: New Triage System Decreases Emergency Room Visits by Oncology Patients in Florida

2016 Quality Care Symposium: Online Tool Improves Access to Information on Cancer Treatment Costs

2016 Quality Care Symposium: Study Suggests Many Women With Early Breast Cancer Receive Unnecessary Imaging Tests

Study Finds No Adverse Impact of Minimally Invasive Hysterectomy on Long-Term Survival in Endometrial Cancer

Phase III Trial Shows No Benefit of Afatinib vs Trastuzumab Plus Vinorelbine in HER2-Positive Metastatic Breast Cancer

FDA Approves Everolimus for Neuroendocrine Tumors of Gastrointestinal or Lung Origin

FDA Approves Obinutuzumab in Follicular Lymphoma

Cancer Statistics for African Americans, 2016

Weight and Height During Adolescence May Impact Future Risk of Developing Non-Hodgkin Lymphoma

Single-Center Trial Indicates No Benefit of Hepatic Artery Chemoembolization vs Embolization in Hepatocellular Carcinoma

Improved Melanoma-Specific Survival Reported With Wider Excision Margin in High-Risk Primary Melanoma

ASCO Commends Confirmation of Robert M. Califf, MD, as FDA Commissioner

Eye Movement Affected in Some Former Childhood Cancer Patients

First-in-Class Drug ONC201 Shows Potential for Some Blood Cancers

UK Trial Shows No Survival Benefit of Low–Molecular-Weight Heparin in Patients With Lung Cancer

ASCO Endorses Cancer Care Ontario Guideline on Active Surveillance for Management of Localized Prostate Cancer

Minimal Residual Disease Identified by NPM1 Mutation May Be Prognostic Marker for Poorer Outcome in Standard-Risk AML

ASCO Clinical Practice Guideline Update on Ovarian Suppression/Adjuvant Endocrine Therapy in Hormone Receptor–Positive Breast Cancer

Chemotherapy Preferable to Radiotherapy to Reduce Distant Pancreatic Cancer Recurrences

2016 Head and Neck Cancer Symposium: Induction Chemotherapy Does Not Predict Survival Advantage Over Concurrent Chemoradiation

FDA Approves Palbociclib in Combination With Fulvestrant in Hormone Receptor–Positive, HER2-Negative Advanced or Metastatic Breast Cancer

No Survival Benefit of Pemetrexed/Cisplatin Chemoradiation vs Standard Treatment in Nonresectable Stage III NSCLC

2016 Head and Neck Cancer Symposium: Chemoradiation May Increase Survival for a Subset of Elderly Head and Neck Cancer Patients

2016 Head and Neck Cancer Symposium: Most Recurrences of HPV-Positive Oropharyngeal Cancer Can Be Found Within 6 Months

Cultural Awareness and Sensitivity Among Oncology Surgeons Do Not Necessarily Result in Culturally Competent Care

Serum Tumor Marker Testing Overused, Especially for Solid Tumors

Antithymocyte Globulin Reduces Need for Immunosuppressants After Hematopoietic Cell Transplantation From Unrelated Donors

2016 Head and Neck Cancer Symposium: Uninsured and Medicaid Patients More Likely to Present With Advanced Tumors, Experience Cancer-Specific Mortality

2016 Head and Neck Cancer Symposium: Cost-Coping Strategies and Perceived Social Isolation in Locally Advanced Head and Neck Cancer

2016 Head and Neck Cancer Symposium: Study Maps Distinct Molecular Signatures of HPV-Positive Throat Cancer by Smoking Status

Inherited Genetic Variations That Lead to Severe Drug Toxicity in Pediatric Leukemia Discovered

Fecal Immunochemical Test Sensitive and Effective for Annual Colorectal Cancer Screening

Autoantibodies May Help Detect Lung Cancer Earlier

Updated Guidelines Recommend That Patients With Colorectal Cancer Undergo Colonoscopy After Cancer Resection

Norwegian Male Cancer Survivors Less Likely to Reproduce

Melanoma-Specific Survival Significantly Higher With Wider Excision Margins

Increased Risk of Severe Neurocognitive Impairment in Adult Survivors of Pediatric CNS Tumors

Study Finds Mechanism by Which Obesity Promotes Pancreatic and Breast Cancers

Gene Previously Observed Only in Brain Is Important Driver of Metastatic Breast Cancer

Intense Tumor Lymphocytic Infiltration Prognostic of Better Outcome in Resectable NSCLC

Eribulin Improves Overall Survival vs Dacarbazine in Advanced Liposarcoma or Leiomyosarcoma

Dutch Study Shows Increased Risk of Second Cancer for Survivors of Hodgkin Lymphoma During Long-Term Follow-up

Younger T Cells May Improve Immunotherapy for Pediatric Cancer

Study Examines Evolution of Cancer

High Conditional Survival for Patients With Metastatic Testicular Germ Cell Tumors Receiving First-Line Curative Therapy

Interruption of Radiation Therapy Due to Noncompliance Risks Cancer Recurrence

Study Finds Enzalutamide Increases Progression-Free Survival vs Bicalutamide in Metastatic Prostate Cancer

ACS/ASCO Breast Cancer Survivorship Care Guideline

Preclinical Device Hits Pancreatic Tumors With Drug Cocktail, Sparing the Body

Nanoparticle Therapy That Uses LDL and Fish Oil Kills Liver Cancer Cells

Study Finds Time Lag Between Positive Fecal Blood Test and Follow-up Colonoscopy

Reduction in Late Mortality in Childhood Cancer Survivors in the Childhood Cancer Survivor Study Cohort

Addition of TG4010 Vaccine to First-Line Chemotherapy Appears to Improve Progression-Free Survival in Advanced NSCLC

Possible Marker for Recurring HPV-Linked Oropharyngeal Cancers

Removal of Complex Renal Tumors Performed Safely by Robotic Surgery in Selected Patients

Transcription Factor CDX2 May Be Prognostic Biomarker in Stage II and III Colon Cancer

Increased Survival and Toxicity With Docetaxel, No Apparent Benefit of Zoledronic Acid in Prostate Cancer

New Assay Detects Persistent Disease in Leukemia Patients Thought to Be in Remission

Bone Loss Associated With Leukemia Therapy Occurs Sooner Than Previously Thought

Superior Long-Term Outcomes Linked to Axillary Pathologic Complete Response After Chemotherapy for Breast Cancer

UK Trial Shows Little Benefit of Pregabalin Combined With Palliative Radiotherapy for Cancer-Induced Bone Pain

World Cancer Day 2016: We Can. I Can.

ASCO Names Cancer Advance of the Year: Immunotherapy

American College of Physicians Issues Advice, Raises Questions About Best Practices for Hematuria as a Sign of Cancer

High Rate of Local Control Reported With High-Dose Hypofractionated Proton Beam Therapy in Liver Cancers

Higher Mortality Risk in Poor or Minority Adolescents and Young Adults vs White Patients With Hodgkin Lymphoma

Study Finds Association Between Androgen-Deprivation Therapy in Prostate Cancer and Risk of Alzheimer’s Disease

Higher Risk of Cancer Mortality in Solid-Organ Transplant Recipients

Sparing Ovaries and Removing Fallopian Tubes May Cut Cancer Risk, but Few Have Procedure

Abnormal Fused Gene Is a Triple Threat in Driving Pediatric Brain Tumors

Many Americans Favor a Tax Increase to Support the 'Moonshot' Cancer Initiative

Material and Psychological Financial Hardship for U.S. Cancer Patients

Higher Dietary Fiber Intake in Adolescence and Young Adulthood May Reduce Breast Cancer Risk

French Trial Shows Addition of First-Line Bevacizumab to Cisplatin/Pemetrexed Improves Survival in Malignant Pleural Mesothelioma

Afatinib Shows Clinical Benefit for Non–Small Cell Lung Cancer Patients With Brain Metastases

Study Finds Need for Improved End-of-Life Care for Parents With Terminal Cancer

Increased Breast Cancer Risk Reported in Childhood Sarcoma and Leukemia Survivors With No History of Chest Radiotherapy

UK Study Finds No Association Between Self-Reported Unhappiness and Mortality Risk

Study Finds Alectinib Highly Active in ALK-Positive, Crizotinib-Resistant NSCLC

Swedish Study Indicates No Pregnancy-Related Increase in Risk of Relapse in Hodgkin Lymphoma

Study Shows Inferior Outcomes for African American Pediatric Lymphoma Patients

Risk Factors for Lymphedema in Patients Treated for Breast Cancer

DNA Damage and Repair Pathway Signature May Be Associated With Prognosis After Prostatectomy in High-Risk Prostate Cancer

FDA Approves Eribulin Mesylate in Unresectable or Metastatic Liposarcoma

100% of NCI-Designated Cancer Centers Endorse the Promotion of the HPV Vaccination for Cancer Prevention

One in Seven Colorectal Cancer Patients Diagnosed Before Recommended Screening Age

STS 2016: Race, Lower Socioeconomic Status Linked With Worse Survival Following Esophageal Cancer Surgery

STS 2016: Body Mass Index Linked With Complications After Lung Cancer Surgery

UK Study Suggests Association Between Screen-Detected Ductal Carcinoma in Situ and Reduced Invasive Interval Breast Cancers

Long-Term Trial Finds Similar Survival Rates With Several Chemotherapy Regimens for Advanced Hodgkin Lymphoma

Nivolumab Plus Ipilimumab Receives Expanded FDA Approval in Unresectable or Metastatic Melanoma Across BRAF Status

FDA Approves Carfilzomib as Single Agent or in Combination in Relapsed/Refractory Multiple Myeloma

Study Finds Fecal Immunochemical Test Effective for Annual Colon Cancer Screening

American College of Physicians Issues Advice for Evaluating Hematuria as a Marker of Urinary Tract Cancer

2016 GI Symposium: Tumor-Treating Fields Plus Chemotherapy May Be Safe as First-Line Treatment in Advanced Pancreatic Cancer

2016 GI Symposium: Irinotecan Liposome Injection in Metastatic Pancreatic Cancer: Updated Results of the Phase III NAPOLI-1 Study

2016 GI Symposium: New Regimen for Locally Advanced Rectal Cancer as Effective as, but Less Toxic Than, Chemoradiation

Inherited Genetic Markers May Predict Melanoma Survival and Help Plot Course of Disease

2016 GI Symposium: Everolimus Slows Growth of Neuroendocrine Tumors

2016 GI Symposium: New Targeted Hormone-Radiation Treatment Slows Growth of Midgut Neuroendocrine Tumors

New NCCN Guidelines for Vulvar Cancer Available

Study Finds Adjuvant Anastrozole Reduces Recurrence Risk vs Tamoxifen in Postmenopausal Women With Ductal Carcinoma in Situ

Report Finds Benefit With Third-Generation EGFR Inhibitor After Progression on Another Such Agent in Patients With Lung Cancer

Quality Improvement Projects Aim at Reducing Prescribing Errors for Chemotherapy

No Association Seen Between New or Worsening Aromatase Inhibitor–Related Musculoskeletal or Vasomotor Symptoms and Relapse-Free Survival

Pregnancy-Associated Melanoma Is Linked With Higher Death Rates

New Precision Medicine Guidelines Aimed at Improving Personalized Cancer Treatment Plans for Patients

New Target Identified for Reducing Metastasis

Increased Cancer Mortality Rate Among Recipients of Solid-Organ Transplants

Increased Response Rate With Higher Dose of Obinutuzumab Monotherapy for Patients With Chronic Lymphocytic Leukemia

FDA Approves Ofatumumab for Patients With Chronic Lymphocytic Leukemia in Complete or Partial Response

New Method to Improve Preoperative Diagnosis of Ovarian Cancer Based on Ultrasound

Higher Risk of Radiation-Induced Breast Cancer Found in Women Screened More Frequently and in Women With Larger Breasts

UK Study Suggests Potential Mortality Benefit of Ovarian Cancer Screening in Postmenopausal Women

Use of 21-Gene Recurrence Score May Be Linked to Chemotherapy Use and Health-Care Costs in Women With Breast Cancer

Palliative Care Initiated in the Emergency Department Associated With Improved Quality of Life

New Findings May Enhance PARP Inhibitor Therapy in Breast Cancer

High Risk on Breast Cancer Risk Prediction Tools Associated With More Favorable Disease Characteristics

Use of Antilymphocyte Globulin Appears to Reduce Chronic Graft-vs-Host Disease After Allogeneic Stem Cell Transplantation in Acute Leukemia

Survivorship Symposium 2016: ASCO Announces New Award Recognizing Extraordinary Contributions to Cancer Survivorship Care

Survivorship Symposium 2016: Persistent Chemotherapy-Induced Peripheral Neuropathy Is Common in Female Cancer Survivors

Survivorship Symposium 2016: Study Finds That Less Than Half of Survivors of Hodgkin Lymphoma Received All Recommended Follow-up Care

Survivorship Symposium 2016: Study Finds Personalized Survivorship Care Plans Improve Health Outcomes in Low-Income Breast Cancer Survivors

Link Between Obesity and Increased Risk of Colorectal Cancer Revealed in Preclinical Models

Japanese Study Shows Oral Fluoropyrimidine S-1 Is Noninferior to Taxanes as First-Line Treatment of HER2-Negative Metastatic Breast Cancer

Patients Diagnosed With Stage I to III Rectal Cancer at Younger Age May Have Increased Risk for Positive Lymph Nodes

Ultrasound Guidance Lowers Risks of Thoracic Nerve Block Technique for Mastectomy

Journal of Oncology Practice Goes to Monthly Distribution With New and Enhanced Resources

HPV Vaccine Uptake Is Highest Among Girls in High-Poverty and Majority Hispanic Communities

Nonsignificant Improvement in Disease-Free Survival With Adjuvant Lapatinib/Trastuzumab vs Trastuzumab in Early HER2-Positive Breast Cancer

Increased Risk of Carcinoma of Unknown Primary and Other Cancers in Relatives of Patients With This Type of Cancer

Blood Test That Monitors ctDNA Better Than the Standard in Tracking Metastatic Melanoma

ASCO Calls for Improvements to Clinical Pathway Programs in Oncology

Pembrolizumab Improves Survival vs Docetaxel in Previously Treated PD-L1–Positive Advanced NSCLC

Telephone and In-Person Counseling for Weight Loss Effective in Women Treated for Breast Cancer

Phase I Trial Shows Injectable Agent Illuminates Cancer During Surgery

AACR, Triple Negative Breast Cancer Foundation, and Carol’s Crusade for a Cure Foundation Partner to Offer Grant Opportunity

Study Shows ACA Coverage Expansion Resulted in Increased Cervical Cancer Diagnosis at Early Stage in Young Women

Use of 21-Gene Recurrence Score vs Adjuvant! Online May Alter Chemotherapy Decisions in Breast Cancer

GU Symposium 2016: Even After Antiandrogen Therapy, Docetaxel Remains Useful in Prostate Cancer

Two DPYD Variants Join List of Variants Predictive of Fluoropyrimidine Toxicity

Radiation Therapy Lowers Risk of Cancer Recurrence in Patients Undergoing Pancreatic Surgery

No Benefit Shown With Afatinib in HER2-Positive Breast Cancer With Progressive Brain Metastases

GU Symposium 2016: Updated Results of IMvigor 210 Show Durable Response Rates With Atezolizumab in Advanced Bladder Cancer

GU Symposium 2016: New Blood Test Technology Shows Promise for Guiding Prostate Cancer Treatment Decisions

GU Symposium 2016: Cabozantinib Improves Upon the Standard of Care for Advanced Kidney Cancer

GU Symposium 2016: Regular Aspirin Use May Reduce Risk of Dying From Prostate Cancer

Italian Study Shows Low-Dose Morphine Better Than Weak Opioids in Relieving Moderate Cancer Pain

Long-Term Follow-up of Risk of Cancer Among Twins

Palliative Care Offers Greater Cost Savings for Cancer Patients With Multiple Chronic Conditions

Everolimus Improves Progression-Free Survival in Advanced Neuroendocrine Tumors of the Lung or Gastrointestinal Tract

Study Finds Cardiovascular Disease Is Prevalent and Often Asymptomatic in Childhood Cancer Survivors

New Study Suggests Benefits of Regular Mammography Extend to the Elderly

National Cancer Database Study Indicates Racial Differences in Neoadjuvant Chemotherapy Use in Women With Breast Cancer

American Psychosocial Oncology Society Endorses Psychosocial Standards of Care for Children With Cancer and Their Families

Tumor Tissue Specimens and Associated Analyses Appear to Be a Significant Barrier to Clinical Trial Enrollment

DNA Repair Enzyme Identified as a Potential Brain Cancer Drug Target

Electronic Symptom Self-Reporting During Cancer Treatment May Be Associated With Better Quality of Life and Other Clinical Benefits

Adding Ibrutinib to Bendamustine/Rituximab May Increase Progression-Free Survival in Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Gene Thought to Suppress Cancer May Actually Promote Spread of Colorectal Cancer

Periodontal Disease Linked to Increased Risk of Breast Cancer in Postmenopausal Women, Especially Smokers

Travel Distance Is Still a Barrier to Breast Reconstruction After Mastectomy

Study Reports Improved Survival With Lapatinib and CapeOx in Asian and Younger Patients With HER2-Positive Advanced Gastroesophageal Adenocarcinoma

Even Before Affordable Care Act, Cancer Survivors in Nonexpansion States Had Less Health-Care Access

More Than One-Third of Patients With Metastatic Cancer Continue to Work

Stereotactic Body Radiotherapy vs Radiofrequency Ablation in Inoperable Nonmetastatic Hepatocellular Carcinoma

Patient-Reported Outcomes With Adjuvant Anastrozole vs Tamoxifen in Postmenopausal Women With Ductal Carcinoma in Situ

ESMO Asia 2015: Results From the KEYNOTE-010 Trial Show Pembrolizumab Benefit in Patients With NSCLC

ESMO Asia 2015: Cancer Drives Patients to Poverty in Southeast Asia

ESMO Asia 2015: Immunotherapy and Targeted Therapy Provide New Options for Difficult-to-Treat Head and Neck Cancer

ESMO Asia 2015: Afatinib a Better Choice for EGFR-Mutated Lung Cancer in First-Line Treatment

FDA Expands Pembrolizumab Label to Include Approval in Initial Treatment of Unresectable or Metastatic Melanoma

Follow-up Times for Colorectal Cancer Screening Abnormalities Lag Behind Others

Mental Health Status Prior to Radical Cystectomy Can Indicate Risk of Complications

Characterization of Pathogenic Mutations in Melanoma Progression

Potential Overdiagnosis of Contralateral Breast Cancer With Preoperative Magnetic Resonance Imaging in Older Women With Breast Cancer

Fractionated Stereotactic Radiation More Effective Than Single-Dose Radiation in Pituitary Tumors

Higher BMI Associated With Increased Risk of Breast Cancer–Related Lymphedema

Study Finds NSCLC to Be Genetically Different in Younger and Older Patients, Requiring Different Treatment Approaches

Swedish Screening Model Improves Performance of Prostate Cancer Screening vs PSA Alone in Men Aged 50–69 Years

Bruce E. Johnson, MD, FASCO, Elected ASCO President for 2017–2018 Term

Access to Minimally Invasive Hysterectomies in Early Uterine Cancer Remains Persistently Limited

New ‘Condensed’ Grading System Shown to Be Accurate for Predicting Prostate Cancer Outcomes

Adding Ibrutinib to Bendamustine/Rituximab Increases Progression-Free Survival in Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

Similar Outcomes Reported With Surgery vs Definitive Concurrent Chemoradiotherapy in Resectable Stage III NSCLC

Patients With Thyroid Cancer Report Poor Quality of Life Despite ‘Good’ Diagnosis

Preoperative Use of Blood-Thinning Drugs Is Safe for Patients With Cancer

Treatment Trends in Stage II and III Colorectal Cancer in the United States

Moore Scoring System Helps Identify Women With Advanced Cervical Cancer Who May Not Benefit From Bevacizumab

Germline ETV6 Variations as Basis of Novel Genetic Syndrome Associated With Childhood Acute Lymphoblastic Leukemia

Carpal Tunnel Syndrome in Patients Treated With Anastrozole in IBIS-II

HDAC Inhibitors May Help Prevent Cisplatin-Based Kidney Damage

FDA Allows Marketing of Cooling Cap to Reduce Hair Loss During Chemotherapy

Colorectal Cancer Risk Varies Based on Latino Subgroup Affiliation

Australian Single-Center Experience With Cutaneous Toxicity From Use of BRAF Inhibitor Alone or With MEK Inhibitor in Metastatic Melanoma

Homologous Recombination Deficiency Diagnostic Test Helps Identify Patients With Breast Cancer Likely to Respond to Platinum-Based Therapy

FDA Approves Alectinib for Advanced ALK-Positive NSCLC

FDA Approves Uridine Triacetate for Emergency Treatment of Fluorouracil or Capecitabine Overdose

SABCS 2015: Phase III BELLE-2 Trial Meets Primary Endpoint of Progression-Free Survival

SABCS 2015: Resistance of Estrogen Receptor–Positive Breast Cancer to Tamoxifen Therapy May Be Driven by APOBEC3B

SABCS 2015: Ado-Trastuzumab Emtansine Improved Overall Survival for Heavily Pretreated Patients With HER2-Positive Breast Cancer

SABCS 2015: No Significant Difference in Recurrence Rates Among Women With Ductal Carcinoma in Situ Taking Anastrozole or Tamoxifen

Alectinib Highly Active in Crizotinib-Refractory ALK-Rearranged NSCLC

Repeating Abnormal PSA Tests Reduces Number of Unnecessary Biopsies

Study Finds No Improvement in Diagnostic Accuracy of Digital Screening Mammography With Computer-Aided Detection

SABCS 2015: Patients With Ductal Carcinoma in Situ Receiving Anastrozole Reported Symptoms Different From Those in Patients Receiving Tamoxifen

SABCS 2015: Pathologic Complete Response to Presurgery Chemotherapy Improves Survival for Patients With Triple-Negative Breast Cancer

SABCS 2015: Breast-Conserving Therapy Provided Better Long-Term Outcome Than Mastectomy in Patients With Early-Stage Breast Cancer

SABCS 2015: ESR1 Gene Mutations Are Associated With Worse Overall Survival in Metastatic ER-Positive Breast Cancer

SABCS 2015: Mastectomy Plus Reconstruction Has Higher Complication Rates and Costs Than Lumpectomy Plus Radiation

SABCS 2015: Women With Luminal A Breast Cancer Did Not Benefit From Adjuvant Chemotherapy in Phase III Trial

SABCS 2015: Capecitabine Improved Outcomes for Breast Cancer Patients With Residual Disease After Presurgery Chemotherapy

SABCS 2015: Denosumab Improves Disease-Free Survival for Postmenopausal Patients With Hormone Receptor–Positive Breast Cancer

Patient Symptom Surveys Linked to Reduced ER Visits, Improved Survival and Quality of Life

Improved Overall Survival With Addition of Nanoliposomal Irinotecan to Fluorouracil/Leucovorin in Metastatic Pancreatic Cancer

Prognostic Factors in Men With Brain Metastases From Germ Cell Tumors

ASH 2015: Multiple Myeloma Patient Study Shows Promise for Natural Killer Cells

ASH 2015: Young Adults With Acute Lymphoblastic Leukemia Have Encouraging Survival With Pediatric Chemotherapy Regimen

ASH 2015: Updated Results of the Phase I/II GEN503 Study of Daratumumab in Multiple Myeloma

ASH 2015: High Response Rates, Long-Term Remissions in Relapsed/Refractory Pediatric ALL, Lymphomas After CTL019 Immunotherapy

European Trial Shows Front-Line Addition of Nintedanib to Standard Chemotherapy Improves Progression-Free Survival in Advanced Ovarian Cancer

Depressed Head and Neck Cancer Patients 3.5 Times Less Likely to Survive, Have Higher Recurrence Risk

Women’s Health Initiative Clinical Trial Suggests Endogenous Estrogens May Protect Against Colorectal Tumorigenesis in Postmenopausal Women

ASH 2015: Updated Results of Phase III Tourmaline-MM1 Study of Ixazomib in Multiple Myeloma

ASH 2015: Children With Acute Lymphoblastic Leukemia Benefit From Prophylactic Antibiotics During Induction Chemotherapy

ASH 2015: Ibrutinib Data Underscore Promise of Targeted Therapies as First-Line Approach for Patients With Chronic Lymphocytic Leukemia

ASH 2015: Combination Therapy With Idelalisib Improves Progression-Free Survival vs Bendamustine/Rituximab Alone in Relapsed/Refractory CLL

ASH 2015: Venetoclax Shows Promise for Ultra–High-Risk Chronic Lymphocytic Leukemia With 17p Deletion

Better Invasive Disease–Free Survival With Epirubicin/Cyclophosphamide and Docetaxel vs Epirubicin/Docetaxel and Capecitabine in Breast Cancer

Decreased Prostate-Specific Antigen Screening and Rate of Diagnosis in Early-Stage Prostate Cancer

Reduced Nonrelapse Mortality With Busulfan/Fludarabine vs Busulfan/Cyclophosphamide for Stem Cell Transplantation in Acute Myeloid Leukemia

ASH 2015: Adding Rituximab to Standard Chemotherapy in CD20-Positive Philadelphia Chromosome–Negative BCP-ALL Improves Event-Free Survival

ASH 2015: Midostaurin Improves Survival in Patients With FLT3-Mutated Acute Myeloid Leukemia Aged 18–60

ASH 2015: Test Creates Simulations That May Help Predict Drug Responses, Drive Personalized Treatment

ASH 2015: Researchers Identify Children Most at Risk of Overreporting Adherence to At-Home Chemotherapy Regimen

ASH 2015: Two Studies Focus on Treatment for Cancer-Associated Thrombosis

ASH 2015: Real-Time Classification System Identifies Leukemia Patients With High-Risk Clinical Features but Outstanding Outcomes

ASH 2015: Genetic Variants Discovered in Acute Lymphocytic Leukemia That Indicate Higher Risk for Osteonecrosis, Avascular Necrosis

ASH 2015: First-in-Human Trial Using Engineered Cells to Target Multiple Myeloma Shows Early Promise

ASH 2015: Engineered Donor T Cells May Eradicate Progressive Disease After Stem Cell Transplant

Systematic Review Informing ACS Updated Guideline for Breast Cancer Screening in Women at Average Risk

ASH 2015: American Society of Hematology Releases Compilation of Top Choosing Wisely Recommendations Relevant to Hematology

Researchers Use Ovarian Follicles to Preserve Fertility in Preclinical Models

Chemotherapy-Induced Peripheral Neuropathy May Be Associated With Cerebral Perfusion and Gray Matter Changes

Study Shows Abiraterone Acetate Is Useful Even in the Most Aggressive Prostate Cancers

Study Finds Increased Risk of Breast Cancer After False-Positive Screening Mammography

RSNA 2015: Subsolid Lung Nodules Pose Greater Cancer Risk to Women Than Men

Study Identifies Ovarian Cancer Cell Hierarchy

Benefit of Maintenance Bevacizumab-Erlotinib vs Bevacizumab After Bevacizumab-Based Induction Therapy in Metastatic Colorectal Cancer

Study Finds Better Outcome With Melphalan Plus ASCT vs Chemotherapy Plus Lenalidomide Consolidation in Multiple Myeloma

Intratumoral Heterogeneity of ALK Fusions and ALK/EGFR Co-alterations in Lung Adenocarcinomas

Majority of Men Who Forgo Aggressive Treatment for Prostate Cancer Are Not Monitored Appropriately

RSNA 2015: Study Suggests Breast Density Alone Not a Risk Factor for Cancer

Molecular Characterization of Papillary Renal Cell Carcinoma Shows Differences Between Type 1 and 2 Tumors

Prognostic Model for Survival in Advanced-Stage Mycosis Fungoides and Sézary Syndrome

RSNA 2015: Medicaid Expansion Improves Breast Cancer Screening for Low-Income Women

Female Hormone Supplements With Estrogen and Progestin Linked to Breast Cancer Risk in African American Women

FDA Approves Elotuzumab in Combination With Lenalidomide and Dexamethasone for Multiple Myeloma

German Phase II Trial Shows Benefit and Increased Toxicity With Addition of Sorafenib to Standard Therapy in Newly Diagnosed AML

Breast MRI After Mammography May Identify Additional Aggressive Cancers

Researchers Develop Mathematical Model to Forecast Metastatic Breast Cancer Survival Rates

Elevated C-Reactive Protein May Be Associated With Increased Breast Cancer Risk in Postmenopausal Women Not Using Hormone Therapy

FDA Approves Single-Agent Nivolumab for Previously Untreated BRAF Wild-Type Advanced Melanoma

FDA Approves Necitumumab Combination for Metastatic Squamous NSCLC

Molecular Prognostic Index Improves Risk Stratification of Early-Stage NSCLC

Meta-Analysis Indicates Noninferiority of Overall Survival With Intermittent vs Continuous Androgen-Deprivation Therapy in Prostate Cancer

Citywide Effort Boosts New York City's Colorectal Cancer Screening Rates

Vigorous Exercise and Healthy Habits May Dramatically Reduce Chance of Lethal Prostate Cancer for Men Over 60

FDA Approves Nivolumab to Treat Advanced Kidney Cancer

Risk of Undetected Cancer in Gynecologic Surgery Higher Than Previously Thought

Chitosane-Based Injectable Biogel Delivers Anticancer Agents Directly Into Tumors in Laboratory Setting

Predicted Burden of Breast Cancer in the United States

Phase II Study Shows No Benefit of Adding Vismodegib to Gemcitabine in Metastatic Pancreatic Cancer

Less Favorable Characteristics for Breast Cancer Diagnosed After Biennial vs Annual Screening in Premenopausal Women

FDA Approves Ixazomib in Combination With Lenalidomide and Dexamethasone for Multiple Myeloma

Self-Reported Fatigue Provides Independent Prognostic Information in Patients With Myelodysplastic Syndromes

Study Advances Potential Test to Distinguish Precancerous Pancreatic Cysts From Harmless Ones

Patients With Breast Cancer Who Have Prescription Drug Benefits, Higher Incomes More Likely to Start and Continue Hormonal Therapy

Users of Smokeless Tobacco Have Higher Levels of Nicotine and Toxicant Exposure Than Cigarette Smokers

Anemia Prevalent and Independently Associated With Functional Disability in Older Patients With Cancer

Two Studies Find Protein May Inhibit Prostate Cancer Bone Metastasis

Researchers Find Experimental Drug Reduces Ascites With Minimal Side Effects in Preclinical Studies

Study Finds Investigational Personalized Peptide Vaccination Increased Survival in Patients With Advanced Bladder Cancer

Prognostic Factors Identified in Patients With ALK‑Rearranged NSCLC and Brain Metastasis

Yoga Helps Maintain Quality of Life, May Lessen Side Effects in Men Undergoing Prostate Cancer Treatment

Kidney Failure and Its Treatment May Impact Cancer Risk

10-Year Results of MOSAIC Trial Show Continued Survival Benefit of Adjuvant FOLFOX4 in Stage III Colon Cancer

Increased Risk of Second Nonmelanoma Skin Cancer Among Patients Receiving Immunosuppressive Therapy

Healthy Diet May Reduce Risk of Ovarian Cancer in African American Women

Disparities in Colorectal Cancer Death Rates Take a Large Economic Toll

Rates of Curative Lung Cancer Surgery Vary by State

Single-Institution Experience Indicates Improved Outcomes With Higher Radiotherapy Doses in Inoperable Intrahepatic Cholangiocarcinoma

FDA Approves Daratumumab for Patients With Previously Treated Multiple Myeloma

Blood Test Detects Resistance to Aromatase Inhibitors in Breast Cancer Treatment

Researchers Call for Hospitals to Establish Bereavement Programs for Families of Deceased Patients

FDA Approves Osimertinib for EGFR T790M Mutation–Positive Non–Small Cell Lung Cancer After Progression on Prior EGFR-Blocking Therapy

Preclinical Study Reveals Why Chemotherapy May Be Compromised in Patients With Pancreatic Cancer

Some Rare HER2 Mutations May Not Be Capable of Causing Breast Cancer Growth

‘Substantial Number’ of Patients Requiring Palliative Radiotherapy for Stage IV NSCLC Are Overtreated

Shift Over Time in Treatment Patterns of Ductal Carcinoma in Situ

Previous Oral Contraceptive Use May Be Associated With Better Outcomes in Patients With Ovarian Cancer

Increased Meat Consumption May Be Linked to Elevated Kidney Cancer Risk

New Prediction Model May Provide More Accurate Assessment of Breast Cancer Risk in Hispanic Women

Investigational NAE Inhibitor Pevonedistat Shows Potential Activity in Patients With Relapsed/Refractory Lymphoma

FDA Approves Cobimetinib in Combination With Vemurafenib for Advanced Melanoma

Cancer Survivors Are Less Likely to Receive Callbacks From Potential Employers

ABC3: Experts Create New Consensus Guidelines for Advanced Breast Cancer Treatment

Preclinical Study Finds Pediatric Low-Grade Gliomas With CRAF Fusions May Require Differential and Combinatorial Targeted Therapies

Reported Hospitalization Rate in Patients Receiving Systemic Therapy for Metastatic NSCLC Much Higher in Real-World vs Clinical Trial Setting

Good Outcomes With Intensive, Interval-Compressed Chemotherapy and Irinotecan as Radiosensitizer in High-Risk Rhabdomyosarcoma

Most Women Undergoing BRCA Genetic Testing Do Not Receive Pretest Genetic Counseling

Improved Outcomes With Modified Docetaxel, Cisplatin, and 5-FU vs Standard Regimen Plus Growth Factor Support in Metastatic Gastric Cancer

Liquid Biopsy Promotes Precision Medicine by Tracking Patient's Cancer

Experimental Drug Shown to Prevent Neuroblastoma in Preclinical Study

Increasing Use of Preoperative Breast MRI Linked to Increased Postdiagnostic Imaging and Biopsy, Mastectomy, and Surgery Delay

PARP Inhibitor Olaparib Produces High Response Rate in Metastatic Prostate Cancer With DNA Repair Defects

Chemotherapy-Induced Hearing Loss Affects Cognition in Pediatric Brain Tumor Survivors

Protein CK5 a Marker for Cisplatin-Resistant Ovarian Cancer

ABC3: Patients Speak Out Against 'Damaging Messages' About Metastatic Breast Cancer, Call for Inclusion in Discussion About Treatment Costs

No Difference in Overall Survival, Poorer Relapse-Free Survival With Adjuvant Intermittent vs High-Dose Interferon Alfa-2b in Stage III Melanoma

ABC3: Higher Insulin Is an Independent Prognostic Factor in Advanced Breast Cancer

Lenalidomide Plus Rituximab Appears Promising as First-Line Therapy for Mantle Cell Lymphoma

Dexamethasone Reduces Pain Flare After Palliative Radiotherapy for Bone Metastases

Pooled Analysis Indicates That Low but Not High BMI Is Associated With Poorer Outcome in Metastatic Colorectal Cancer

Few Oncology Drugs Approved on Surrogate Endpoints Currently Have Evidence of Survival Benefit

Only 1 in 5 U.S. Patients With Pancreatic Cancer Gets Key Blood Test at Diagnosis

Study Shows Wide Variation in Costs to Treat Low-Risk Prostate Cancer

Phase III Trials Fail to Show Noninferiority of Surgical Outcome for Laparoscopic vs Open Resection in Rectal Cancer

No Reduction in Recurrent Colorectal Adenomas With Vitamin D and Calcium Supplementation

Breast Cancer Adjuvant Therapy Benefit Can Wax and Wane Over Time

Antiangiogenic Breast Cancer Treatment May Benefit Only Patients With Well-Perfused Tumors

No Significant Survival Improvement With Etirinotecan Pegol vs Physician’s Choice in Heavily Pretreated Advanced Breast Cancer

6-Year Incidence of Cardiac Events in NCCTG N9831/Alliance Adjuvant Trastuzumab Trial

Study Identifies Splicing Alterations That Enable Resistance to CD19 CAR T-Cell Immunotherapy

Researchers Discover SEC23B, Gene Associated With Cowden Syndrome, Contributes to Thyroid Cancer Risk

Stool DNA Test Accurate in Screening for Colorectal Cancer in Alaska Native People

Chemoradiotherapy Survival Benefit in Elderly Patients With Limited-Stage SCLC

Study Finds Tumor-Derived Exosomes May Predict Patients Likely to Develop Cancer Metastasis

American Cancer Society Report Finds Rising Rates of Breast Cancer Among African American Women, Especially in Southern States

Immunotherapy for Pancreatic Cancer Boosts Survival by More Than 75% in Preclinical Models

Exercise Could Provide a Margin of Safety for Women Who Want to Delay Preventive Mastectomy

Reduced Relapse but No Quality-of-Life Benefit With ATRA/Arsenic Trioxide vs ATRA/Idarubicin in Acute Promyelocytic Leukemia

29-Year Single-Center Longitudinal Experience Indicates 2% Annual Risk of Breast Cancer in Lobular Carcinoma in Situ

FDA Approves Adjuvant Ipilimumab to Reduce the Risk of Melanoma Returning After Surgery

Telotristat Etiprate Shows Clinical Benefit in Treating Carcinoid Syndrome in Cancer Patients When Added to Standard of Care

Newly Discovered Tumor-Suppressor Gene Affects Melanoma Survival

FDA Approves Talimogene Laherparepvec for Unresectable Recurrent Melanoma

To Optimize Tamoxifen Use Among Premenopausal Women With Breast Cancer, Include Access to Fertility-Preservation Options

Parabens May Increase Breast Cancer Risk at Lower Doses Than Previously Thought

Second-Line Lenvatinib Plus Everolimus Improves Progression-Free Survival vs Everolimus in Metastatic Renal Cell Carcinoma in Phase II Trial

Good Outcome With Neoadjuvant Chemoradiation and Local Excision in Clinical T2,N0 Distal Rectal Cancer

ASCO Calls for Comprehensive Payment Reform to Address Issue of Site Neutrality

ASTRO 2015: A Shorter Radiation Therapy Schedule Can Be as Effective as a Conventional Schedule for Men With Low-Risk Prostate Cancer

ASTRO 2015: Genomic Classifier Appears to Predict Metastasis in Patients With Prostate Cancer Following Prostatectomy

ASTRO 2015: Pediatric Patients With Ependymoma Have Favorable Outcomes With Immediate Postsurgical Radiation Therapy

ASTRO 2015: The Addition of 24 Months of Daily Antiandrogen Therapy Improves Overall Survival Following Recurrence After a Radical Prostatectomy

A Cancer Diagnosis Can Lead to Significant Loss of Working Hours, Income

National Coalition for Cancer Survivorship Honors Richard Pazdur, MD, and Ellen Goodman

Addition of Cediranib to Carboplatin/Paclitaxel Improves Progression-Free Survival in Metastatic/Recurrent Cervical Cancer in UK Phase II Trial

FDA Approves Trabectedin for Advanced Liposarcoma and Leiomyosarcoma

Risk-Based Approach to Guide Surveillance After Resection for Renal Cell Carcinoma

Statement From AACR CEO Margaret Foti, PhD, MD (hc), on Vice President Biden’s Call for More Cancer Research

ASTRO 2015: Hypofractionated Radiation Therapy May Be an Acceptable Treatment for Some Patients With Localized Prostate Cancer

ASTRO 2015: Patients With Intermediate-Risk Meningiomas Who Receive Postoperative Radiotherapy Have a 96% 3-Year Progression-Free Survival

ASTRO 2015: Androgen-Deprivation Therapy for 2 Years After Radiotherapy Improves Disease-Free Survival in Patients With Advanced Prostate Cancer

ASTRO 2015: Involved-Field Irradiation for Locally Advanced Esophageal Cancer Reduces Toxicity Without Increasing Locoregional Lymph Node Recurrence

How Physicians Communicate With Parents May Discourage HPV Vaccination of Adolescents

FDA Approves Liposomal Irinotecan for Advanced Pancreatic Cancer

ASTRO 2015: Frequent Post-Treatment Follow-up by Advance Practice Nurses Improves Care for Patients With High-Risk Head and Neck Cancer

ASTRO 2015: Image-Guided Intensity-Modulated Radiation Therapy Reduces Bowel Side Effects in Cervical Cancer Patients

ASTRO 2015: Coordinated Radiation Therapy and Palliative Care Based on Patient Feedback Lead to Better Quality of Life, Reduced Health-Care Costs

ASTRO 2015: Intensity-Modulated Radiotherapy Causes Less Inflammation Than 3D Conformal Radiotherapy in Lung Cancer Patients

NCCN Unveils Evidence Blocks for CML and Multiple Myeloma

Study Compares Maintenance Strategies After First-Line Oxaliplatin/Fluoropyrimidine/Bevacizumab in Patients With Metastatic Colorectal Cancer

American Cancer Society Updates Its Breast Cancer Screening Guidelines for Average-Risk Women

ASTRO 2015: Accelerated Partial-Breast Irradiation With Brachytherapy After Breast-Conserving Surgery Is as Effective as Whole-Breast Irradiation

ASTRO 2015: Patients With Bone Metastases Undergoing Radiation Therapy for Symptom Control Have Lower Pain Flare Rates With Steroid Use

ASTRO 2015: Reduced-Intensity Chemoradiotherapy May Be as Effective as Current Standard for Patients With HPV-Related Oropharynx Cancer

ASTRO 2015: Subset of Patients With Metastatic Melanoma Achieves Clinical Benefit From Combination of Immunotherapy and Radiation Therapy

Extended RAS Mutation Testing in Metastatic Colorectal Cancer to Predict Response to Anti-EGFR Antibody Therapy

Low-Dose CT Lung Cancer Screenings in 20 to 29 Pack-Year Smokers

Similar Pain Outcome With Ibandronate vs Single-Dose Radiotherapy for Localized Metastatic Bone Pain in Prostate Cancer

More Than 11 Moles on the Arm May Indicate Higher Risk of Melanoma

Inotuzumab Ozogamicin Receives FDA Breakthrough Therapy Designation for Acute Lymphoblastic Leukemia

Three-Gene Signaling Network Found to Have a Role in Neuroblastoma

Researchers Link Immunosuppressive Mycophenolate Mofetil to Increased Risk of Central Nervous System Lymphoma

Clergy Religious Beliefs Are Associated With Greater ICU Care in Congregants’ Final Days

Aggressive End-of-Life Care More Frequent Among Black Than White Men With End-Stage Prostate Cancer

Ibrutinib Produces Responses in Patients With Refractory Classic Hodgkin Lymphoma

Five-Gene Signature May Help Predict Survival Outcomes for Some Children With Rhabdomyosarcoma

Study Examines Links Between Viral and Bacterial Microbial Signatures and Triple-Negative Breast Cancer

Dactinomycin Produces Durable Response in Patient With NPM1-Mutant AML

Researchers Identify Dozens of Genetic Mutations Driving CLL and Their Evolution in Progression and Relapse

Anticancer Effects of Drugs Overestimated by as Much as 45% in Preclinical Animal Studies

Cancer Survivors More Likely to Have Poor Diets Than Those With No History of Cancer

Danish-Swedish Study Indicates No Survival Benefit of Routine Imaging for Diffuse Large B-Cell Lymphoma in Patients in First Complete Remission

Reduced Risk of Estrogen Receptor–Negative Breast Cancer With Later Age at Menarche in African American Women

Antioxidants May Increase the Rate of Metastasis, Protect Existing Tumors in Malignant Melanoma

Study Finds Use of Accelerated Partial-Breast Irradiation Has Stagnated

Evidence of Basal to Squamous Cell Phenotype Switch Under Vismodegib Treatment for Basal Cell Carcinoma

Adjuvant Hormone Therapy May Improve Survival in Epithelial Ovarian Cancer

Half-Matched Bone Marrow Transplant Recipients May Tolerate Transplantation Just as Well as Fully Matched Recipients

A Tolerant Immune System May Increase Cancer Risk

FDA Approves Use of Nivolumab in Advanced Nonsquamous Lung Cancer

12-Year Ipsilateral Breast Invasive Recurrence in 7.5% to 13.4% of Women With Low-Risk DCIS Receiving Surgical Excision Without Radiation

Alcohol Consumption Associated With Increased Cancer Risk in Countries at Different Economic Levels

Surgical Resection Prolongs Survival for Patients Whose Melanoma Has Spread to the Abdomen

Many Patients Do Not Accurately Recall Important Colonoscopy Details as Time Lapses

Therapeutic HPV-16/18 Vaccine Produces Regression of Cervical Intraepithelial Neoplasia Grade 2/3 in Phase II Trial

BMI Is an Independent Prognostic Factor in Patients With Node-Positive Breast Cancer Receiving Optimally Dosed Chemotherapy

Targeted Chemotherapy Shows Early Signs of Slowing Neuroblastoma Tumor Growth With Less Toxicity in Preclinical Models

Unilateral Mastectomy Is a More Cost-Effective Treatment for Sporadic Cancer in One Breast Than Contralateral Prophylactic Mastectomy

Comparison of Adjuvant Regimens in Early-Stage Breast Cancer

No Difference in Outcomes With Short-Course vs Longer-Course Radiotherapy in Elderly or Frail Patients With Newly Diagnosed Glioblastoma

Anti-CD19 Chimeric Antigen Receptor T-Cell Treatment Produces Response in Patient With Refractory Multiple Myeloma

All Relatives of Patients With Colorectal Cancer May Be at Increased Risk Regardless of Age at Diagnosis of Index Patient

Disparities in Outcomes for Children With Retinoblastoma May Suggest Unequal Access to Primary Care

FDA Approves Expanded Indication for Medical Device to Treat Newly Diagnosed Glioblastoma Multiforme

Palliative Care 2015: Panel Presents Recommendations to Improve Primary Palliative Care Services in Medical Oncology

Cardiovascular Prevention Trial Shows Reduction in Invasive Breast Cancer Risk With Mediterranean Diet Supplemented by Extra-Virgin Olive Oil

Palliative Care 2015: Collaboration Between Radiation Oncologists and Palliative Care Specialists Improves Care for Patients With Advanced Cancer

Palliative Care 2015: Study Finds the Answer to One Question Can Help Identify Patients Nearing the End of Life

Study Finds Cancer Is Increasingly Common in Patients With HIV, Necessitating Targeted Cancer Prevention Efforts

ASCO Endorses CHEST Guideline on Treatment of Small Cell Lung Cancer

Phase IIb Trial Shows Improved Progression-Free Survival With First-Line Aldoxorubicin vs Doxorubicin in Advanced Soft-Tissue Sarcoma

Telomerase Inhibitor Imetelstat Shows Activity in Myelofibrosis

Palliative Radiotherapy May Be Overused in Late-Stage Lung Cancer

Bariatric Surgery May Resolve Precancerous Uterine Lining Changes in Obese Women

FDA Grants Accelerated Approval to Pembrolizumab for Advanced NSCLC

Postprostatectomy Radiation Therapy Yields Low Toxicity and Favorable Patient-Reported Quality of Life

Nonmyeloablative Transplantation With High-Dose Cyclophosphamide May Improve Outcomes in Older Patients With Hematologic Malignancy

ECC 2015: Combination of Dabrafenib and Trametinib Superior to Vemurafenib Alone in Advanced Melanoma: Results of the COMBI-v Trial

Breast Tumor Genomic Characteristics Suggest More Aggressive Biology in African American vs White Women

ECC 2015: Pembrolizumab in Patients With Advanced Nasopharyngeal Carcinoma: Results of the KEYNOTE-028 Trial

ECC 2015: Atezolizumab in Locally Advanced or Metastatic Urothelial Carcinoma: Results of the IMvigor 210 Study

FDA Grants Accelerated Approval to Nivolumab in Combination With Ipilimumab in BRAF V600 Wild-Type, Unresectable, or Metastatic Melanoma

KW-0761 May Reduce Immune System–Suppressing Treg Cells in Patients With Solid Tumors

ECC 2015: Treatment of Elderly Patients With Breast Cancer Varies Throughout Europe

ECC 2015: Tackling the Global Shortfall in Radiotherapy

ECC 2015: Advanced Gastrointestinal Neuroendocrine Tumors and Results From the NETTER-1 Trial

ECC 2015: Lung and Gastrointestinal Neuroendocrine Tumors and Results From the RADIANT-4 Trial

Biomarker miR-506 Helps Predict Survival Time in Gastric Cancer Patients

Co-infection With High-Risk and Low-Risk HPV Reduces Risk of Squamous Cervical Cancer vs High-Risk HPV Alone

Tailored Education Improves Awareness of Risk for Therapy-Related Complications Among Childhood Cancer Survivors

Brentuximab Vedotin Effective, Safe in Elderly Hodgkin Lymphoma Patients Who Cannot Tolerate Standard Chemotherapy

ECC 2015: First Targeted Treatment for Small Cell Lung Cancer Shows Promise

ECC 2015: Children Exposed to Prenatal Cancer Treatment Show Normal Mental Processes and Heart Function

ECC 2015: Living Conditions and Gender Appear to Affect Incidence of Hodgkin Lymphoma

ECC 2015: Discovery of Differences Between Tumors of Younger and Older Patients With Colorectal Cancer May Lead to Better Treatments

ECC 2015: Genetic Screening of Brain Metastases Could Reveal New Targets for Treatment

Study Finds No Disease-Free Survival Improvement With Adjuvant Erlotinib in EGFR-Expressing NSCLC

Adding Bevacizumab to Treatment of Patients With NSCLC May Lead to More Toxicity but Less Risk for Hospitalization

ECC 2015: Hormone Therapy May Prevent Ovarian Failure and Preserve Fertility in Women With Breast Cancer

ECC 2015: Over Three-Quarters of People With Cancer Worldwide Have No Access to Safe Surgery

ECC 2015: Use of Aspirin Linked to Improved Survival in Gastrointestinal Cancers

ECC 2015: Childhood Cancers in Europe: Progress Has Been Made, but Much Still to Do

Study Finds Improving Cervical Cancer Screening Practice May Generate Health Gains With Nominal Increases in Cost

ECC 2015: Association Between Primary Surgery and Survival Benefit in Patients With Advanced Throat Cancers

ECC 2015: Nivolumab Improves Overall Survival in Patients With Advanced Kidney Cancer

ECC 2015: EUROCARE Results Show Large Variations in Survival Among European Countries

ECC 2015: Cabozantinib Improves Survival in Patients With Advanced Kidney Cancer

ECC 2015: Study Finds Significant Genetic Differences Between Breast Cancers That Relapse and Those That Do Not

Unprecedented Number of Mutations Identified in Rare Melanoma

Activity of Combined BRAF and MEK Inhibition in BRAF V600–Mutant Metastatic Colorectal Cancer

ECC 2015: Nivolumab Is More Effective Than Docetaxel in Extending Overall Survival in Advanced Nonsquamous NSCLC

Ruxolitinib-Capecitabine May Benefit Patients With Gemcitabine-Pretreated Metastatic Pancreatic Cancer With Systemic Inflammation

Phase II Study Suggests Survival Benefit With First-Line Fulvestrant vs Anastrozole in Advanced Breast Cancer

RAB35 Protein Implicated in Oncogenic Process in the PI3K/AKT Pathway

Adding Lenalidomide to Melphalan/Prednisone Yields Better Quality of Life Than Thalidomide in Elderly Patients With Multiple Myeloma

Patient Characteristics in Trials of Targeted Therapies for Metastatic Renal Cell Carcinoma Differ From Those in Real-World Population

Active Surveillance Program Improves Intermediate/Longer-Term Outcomes in Favorable-Risk Prostate Cancer

Ofatumumab Maintenance Improves Progression-Free Survival in Responders to Second- or Third-Line CLL Treatment

Preclinical Study Shows Starving Cancer Cells of Cholesterol May Inhibit Tumor Growth and Improve Drug Sensitivity

Breast Cancer Symposium: Recurrence Rates for Ductal Carcinoma in Situ Treated Between 1978–2010

Breast Cancer Symposium: Adjuvant Radiation After Lumpectomy May Benefit Some Elderly Women With Triple-Negative Breast Cancer

ASCO Statement: Recommendations for Obesity Clinical Trials in Cancer Survivors

Improved Progression-Free Survival With Trabectedin vs Dacarbazine After Conventional Chemotherapy in Advanced Liposarcoma or Leiomyosarcoma

FDA Approves New Oral Medication for the Treatment of Refractory Metastatic Colorectal Cancer

Decreased Mortality for Men With Unfavorable-Risk Prostate Cancer and Moderate or Severe Comorbidities Treated With Radiotherapy Alone

Study Questions Cost-Effectiveness of Universal BRCA Screening

Antifungal Agent Increases Risk of Cutaneous Squamous Cell Carcinoma in Some Lung Transplant Recipients

Phase III Trial Shows No Benefit of Adjuvant GM-CSF or Peptide Vaccine in High-Risk, Resected Melanoma

Study Finds CD38-Targeted Antibody Daratumumab Active in Relapsed Multiple Myeloma

Pancreatic Cancer Action Network and AACR Invite Applications for 2016 Research Grants

New Genetic Mutation Leading to Protein Repression Identified in Melanoma Cancer Cells

Prophylactic Surgery Rates Rise in Men With Breast Cancer

Study Explores Link Between MAPK Pathway Alteration and Long-Term Response to MEK Inhibitor in Serous Ovarian Cancer

Group-Based Behavioral Weight Loss Intervention Successful in Overweight/Obese Breast Cancer Survivors

Study Finds Racial Differences in BRAF/KRAS Mutation and Disease-Free Survival in Patients With Stage III Colon Cancer

Long-Term Remissions Reported in CLL Personalized Cell Therapy Trial

Researchers Discover Novel Marker for Retinoblastoma

Pembrolizumab Treatment May Cause Immune Cells to Express Markers of Reinvigoration

Long-Term Infusion of Immunotherapy May Reduce Pain in Children With High-Risk Neuroblastoma

Chemotherapy Pretreatment May Boost Effectiveness of CAR T-Cell Therapy in Patients With Lymphoma and Leukemia

Preclinical Study Shows Small-Protein Immunotherapeutic May Have More Antitumor Activity Than Conventional Antibodies

Frequency of Certain Immune Cells in Blood May Predict Response to Pembrolizumab in Metastatic Melanoma

Immune System–Boosting Agent May Reduce Early-Stage Melanoma Recurrences

Brazilian Wasp Venom May Be Active Against Cancer Cells

AACR’s Cancer Progress Report Details Major Advances in Cancer and Rising Costs of Treatment

Study Explores Link Between Allele Expression and Risk of Graft-vs-Host Disease in Transplant Recipients

Higher Failure-to-Rescue Rates in Lung Cancer Resections Reported at Hospitals With High Mortality Rates in Major Cancer Resections

Genetic Sequencing May Impact Treatment for Children With Rare, Aggressive Cancers

Statistical Model May Identify Patients Most Likely to Benefit From Mesothelioma Surgery

MicroRNA Panel Shows Early Potential as Biomarker of Pancreatic Precancers

Study Finds No Recurrence-Free Survival Benefit of Adjuvant Sorafenib in Hepatocellular Carcinoma After Resection or Ablation

Japanese Phase II Trial Shows Activity of Nivolumab in Platinum-Resistant Ovarian Cancer

Persistent Leukemia-Associated Mutations After Induction Therapy Predict Poorer Outcome in AML

Synchronous vs Sequential Tumor Resection in Patients With Advanced Colorectal Cancer

Study Explores Link Between Breast Cancer Recurrence Score and Chemotherapy Use

Trebananib Plus Sunitinib Active in Metastatic Clear Cell Renal Cell Cancer

BRAF Inhibition Successful in Relapsed/Refractory BRAF V600E–Mutant Hairy Cell Leukemia

ASCO Clinical Practice Guideline Update: Systemic Therapy for Stage IV NSCLC

WCLC: Cetuximab May Improve Survival in Some Patients With EGFR-Positive Squamous NSCLC

WCLC: New Study Reveals Genomic Architecture of EGFR Mutations in Lung Cancer

WCLC: Effect of EGFR Protein and EGFR Gene Copy Number in SQUIRE Trial

WCLC: Adding Bevacizumab to Chemotherapy Does Not Improve Overall Survival in Early-Stage NSCLC

WCLC: Smoking Cessation Reduces Mortality in Low-Dose Computed Tomography Screening Volunteers

Study Finds Nearly Half of Testicular Cancer Risk Is Inherited

FDA Grants Priority Review to Ixazomib for Patients With Relapsed/Refractory Multiple Myeloma

Internationally Acclaimed Cancer Researcher, Gianni Bonadonna, MD, Dies at 81

FDA Grants Alectinib Priority Review for ALK‑Positive Lung Cancer

New Agent Targeting Epigenetic Modifications Shows Activity in Advanced Cancer

Final Results of NO16968 Trial Show Improved Overall Survival With Adjuvant XELOX vs Bolus 5-FU/Leucovorin in Stage III Colon Cancer

WCLC: Results From ROMANA Trials of Anamorelin in Advanced NSCLC Patients With Cachexia

WCLC: IASLC Issues Statement on Tobacco Control and Smoking Cessation

WCLC: Bevacizumab Plus Standard Chemotherapy Improves Survival in Mesothelioma

WCLC: Impact of Time to Drug Approval on Potential Years of Life Lost

Improved Overall Survival With FOLFOXIRI/Bevacizumab vs FOLFIRI/Bevacizumab in First-Line Treatment of Metastatic Colorectal Cancer

Dose Equivalence Analysis Indicates Reduced Risk of Late Heart Failure With Daunorubicin vs Doxorubicin in Survivors of Childhood Cancer

BRAF V600 Mutation Appears to Be Targetable Oncogene in Some but Not All Nonmelanoma Cancers

Online Database Helps Organize Clinically Important Cancer Gene Mutations

Survivors of Childhood Cancer Have High Risk of Recurrent Stroke

Phase II Trial Shows Greater Activity With Lenalidomide/Rituximab vs Lenalidomide in Recurrent Follicular Lymphoma

Sham and Real Electroacupuncture Reduce Hot Flashes vs Gabapentin and Pill Placebo in Breast Cancer Survivors

Stiffer Breast Tissue in Obese Women May Promote Tumor Growth

Call for APOS 2016 Award Nominations

Combination of Chemotherapy and T-Cell Immunotherapy May Provide Novel Treatment Strategy for Glioblastoma

New 'Mutation-Tracking' Blood Test Could Predict Breast Cancer Relapse

AAV2 Virus May Be Linked to Hepatocellular Carcinoma in Patients With No History of Cirrhosis or Other Risk Factors

Increased Risk of Cancers After Age 40 in Childhood Cancer Survivors

Increased Risk of Intestinal Obstruction and Mortality in Survivors of Childhood Cancer

FDA Approves Rolapitant for Prevention of Chemotherapy-Induced Nausea and Vomiting

FDA Accepts for Priority Review the Biologics License Application for Elotuzumab for the Treatment of Relapsed Multiple Myeloma

High Use of Complementary or Alternative Medicines in Older Patients With Cancer

Pooled Analysis Shows Improved Outcomes With Continuous vs Fixed-Duration Therapy in Newly Diagnosed Multiple Myeloma

ASCO Releases Updated Policy Statement on Genetic and Genomic Testing for Cancer Susceptibility

Study Finds Modified CAR T Cells Can Selectively Target Solid Tumor Cells While Sparing Healthy Cells

Fertility Concerns and Side Effects Keep Many Young Women With Breast Cancer From Taking or Completing Tamoxifen

Pericytes May Help Some Tumors Evade the Immune System

Similar Outcomes With Tinzaparin vs Warfarin in Treatment of Acute Venous Thromboembolism in Patients With Active Cancer

Activity of Colony-Stimulating Factor-1 Receptor Kinase Inhibitor in Tenosynovial Giant Cell Tumors

Aspirin Reduces Obesity-Related Colorectal Cancer Risk in Patients With Lynch Syndrome

Integration of Mutation Status to FLIPI Improves Risk Stratification for Patients Receiving First-Line Immunochemotherapy for Follicular Lymphoma

Consolidative Radiotherapy Underused in Early‑Stage Diffuse Large B-Cell Lymphoma

Study Validates Method for Patient Reporting of Cancer Drug–Related Adverse Events

Black Women Have Higher Frequency of BRCA Mutations Than Previously Reported

Preclinical and Clinical Evidence of Lack of Sprouting Angiogenesis in Development of Lymph Node Metastases

Report of Secondary Outcomes in NSABP B-40 Indicates Improved Overall Survival With Neoadjuvant Plus Adjuvant Bevacizumab in Early Breast Cancer

Study Finds Many Women Experience Long-Term Psychosocial Consequences of False-Positive Screening Mammography

Beta-Blockers May Prolong Survival in Women With Ovarian Cancer

Longer Colonoscopies Linked to Lower Rate of Colorectal Cancer

Long-Term Use of Aspirin and Nonsteroidal Anti-inflammatory Drugs May Be Associated With Reduced Colorectal Cancer Risk

Patients With Fewer Than 50 Moles May Be at Risk for More Aggressive Melanoma

Imaging Probe May Be More Accurate Than the Best External Detector for Early Cervical Cancer Diagnosis

Introduction of Generic Aromatase Inhibitors Reduces Decline in Adherence in Medicare D Breast Cancer Patients Without Low-Income Subsidy

European Trial Indicates No Additional Benefit From Preoperative Radiotherapy Following Neoadjuvant Chemotherapy in Stage IIIA/N2 NSCLC

Study Identifies Genes Associated With Improved Survival for Patients With Pancreatic Cancer

Confocal Fluorescence Microscopy and Proflavine Staining May Speed Up Breast Cancer Diagnosis

Digital Gene Expression Cell of Origin Assay Shows High Prognostic Ability in Diffuse Large B-Cell Lymphoma

FDA Approves Eltrombopag for Pediatric Patients With Chronic Immune Thrombocytopenia

Study Evaluates Breast Cancer Mortality in Women With DCIS

Rolapitant Reduced Chemotherapy-Induced Nausea and Vomiting in Patients Receiving Highly Emetogenic Cisplatin-Based Chemotherapy

Rolapitant Reduced Chemotherapy-Induced Nausea and Vomiting in Patients Receiving Moderately Emetogenic Chemotherapy or Anthracycline/Cyclophosphamide

Danish Analysis Indicates Increased Risk of Late Adverse Outcomes in Patients Treated for Relapsed Disseminated Testicular Germ Cell Cancer

Black Women Less Likely Than Women of Other Races and Ethnicities to Survive Endometrial Cancer

Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Risk Assessment

Complete Resection of High-Grade Gliomas Yields Better Survival in Children, Especially Girls

Pembrolizumab Cutaneous Adverse Events May Predict Better Response

Adjuvant Taxane-Based Chemotherapy Is Not Associated With Increased Risk of Lymphedema, Study Finds

Analysis Indicates That Tubal Ligation Is Associated With Lower Endometrial Cancer Stage at Diagnosis and Improved Survival

Study Finds Music Therapy Lowers Anxiety During Surgical Breast Biopsies

Persistent HPV16 DNA in Post-Treatment Oral Rinse Associated With Poor Prognosis in HPV-Related Oropharyngeal Carcinoma

Similar Survival With Salvage Surgery After Definitive Chemoradiotherapy vs Neoadjuvant Chemotherapy Followed by Esophagectomy in Esophageal Cancer

Study Identifies Gene Mutations Associated With Aggressive Multiple Myeloma

Organ Transplant Recipients May Be More Likely to Develop Aggressive Melanoma

FDA Grants Regular Approval to Brentuximab Vedotin as Post-Transplant Consolidation Therapy for High-Risk Classical Hodgkin Lymphoma

Long-Term Results of Dutch CROSS Trial Indicate Continued Survival Benefit With Neoadjuvant Chemoradiotherapy in Esophageal Cancer

Study Reveals Effects of Chemoradiation in Brains of Glioblastoma Patients

Preclinical Study Shows MRI and Chemical Contrast Solution Combination Can Detect Breast Cancer Micrometastases

Higher Coffee Intake Associated With Significantly Reduced Cancer Recurrence and Increased Survival in Patients With Late-Stage Colon Cancer

Hypofractionation of Breast Radiotherapy Associated With Reduced Acute Toxicity

Most Stage-Specific Survival Improvement in Women With Breast Cancer Under Age 70 Is Not Explained by Tumor Size or Estrogen Receptor Status

Combining Interleukin-2 With Imiquimod and Topical Retinoid Therapy May Be Effective Against Cutaneous Metastatic Melanoma

Malaria-Causing Parasite May Contribute to Development of Burkitt Lymphoma

POLE-Mutant and Microsatellite-Unstable Endometrial Tumors May Be Candidates for Anti–PD-1 Treatment

Adding Oxaliplatin to Preoperative Chemoradiotherapy and Postoperative Chemotherapy Improves Disease-Free Survival in Locally Advanced Rectal Cancer

Identification of Risk Factors for Melanoma in Survivors of Non-Hodgkin Lymphoma

Researchers Identify Nerve-Guiding Protein That May Be Associated With Pancreatic Cancer Metastasis

Patients With Breast Cancer Over Age 80 Less Likely to Benefit From Chemotherapy Alone Than Younger Patients

International Myeloma Working Group Defines Revised International Staging System for Multiple Myeloma

Reduced Short-Term Effects With Hypofractionated Whole-Breast Irradiation After Breast-Conserving Surgery

French Phase II Trial Suggests No Benefit of Adding Bevacizumab to Paclitaxel in Advanced Angiosarcoma

Medullablastomas Can Be Classified Noninvasively at Diagnosis

Investigational Topical Gel Is Safe and Effective in Patients With Cutaneous T-Cell Lymphoma, Phase I Trial Shows

Susceptibility Gene Identified for Familial Nonmedullary Thyroid Cancer

Limited Resection Not Equivalent to Lobectomy for Survival in Older Patients With Early-Stage Lung Cancer

Clinical Scoring System May Help Identify Appropriate Colorectal Cancer Screening Methods

Oral Contraceptives May Offer Long-Term Protection From Endometrial Cancer

Annual Incidence of Melanoma Projected to Increase Markedly by 2030

Long-Term Survival in Ovarian Cancer May Be Better Than Expected in Some Patients

Key Genetic Factor in Cell Proliferation in Moles Identified

Study Finds Increased Short-Term Risk for Cardiovascular Disease Mortality After Chemotherapy for Testicular Nonseminoma

Study Identifies Genetic Mutations That Predict Response to Chemotherapy in Bladder Cancer

Addition of Docetaxel to Androgen-Deprivation Therapy Improves Survival in Metastatic Prostate Cancer

Packaging Paclitaxel in Nanoparticles May Increase Drug Efficacy in Preclinical Models

Delay in Treatment, Missed Diagnostic Testing Found Among Patients With Lung Cancer

Birinapant in Combination With Carboplatin May Be Effective Against Serous Ovarian Cancer

Proteins Found in Urine May Serve as Biomarker for Early-Stage Pancreatic Cancer

Sequencing Studies Show High Frequency of Actionable MET Mutations in Pulmonary Sarcomatoid Carcinoma

ASCO Statement: Improving the Evidence Base for Treating Older Adults With Cancer

17-Year Follow-up Indicates Early but Not Overall Reduction in Breast Cancer Mortality With Annual Mammography Screening at Age 40-49 Years

Researchers Identify Marker for Basal-Like Breast Cancer

Long Telomere Length Associated With Increased Lung Cancer Risk

Biomarker Signature May Predict Aggressive Disease in African American Men With Prostate Cancer

Involved-Field Radiotherapy May Be Best Option for Stage IA Nodular Lymphocyte-Predominant Hodgkin Lymphoma

ASCO Clinical Practice Guideline: Use of Biomarkers to Guide Decisions on Systemic Therapy for Women With Metastatic Breast Cancer

Benefit of Adjuvant Letrozole vs Tamoxifen Is Greater in Lobular Than in Ductal Breast Cancer

ASCO Clinical Practice Guideline Update: Recommendations for Using White Blood Cell Growth Factors

Pretreatment TNF Level May Be Associated With Memory Impairment in Women With Newly Diagnosed Breast Cancer

Researchers Identify Vital Gene for Preserving Gastrointestinal Health During Cancer Treatment

Fluorescent Imaging of Lung Lesions During Surgery May Localize Tumors and Improve Precision

Protein Imbalance in Akt Pathway May Trigger Cancer

No Difference in Overall Survival With Addition of Quinolone Derivative Vosaroxin to Cytarabine in Relapsed or Refractory AML

Study Finds Underinvestment in Long-Term Cancer Research

Intraperitoneal Plus Intravenous Chemotherapy—an Underused Strategy—May Improve Survival in Advanced Ovarian Cancer

Analysis Suggests Use of Pioglitazone for Diabetes May Increase Risk of Prostate and Pancreatic Cancers But Not Bladder Cancer

ERCC1 and Thymidylate Synthase Expression Identified as Promising Biomarkers in Metastatic Colon Cancer

Race and Institutional Support May Play a Role in Pharmacogenomic Trial Participation

Modified Mullerian-Inhibiting Substance Suppresses Growth of Some Recurrent Ovarian Tumors in Mouse Model

Improved Outcomes With Aromatase Inhibitors vs Tamoxifen in Early Breast Cancer

Adjuvant Bisphosphonates May Reduce Bone Recurrence and Breast Cancer Mortality in Postmenopausal Women

Genetic Test Predicts Colon Tumor Sensitivity to Radiation Therapy

Many Young Cancer Patients May Have Limited Awareness of Fertility Preservation Options

Dose-Escalated EBRT Yields Survival Benefit in Intermediate- and High-Risk but Not Low-Risk Nonmetastatic Prostate Cancer

Phase II Study Evaluates Neoadjuvant Eribulin vs Paclitaxel Followed by Doxorubicin/Cyclophosphamide in Locally Advanced HER2-Negative Breast Cancer

Study Finds Exercise in Adolescence Is Linked to Reduced Mortality From Cancer and All Causes in Later Life

NCIC MA.20 Trial: Addition of Regional Nodal Irradiation in Early Breast Cancer Improves Disease-Free but Not Overall Survival

EORTC Trial Shows Marginal Overall Survival and Significant Disease-Free Survival Benefit of Adding Regional Nodal Irradiation in Early Breast Cancer

Risk-Appropriate Therapies Now Commonplace in Prostate Cancer Treatment

Leukemia Renewal and Propagation Blocked by Inhibition of Surface Molecule

FDA Grants Orphan Drug Designation to Novel Dactinomycin Formulation for Ewing Sarcoma

Researchers Decode Molecular Action of Combination Therapy for Anaplastic Thyroid Cancer

Measurement of Intracellular and Extracellular Domain-Specific HER2 Expression May Predict Increased Benefit of Adjuvant Trastuzumab in Breast Cancer

Poor Survival in Patients With Multiple Myeloma Linked to Genetic Variation

ASCO Statement: A Conceptual Framework to Assess the Value of Cancer Treatment Options

Reduced Relapse but No Overall Survival Benefit With Adjuvant Lymph-Node Field Radiotherapy in High-Risk Melanoma

Omitting Doxorubicin From Postoperative Chemotherapy Has No Significant Survival Effect in Intermediate-Risk Wilms Tumor

Emergency Department Febrile Neutropenia Pathway for Patients With Cancer Reduces Time to Antibiotic Administration

County-Based Analysis Suggests Widespread Overdiagnosis of Breast Cancer in Mammography Screening

FDA Grants Breakthrough Therapy Designation to Lenvatinib for Metastatic Renal Cell Carcinoma

FDA Approves Carfilzomib Combination for Patients With Relapsed Multiple Myeloma

FDA Approves Sonidegib for Locally Advanced Basal Cell Carcinoma

Reemergence of Racial Disparity in Use of Adjuvant Chemotherapy in Stage III Colon Cancer

30-Year Study Shows Moderate Hormone Suppression May Be Sufficient in Thyroid Cancer

T-cell Receptor Therapy Achieves Encouraging Clinical Responses in Multiple Myeloma

Study Shows Palliative Chemotherapy in Patients With End-Stage Cancer Did Not Improve Quality of Life and May Be Harmful

No Survival Benefit of Adding MET Inhibitor Tivantinib to Erlotinib in Previously Treated Advanced Nonsquamous NSCLC

Early Lapatinib and Trastuzumab Active in HER2-Positive Metastatic Breast Cancer

Study Finds One-Third of Colorectal Cancers Diagnosed Before Age 35 Are Hereditary

New Analysis Points the Way to Earlier Diagnosis of Pediatric Chest Tumors

New Research Uncovers Key Molecule in Ovarian Cancer

Low Incidence of Infusion-Related Reactions Reported With 30-Minute Ipilimumab Infusion

Adding Neoadjuvant mFOLFOX6 After Chemoradiation May Improve Pathologic Complete Response Rate in Locally Advanced Rectal Cancer

Stanford Team Links Gene Expression, Immune System With Cancer Survival Rates

Trial Shows Molecular Subtypes of Diffuse Large B-Cell Lymphoma React Differently to Ibrutinib

Cancer Diagnosis Among Patients With Diabetes Reduced Adherence to Evidence-Based Diabetes Medications

German Study Shows Urea Cream Better Than Antioxidant Ointment in Preventing Capecitabine-Associated Hand-Foot Syndrome

No Progression-Free Survival Benefit of Adding VEGF Inhibitor Cediranib to First-Line Chemotherapy in Advanced Biliary Tract Cancer

‘Pill on a String’ Could Help Spot Early Signs of Esophageal Cancer

High-Volume Exercise Effectively Cuts Body Fat in Postmenopausal Woman, May Reduce Breast Cancer Risk

Aggressive Cancer Treatment Near End of Life Persists, Despite Rise in Advance Planning Efforts

No Benefit of Adding Gefitinib to Platinum-Based Doublet in EGFR-Mutant NSCLC After Progression on First-Line Gefitinib

Many Teens and Young Adults With Cancer Use Aggressive End-of-Life Measures

Study Identifies Mechanism Fueling Growth of Pancreatic and Prostate Cancer Cells

Circulating DNA and Protein Biomarkers May Be Associated With Benefit of Regorafenib in Metastatic Colorectal Cancer

FDA Grants Orphan Drug Designation to Melphalan for Cholangiocarcinoma

Adverse Event Reporting System Indicates Renal Toxic Effects With BRAF Inhibitors Vemurafenib and Dabrafenib

Psychosocial and Neurocognitive Impairment in Adult Survivors of Adolescent and Young Adult Cancer

High-Dose Chemoradiotherapy and Watchful Waiting May Be Alternative to Surgery in Some Patients With Distal Rectal Cancer

Noninvasive Prenatal Testing May Also Detect Some Maternal Cancers

Dietary Intervention May Prime Triple-Negative Breast Cancer for Targeted Therapy

Afatinib Improves Progression-Free Survival vs Erlotinib in Second-Line Treatment of Advanced Squamous Cell Carcinoma of the Lung

Combining MRI With Near-Infrared Spectral Tomography Increases Specificity in Breast Imaging

Study Links Leisure Time Sitting to Higher Risk of Specific Cancers and Total Cancer Risk in Women

Successful Preservation of Fertility After Aromatase Inhibitor Treatment and Ovarian Stimulation in Women With Breast Cancer

FDA Grants Orphan Drug Designation to Anti‑Tropomyosin Drug for Neuroblastoma

No Impact of Bleomycin and Vincristine Discontinuation on Efficacy of BEACOPP in Advanced Hodgkin Lymphoma

Belinostat Active in Relapsed/Refractory Peripheral T-Cell Lymphoma

DNA Repair Kinase Identified as Key Driver of Metastasis in Prostate Cancer

Smoking Cessation Near Time of Lung Cancer Diagnosis May Improve Survival

Study Finds Breast Cancer Survivors Gain More Weight Than Cancer-Free Women

Stereotactic Body Radiotherapy Yields Similar Outcomes in Patients With Biopsy-Proven vs Radiographically Diagnosed Early-Stage NSCLC

Meta-Analysis Indicates Benefit of Adjuvant Trastuzumab in Early HER2-Positive Breast Cancer With Small Tumors

Extended-Field Intensity-Modulated Radiation Therapy for Cervical and Endometrial Cancers Does Not Increase Risk of Duodenal Toxicity

Two-Thirds of Patients With Locally Advanced Laryngeal Cancer Not Receiving Recommended Treatment

Preclinical Studies Demonstrate Activity of Type II JAK2 Inhibitor in B-Cell ALL

FDA Approves Gefitinib for EGFR-Mutated Metastatic Non–Small Cell Lung Cancer

Disparities in Use of Breast-Conserving Therapy for Early-Stage Breast Cancer

Similar Long-Term Outcomes With Robotic vs Traditional Surgery in Patients With Bladder Cancer

Treatment With PI3K Inhibitors May Cause Cancers to Become More Aggressive and Metastatic

Diagnosis of Additional Small Breast Cancers Suggests Screening Mammography May Lead to Overdiagnosis

Early Study Suggests Which Glioblastoma Patients May Benefit From Dasatinib

DNA Shed From Head and Neck Tumors Detected in Blood and Saliva

Modeling Indicates Greater Benefit Without Greater Cost for Increased Colorectal Adenoma Detection Rate in Colonoscopy Screening

Early Relapse of Follicular Lymphoma After R‑CHOP Associated With Increased Mortality

Addition of Bevacizumab to Standard Chemotherapy Does Not Improve Overall Survival in Newly Diagnosed Ovarian Cancer

Breastfeeding Associated With Reduced Risk of Breast Cancer Recurrence and Mortality in Luminal A Subtype

Study Identifies Geographic Hot Spots With the Highest Colorectal Cancer Death Rates

Pembrolizumab Increases Progression-Free Survival vs Chemotherapy in Ipilimumab-Refractory Advanced Melanoma

Protein-Enriched Exosome Useful for Early Diagnosis of Pancreatic Cancer

Study Finds More Selective Ordering of Breast Biomarker Tests Could Save Millions in Health-Care Dollars

ASCO Endorses ASTRO Guideline on Radiation Therapy After Surgery for Endometrial Cancer

Phosphodiesterase Type 5 Inhibitors for Erectile Dysfunction Associated With Risk of Melanoma

Community-Based Trial Suggests No Benefit of Adding Thalidomide or Melphalan to Bortezomib-Based First-Line Treatment of Myeloma

Daratumumab Expanded Access Program Open to Eligible U.S. Patients With Heavily Pretreated Multiple Myeloma

Mapping Genetic Mutations in Cutaneous Melanoma

Risk Factors for Interval Invasive Second Breast Cancer

Earlier Palliative Care Consultation Associated With Cost Savings

Postoperative Radiation Therapy May Improve Overall Survival in Incompletely Resected Stage II or III NSCLC

ESMO World GI 2015: Second-Line Cetuximab Active Beyond Progression in Metastatic Colorectal Cancer

ESMO World GI 2015: Studies Confirm Regorafenib Benefit in Pretreated Metastatic Colorectal Cancer

Molecular Classification of Glioma Based on IDH Mutation, 1p/19q Codeletion, and TERT Promoter Mutation Status

Chinese Study Finds Serum MicroRNA Classifier Better Than Alpha-Fetoprotein for Early Detection of Hepatocellular Carcinoma

MASCC/ISOO 2015: Phase III Study of Single-Dose Fosaprepitant Dimeglumine in Prevention of Chemotherapy-Induced Nausea and Vomiting

Better Outcome With Paclitaxel vs Nab-Paclitaxel or Ixabepilone Plus Bevacizumab in First-Line Treatment of Advanced Breast Cancer

MASCC/ISOO 2015: Data Show Disconnect Between Clinician and Patient Perceptions of Treatment-Induced Nausea and Vomiting

Dutch Study Indicates No Survival Benefit of Adding Metformin to Gemcitabine-Erlotinib in Advanced Pancreatic Cancer

Phase II Trial Shows Activity of mTOR Inhibitor Ridaforolimus in Advanced Endometrial Carcinoma

Survival Benefit of Surgery Lower for Low-Grade vs Higher-Grade Ductal Carcinoma in Situ

ESMO World GI 2015: SENRI Trial Evaluates NK1 Antagonists for Emesis Prevention in Oxaliplatin-Based Chemotherapy

ESMO World GI 2015: Low Body Mass Index Associated With Poorer Survival in Metastatic Colorectal Cancer

Differences in Patient-Reported Outcomes but Not Global Quality of Life With Exemestane vs Tamoxifen in Early Breast Cancer With Ovarian Suppression

No Benefit of Adding CT to Basic Screening for Occult Cancer in Patients With Unprovoked Venous Thromboembolism

Development of New Blood Vessels Not Essential to Growth of Lymph Node Metastases

New Biomarkers Might Help Personalize Metastatic Colorectal Cancer Treatment

Low Axillary Recurrence/Mortality Among Older Women With Node-Negative Breast Cancer Undergoing Breast-Conserving Surgery Without Sentinel Node Biopsy

Four-Gene Model Predicts Response to Aromatase Inhibitor Therapy for Breast Cancer

Phase II Trial Indicates No Benefit of Sorafenib, Temsirolimus, or Bevacizumab Doublets vs Bevacizumab Alone in Advanced Renal Cell Carcinoma

Boosted Radiation Dose May Make Some Pancreatic Cancers Resectable

Immune Signaling Protein May Have Opposing Roles in Breast Cancer Development

Citrus Fruit Consumption May Be Linked to An Increased Risk of Melanoma

Phase II Study Shows Activity of Aurora A Kinase Inhibitor Alisertib in Relapsed/Refractory Peripheral T-Cell Lymphoma

Adding Everolimus to First-Line Trastuzumab-Paclitaxel Does Not Increase Progression-Free Survival in HER2-Positive Breast Cancer

Study Finds Current Prices of Hematologic Cancer Drugs Are Not Justified

Study Finds Significant Drop in New Prostate Cancer Diagnoses

Cardio-Oncology Services May Improve Patient Care if More Widely Available

ETV6 Mutation May Trigger Lymphoblastic Leukemia

No Significant Overall Survival Benefit With Second-Line Ramucirumab After Sorafenib in Advanced Hepatocellular Carcinoma

Study Finds Annual Low-Dose CT Screening Effective in Identifying Precancerous Lung Nodules

Long-Term Follow-Up of E1199 Trial Shows Maintained Benefit of Adjuvant Weekly Paclitaxel in Breast Cancer, Particularly Triple-Negative Disease

High Graft CD8 Cell Dose Predicts Improved Survival in Allogeneic Stem Cell Transplantation With Reduced-Intensity Conditioning

Importance of Establishing Definitions to Increase Survival After Blood/Marrow Transplant

Early Menarche May Play a Role in Development of Aggressive Breast Cancer in African American Women

Statin Use at Start of Androgen-Deprivation Therapy Increases Time to Progression During Androgen-Deprivation Therapy in Prostate Cancer

ASCO Publishes Conceptual Framework to Assess the Value of New Cancer Treatment Options

Transient Adverse Quality-of-Life Impact of Radiotherapy Added to Androgen-Deprivation Therapy in Locally Advanced Prostate Cancer

Chemotherapy May Be Preferred Option for Some With Advanced Prostate Cancer

Abdominal Blood Clots May Indicate Undiagnosed Cancer

Dabrafenib Plus Trametinib Improves Overall Survival vs Dabrafenib in BRAF V600–Mutant Melanoma

Increased Use of Nephron-Sparing Surgery in Older Patients With Small Kidney Cancers

Subset of Patients With Luminal A Breast Cancer May Not Benefit From Radiotherapy

National Cancer Data Base Analysis Indicates Survival Benefit of Adding Radiotherapy to ADT in Clinically Node-Positive Prostate Cancer

Whole-Exome Sequencing Identifies Biologically Informative Alterations in the Majority of Metastatic Cancers

Prenatal DDT Exposure Tied to Nearly Fourfold Increase in Breast Cancer Risk

ASCO 2015: Gene Therapy Paired With Traditional Surgical Resection Benefits Patients With Glioblastoma

National Cancer Database Analysis Identifies Characteristics of 10-Year Survivors of Pancreatic Ductal Adenocarcinoma

Large Survival Disparity Within 2 Years of Diagnosis for Black vs White Women With ER-Positive Breast Cancer

Lymph Nodes Signal More Aggressive Thyroid Cancer, Even in Young Patients

Assay Permits Rapid Molecular Characterization of Glioma

Single Dose of HPV-16/18 Vaccine May Prevent Cervical Cancer

Pooled Analysis Shows Similar Efficacy of Nivolumab in BRAF V600–Mutant and BRAF Wild-Type Advanced Melanoma

Long-Term Follow-Up Suggests No Detrimental Survival Effect of Dexrazoxane in Pediatric Patients With Leukemia or Lymphoma

Specific Mutations in KRAS Codon 12 Associated With Poorer Overall Survival in Patients With Colorectal Liver Metastases

Multicenter Study Redefines Brain Tumor Diagnosis and Treatment 

Latina Patients With Breast Cancer Need More Culturally Relevant, Language-Specific Stress Management Tools

Addition of Interferon Alfa-2b to MAP Does Not Meet Event-Free Survival Objective in Osteosarcoma With Good Response to Preoperative MAP

ASCO 2015: IMGN853 Demonstrates Single-Agent Activity for Patients With Platinum-Resistant Ovarian Cancer

Study Supports Early Intervention for Prostate Cancer Patients Who Experience Significant Emotional Distress

Study Finds ALK1 May Be a Therapeutic Target for Metastatic Breast Cancer

HPV Serum Antibodies May Predict Survival and Disease Progression in Patients With HPV-Positive Oropharyngeal Cancer

Colorectal Cancer Screening Increase May Reflect Affordable Care Act Provision

Denosumab Reduces Clinical Fracture Risk in Postmenopausal Women Receiving Aromatase Inhibitors

Study Shows Nearly 15 Million Women Live Prohibitively Far From Access to Gynecologic Cancer Care

Low Enrollment in Genomically Matched Clinical Trials After Genomic Testing

Need for Mental Health Services for Parents Who Lose a Child to Cancer

Investigators Identify Gene That Prevents Immune Response in Ovarian Cancer

Analysis Shows Advantage for Picture-Based vs Text-Based Warnings on Cigarette Packs

ASCO 2015: Glioblastoma Poliovirus Therapy Works Best at a Low Dosage

French Trial Shows Addition of Docetaxel and Estramustine to ADT Improves Relapse-Free Survival in High-Risk Localized Prostate Cancer

16-Gene Assay Recurrence Score Predicts Recurrence After Surgery for Localized Renal Cell Carcinoma

Livers Donated After Cardiac Death Are Safe to Use in Liver Cancer Patients

New Molecular Diagnostic Test Predicts Progression of Barrett's Esophagus to Esophageal Cancer

DNMT3A Mutations Predict Poorer Outcome in Younger Adults With AML Irrespective of NPM1 Genotype, but Type of Mutation Matters

Palbociclib Improves Progression-Free Survival in Advanced Hormone Receptor–Positive Breast Cancer

Study Examines Nerve Involvement in Cancer Pain

Pooled Analysis Shows Activity of Afatinib Differs in NSCLC According to Uncommon EGFR Mutations

Polymorphisms Related to Oxidative Stress Associated With Poorer Cognitive Function After Chemotherapy for Childhood ALL

Addition of Elotuzumab to Lenalidomide-Dexamethasone Improves Progression-Free Survival in Relapsed/Refractory Multiple Myeloma

Analysis Shows New Cancer Cases Rise Globally, but Death Rates Decline in Many Countries

Latest RTOG 0537 Data Indicate Electrical Nerve Stimulation May Provide Relief for Radiation-Induced Dry Mouth

Swedish Study Identifies Predictors of Discontinuing Adjuvant Hormone Therapy for Breast Cancer

Risk Algorithm Using Serial CA-125 Measurements Increases the Number of Screen-Detected Ovarian Cancers

Addition of Necitumumab to First-Line Gemcitabine-Cisplatin Improves Overall Survival in Stage IV Squamous NSCLC

Men With Asthma Less Likely to Develop Lethal Prostate Cancer

ASCO 2015: Patient Misconceptions Persist About Impact of Double Mastectomy on Survival

ASCO 2015: Study Supports IDH Gene as Prognostic Marker in Anaplastic Astrocytoma

Bronchial Gene-Expression Classifier Improves Bronchoscopy Performance in Diagnosing Lung Cancer

Addition of Bevacizumab to Radiotherapy and Temozolomide Does Not Worsen Health-Related Quality of Life in Glioblastoma Patients

Study Finds Prostate Cancer Survivors Who Maintained a Western Diet Had an Increased Risk of Death

ASCO 2015: New Targeted Treatment IMMU-130 Shows Activity in Patients With Metastatic Colon Cancer

Higher Tumor-Infiltrating Lymphocyte Level Associated With Better Outcomes in HER2-Positive Early Breast Cancer Independent of Neoadjuvant Treatment

ASCO 2015: Biomarker Analysis Reveals Several Potential Treatment Targets in Subtype of Anal Cancer

ASCO 2015: First Version of CancerLinQ™ Data Analytics Platform Debuts at Annual Meeting

ASCO 2015: Novel Targeted Drug Palbociclib Slows Progression of Hormone Receptor–Positive Breast Cancer

ASCO 2015: Anastrozole Offers Higher Breast Cancer–Free Interval Rates Than Tamoxifen Following Lumpectomy and Radiation for DCIS

Phase III Trial Confirms Benefit of Adding Bevacizumab to Chemotherapy in Chinese Patients With Advanced NSCLC

Addition of Number of Metastases Improves Prognostic Assessment Tool in Breast Cancer With Brain Metastases

ASCO 2015: Entolimod May Be a Promising Treatment Option for Many Solid Tumors

ASCO 2015: Economic Costs a Burden for Cancer Survivors

ASCO 2015: NCI-MATCH Trial Links Targeted Drugs to Genetic Abnormalities

ASCO 2015: Eribulin Extends Overall Survival for Heavily Pretreated Patients With Advanced Liposarcoma and Leiomyosarcoma

Oncolytic Immunotherapy With Talimogene Laherparepvec Improves Durable Response Rate in Advanced Melanoma

Adjuvant Regimen Produces Good Survival Results in Extrahepatic Cholangiocarcinoma and Gallbladder Carcinoma

ASCO 2015: Investigational ALK Inhibitor Demonstrates Promising Overall Response Rates in Patients With Advanced ALK-Positive NSCLC

ASCO 2015: ASCO Announces First-Ever Clinical Trial

ASCO 2015: Complete Lymph Node Dissection Does Not Improve Survival in Patients With Melanoma and Micrometastases

ASCO 2015: First Effective Adjuvant Chemotherapy for High-Risk, Localized Prostate Cancer

ASCO 2015: Phase III Study Confirms Benefits of Lenalidomide Maintenance Therapy for Patients With Multiple Myeloma

ASCO 2015: For Patients With Limited Brain Metastases, Adjuvant Whole-Brain Radiation Therapy Increases Cognitive Decline Without Improving Survival

ASCO 2015: Tumor Sequencing Study Highlights Benefits of Profiling Healthy Tissue

ASCO 2015: African Americans Prone to Display Negative Perceptions of Cancer-Related Clinical Trials

ASCO 2015: Reduction in Late Mortality Among Childhood Cancer Survivors Linked to Improvements in Cancer Care

ASCO 2015: Elective Neck Dissection Improves Early Oral Cancer Survival

ASCO 2015: Discussing Child’s Cancer Prognosis Beneficial for Parents

ASCO 2015: Phase III Study Finds Nivolumab Improves Progression-Free Survival, Especially When Combined With Ipilimumab, in Advanced Melanoma

ASCO 2015: Second-Line Afatinib Improves Overall Survival vs Erlotinib in Advanced Squamous Cell Carcinoma of the Lung

ASCO 2015: Removing More Breast Tissue Reduces by Half the Need for Second Cancer Surgery

ASCO 2015: Variations in Liver Cancer Attributable to Hepatitis Virus Variations

ASCO 2015: JAK Inhibitor Pacritinib Proves Effective for Easing Symptoms of Myelofibrosis

ASCO 2015: Obinutuzumab Doubles Progression-Free Survival in Patients With Relapsed, Indolent Non-Hodgkin Lymphoma

ASCO 2015: New Ibrutinib Combination Regimen Shows Substantial Benefits in Relapsed Chronic Lymphocytic Leukemia

ASCO 2015: First-in-Class Targeted Drug Daratumumab Is Effective as Single Agent in Heavily Treated Multiple Myeloma

ASCO 2015: Bevacizumab Combination Boosts Survival in Advanced Stomach and Esophageal Cancers

ASCO 2015: Melanoma Rates Dramatically Increasing in Children and Young Adults

ASCO 2015: Colorectal Cancer Genetically Different in Older and Younger Patients

ASCO 2015: Study Clarifies Best Treatments for Non–Clear Cell Kidney Cancers

ASCO 2015: Pembrolizumab Produces Clinically Meaningful Response in Patients With Recurrent or Metastatic Head and Neck Cancer

ASCO 2015: Nivolumab Extends Survival for Patients With Nonsquamous Non–Small Cell Lung Cancer

ASCO 2015: Nivolumab Shows Highly Promising Activity in Advanced Liver Cancer

ASCO 2015: Mismatch Repair Deficiency Predicts Response to Pembrolizumab Among Patients With Colorectal and Other Cancers

Very Overweight Teens May Double Their Risk of Bowel Cancer in Middle Age

Breast Cancer Subtype Incidence in the United States for 2011

Vismodegib Safety Profile in Long-Term ‘Real-World’ Use in Advanced Basal Cell Carcinoma

Blood Thinners Safe for Cancer Patients With Brain Metastases

Two Studies Highlight Benefit of Stereotactic Body Radiotherapy in Locally Advanced Pancreatic Cancer

Minority of Medicare Patients Have Adequate Cardiac Monitoring During Adjuvant Trastuzumab-Based Chemotherapy for Breast Cancer

Second-Line Dovitinib Shows Some Activity in FGFR2-Mutant and FGFR2-Nonmutant Advanced Endometrial Cancer

UK Trial Shows Neoadjuvant Platinum-Based Chemotherapy Noninferior to Adjuvant Chemotherapy in Advanced Ovarian Cancer

Study Links Paternal Age to Child’s Risk of Developing Blood and Immune System Cancer in Adulthood

Women With Inherited KRAS-Variant Mutation May Be at Increased Breast Cancer Risk Due to Acute Estrogen Withdrawal

More Than One-Third of Patients Diagnosed With Hepatocellular Carcinoma as Outpatients Have Diagnostic Delays

Regorafenib Improves Overall Survival in Asian Patients With Previously Treated Metastatic Colorectal Cancer

Hedgehog Inhibitor Sonidegib Active in Advanced Basal Cell Carcinoma

Multimodal Therapy Benefits Men With Prostate Cancer Experiencing Biochemical Recurrence After Local Therapy

First-in-Class Antibody Mixture Shows Clinical Activity Against Treatment-Resistant, Advanced Colorectal Cancer

Patients’ Desire for Rapid Notification of Skin Biopsy Results Leads to Preference for Phone Call Over In-Person Discussion

Pazopanib Plus Octreotide Active in Patients With Advanced Well-Differentiated Pancreatic Neuroendocrine Tumors

Obesity Poses Greater Prostate Cancer Risk for African American vs White Men

Polish Study Shows Inherited PALB2 Mutation Confers Greater Risk and Poorer Outcome of Breast Cancer

ASCO Releases Proposal for Payment Reform to Support Higher-Quality, More Affordable Cancer Care

Family History of Breast Cancer Doesn't Mean a Poor Prognosis for Women Who Develop the Disease

Omega-3 Fatty Acids and Placebo Reduce Aromatase Inhibitor–Related Musculoskeletal Pain in Early Breast Cancer

FDA Fast Track Designation Granted to AG-120 for Treatment of Patients With IDH1-Mutated Acute Myeloid Leukemia

Sacituzumab Govitecan Receives Fast Track Designation for Non–Small Cell Lung Cancer Therapy

Histologic Subtype Classification of Lung Adenocarcinoma Predicts Disease-Free but Not Overall Survival Benefit From Adjuvant Chemotherapy

AUA 2015: Studies Evaluate Effectiveness of Active Surveillance in Prostate Cancer Patients

AUA 2015: New Studies Call for Smarter Approach to Prostate Cancer Screening

AUA 2015: Sperm Banking Rates Increase With Fertility Counseling for Cancer Patients

Updated Meta-Analysis Confirms Survival Benefit of Adding Chemotherapy to Radiotherapy in Nasopharyngeal Cancer

German Trial Shows Reduced Risk of Venous Thromboembolism With Prophylactic Enoxaparin in Ambulatory Patients With Advanced Pancreatic Cancer

Improved Pathologic Complete Response Rate With Addition of Bevacizumab to Neoadjuvant Therapy in HER2-Negative Early Breast Cancer

Stereotactic Ablative Radiotherapy Achieves Better Overall Survival Than Surgery in Stage I NSCLC

Urine-Based Test Improves on PSA for Detecting Prostate Cancer

Breast Density Should Not Be the Only Criterion for Supplemental Breast Cancer Screening

American College of Physicians Offers Advice on High-Value Screening in Five Cancers

Physical Activity Programs Produce Benefits in Patients Receiving Adjuvant Therapy for Breast Cancer

Poorer Melanoma-Specific Survival With Stage ≥ T2b Tumors With NRAS or BRAF Mutation

Study Finds Noninvasive Colon Cancer Screening May Be Promising for African Americans

ASCO 2015: Experimental Immunotherapy Shows High Response Rate in Advanced Lung Cancer

Germline BRCA Mutations Found in Almost 5% of Patients With Pancreatic Adenocarcinoma

ASCO Provisional Clinical Opinion Update: HBV Screening for Cancer Patients Before Cancer Therapy

Nine-Valent HPV Vaccine Protects Against 80% of Cervical Cancers

Certain Treatments for Childhood Cancer May Increase Obesity Risk Later in Life

Combining Ixabepilone and Bevacizumab Appears Safe and Effective in Recurrent Uterine and Ovarian Cancers

Dutch Analysis Questions Breast Cancer Protective Effect of Salpingo-Oophorectomy in Healthy BRCA1/2 Mutation Carriers

Androgen-Deprivation Therapy May Lead to Cognitive Impairment in Prostate Cancer Patients

Study Shows Tomosynthesis Detects More Breast Cancers Than Traditional Mammography

Study Identifies Factors Contributing to Disparities in Cancer Treatment Based on HIV Status

TAS-102 Significantly Improves Overall Survival in Patients With Metastatic Colorectal Cancer

High Symptom Distress in Children With Advanced Cancer

Meta-Analysis Shows Increased Benefit of EGFR Tyrosine Kinase Inhibitors vs Chemotherapy in Subgroups of Patients With EGFR-Mutant NSCLC

ASCO 2015: Augmenting Standard Therapies Increases Cure Rates for High-Risk Wilms Tumor

ASCO 2015: Adding Chemotherapy to Initial Therapy Improves Survival in Patients With Advanced, Hormone-Naive Prostate Cancer

ASCO 2015: Oral Vitamin Reduces Risk of Common Nonmelanoma Skin Cancers in High-Risk Patients

ASCO 2015: Adding Elotuzumab Significantly Reduces Risk of Progression for Relapsed Multiple Myeloma

No Significant Difference in Outcome for ABVD Plus Radiotherapy vs Stanford V in Stage I or II Bulky Mediastinal Hodgkin Lymphoma

Increased Risk of Long-Term Pulmonary Dysfunction in Survivors of Childhood Cancer Who Received Pulmonary Toxic Treatments

Targeted Massively Parallel Sequencing Study Indicates Similarity of Somatic Driver Mutations in NSCLC for African American vs European Ancestry

Good Prognosis for Parenthood for Women Treated for Hodgkin Lymphoma During Childhood or Adolescence

Frequent Aspirin Use Reduces Risk of Cervical Cancer by Nearly Half

Preclinical Study Points to Possible Treatment for Lethal Pediatric Brain Cancer

Nilotinib Inferior to Imatinib in First-Line Treatment of Unresectable or Metastatic GIST

Cobas KRAS Mutation Test Receives FDA Approval

FDA Grants Fast Track Designation to Evofosfamide for Advanced Pancreatic Cancer

At-Risk Patients Often Opt Out of Comprehensive Multiplex Cancer Screening

Progress Made in Discovering Link Between Aspirin Use and Colorectal Cancer Prevention

CEP17 or TOP2A Aberrations Predict Benefit of Adjuvant Anthracycline-Based Chemotherapy in Breast Cancer

Donepezil Provides Modest Improvement in Cognitive Function Domains in Irradiated Brain Tumor Survivors

Maintenance Capecitabine-Bevacizumab Prolongs Time to Second Progression in Metastatic Colorectal Cancer in Dutch Trial

Weak Sunlight Exposure May Be a Risk Factor in Pancreatic Cancer

Two-Week International Diet Swap Shows Potential Effects of Food on Colon Cancer Risk

Hospital and Surgeon Factors Associated With Axillary Lymph Node Evaluation in DCIS

Immune Checkpoint Inhibitor Nivolumab Active in Heavily Pretreated Advanced NSCLC

New Study Finds Racial Differences in Survival Among Men With Breast Cancer

UK Trial of PET-Directed Therapy Suggests That No Radiotherapy May Be an Option in PET-Negative Early-Stage Hodgkin Lymphoma

Increased Lifetime Risk of Cardiovascular Disease for Patients Treated for Hodgkin Lymphoma as Adolescents or Adults

Oophorectomy Is Associated With Significantly Reduced Breast Cancer Mortality in Patients With BRCA1 Mutation or Estrogen Receptor–Negative Disease

ASCO Endorses ASTRO Guideline on External-Beam Radiotherapy for Patients With Locally Advanced NSCLC

Venetoclax Receives Breakthrough Therapy Designation in Relapsed/Refractory CLL With 17p Deletion

Population-Based Study Finds Patients With Gastrointestinal Tumors at Higher Risk of Other Cancers

Study Recommends Brain Cancer Patients Be Screened for Depression

Long-Term Use of Statins May Reduce Risk of Lung Cancer Death

Differing Patterns of Breast Cancer Risk After Hormone Therapy With Estrogen Plus Progestin or Estrogen Alone

Anti–PD-1 Antibody Pembrolizumab Improves Progression-Free and Overall Survival vs Ipilimumab in Advanced Melanoma

Multigene Panel Testing Provides Broader Information About Breast Cancer Risk

Surgical Interventions for Terminal Cancer Patients Remain Prevalent

Enzalutamide Improves Patient-Reported Outcomes and Time to Skeletal-Related Event vs Placebo in PREVAIL Trial

Long-Term Thyroid Hormone Replacement Associated With Decreased Colorectal Cancer Risk

Statin Use Not Associated With Reduced Mortality in Patients With Colorectal Cancer

EGFR Inhibitor Rociletinib Active in EGFR T790M Mutation–Positive NSCLC Previously Treated With EGFR Inhibitors

Nipple-Sparing Mastectomy as Safe as More Radical Procedures for Appropriate Patients

Bilateral Prophylactic Mastectomy Rarely More Cost-Effective Than Screening Mammography for High-Risk Women

Collaboration Between Surgeons and Medical Oncologists Improves Outcomes for Patients With Stage III Colon Cancer

American College of Physicians Releases Best Practice Advice for Cervical Cancer Screening in Average-Risk Women

Overnight Fasting May Reduce Breast Cancer Risk in Women

Safety of Autologous Stem Cell Transplantation Without Hematopoietic Support in Jehovah’s Witnesses With Hematologic Malignancies

Childhood Cancer Survivors More Likely to Claim Social Security Support as Adults

Addition of Nivolumab to Ipilimumab Improves Response Rate and Progression-Free Survival in Previously Untreated Advanced Melanoma

AZD9291 Shows Durable Responses in Patients With EGFR-Positive Lung Cancers

FDA Accepts Supplemental Biologics License Application for Nivolumab in Patients With Previously Untreated Advanced Melanoma

Phase II Study Shows Addition of Pazopanib to Paclitaxel Improves Progression-Free Survival in Platinum-Resistant/Refractory Advanced Ovarian Cancer

Two Studies Examine the Significant Postoperative Risk of Life-Threatening Blood Clots in Patients With Lung Cancer

Use of Radiotherapy After Prostate Cancer Surgery Declining, Despite Evidence of Benefit

Subgroup of Elderly Patients With Acute Myeloid Leukemia May Benefit From Initial Intensive Induction Chemotherapy

Conditional Survival Estimates After Resection for Intrahepatic Cholangiocarcinoma

Genomic Analyses Point to the Potential of Personalized Care for Liver Cancer Patients

Circulating Tumor DNA Is a Promising Biomarker for Progression in Diffuse Large B-Cell Lymphoma

Cancer Rates Significantly Increased Among Patients With Hepatitis C

Fallopian Tube Removal May Protect Premenopausal Women at High Risk for Ovarian Cancer From Some Surgical Side Effects

Addition of Ofatumumab to Chlorambucil Increases Progression-Free Survival in Previously Untreated CLL Patients Who Are Not Candidates for Fludarabine

No Improvement in Undetectable PSA Rate With Cixutumumab Plus Androgen-Deprivation Therapy in Metastatic Hormone-Sensitive Prostate Cancer

Single-Center Experience Indicates Relatively Good Prognosis After Allogeneic Stem Cell Transplantation Failure in CLL

FDA Approves Ramucirumab for Metastatic Colorectal Cancer

FDA Announces Clinical Trial Endpoints for Approval of Non–Small Cell Lung Cancer Drugs

Addition of Ramucirumab to Second-Line FOLFIRI Improves Overall Survival in Metastatic Colorectal Cancer

One-Third of Breast Cancer Patients Concerned About Genetic Risk

Crizotinib Receives Breakthrough Therapy Designation for the Treatment of ROS1-Positive Non–Small Cell Lung Cancer

AACR 2015: Study Identifies a Frequent Genomic Alteration in Pleomorphic Invasive Lobular Carcinoma

Eligible for Breast-Conserving Therapy, Many Still Choose Mastectomy

Association of Lipid Levels With Breast Cancer Risk in Women With Extensive Mammographic Density

More Extensive Lymph Node Clearance During Surgery for Esophageal Cancer May Not Improve Survival

AACR 2015: New Subsets of Lung Cancer With KRAS Gene Mutations Identified

Afatinib Improves Progression-Free Survival vs Methotrexate in Platinum-Treated Recurrent or Metastatic Head and Neck Cancer

U.S. Preventive Services Task Force Clarifies Mammography Recommendations for Women in Their 40s

Pretreatment PET Metabolic Tumor Volume Is Associated With Outcome in Stage III NSCLC

AACR 2015: New PARP Inhibitor Combination Shows Early Promise for a Wide Range of Cancer Patients

AACR 2015: Olaparib and Investigational PI3K Inhibitor BKM120 Combination Active Against Ovarian and Breast Cancer Subtypes

AACR 2015: Long-Term, Regular Aspirin Use Modestly Decreased Cancer Risk

AACR 2015: Subgroup of Men With Metastatic Prostate Cancer Respond to Olaparib Treatment

AACR 2015: Dual mTOR Inhibitor-Fulvestrant Combination Feasible, With Clinical Benefit for Advanced Breast Cancer Patients

AACR 2015: Metformin Use May Not Improve Pancreatic Cancer Survival

Study Examines Impact of Hospital Volume on Complication Rates in Patients Undergoing Robotic Prostate Surgery

Identifying Processes That Lead to Discontinuation of Chemotherapy for Patients With NSCLC at End of Life

Frequency of Germline TP53 Mutations in Patients With Early-Onset Colorectal Cancer Not Meeting Criteria for Li-Fraumeni Syndrome

AACR 2015: HPV Vaccine Provides Protection at Multiple Sites, Even Among Some Previously Exposed Patients

AACR 2015: Combining Two Investigational Immunotherapy Drugs Safe, With Early Signs of Effectiveness

AACR 2015: Black Women Found to Have Denser Breast Tissue Than White Women

AACR 2015: U.S. Breast Cancer Cases Expected to Increase by as Much as 50% by 2030

AACR 2015: Improved Responses With Ipilimumab-Nivolumab Combination vs Ipilimumab Alone in Advanced Melanoma

AACR 2015: Investigational PD-L1–Targeted Immunotherapy Safe for Patients With Triple-Negative Breast Cancer, Effective in Some

AACR 2015: Pembrolizumab Safe, With Signs of Clinical Benefit, for Patients With Malignant Pleural Mesothelioma

AACR 2015: New Immunotherapy Yields Long-Lasting Responses in Some Patients With Advanced Melanoma

AACR 2015: Investigational CART-meso Immunotherapy Feasible for Patients With Advanced Cancers

Obesity Significantly Increases Prostate Cancer Risk in African American Men

Excessive All-Cause and Second Primary Malignancy-Related Mortality and Frequent Late Morbidity in Hodgkin Lymphoma Patients Treated During Adulthood

Microscopic Melanoma Metastases in Less Radioactive Sentinel Lymph Nodes Pose Risk of Progression and Mortality

AACR 2015: New T Cell–Based Immunotherapy Shows Promise for Lethal Stem Cell Transplant Complication

AACR 2015: Pembrolizumab Is Better Than Ipilimumab for Advanced Melanoma in Phase III Trial

AACR 2015: Pembrolizumab Shows Promise in Non–Small Cell Lung Cancer

Glembatumumab Vedotin Appears Active in Heavily Treated Advanced Glycoprotein NMB–Overexpressing Breast Cancer and Triple-Negative Disease

Do Survival Gains Match More Intense Treatment in Younger Patients With Colon Cancer?

Cancer Experts Find Too Many People Are Being Screened, Diagnosed, and Treated for Disease

Evidence Grows That Melanoma Drugs May Benefit Some Lung Cancer Patients

One-Quarter of Advanced Lung Cancer Patients Tested for EGFR Mutations Started on First-Line Therapy Before Test Results Available

Circulating Tumor DNA May Be Used to Detect EGFR Mutations in Lung Cancer

Physical Activity Helps Cancer Survivors Fend Off Side Effects

Study Finds Large Disparities in Survival Among Adolescents and Young Adults With Differentiated Thyroid Cancer

Statin Use Is Associated With Reduced Risk of Primary Liver Cancer in Low-Prevalence Setting

Ibrutinib Is Highly Active in Previously Treated Waldenström’s Macroglobulinemia

Similar Outcomes With Laparoscopic vs Open Resection in Rectal Cancer

Patients With Relapsed or Refractory CLL Who Discontinue Ibrutinib Early Have Poor Outcomes

ASCO Issues Statement Praising the Senate Repeal of SGR

Less Than 95% Adherence to Mercaptopurine Maintenance Associated With Nearly Threefold Increased Risk of Relapse in Pediatric ALL

Circulating Tumor Cell Count and LDH Level as Patient-Level Surrogate for Survival in Metastatic Castration-Resistant Prostate Cancer

No Survival Benefit of Vorinostat in Progressive Advanced Malignant Pleural Mesothelioma

Study Finds Price of Cancer Drugs Varies Widely Based on Who’s Paying

Study Finds Link Between Muscle-Building Supplements and Testicular Cancer

Regional-Level Correlation of Inappropriate Prostate Imaging and Inappropriate Breast Imaging

Platinum Monotherapy Particularly Active in BRCA1/2-Mutant Metastatic Triple-Negative Breast Cancer

Neoadjuvant Iniparib Plus Gemcitabine-Carboplatin Is Active in Early Triple-Negative and BRCA1/2-Mutant Breast Cancer

Long-Term Study Shows Stress Management Techniques Improve Mood and Quality of Life for Breast Cancer Patients

Increasing Number of Boys Vaccinated Against HPV Could Protect More People at the Same Price

Complete Regression of Metastatic Cervical Cancer Is Observed After Treatment With HPV-Targeted Tumor-Infiltrating T Cells

Durable Responses With Nivolumab in Previously Treated Advanced Renal Cell Carcinoma

NPM1-Positive/FLT3-ITD–Negative Genotype Not Associated With Significantly Better Prognosis in Older AML Patients

Key Tumor-Cell Proliferation Mechanism Identified in Pediatric Bone Cancers

One in Five Medicare Patients With Melanoma Experience Surgical Delays

Study Finds Oncology Drug Pricing Models ‘Not Rational’

Stereotactic Body Radiotherapy Plus Cetuximab Appears Safe, Effective in Previously Irradiated Recurrent Head and Neck Squamous Cell Carcinoma

Worse Outcomes With Lapatinib vs Trastuzumab Plus Taxane in Advanced HER2-Positive Breast Cancer

Cancer Patients Lack Knowledge but Desire More Information on Radiation-Based Medical Imaging Tests

Risk of Breast and Ovarian Cancers May Differ by BRCA1/2 Mutation Type

Weak Relationship Between Surgical Oncologic Perioperative Morbidity and Publicly Reported Hospital Quality and Satisfaction Measures

Adjuvant Ipilimumab Increases Recurrence-Free Survival vs Placebo After Complete Resection of High-Risk Stage III Melanoma

FDA Grants Breakthrough Therapy Designation to Rucaparib in Advanced Ovarian Cancer With BRCA Mutations

Analysis Indicates Poorer Progression-Free and Overall Survival With Lower Baseline Vitamin D Levels in Follicular Lymphoma Patients

Persistence of HER2-Specific CAR T Cells in HER2‑Positive Sarcoma

Improved Quality Metrics for Robotic Pancreaticoduodenectomy With Increased Performance

Five-Year Analysis Indicates Potential for Long‑Term Survival With Ipilimumab Plus Dacarbazine in Advanced Melanoma

Erythropoietin Plus Radiation Therapy Does Not Improve Local-Regional Control in Anemic Patients With Head and Neck Cancer

Improved Progression-Free Survival With Brentuximab Vedotin Consolidation After Transplantation in Hodgkin Lymphoma

Nocturnal Cortisol Levels May Provide a Noninvasive Biomarker of Ovarian Cancer Severity

Study Identifies Racial and Ethnic Differences in Selecting Surgeons, Hospitals for Breast Cancer Care

Very Low Breast Density on Mammography Worsens Breast Cancer Prognosis

Substantial Pathologist Diagnostic Disagreement for Breast Biopsy Specimens

Asian Americans Have Better Cancer-Specific Mortality Than Non-Hispanic Whites

Low Use of Decision Aids for Localized Prostate Cancer by Radiation Oncologists and Urologists

Circulating Tumor DNA in Blood May Predict Recurrence in Patients With Diffuse Large B-Cell Lymphoma

Nivolumab Increases Response Rate vs Chemotherapy in Advanced Melanoma With Progression After Anti–CTLA-4 Treatment

New Study Reveals Effective Treatment Program for Breast Cancer Survivors With ‘Chemobrain’

Liver-Sparing Surgery Associated With Higher Survival Rates in Cancer Patients

Translocation t(11;14) Associated With Poorer Outcome in Bortezomib-Treated Newly Diagnosed Amyloid Light-Chain Amyloidosis

No Differences in Patient-Reported Outcomes or Resource Use With Early vs Delayed Initiation of Palliative Care Intervention

Reduced Family Caregiver Depression With Early vs Delayed Palliative Care Intervention for Caregivers

Overweight Girls Face Increased Risk of Colorectal Cancer Later in Life

Single Nucleotide Polymorphisms Associated With Colorectal Cancer Preventive Effect of Aspirin or NSAIDs in Persons of European Descent

Study Finds Both the Number of Childhood Cancer Survivors and the Prevalence of Morbidity Are Increasing

Gonadotropin-Releasing Hormone Agonist Treatment and Orchiectomy Linked to Increased Risk of Cardiovascular Disease in Men With Prostate Cancer

Intraperitoneal Chemotherapy Associated With Long-Term Survival Advantage Over Intravenous Chemotherapy in Advanced Ovarian Cancer

Experimental Immunotherapy Delays Recurrence for Stage III and IV Ovarian Cancers

Addition of Bevacizumab to Chemotherapy Extends Survival in Women With Platinum-Sensitive Recurrent Ovarian Cancer

Sentinel Lymph Node Mapping Identifies Positive Lymph Nodes in Women With High-Risk Endometrial Cancer

Italian Trial Shows Benefit of Dose-Dense Adjuvant Therapy With Sequential Epirubicin-Cyclophosphamide-Paclitaxel in Early Node-Positive Breast Cancer

Insufficient Awareness of Breast Density and Its Impact on Breast Cancer Detection and Risk

ASCP, CAP, AMP, and ASCO Issue Draft Colorectal Cancer Molecular Marker Testing Guideline, Announce Opening of Public Comment Period

Panobinostat and Carfilzomib Combination Appears Safe and Effective in Relapsed/Refractory Multiple Myeloma

Improved Outcome and Greater Use of Adjuvant Chemotherapy With Laparoscopic vs Open Colectomy in Nonmetastatic Colon Cancer

American Gastroenterological Association Releases New Guidelines on the Management of Asymptomatic Neoplastic Pancreatic Cysts

FDA Grants Priority Review to Carfilzomib Supplemental New Drug Application for Relapsed Multiple Myeloma

No Survival Benefit of IGF-1R/Insulin Receptor Inhibitor Linsitinib in Advanced Adrenocortical Carcinoma

Women With Diabetes More Likely to be Diagnosed With Advanced-Stage Breast Cancer

Younger Men Who Survive 10 Years After Radical Prostatectomy Are More Likely to Die of Non–Cancer-Related Causes

Low Nadir Testosterone in First Year of Hormone Therapy Linked to Improved Cause-Specific Survival and Delay of Hormone Resistance in Prostate Cancer

Elevated C-Reactive Protein Associated With Poorer Outcome in Melanoma

Smokers Have Twice the Risk of Prostate Cancer Recurrence After Surgery as Never-Smokers

Genome-Wide CRISPR Screen Provides Better Understanding of Tumor Evolution and Metastasis

No Improvement in Complete Remission Rate With Cytarabine Plus Amonafide L-Malate vs Daunorubicin in Secondary AML

Marked Increase in Fracture Risk in Patients Receiving Hematopoietic Stem Cell Transplantation

Study Compares Incidence and Severity of Treatment-Related Neuropathy in Patients With Colorectal Cancer vs Other Cancers

Effect of Smoking and Alcohol Consumption on Feeding Tube Duration in Head and Neck Cancer Patients

New Surgical Algorithm Results in Improved Complete Resection Rates in Advanced Ovarian Cancer

Decline in Proportion of Lung Cancer Patients Meeting Screening Criteria

PET-Adapted Sequential Salvage Therapy With Brentuximab and Augmented ICE Produces High Response Rate in Relapsed/Refractory Hodgkin Lymphoma

No Difference in Event-Free Survival With Stem Cell Transplantation Using Matched Unrelated vs Sibling Donor Grafts in Children With ALL

Experts Explore the Reasons Behind the High Cost of Cancer Drugs in America

Measuring Minimal Residual Disease Levels Proves to Be a Powerful Tool for Guiding Leukemia Treatment

European Retrospective Study Shows Activity of Crizotinib in Advanced Lung Adenocarcinoma With ROS1 Rearrangement

Addition of Lenalidomide to Docetaxel-Prednisone Worsens Survival in Chemotherapy-Naive Metastatic Castration-Resistant Prostate Cancer

Vegetarian Dietary Pattern, Particularly Pescovegetarian Pattern, Is Associated With Reduced Risk of Colorectal Cancer

Preliminary Study Reveals Gene Regulatory Path as Target for Aggressive Pediatric Brain Cancer

Study Finds U.S. Spends More on Cancer Care but Saves Fewer Lives Than Western Europe

Comprehensive Genomic Profiling Shows Distribution of Targetable Alterations in Carcinomas of Unknown Primary Site

Nivolumab Shows Activity in Advanced, Refractory Squamous NSCLC

Addition of Aprepitant to Ondansetron Effective in Preventing Chemotherapy-Induced Nausea and Vomiting in Pediatric Patients

Findings in Pooled Analysis of Long-Term Survival With Ipilimumab in Advanced Melanoma

New Breast Cancer Test Links Immune ‘Hotspots’ to Better Survival

NIH-Funded Study Suggests Novel Strategy to Improve Vaccine Efficacy in the Treatment of Glioblastoma

Clinically Distinct Subgroup of Childhood Secondary High-Grade Glioma Defined by BRAF Mutation and CDKN2A Deletion

Goserelin Provides Ovarian Protection During Adjuvant Chemotherapy for Breast Cancer

Breast Cancer Risk May Increase in Women Who Have First-Degree Relatives With a History of Prostate Cancer

International Lymphoma Radiation Oncology Group Issues Treatment Guidelines for Pediatric Hodgkin Lymphoma

Reduced Mammography Rates 3 Years After 2009 U.S. Preventive Services Task Force Guidelines Changes

Outcomes of Phase II Basket Trial of Molecular Profiling and Targeted Therapy in Advanced Thoracic Malignancies

Maintenance Sunitinib Improves Progression-Free Survival in Phase II Trial in Untreated Extensive-Stage Small Cell Lung Cancer

Chromosomal Rearrangement May Be the Key to Progress Against Aggressive Infant Leukemia

Substitution of Bortezomib for Vincristine in R‑CHOP Improves Progression-Free Survival in First-Line Therapy for Mantle Cell Lymphoma

EGFR L858R Mutation in Circulating Free DNA From Blood Samples of Patients With Non–Small Cell Lung Cancer Shown to Be Negative Prognostic Marker

Annual ASCO Report Shows Widespread Disturbance in Oncology Practice, Amid Growing Patient Demand and Administrative Burden

Significant Differences for Age of Diagnosis Between Blacks and Whites for Six Types of Cancer

Palliative Care Consultation Associated With Less Aggressive End-of-Life Care in Advanced Pancreas Cancer

NCCN Publishes New Guidelines for Smoking Cessation

Concurrent Chemoradiation Therapy at High-Volume Facilities Improves Survival for NSCLC

Thyroid Cancer Rare in Patients With Asymptomatic Benign Nodules

Left-Sided Primary Tumor Location More Common and Associated With Better Survival in Metastatic Colorectal Cancer

BRAF Wild-Type Melanomas During Dabrafenib Treatment for Metastatic BRAF V600E Melanoma

Study Finds Lycopene May Be Associated With Lower Risk for Kidney Cancer in Postmenopausal Women

Clinical Trial Suggests Temozolomide-Based Chemoradiation Is Best for Low-Grade Brain Tumors

Age-Stratified Predictive Model May Provide Surgical Guidelines for Uterine Leiomyomas

MRI Screening More Sensitive Than Mammography and Ultrasound for Familial Breast Cancer Irrespective of Age, Mutation Status, or Breast Density

Similar Local Recurrence Rates But Increased Distant Metastases With Adjuvant Localized vs Whole-Brain Radiotherapy in Patients With Brain Metastases

Factors in Ibrutinib Discontinuation in Patients With Chronic Lymphocytic Leukemia

Durable Responses at 3-Year Follow-up for CLL Patients Receiving Single-Agent Ibrutinib

Researchers Map Genomic Landscape of Childhood Adrenocortical Tumors for the First Time

No Benefit of Adding Bevacizumab to First-Line Gemcitabine-Docetaxel in Metastatic Uterine Leiomyosarcoma

Greater Guideline Adherence, Better Survival, Absence of Racial Survival Disparity Among Colorectal Cancer Patients in Integrated Health-Care System

New Analysis Reports Increased Risk of Thyroid Cancer After Breast Cancer Diagnosis

Addition of Orteronel to Prednisone in Metastatic Castration-Resistant Prostate Cancer Does Not Meet Overall Survival Endpoint in Phase III Trial

Simulation Study Based on ERSPC Data Shows Greatest Cost-Effectiveness With Two to Three PSA Screenings Between 55 and 59 Years of Age

Study Shows Targeting Cancer Cell ‘Cloak’ Could Benefit Drug Delivery

AACR Names Nancy E. Davidson, MD, President-Elect for 2015-2016

FDA Approves Dinutuximab Combination for Pediatric Patients With High-Risk Neuroblastoma

Neoadjuvant Chemotherapy for Breast Cancer Increases Chances of Lumpectomy, Decreases Chances of Mastectomy

Inherited Gene Variation Leaves Young Leukemia Patients at Risk for Peripheral Neuropathy

Complex Surgery Does Not Independently Predict Outcome in Advanced Ovarian Cancer

Acceptable Cardiac Safety of Ado-Trastuzumab Emtansine After Anthracycline-Based Chemotherapy in Early-Stage HER2-Positive Breast Cancer

Immunologic Factors Predict Pathologic Complete Response to Neoadjuvant Therapy With or Without Carboplatin in Breast Cancer

Colorectal Cancer Benefits With Flexible Sigmoidoscopy Screening in SCORE Trial Are Generalizable to Broader Population

New Study Assesses Inclusion of Family in Cancer Patients’ Treatment Decisions

Lower Household Net Worth and Black Race Associated With Nonadherence to Hormonal Therapy for Early-Stage Breast Cancer

Oral Bisphosphonate Use Reduces Risk of Postmenopausal Endometrial Cancer

FDA Approves First Biosimilar Product Filgrastim‑Sndz

Study Finds Websites That Market Personalized Cancer Care Services Overemphasize Benefits

Preclinical Study Shows Promise for the Development of Personalized Cellular Therapy for Brain Cancer

No Improvement in Overall Survival With Addition of Anti-EGFR Antibody Necitumumab to First-Line Pemetrexed-Cisplatin in Metastatic Nonsquamous NSCLC

Harold Varmus, MD, Stepping Down as Director of the National Cancer Institute

Aurora Kinase A Inhibitor Alisertib Active in Solid Tumors

FDA Approves Nivolumab to Treat Metastatic Squamous Non–Small Cell Lung Cancer

Early Study Shows Cabazitaxel May Be More Effective Than Docetaxel in Some Patients With Advanced Prostate Cancer

Meta-Analysis Shows Increased Risk of Ovarian Cancer With Menopausal Hormone Therapy

No Overall Survival Benefit of Adding Orteronel to Prednisone in Chemotherapy-Naive Metastatic Castration-Resistant Prostate Cancer

Decision Aid Including Information on Overdetection Increases Informed Choice in Breast Screening and Reduces Intention to Be Screened

Phase III Trial Shows Improved Survival With Long‑Term Androgen-Deprivation Therapy Plus High-Dose Radiotherapy in Localized Prostate Cancer

NRAS Mutations in Advanced Melanoma Correlate With Increased Benefit From Immunotherapies

Study Finds Immunohistochemistry Is More Effective Than FISH in Detecting EML4-ALK Rearrangments in Lung Cancer

CLEOPATRA Study: Significant Overall Survival Benefit of Adding Pertuzumab to Trastuzumab/Docetaxel in HER2-Positive Metastatic Breast Cancer

Study Finds Improved Survival for Young Patients With Brain Metastases Who Receive Stereotactic Radiosurgery Alone

Human Reovirus Formulation Receives FDA Orphan Drug Designation for Fallopian Tube Cancer

Adjuvant Chemotherapy Improves Survival in Patients With Locally Advanced Bladder Cancer

FDA Grants Breakthrough Therapy Designation to EBV-Targeted T Cells for Treatment of EBV-Associated Lymphoproliferative Disease

Novel Cell Profiling Technique May Help Personalize Cancer Treatments

Study Shows Lack of RNA Editing Leads to Melanoma Growth and Metastasis

Sipuleucel-T Demonstrates Sustained Immune Response 2 Years After Treatment in Biochemically Recurrent Prostate Cancer

Emergency Room Visits and Hospitalizations Are Common Among Women With Early Breast Cancer Receiving Chemotherapy

Prior Cancer Does Not Affect Outcomes Among Patients With Advanced Lung Cancer

Cost-Effectiveness Analysis of First- and Second-Line Bevacizumab Plus Chemotherapy in Metastatic Colorectal Cancer

Improved Prognosis for Patients With Estrogen Receptor–Positive Breast Cancer With Large Reductions in Mammographic Density After Tamoxifen Initiation

Active Surveillance of Intermediate-Risk Prostate Cancer Associated With Decreased Survival

Adjuvant Sorafenib and Sunitinib Do Not Improve Outcomes in Locally Advanced Kidney Cancer

Men Who Have Had Testicular Cancer May Be More Likely to Develop Prostate Cancer

Inconclusive Outcome for Lapatinib vs Trastuzumab Plus Capecitabine in Preventing CNS Metastases as First Relapse Site in HER2-Positive Breast Cancer

Early Evidence of Increase in Higher-Risk Prostate Cancers From 2011 to 2013

Androgen Receptor Abnormality May Not Be Associated With Primary Resistance to Taxane Chemotherapy

FDA Approves Panobinostat Combination for the Treatment of Multiple Myeloma

Lower 30-Day Mortality, Increased Likelihood of Chemotherapy With Laparoscopic vs Open Colectomy for Stage III Colon Cancer

Classic vs Rare EGFR Mutations in Non–Small Cell Lung Cancer Have Distinct Epidemiology, Clinical Implications

New Model Provides Improved Prediction of Breast Cancer Risk in African American Women

Final 8-Year Analysis of Intergroup Trial Shows Survival Benefit With Addition of Radiotherapy to Androgen-Deprivation Therapy in Prostate Cancer

Japanese Study Indicates Death at Home Is Better for Terminally Ill Cancer Patients

No Progression-Free Survival Benefit of Adding Bevacizumab to Endocrine Therapy in First-Line Treatment for Advanced Breast Cancer

Sensor Technology May Help Improve the Accuracy of Clinical Breast Exams

Axillary Ultrasound After Neoadjuvant Chemotherapy for Node-Positive Breast Cancer Could Reduce Sentinel Lymph Node False-Negative Rate

Patient Request/Demand for Clinically Inappropriate Intervention Uncommon in Outpatient Setting

Risk Assessment for Hodgkin Lymphoma Evolving, Promises Greater Precision and Specific Clinical Relevance

Improved TNM Prediction of Survival in HPV‑Related Oropharyngeal Carcinoma

Study Shows That Previous Cancer ‘False Alarms’ May Discourage Patients From Screening Future Symptoms

FDA Analysis Explores Relationship Between Response Rate and Survival at Trial and Patient Levels in Advanced NSCLC Studies

FDA Grants Cobimetinib Priority Review for Use in Combination With Vemurafenib in Advanced Melanoma

Chemotherapy Trials for Advanced Cancers of the Lung and Pancreas Overestimate Survival for Elderly Medicare Patients

FDA Approves Lenalidomide in Combination With Dexamethasone for Newly Diagnosed Multiple Myeloma

Adding Cetuximab to First-Line FOLFIRI Does Not Benefit Metastatic Colorectal Cancer Patients With RAS Mutations

‘Frailty Profile’ Predicts Survival and Toxicities Among Elderly Patients With Multiple Myeloma

Early Study Suggests Olaparib May Be Effective in Ovarian Cancers Expressing High Levels of POLQ

Genomic Classifier Score Identifies Risk of Metastasis and Benefit of Adjuvant Radiotherapy After Radical Prostatectomy

Reduction in Late Toxicities With Preoperative Image-Guided Radiation Therapy to Reduced Target Volume in Patients With Extremity Sarcoma

Survivors of Childhood Cancer at Risk for Developing Hormone Deficiencies as Adults

12-Year Study Suggests Procedures to Prevent Cervical Cancer Do Not Affect Fertility

Durable Remissions With Brentuximab Vedotin in Patients With CD30-Positive Relapsed/Refractory Diffuse Large B-Cell Lymphoma

No Difference in Anxiety or Health-Related Quality of Life in NHL Patients Receiving Rituximab Maintenance vs Retreatment at Disease Progression

Urea-Based Cream Prevents Sorafenib-Associated Hand-Foot Skin Reactions in Chinese Patients With Advanced Hepatocellular Carcinoma

Higher Folate Intake Associated With Reduced Risk of Hormone Receptor–Negative Breast Cancer in Premenopausal Women

FDA Approves Lenvatinib for Progressive Radioiodine-Refractory Differentiated Thyroid Cancer

TP53 Mutations Common in Pediatric Adrenocortical Carcinoma

Hypofractionated Radiotherapy Not Noninferior to Standard Radiotherapy in Acute Toxicity in Phase III Prostate Cancer Trial

ASCO Expresses Concern Over the New CMS Oncology Care Model

Use of Combined-Modality Therapy vs Chemotherapy Alone in Early Hodgkin Lymphoma Affected by Sex, Race, Distance to Treatment, and Insurance

Nutrient-Wide Association Study Shows Increased Coffee Intake May Be Associated With Lower Risk of Endometrial Cancer

Sunitinib Active in Platinum-Refractory Thymic Carcinoma

Lenvatinib Shows Promise for Patients With Radioiodine-Refractory Thyroid Cancer in Phase III Study

Japanese Phase III Trial Shows No Survival Benefit of First-Line Weekly Cisplatin/Docetaxel vs Docetaxel in Elderly Patients With Advanced NSCLC

Meaning-Centered Group Psychotherapy Improves Psychological Well-Being in Patients With Advanced Cancer

Scientists Identify Genetic Variations Linked to Treatment-Related Hearing Loss in Young Patients With Cancer

FDA Grants Orphan Drug Designation to Human Reovirus Formulation for the Treatment of Ovarian Cancer

Adding Sorafenib to Standard Therapy of No Benefit in Advanced Ovarian Cancer, Study Reveals

Study Identifies Eight Signs Associated With Impending Death in Cancer Patients

Higher Than Expected Incidence of Marrow Neoplasms after Adjuvant Therapy for Breast Cancer

Active Smoking Increases Mortality in Nonmetastatic Colorectal Cancer, Both Pre- and Postdiagnosis

Phase III Study Shows Significant Benefit of Obinutuzumab in Refractory Indolent Non-Hodgkin Lymphoma

ASCO Endorses American Cancer Society Prostate Cancer Survivorship Care Guidelines

New Approach to Colorectal Surgical Care Results in Shorter Recovery Times, Lower Costs

Widespread Use of Docetaxel Preceded Phase III Evidence of Usefulness in Patients With Metastatic Prostate Cancer

Reduced Use of Radiotherapy for Unresectable Pancreatic Adenocarcinoma in the United States

Overall Survival Analysis of LUX-Lung 3 and LUX-Lung 6 Indicates Improvement With Afatinib in Subgroup of EGFR-Mutant Lung Cancer

Interval Cancers Are More Aggressive in Nondense Breasts vs Screen-Detected Cancers

Women Who Undergo Delayed Breast Reconstruction May Experience More Cancer‑Related Distress Than Women Who Undergo Mastectomy Alone

Study Shows Immunosuppressives, Chemotherapy May Reactivate Hepatitis B

No Reduction in Quality of Life With Addition of Bevacizumab to Chemotherapy in GOG 240 Trial in Advanced Cervical Cancer

Genetic Screening Deemed Cost-Effective in
Non–Small Cell Lung Cancer

CMS Issues National Coverage Determination for Screening for Lung Cancer With Low-Dose Computed Tomography

Omitting Radiotherapy Ups Local Recurrence Risk in Older Women With Low-Risk Breast Cancer After Breast-Conserving Surgery and Endocrine Therapy

Patients With Detectable PSA After Radical Prostatectomy May Benefit From More Aggressive Radiotherapy, 10-Year Post-Treatment Analysis Shows

Analysis of Key Breast Cancer Genes Reveals Distinct Profiles for African American, European American Women

Phase II Study Shows Activity of Everolimus and Letrozole in Recurrent Endometrial Carcinoma

No Benefit of Panitumumab Plus Radiotherapy vs Cisplatin-Based Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma

No Benefit of Adding Panitumumab to Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma

Study Identifies New Pathway for Stalling BRCA-Mutated Tumor Growth in Mice and Human Cells

Vitiligo Predicts Improved Survival in Patients Receiving Immunotherapy for Stage III or IV Melanoma

Immune Gene Profile Strongly Associated With Benefit of Adjuvant Trastuzumab in HER2-Positive Breast Cancer

Evidence of Recurrence-Free, Disease-Free, and Overall Survival Benefit of Aspirin and COX-2 Inhibitors in Stage III Colon Cancer

FDA Approves Palbociclib in Combination With Letrozole for Advanced Breast Cancer

Study Sheds New Light on Syndrome Associated With Aggressive Pediatric Cancer

Dabrafenib May Stimulate Radioiodine Uptake in Patients With Iodine-Refractory Papillary Thyroid Cancer

ASCO Clinical Practice Guideline Update 2014: No Change to 2013 Venous Thromboembolism Prophylaxis and Treatment Guideline

Crizotinib Produces Systemic and Intracranial Disease Control in Patients With Advanced ALK-Rearranged NSCLC and Brain Metastases

Study Finds Biologic Markers Associated With High-Risk Pancreatic Lesions

FDA Grants Priority Review for Trabectedin for the Treatment of Patients With Advanced Soft-Tissue Sarcoma

FDA Grants Breakthrough Therapy Designation to MPDL3280A for Non–Small Cell Lung Cancer

California Primary Care Physicians Struggle to Adapt to Breast Density Law, Study Shows

Readmission After Major Cancer Surgery Associated With Discharge Destination and Length of Index Stay

Ruxolitinib Better Than Standard Therapy in Polycythemia Vera Patients With Inadequate Response to or Intolerance of Hydroxyurea

European Trial Indicates That Neither Dacarbazine Nor Bleomycin Should Be Omitted From ABVD Regimen for Early-Stage Favorable Hodgkin Lymphoma

Study Finds Metformin May Reduce Lung Cancer Risk Among Diabetic Nonsmokers

High-Risk Prostate Cancer Detection More Likely With Targeted MRI/Ultrasound Fusion Technique Than With Standard Biopsy

Prospective Cohort Study Indicates No Association Between Migraine and Breast Cancer Risk

Researchers Pinpoint Two Genes That Trigger Most Severe Form of Ovarian Cancer

Ibrutinib Active in Previously Untreated and Relapsed/Refractory CLL With TP53 Aberrations

Study Finds Fear of Cancer Can Be Either a Facilitator or Deterrent to Getting Colorectal Cancer Screenings

Inherited Gene Variation Helps Explain Drug Toxicity in ALL Patients of East Asian Ancestry

Protein-Based Therapy Shows Promise Against Resistant ALL in Preclinical Study

FDA Approves New Indication for Ibrutinib in Waldenström's Macroglobulinemia

Retrospective Study Indicates Improved Disease-Free Survival for Complete Mesocolic Excision vs Conventional Surgery for Colon Cancer

No Benefit of High- vs Standard-Dose Radiotherapy or for Addition of Cetuximab to Chemoradiation in Stage IIIA or IIIB NSCLC

Study Uncovers Range of Molecular Alterations in Head and Neck Squamous Cell Carcinomas, New Potential Drug Targets

Final Survival Analysis in COU-AA-302 Shows Benefit of Adding Abiraterone to Prednisone in Chemotherapy-Naive Castration-Resistant Prostate Cancer

Testosterone Therapy May Help Some Men With Castration-Resistant Prostate Cancer

Pre- and Postdiagnosis Physical Activity and TV Viewing Affect Overall Survival in Colorectal Cancer

Supplemental New Drug Application Submitted for Carfilzomib for Relapsed Multiple Myeloma

Age-Related Clonal Hematopoiesis Associated With Increased Risk of All-Cause Mortality, Heart Disease, and Stroke, as Well as Blood Cancer

RTOG 9804 Trial Shows Reduced Local Failure With Radiotherapy After Breast-Conserving Surgery in Patients With Good-Risk DCIS

Study Finds Many Women Lack Understanding of Their Breast Cancer, Especially Minority Patients

Clonal Hematopoiesis With Somatic Mutations Increases With Age and Increases Risk of Hematologic Cancer and Mortality

Analysis of Unexplored Part of Human Genome May Lead to Cancer Biomarker Development

New Breast Exam Nearly Quadruples Detection of Invasive Breast Cancers When Added to Screening Mammography in Women With Dense Breast Tissue

Sorafenib Plus Everolimus Shows Some Activity in Progressive Unresectable High-Grade Osteosarcoma

Genetic Diagnosis by Exome Sequencing Feasible for Familial Colorectal Cancer

No Utility of AJCC Stage IA vs Stage IB Designation in Breast Cancer

RTOG 9910 Trial Shows No Benefit of Longer Androgen Suppression Before Radiotherapy for Localized Prostate Cancer

Head and Neck Cancers in Young Adults More Likely to Be a Result of Inherited Factors

Researchers Identify Potential Treatment Targeting Proliferation Pathway in Some Aggressive Tumors

Long-Term Use of Hormonal Contraceptives Could Lead to Increased Risk of Brain Tumors

Entecavir Reduces HBV-Related Hepatitis and HBV Reactivation vs Lamivudine in Lymphoma Patients Receiving R-CHOP

No Survival Benefit of Adding Erlotinib to Sorafenib in Advanced Hepatocelluar Carcinoma

TP53 Mutations May Play a Role in Treatment‑Related Acute Myeloid Leukemia and Myelodysplastic Syndrome

Poor Health Status More Common Among Childhood Cancer Survivors vs Siblings, With Age‑Related Increase in Prevalence

Are Physicians Choosing Wisely When Imaging for Distant Metastases in Early-Stage Breast Cancer?

ATRX Mutation Linked to Brain and Pancreatic Neuroendocrine Tumors May Be Biomarker for Rare Adrenal Tumors

Sputum Biomarker Panel May Help Identify Which Patients With Lung Nodules Have Lung Cancer

Next-Generation Sequencing Uncovers Potential Genetic Drivers of Rare Breast Tumors

ASCO Announces Progress in the Development of CancerLinQ, With the First Version Due in Late 2015

Prime-Boost Vaccine Increases Survival in Metastatic Pancreas Cancer

ASCO Releases Annual Report on Progress Against Cancer and Names the Cancer Advance of the Year

Poor Geographic Accessibility of Advanced Cancer Clinical Trial Sites

Prolonged Sedentary Time Linked to Cancer and Other Health Risks Regardless of Exercise Habits

CPX-351 Receives Fast Track Designation for Secondary Acute Myeloid Leukemia in Elderly Patients

Addition of Linifanib to Carboplatin-Paclitaxel Increases Progression-Free Survival and Toxicity in Advanced Nonsquamous NSCLC

Low Sentinel Node Biopsy False-Negative Rate With Immunohistochemistry After Neoadjuvant Chemotherapy in Biopsy-Proven Node-Positive Breast Cancer

Two Combination Studies Demonstrate Safety and Survival Benefit for VT-122 in Liver and Pancreatic Cancers

Expanded Analyses of Phase III MM-398 NAPOLI-1 Study Substantiate Positive Results of MM-398 Combined With Fluorouracil/Leucovorin

Phase II and III Trials Support First-Line Panitumumab in Combination With FOLFOX in Wild‑Type RAS Metastatic Colorectal Cancer

Modified Pancreatic Cancer Regimen Maintains Effectiveness While Reducing Side Effects and Cost

Allogeneic Stem Cell Transplantation Prolongs Recurrence-Free Survival in NPM1-Mutant AML

Almost Half of Women Taking Tamoxifen for Primary Prevention of Breast Cancer Discontinue Use Before 5 Years

Selenium Supplements Following Diagnosis of Nonmetastatic Prostate Cancer May Increase Risk of Prostate Cancer Mortality

Study Identifies Signaling Pathway Responsible for Generating Slowly Proliferating, Chemoresistant Cancer Cells

Phase II Study Shows Activity of Paclitaxel Added to Trastuzumab/Pertuzumab in HER2-Positive Metastatic Breast Cancer

Breast Cancer Diagnoses and Survival Outcomes Vary by Race/Ethnicity

Study Finds Decreasing Rates of Primary Tumor Resection and Better Survival Among Patients With Advanced Colorectal Cancer

Metabolic Syndrome Linked With Higher Risk of Endometrial Cancer Regardless of Being Overweight or Obese

Use of Minimally Invasive Colorectal Cancer Surgery Increases at NCCN Centers, but Wide Variation Exists

Anamorelin Increases Lean Body Mass in Patients With Cancer Cachexia

Cognitive Behavioral Therapy Improves Insomnia After Cancer Treatment With No Difference in Combination With Placebo or Armodafinil

Adding Ziv-Aflibercept to FOLFIRI Results in Persistent Improvement in Overall Survival in Patients With Metastatic Colorectal Cancer

Revised Risk Classification for Pediatric Extracranial Germ Cell Tumors

Combining Newer, More Intensive First-Line Chemotherapy With Bevacizumab Improves Long-Term Outcome in Advanced Colorectal Cancer

Second-Line Ramucirumab Added to Standard Chemotherapy Improves Survival in Patients With Advanced Colorectal Cancer

Chemoradiation Plus Nonsurgical Management of Rectal Cancer Appears Safe, May Offer Better Quality of Life Than Surgery

Higher Vitamin D Levels Associated With Markedly Improved Survival in Patients With Advanced Colorectal Cancer

Many Cancer Survivors Have Unmet Physical and Mental Needs Related to Their Disease and Its Treatment

Long-Term Follow-up Shows Favorable Overall Survival Rates With Concurrent Neoadjuvant Chemoradiotherapy Regimens in Rectal Cancer

Thoracic Radiotherapy Benefits Patients With Extensive-Stage Small Cell Lung Cancer Who Responded to Chemotherapy

ASCO Endorses ESMO Guideline on Hereditary Colorectal Cancer Syndromes

Asian Cancer Survivors Report Poorer Care Communication and Care Quality

Oral Human Papillomavirus Infection More Likely to Persist in Older Men

Study Finds Whole-Genome Sequencing Is Successful in Identifying Patients’ Risk for Inherited Cancers

Nonoperative Management Should Be Used With Caution in Patients With Small Papillary Thyroid Tumors

No Benefit of COX-2 Inhibitor Apricoxib in Combination With Docetaxel or Pemetrexed in Second-line Treatment of Patients With Biomarker-Selected NSCLC

Low Prostate Cancer Mortality in Long-Term Follow-up of Canadian Active Surveillance Cohort

New Cancer Diagnoses Associated With Increased Risk of Stroke

No Association of Aromatase Inhibitor–Related Musculoskeletal and Vasomotor Symptoms With Relapse-Free Survival in NCIC CTG MA.27 Analysis

Increased Mastectomy Use in Patients With Early-Stage Breast Cancer

Chemotherapy Plus Targeted Therapy Reduces Recurrence in Women With Early-Stage HER2-Positive Breast Cancer

Management of Cancer Pain Has Improved but Remains Inadequate

Low-Level Laser Therapy May Reduce Limb Volume and Pain in Patients With Breast Cancer–Related Lymphedema

FDA Grants Fast Track Designation to SGX301 for First-Line Treatment of Cutaneous T-Cell Lymphoma

Institutional Experience Significantly Affects Overall Survival in Locally Advanced Head and Neck Cancer

Bispecific CD19-Directed CD3 T-Cell Engager Blinatumomab Active in Adults With Relapsed/Refractory B-Cell Precursor ALL

Changes in Temporal Patterns and Risk of Recurrence in Breast Cancer Between 1986–1992 and 2004–2008

Stereotactic Body Radiation Therapy Plus Chemotherapy Improves Survival Among Patients With Stage IV Lung Cancer

Radiation Plus Androgen-Deprivation Therapy Prolongs Survival for Older Men With Prostate Cancer

Palbociclib/Letrozole Improves Progression-Free Survival in First-Line Treatment of Estrogen Receptor–Positive/HER2-Negative Advanced Breast Cancer

Patients With Prior Cancer Excluded From Most Lung Cancer Trials

Somatic Tumor Neoepitopes as Basis for Response to CTLA-4 Inhibition in Melanoma

Scientists Discover the Role of Gene Mutations Involved in 75% of Glioblastomas and Melanomas

More Than 1.5 Million Cancer Deaths Averted During 2 Decades of Dropping Mortality

Exercise Improves Aromatase Inhibitor–Induced Arthralgia in Breast Cancer Survivors

Diabetes Increases Risk of Hepatocellular Carcinoma in All Racial/Ethnic Groups

Abstract ‘Spin’ Affects Interpretation of Trial Outcome

No Overall Survival Difference for Linifanib vs Sorafenib in Advanced Hepatocellular Carcinoma

Postdiagnosis and Pre-/Postdiagnosis Use of Bisphosphonates for Osteoporosis Reduces Risk of Skeletal Metastases in Women With Breast Cancer

Cancer Risk Associated With Lynch Syndrome PMS2 Mutation in European Cohort

Laparoscopic Surgery for Bladder Cancer Leads to Good Long-Term Cancer Control

FDA Approves Nivolumab for Advanced Melanoma

No Survival Difference for Adjuvant Capecitabine vs 5-FU With or Without Oxaliplatin in Stage III Colon Cancer

Worse Anxiety/Depression Symptoms in Patients Adopting ‘Helper’ Role in Breast Cancer Internet Support Group

American Psychosocial Oncology Society Issues Call for 2015 Award Nominations

Bisphosphonates May Help Prevent Endometrial Cancer

Addition of Hypoxia-Activated Prodrug TH-302 to Gemcitabine Improves Progression-Free Survival in Advanced Pancreas Cancer

Urinary PCA3 Adds to Predictive Models in Patients Presenting for Initial and Repeat Biopsy for Detection of Prostate Cancer

FDA Approves Companion Diagnostic for the Detection of BRCA1/2 Mutations in Ovarian Cancer

FDA Approves Olaparib to Treat BRCA-Mutated Advanced Ovarian Cancer

PD-1 Blockade With Nivolumab Produces High Response Rate in Relapsed/Refractory Hodgkin Lymphoma

Telephone Peer-Support Program Reduces Breast Cancer Distress for Women Carrying BRCA Mutation

Higher Levels of Physical Activity Improve Survival Among Men With Prostate Cancer

Targeted Next-Generation Sequencing Reveals a High Number of Genomic Mutations in Advanced Malignant Plural Mesothelioma

Study Identifies Mechanism Behind Genetic Abnormality That Accelerates Growth of Ewing Sarcoma

Induction Chemoradiotherapy Followed by Resection May Benefit Some Patients With NSCLC of the Superior Sulcus

High and Increasing 30-Day Hospital Readmission After Surgery for Advanced Ovarian Cancer in Medicare Population

First-Line Crizotinib Improves Progression-Free Survival vs Chemotherapy in ALK-Positive NSCLC

Long Noncoding RNAs Are a Novel Prognostic Marker in Older Patients With Acute Leukemia

Adding Ramucirumab to Pemetrexed and Chemotherapy Does Not Appear to Improve Progression-Free Survival in NSCLC

Characterization of Conditional Disease-Free Survival in Patients With Ovarian Cancer

Colon Cancer Gene-Expression Risk Scores Contribute Little to Prognostic Ability of Established Risk Factors

No Overall Survival Difference for Immediate vs Deferred Chemotherapy After Radical Cystectomy in Muscle-Invasive Bladder Cancer

Adjuvant Chemotherapy May Provide Survival Advantage in Patients With T1 Node-Positive Colon Cancer

FDA Approves Lanreotide Injection for Gastroenteropancreatic Neuroendocrine Tumors

Hypofractionated Whole-Breast Irradiation After Breast-Conserving Surgery Used in One-Third or Less of Eligible Patients

Racial Disparities in Colon Cancer Survival Linked to Advanced Disease and Comorbidities at Diagnosis

Germline SUFU Mutations Cause Gorlin Syndrome and Increase Risk for Childhood Medulloblastoma

SABCS 2014: BOLERO-3: Everolimus Plus Trastuzumab/Paclitaxel Misses the Mark in First-Line HER2 Advanced Breast Cancer

SABCS 2014: Fulvestrant Improves Survival Over Anastrozole for Patients With Advanced Breast Cancer

SABCS 2014: Oncotype DX DCIS Score Reliably Predicts Breast Cancer Recurrence in Patients With DCIS

SABCS 2014: Lowering Dietary Fat Intake Reduces Death Rates in Some Women With Breast Cancer

FDA Approves Ramucirumab Combination for Non–Small Cell Lung Cancer

High Frequency of Inherited Mutations in Susceptibility Genes in a Triple-Negative Breast Cancer Cohort Unselected for Family History of Breast Cancer

Modest Correlation of Progression-Free and Overall Survival in Modern First-Line Metastatic Colorectal Cancer Trials

SABCS 2014: Capecitabine Monotherapy Does Not Improve Survival in Elderly Patients With Early-Stage Breast Cancer

SABCS 2014: IBIS-I Trial Finds Tamoxifen Lowered Breast Cancer Rates Among High-Risk Women

SABCS 2014: Adding Carboplatin to Neoadjuvant Therapy Increases Pathologic Complete Response Rates Across Subtypes in Triple-Negative Breast Cancer

SABCS 2014: Ovarian Suppression Added to Hormonal Therapy Reduces Risk of Recurrence in Some Premenopausal Women

Nivolumab Shows Activity in Previously Treated Metastatic Renal Cell Carcinoma

SABCS 2014: Breast Cancer in Men and Women Has Different Biologic Characteristics and Outcomes

FDA Approves Nine-Valent HPV Vaccine for Prevention of Certain Cancers Caused by Five Additional Types of HPV

SABCS 2014: High Tumor Immune Cell Levels May Identify HER2-Positive Breast Cancer Patients Who Might Benefit From Chemotherapy Alone

SABCS 2014: Pembrolizumab Holds Promise in Breast Cancer, Early Studies Suggest

SABCS 2014: PI3K Inhibition With Pictilisib in Hormone Receptor–Positive Breast Cancer Not Ready for Prime Time

ASH 2014: Pracinostat Combination Shows Significant Clinical Activity in Phase II Study of Newly Diagnosed Acute Myeloid Leukemia

ASH 2014: Oral Inhibitor Shows Clinical Activity in Poor-Prognosis AML

ASH 2014: Common Genetic Variations May Contribute to Treatment-Related Cognitive Problems in Children With Leukemia

CDK7 Inhibitor Effective in Reducing Small Cell Lung Cancer in Preclinical Study

Anti-PD-L1 Antibody Shows Activity in Metastatic Urothelial Bladder Cancer

Survival Benefit of R-ACVBP vs R-CHOP in Diffuse Large B-Cell Lymphoma Attributable to Effect in Patients With Non–Germinal Center B-Cell–Like Tumors

ASH 2014: T-Cell Acute Lymphoblastic Leukemia Outcomes Excellent, Even for 'Poor-Risk' Group

ASH 2014: High Hopes for AG-221 in Advanced Leukemia

FDA Approves Denosumab for the Treatment of Hypercalcemia of Malignancy Refractory to Bisphosphonate Therapy

Daniel F. Hayes, MD, FASCO, Elected ASCO President for 2016-2017 Term

ASH 2014: Combination Therapy Shown to Be Effective for Patients With Myelodysplastic Syndrome and AML

ASH 2014: CD19-Directed CAR T-Cell Therapy Yields High Rate of Durable Remissions in Pediatric Acute Lymphoblastic Leukemia

ASH 2014: Ibrutinib Demonstrates Clinical Activity in Relapsed or Refractory Multiple Myeloma

ASH 2014: Pediatric Leukemia Treatment Regimens Lead to Improved Outcomes in Adolescents, Young Adults

ASH 2014: Blinatumomab Achieves Complete Molecular Responses in Majority of B-Cell Leukemia Patients

ASH 2014: PD-1 Blockade Moves Into Hematology

ASH 2014: Post-Transplant Brentuximab Vedotin Improves Progression-Free Survival in Hodgkin Lymphoma Patients

ASH 2014: HIV-Related Lymphoma Can Be Safely Treated With Autologous Hematopoietic Cell Transplant

ASH 2014: Strong Showing for Anti-CD38 Monoclonal Antibodies in Myeloma

ASH 2014: Carfilzomib-Based Triplet Yields ‘Unprecedented’ Duration of Remission in Relapsed Myeloma

‘Wound Response’ of Cancer Stem Cells May Explain Chemoresistance in Bladder Cancer

Intensified Chemotherapy Based on Tumor Marker Decline May Improve Progression-Free Survival in Patients With Poor-Prognosis Germ Cell Tumors

Cigarette Smoking Associated With Changes in Inflammation Markers

Telomere Length Genes Are Associated With Melanoma Risk

No Disease-Free Survival Differences Among Doxorubicin/Cyclophosphamide Plus Paclitaxel Regimens in High-Risk Early-Stage Breast Cancer

No Survival Difference but Greater Morbidity With Etoposide/Cisplatin vs Carboplatin/Paclitaxel With Concurrent Radiotherapy for Stage III NSCLC

Approximately 4% of New Cancers Worldwide Attributed to High BMI

FDA Approves Ruxolitinib to Treat Patients With Polycythemia Vera

Effect of Computer-Aided Detection in Mammography Screening on Cost and DCIS Diagnosis in Medicare Population

Ixazomib Receives Breakthrough Therapy Designation for Relapsed or Refractory Systemic Light-Chain Amyloidosis

Surveillance Guidelines Miss 30% of Renal Cell Carcinoma Recurrences After Nephrectomy

FDA Approves Blinatumomab to Treat Rare Form of Acute Lymphoblastic Leukemia

Bisphosphonates May Block the Development of HER-Driven Tumors, Preventing Breast, Lung, and Colon Cancers

DNA Vaccine Targeting Mammaglobin-A Produces Robust Immune Response in Metastatic Breast Cancer

Dacomitinib Shows Activity in First-Line Treatment of Patients With Clinically or Molecularly Selected Advanced NSCLC

RSNA Awards Gold Medal to Three Leaders in Radiology

Risk-Based Screening Misses Over 75% of Invasive Breast Cancers in Women in Their 40s

3D Mammography Improves Cancer Detection in Dense Breasts

CONCORD-2 Study Reveals Wide Variability in Global Cancer Survival Rates

Long-Term Diabetes Associated With Increased Mortality in Pancreas Cancer

Necuparanib Receives Fast Track Designation From the FDA for the Treatment of Metastatic Pancreatic Cancer

Despite Popularity of Alternative Medicine, Most U.S. Oncologists Do Not Discuss Herb and Supplement Use With Their Patients

Anti-CD19 Bispecific T Cell Engager Blinatumomab Shows Activity in Relapsed/Refractory B-Precursor ALL

FDG-PET Predicts Complete Response to Neoadjuvant Trastuzumab/Docetaxel in HER2-Positive Breast Cancer

FDA Grants Breakthrough Therapy Designation to Investigational CAR T-Cell Therapy

More Than 40% of U.S. Women Have Mammographically Dense Breasts

Addition of Vosaroxin to Cytarabine Demonstrates Antileukemic Activity in Relapsed or Refractory Acute Myeloid Leukemia

Benefit of Extended Rituximab Exposure in Poor-Prognosis Elderly Patients With Diffuse Large B-Cell Lymphoma

Low Risk of Breast Cancer After Ovarian Cancer in Women With BRCA Mutation

RTOG 0129 Long-Term Results: No Differences in Survival or Toxicity With Accelerated vs Standard Fractionation Plus Cisplatin in Head and Neck Cancer

FDA Warns Against Using Laparoscopic Power Morcellators to Treat Uterine Fibroids

Adult Survivors of Retinoblastoma Experience Few Cognitive or Social Setbacks

High-Dose Interleukin-2 Effective in Metastatic Renal Cell Cancer Pretreated With VEGF-Targeted Therapies

Cigarette Smoking Before Diagnosis of First Cancer Is Associated With Increased Risk of Second Cancers

Improved Overall Survival in Metastatic Melanoma With First-Line Dabrafenib Plus Trametinib

Two- vs One-Unit Cord Blood Transplantation Does Not Improve 1-Year Overall Survival in Children and Adolescents With Hematologic Cancers

Immune Checkpoint Inhibitors May Work in Brain Cancers

Advanced-Practice Nurse Telephone Counseling Improves Rate of Cardiomyopathy Screening in At‑Risk Adult Survivors of Pediatric Cancer

Novel Genomic Signature Predicts Postcystectomy Recurrence in High-Risk Bladder Cancer

Exposure to Hookah Smoke Doubles Benzene Uptake, Potentially Increasing Risk for Leukemia

No Overall Survival Difference for Amrubicin vs Topotecan in Second-Line Treatment of Small Cell Lung Cancer

FDA Approves Extended-Release, Single-Entity Hydrocodone Product With Abuse-Deterrent Properties

About 25% of Patients Undergoing Breast-Conservation Surgery for Stage 0 to II Carcinoma Have Subsequent Surgery

Interactions Between Genetic Variants and Sun Behaviors May Influence Future Melanoma Risk

Researchers Identify Biomarker of Response to New Ovarian Cancer Drug

PAM50 Risk of Recurrence Score Helps Predict Late Distant Recurrence After 5 Years of Endocrine Treatment for Breast Cancer

Nivolumab Improves Overall and Progression-Free Survival vs Dacarbazine in Previously Untreated Advanced Melanoma Without BRAF Mutation

Galeterone Shows Activity in Variant Form of Castration-Resistant Prostate Cancer

Patients With Advanced Papillary Kidney Cancer Respond Well to Bevacizumab/Erlotinib Combination Therapy

IDH1 Inhibitor Demonstrates Anticancer Activity in Advanced Leukemia

FDA Grants Orphan Drug Designation to BGB324 for Acute Myeloid Leukemia

RTOG Pooled Analysis Shows Good Long-Term Outcomes After Bladder-Preserving Combined-Modality Therapy for Muscle-Invasive Bladder Cancer

High Rate of Tumor Marker Assessment in Older Early-Stage Breast Cancer Survivors

Metabolic ‘Reprogramming’ by the p53 Gene Family Leads to Tumor Regression

Proton Radiotherapy Safe and Effective in Pediatric Rhabdomyosarcoma

Risedronate Reduces Anastrozole-Related Bone Loss in Osteopenic/Osteoporotic Postmenopausal Women

Briefer Biochemotherapy Yields Better Relapse-Free Survival but Greater Toxicity vs 1-Year High-Dose Interferon in High-Risk Melanoma

ASCO Calls for Major Medicaid Reform to Improve Quality Cancer Care for Low-Income Americans

BRAF V600E Mutation Predicts Recurrence of Papillary Thyroid Cancer

FDA Approves Bevacizumab Plus Chemotherapy for Platinum-Resistant, Recurrent Ovarian Cancer

Estimated Cost-Effectiveness of Low-Dose CT Screening for Lung Cancer

Outcomes With Lobectomy, Sublobar Resection, and Stereotactic Ablative Radiotherapy in Medicare Patients With Early-Stage NSCLC

No Benefit of Adding Iniparib to Gemcitabine/Carboplatin in Metastatic Triple‑Negative Breast Cancer

Gene Sequencing Projects Link Two Mutations to Ewing Sarcoma Subtype With Poor Prognosis

Good Results With Stereotactic Body Radiation Therapy Plus Erlotinib in Limited but Progressive Metastatic NSCLC

Oral Cancer–Causing HPV May Be Transmitted Through Oral and Genital Contact

Small Variation in Risk-Adjusted Hospital Readmission After Colorectal Cancer Surgery

Postdiagnosis Aspirin Use Associated With Reduced Disease-Specific Mortality Only in High-Risk Subgroup of Men With Nonmetastatic Prostate Cancer

HPV Vaccine Uptake Among Girls Is Lowest in States With Highest Rates of Cervical Cancer

Even With Equal Health-Care Access, Cancer Survival Rates Are Worse in American Indians and Alaskan Natives

Study Reports Improvement in Continence With Solifenacin After Radical Prostatectomy

End-of-Life Discussions Are Associated With Longer Survival and Higher Quality of Life

Continued Preventive Effect of Radiotherapy After Breast-Conserving Surgery for DCIS in 20-Year Follow-Up of SweDCIS Trial

Propensity Score–Matching Analysis Shows No Disease-Specific Survival Benefit of Sentinel Lymph Node Biopsy vs Observation in Head/Neck Melanoma

CMS Announces Proposed Decision to Cover Low-Dose CT Screening for Lung Cancer

Video-Assisted Thoracoscopic Surgery Technique for Pneumonectomy Shown to Be Safe

Combining Interleukin-2 With Gefitinib Increased Response Rates in Patients With Advanced Non–Small Cell Lung Cancer

Worse Patient-Reported Outcomes With Addition of Ovarian Function Suppression to Tamoxifen in Premenopausal Women With Breast Cancer

Greater Suppression of Intraprostatic Androgens by Adding Abiraterone to LHRH Agonist in Patients With Prostate Cancer

Olaparib Treatment Yields Promising Response Rates in Patients With BRCA Mutation–Associated Cancers

Number of Young Patients With Newly Diagnosed Colorectal Cancer Anticipated to Double

No Benefit of Adding Lapatinib to Fulvestrant in Hormone Receptor–Positive Advanced Breast Cancer

High Rate of Hepatitis B Reactivation in Chinese Patients Receiving Rituximab for Lymphoma

Comparable Disease Control, Less Morbidity With Axillary Radiotherapy vs Surgery in Breast Cancer Patients With Positive Sentinel Node

FOLFOXIRI/Bevacizumab Bests FOLFIRI/Bevacizumab in Metastatic Colorectal Cancer

Early Response to Dose-Intensive Chemotherapy Can Be Used to Tailor Subsequent Therapy in Pediatric Intermediate-Risk Hodgkin Lymphoma

Whole-Brain Radiation Therapy Plus Stereotactic Radiosurgery Improved Survival in Better-Prognosis Patients With Brain Metastases

Vigorous Exercise Lowers Risk of Cardiovascular Events in Adult Survivors of Childhood Hodgkin Lymphoma

Study Shows Integrative Medicine Can Relieve Pain and Anxiety for Cancer Inpatients

Ipilimumab/Sargramostim Improves Overall Survival vs Ipilimumab Alone in Patients With Advanced Metastatic Melanoma

Dual HER2 Blockade With Lapatinib and Trastuzumab Improves Inhibition of Tumor Growth in HER2-Amplified Uterine Serous Carcinoma

Shorter-Duration Therapy Including Lower-Dose Cyclophosphamide Preserves Efficacy in Newly Diagnosed Low-Risk Rhabdomyosarcoma

Wide Geographic Variation in Use of Laparoscopic Colectomy for Colon Cancer

CDC Reports That Millions of U.S. Women Are Not Getting Screened for Cervical Cancer

Good Long-Term Outcomes With Surveillance for Stage I Nonseminoma Testicular Cancer

New Guidelines Issued on Use of Complementary Therapies for Breast Cancer

FDA Approves Ramucirumab in Combination With Paclitaxel for Advanced Gastric or Gastroesophageal Junction Adenocarcinoma

Pelvic Radiotherapy May Benefit Some Women With Ovarian Clear Cell Adenocarcinoma

BRAF Inhibitor Dabrafenib Plus MEK Inhibitor Trametinib Improves Outcomes vs Dabrafenib Alone in Previously Untreated BRAF-Mutant Advanced Melanoma

BRAF Inhibitor Vemurafenib Plus MEK inhibitor Cobimetinib vs Vemurafenib Alone in Previously Untreated BRAF-Mutant Advanced Melanoma

Protein Linked With HPV-Positive Head and Neck Cancer May Lead to More Effective Therapies for the Disease

Absence of Residual Thrombosis After 6 Months of Low–Molecular Weight Heparin Indicates Low Risk for Recurrent Cancer-Related Deep-Vein Thrombosis

ASCO Endorses AUA/ASTRO Guideline on Adjuvant and Salvage Radiotherapy After Prostatectomy

Crizotinib Highly Active in ROS1-Rearranged NSCLC

Scoring to Predict Individual Risk of Heart Failure Among Childhood Cancer Survivors

Similar Local Tumor Recurrence Rates With Hypofractionated vs Conventional Radiotherapy for Ductal Carcinoma in Situ

Rewiring Cell Metabolism Slows Colorectal Cancer Growth

Gemcitabine-Based Treatment Yields Similar Response Rates, Less Toxicity Than DHAP Before Stem Cell Transplant for Relapsed/Refractory Lymphoma

Analysis Suggests 70-Gene Signature Strategy Is Not Cost-Effective in Adjuvant Decisions in Patients With Node-Negative Breast Cancer

Registry Data Reveals Sustained Local Control With Minimal Side Effects for Medically Inoperable, Early-Stage Lung Cancer Patients Receiving SBRT

Postoperative Radiation Therapy Improves Overall Survival for Patients With Resected Pathologic N2 Non–Small Cell Lung Cancer

Molecular Tumor Markers Could Reveal New Therapeutic Targets for Lung Cancer Treatment

Predictive Ability of CT Screen-Detected Nodule Volume, Diameter, and Volume-Doubling for Lung Cancer in NELSON Trial

Performance of Lung Cancer Low-Dose CT Screening With Increasing Screening Interval in NELSON Trial

Cancer Leaders Call for Congress to Act Quickly in 2015 to Reinvigorate Cancer Innovation in the United States

No Difference in Survival Rates in Patients With Lung Adenocarcinoma In Situ vs Minimally Invasive Adenocarcinoma

Medicare Costs Analysis Indicates Need for Decreasing Use of Biopsies as Diagnosis Tool for Lung Cancer

Patients at High-Risk for Lung Cancer Are More Likely to Receive Screening When Primary Care Provider Is Familiar With Guideline Recommendations

Oncology Advances Included in Cleveland Clinic's Top 10 Medical Innovations List for 2015

ALSYMPCA Subgroup Analysis: Radium-223 Survival Benefit Irrespective of Prior Docetaxel in Castration-Resistant Prostate Cancer With Bone Metastases

Higher Levels of Lecithin Retinol Acyltransferase Hypermethylation May Correlate With Earlier Stage of Colorectal Cancer

New Research Shows Association of Kidney Cancer With Use of Aristolochic Acid

Language and Communication Cognitive Complaints Worsen After Initiation of Endocrine Therapy in Early-Stage Breast Cancer

Topical Cidofovir and Imiquimod Active in Treating Vulval Intraepithelial Neoplasia

Increased Prediagnosis BMI Associated With Increased Risk of Second Obesity-Associated Cancers in Colorectal Cancer Survivors

CLEOPATRA Analysis Shows That HER2 Is Sole Marker Suitable for Selection of Pertuzumab/Trastuzumab-Based Treatment in Metastatic Breast Cancer

Survey Finds High Rates of Burnout Among Palliative Care Physicians, With Over 50% Predicted to Leave the Field in 10 Years

Chest Radiation to Treat Childhood Cancer Increases Patients’ Risk of Developing Breast Cancer

Long-Term Overall Survival Benefit of Adding Trastuzumab to Adjuvant Chemotherapy in Early-Stage HER2-Positive Breast Cancer

Overuse and Underuse of Recommended Imaging for Lung Cancer Staging in National VA Cohort

Single Nucleotide Polymorphisms in Thrombomodulin Gene Predict Mortality in Patients With Graft-vs-Host Disease

FDA Grants Breakthrough Therapy Designation Pembrolizumab in Advanced Non–Small Cell Lung Cancer

Low Mitotic Count Is an Independent Predictor of Survival in Women With Recurrent Uterine Leiomyosarcoma

Genomic Sequencing More Efficient in Predicting Breast Cancer Risk Than Previously Thought

No Progression-Free Survival Benefit of Dacomitinib vs Erlotinib Overall or in KRAS Wild-Type Disease in Pretreated Advanced NSCLC

No Survival Benefit With Pan-HER Tyrosine Kinase Inhibitor Dacomitinib vs Placebo in Pretreated Advanced NSCLC

Regional Hepatopancreaticobiliary Surgical Program Improves Care in VA System

Loss of Y Chromosome Associated With Higher Mortality and Risk of Cancer in Men

Higher Alkylating Agent Exposure Associated With Impaired Spermatogenesis in Adult Survivors of Childhood Cancer

Oral Rivaroxaban Has Efficacy Similar to Enoxaparin Plus Vitamin K Antagonist in Preventing Recurrent Venous Thromboembolism

Many Insured Patients Alter Their Lifestyles and Medical Care to Cope With Cancer Treatment Costs

One-Third of U.S. Cancer Survivors May Be Experiencing Financial or Work-Related Hardship

‘Smart Technology’ System for Home Hospice Symptom Management and Care Helps Both Patients With Cancer and Family Caregivers

Partnership Between Medical Oncologists and Palliative Care Specialists Improves Outcomes at an Inpatient Oncology Unit

First-Line FOLFIRI Improves Time to Treatment Failure and Is Better Tolerated vs ECX in Advanced Gastric Cancer

Blood Biomarker May Detect Lung Cancer

Newly Discovered Molecular-Level Mechanism May Increase the Growth of Breast Cancer Cells

14 Million Major Medical Conditions Attributable to Cigarette Smoking

Neoadjuvant Chemotherapy Plus Two Anti-HER2 Agents Optimal for HER2-Positive Breast Cancer

Personalized Genetic Risk Assessment Does Not Increase Colorectal Cancer Screening in an Average-Risk Population

Study Finds Increased Expression of NQO1 in Non–Small Cell Lung Cancer Patients With KRAS Mutations

ASCO Issues Clinical Expert Statement on Cancer Survivorship Care Planning

CD19-Directed CAR T Cells Produce Sustained Remission in Relapsed/Refractory ALL

TAS-102 Receives FDA Fast Track Designation for Refractory Metastatic Colorectal Cancer

Neratinib Plus Capecitabine Shows Activity in HER2-Positive Metastatic Breast Cancer

Increase in PSA Levels 5 to 10 Years After Prostatectomy May Not Signify Subsequent Development of Metastasis in Patient's Lifetime

Oncologist Participation in Tumor Board Meetings May Be Associated With Improved Outcomes for Patients With Lung or Colorectal Cancers

Medicare Part D Low-Income Subsidy Program Improves Adherence to Hormone Therapy After Breast Cancer Surgery

Death of Patients Within 1 Month of Cancer Surgery Influenced by Social and Demographic Factors

Having Dependent Children Motivates Parents With Advanced Cancer to Pursue More Aggressive, Life-Extending Treatments

FDA Grants Lenvatinib Priority Review Designation for Advanced Thyroid Cancer

FDA Approves Expanded Use of Tilmanocept for Lymphatic Mapping in Solid Tumors

Single-Day Education Program Mitigates Psychosexual Side Effects of Risk-Reducing Salpingo-Oophorectomy

Racial Differences in the Risk of Second Breast Tumors Reported in Women With Ductal Carcinoma in Situ

Substantial Benefit of Intensive Surveillance Following Bimodality Therapy for Esophageal Cancer

LINE-1 Hypomethylation Associated With Poorer Survival in Microsatellite Instability–High vs Microsatellite-Stable Tumors in Colorectal Cancer

ASCO Endorses Guideline for Molecular Testing to Select Lung Cancer Patients for EGFR and ALK Inhibitor Treatment

FDA Grants Priority Review to Palbociclib as First-Line Therapy in Combination With Letrozole in Advanced Breast Cancer

Researchers Reveal Genomic Diversity of Individual Lung Tumors

Hormone Loss Could Be Involved in Colon Cancer

Adding Aprepitant to Granisetron/Dexamethasone Reduces Chemotherapy-Induced Nausea and Vomiting After High-Dose Melphalan Conditioning in Myeloma

PET/CT Scanning May Provide Accurate Staging of Younger Patients With Breast Cancer

Second-Line Bevacizumab/Chemotherapy Improves Progression-Free Survival in Advanced HER2-Negative Breast Cancer

Rate of Cancer Detection at Risk-Reducing Salpingo-Oophorectomy

New Findings in Acute Promyelocytic Leukemia

Higher Levels of Cholesterol and Triglycerides May Increase the Risk of Prostate Cancer Recurrence

Blinatumomab Receives FDA Priority Review Designation in Acute Lymphoblastic Leukemia

FDA Approves Bortezomib Injection for Previously Untreated Patients With Mantle Cell Lymphoma

FDA Approves Netupitant and Palonosetron Combination Capsule for Chemotherapy-Induced Nausea and Vomiting

Study Finds Potential Link Between BRCA1/2 Mutations and Salivary Gland Cancer

New Predictive Model for Lung Cancer May Improve Accuracy in Prescreening Lung Nodules Prior to Resection

Improved Survival With Maintenance Capecitabine/Bevacizumab vs Bevacizumab Alone in HER2-Negative Metastatic Breast Cancer

New Mutations Found in Anaplastic Thyroid Cancer Lead to Dramatic Response and Acquired Resistance to Everolimus

Updated GEM2005 Trial Confirms Benefit of Melphalan/Bortezomib Combination in Elderly Multiple Myeloma Patients

Anti–PD-1 Antibody Pembrolizumab Is Active in Ipilimumab-Refractory Advanced Melanoma

Study Identifies Groups at Risk for Gastrointestinal Stromal Tumors

One in Three People With Cancer Has Anxiety or Other Mental Health Challenges

Overexpression of Threonyl tRNA-Synthetase Demonstrates Potential Value as a Prognostic and Therapeutic Factor in Ovarian Cancer Patients

HPV 16/18 Vaccine Shows Protective Efficacy in Women Aged > 25 Years in 4-Year Interim Follow-up of VIVIANE Study

Fiber-Based Laxatives Linked to Decreased Risk of Colorectal Cancer

After Adjustment for Stage at Diagnosis, No Difference Evident in Melanoma-Specific Mortality Between Amelanotic and Pigmented Melanomas

FDA Grants Orphan Drug Designation to DNX-2401 for Malignant Glioma

Adjuvant Radiotherapy Benefits Survival in Subsets of Patients With Node-Positive Prostate Cancer

Abiraterone Acetate/Prednisone in Metastatic Castration-Resistant Prostate Cancer: Final Analysis of Early-Access Protocol Study

2014 Nobel Prize in Physiology or Medicine Awarded to John O’Keefe, FRS, May-Britt Moser, PhD, and Edvard I. Moser, PhD

FDG-PET Is Less Specific in Diagnosing Lung Cancer in Areas With Endemic Infectious Lung Disease

AR-V7 in Circulating Tumor Cells Associated With Resistance to Enzalutamide and Abiraterone in Prostate Cancer

Increased Risk of Fracture After Radical Cystectomy and Urinary Diversion in Older Patients With Bladder Cancer

No Increased Risk of Ovarian Cancer With Perineal Powder Use

Study Finds Increase in Colonoscopy Rates Has Lead to Overuse

TERT Promoter Mutation Associated With Reduced Survival in Nonacral Cutaneous Melanoma

FDA Grants Orphan Drug Designation to Investigational Agent for Pancreatic Cancer

Comorbidity Associated With Shorter Overall Survival but Not With Time to Relapse or Toxicity in Older Women on Adjuvant Chemotherapy

Swedish Study Indicates No Increased Risk of Breast Cancer With 5 Years of Continuous Exposure to Calcium Channel Blockers

Enhanced Benefit Shown With FOLFIRI/Ziv-Aflibercept in Subset of Patients With Metastatic Colorectal Cancer

Researchers Discover Genetic Variant That Can Predict Aggressive Prostate Cancer at Diagnosis

FDA Grants Breakthrough Therapy Designation to AP26113 for ALK-Positive NSCLC

PET-CT as Standard for Response Assessment After First-Line Therapy in Follicular Lymphoma

Sex Steroid Hormones May Play a Role in the Development of Aggressive Prostate Cancer

Dutch Study Finds No Increased Risk of Cardiovascular Mortality in 5-Year Survivors of DCIS

Chemoradiotherapy vs Radiotherapy Alone Linked to Increased Risk of Subsequent Malignancies in Long-Term Survivors of Hereditary Retinoblastoma

Reduced Local Recurrence With Intensity-Modulated vs External-Beam Radiation Therapy in Primary Soft-Tissue Sarcomas of the Extremity

ESMO 2014: Abiraterone Plus Prednisone Significantly Improves Overall Survival in Chemotherapy-Naive Metastatic Castration-Resistant Prostate Cancer

Next-Generation HPV Vaccine May Prevent 90% of Cervical Cancer Cases Worldwide

PSA Bounce After Radiotherapy May Be Associated With Outcomes in Patients With Prostate Cancer

Proposed Comorbidity-Age Index in Prognostic Model for Allogeneic Hematopoietic Cell Transplantation

ESMO 2014: Everolimus Improves Overall Survival in Patients With Advanced Pancreatic Neuroendocrine Tumors

Cabozantinib Active in Pretreated Metastatic Castration-Resistant Prostate Cancer

Phase II Study Shows Activity of Hypoxia-Activated Alkylating Prodrug in Combination With Doxorubicin in Advanced Soft-Tissue Sarcoma

ESMO 2014: Nivolumab Shows Signs of Superior Response Rate Compared to Standard Chemotherapy in Advanced Melanoma

ESMO 2014: Lung Cancer Vaccine Fails to Improve Survival in Surgically Resected Non–Small Cell Lung Cancer

Robert S. Miller, MD, FACP, FASCO, Joins ASCO as Medical Director for Society's Institute for Quality

ESMO 2014: Phase III Study Confirms Regorafenib’s Survival Benefit in Metastatic Colorectal Cancer

ESMO 2014: BRAF/MEK Inhibitor Combinations Impressive in Melanoma Trials

Boost in Plasma Levels of Chain Amino Acids Is Associated With Increased Risk of Pancreatic Cancer

Study Finds Association Between Increased Esophageal COX-2 Expression and Barrett’s Esophagus, Obesity, and Smoking

ESMO 2014: Adding Cediranib to Chemotherapy Improves Progression-Free Survival in Metastatic or Recurrent Cervical Cancer

ESMO 2014: Afatinib Improves Progression-Free Survival in Advanced Head and Neck Cancer

ESMO 2014: Novel Oral Agent Treats Cancer-Related Cachexia in Non–Small Cell Lung Cancer

Aldoxorubicin Receives FDA Orphan Drug Designations for Glioblastoma, Small Cell Lung Cancer, and Ovarian Cancer

ESMO 2014: CLEOPATRA Study Shows ‘Unprecedented’ Survival With Dual HER2 Blockade in Metastatic Breast Cancer

Soy Intake May Adversely Affect Gene Expression in Early Breast Cancer

Subclinical Peripheral Neuropathy Is Common in Treatment-Naive Multiple Myeloma Patients, Correlates With Decreased Fingertip Innervation Density

Screening for and Treating Early-Stage Lung Cancer Is Less Costly Than Treating Late-Stage Disease

New ALK Inhibitor Alectinib Shows Activity vs Crizotinib-Resistant NSCLC

European Phase III Trial Suggests Benefit of Thoracic Radiotherapy in Extensive-Stage Small Cell Lung Cancer

Meta-Analysis Shows No Overall Survival Benefit of Six vs Fewer Planned Cycles of First-Line Platinum-Based Chemotherapy in Advanced NSCLC

FDA Grants Orphan Drug Designation to Bivalent Vaccine for Neuroblastoma

Continuous Lenalidomide/Dexamethasone Improves Progression-Free Survival in Transplant-Ineligible Patients With Myeloma

Pennsylvania Has High Rate of Increase in Thyroid Cancer, Including Advanced and Larger Tumors

Safe Integration of Surgical Innovations Essential to Patient Safety: Study Evaluates Minimally-Invasive Radical Prostatectomy

Clinical Trials Investigate Treatment Options for Precursor Diseases to Multiple Myeloma

Tyrosine Kinase Inhibitors May Improve Treatment Outcomes in Children With Philadelphia Chromosome–Like ALL

Pazopanib Maintenance Improves Progression-Free Survival in Ovarian Cancer, but Benefit Limited to Non–East Asian Patients

Patient Exhibits Involution of Eruptive Melanocytic Nevi on Combination BRAF and MEK Inhibitor Therapy

Preclinical Study Identifies Potential Drug Combination for Mantle Cell Lymphoma and Chronic Lymphocytic Leukemia

Pilot Study Evaluates Concurrent Use of Sunitinib and Radiation Therapy in Recurrent High-Grade Glioma

Preclinical Study Looks at RNA Polymerase I Inhibitor in Refractory AML and Multiple Myeloma

Adding Pan-Deacetylase Inhibitor Panobinostat to Bortezomib and Dexamethasone Improves Progression-Free Survival in Relapsed Myeloma

Search for Effective Regimens in Elderly Patients With Hodgkin Lymphoma

Major Depression Is Undertreated in Patients With Cancer

SMaRT Oncology-3 Trial Reports Collaborative Care Program Reduces Major Depression in Patients With Lung Cancer

Integrated Collaborative Care Program Highly Successful in Treating Major Depression in Patients With Cancer

Second-Line Ramucirumab Plus Paclitaxel Improves Overall Survival in Patients With Advanced Gastric Cancer

Lymphatic Mapping Agent Receives Orphan Drug Designation for Head and Neck Cancers

Para-Aortic Lymph Node Radiation Increases Risk of Diabetes in Hodgkin Lymphoma Survivors

PIK3CA Mutations Associated With Lower Rate of Pathologic Complete Response to Neoadjuvant Anti-HER2 Therapy in Breast Cancer

Male Pattern Baldness at Age 45 May Be Associated With Aggressive Prostate Cancer

Primary Site of Neuroblastoma Tied to Differences in Biologic, Clinical Characteristics, Including Survival

mTOR Inhibitor Ridaforolimus Shows Activity in Advanced Endometrial Cancer

Improved Outcomes in Myeloma With High-Dose Melphalan Plus Autologous Transplant and Lenalidomide Maintenance

Improved Survival with Adjuvant FOLFOX vs Fluorouracil/Leucovorin After Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer

Long-Term Colorectal Cancer Mortality After Removal of Adenomas

ASTRO: Analysis Finds Select Group of Stage IV Lung Cancer Patient Population Achieves Long-Term Survival After Aggressive Treatment

ASTRO: Good Primary Tumor Control, Positive 5-Year Survival Rates for Lung Cancer Patients Who Receive Stereotactic Body Radiation Therapy

ASTRO: Long-Term Androgen-Deprivation Therapy Plus High-Dose Radiation Therapy Improves Biochemical Control and Survival Rates in Prostate Cancer

Baseline Results of the UK Phase III ProtecT Trial of Active Monitoring, Radical Prostatectomy, or Radiotherapy for Localized Prostate Cancer

Study Identifies Two Novel ALK Mutations Causing Lung Cancer Resistance to ALK Inhibitors

Adding Cediranib to Olaparib Improves Progression-Free Survival and Increases Toxicity in Recurrent Platinum-Sensitive Ovarian Cancer

Anti-CD19 CAR T-Cell Treatment Effective in Chemotherapy-Refractory B-Cell Malignancies

ASTRO: Radiation Therapy Does Not Increase Risk of Lymphedema in Node-Negative Breast Cancer

ASTRO: Radiation Therapy Alone vs Chemoradiotherapy for Reducing Dysphagia in Advanced Esophageal Cancer

Little Molecular Difference and No Prognostic Effect of Clinical HER2 Status in Context of Intrinsic Breast Cancer Subtypes

AACR’s 2014 Cancer Progress Report Stresses Research Advances and More Federal Funding

ASTRO: Pretreatment Serum Levels of VEGF-A and TGF-β1 Predictive of Outcomes in Esophageal Cancer

ASTRO: Shorter Course of Androgen-Deprivation Therapy Yields Improved Quality of Life for High-Risk Prostate Cancer Patients

ASTRO: Radiation Therapy Improves Survival in Patients With Early-Stage Hodgkin Lymphoma

Genomic Analysis Reveals That a High-Risk Leukemia Subtype Becomes More Common With Age

No Significant Progression-Free Survival Benefit of Adding Ramucirumab to First-Line Docetaxel in Advanced HER2-Negative Breast Cancer

Increased Risk of Melanoma in Flight-Based Occupations

Modeling Study Critical of Intensive Colonoscopy Screening in Medicare Population

Partial Nephrectomy and Percutaneous Ablation for cT1 Renal Masses Produce Similar Rates of Local Tumor Recurrence

FDA Approves New Indication for Enzalutamide in Metastatic Castration-Resistant Prostate Cancer

Modeling Study Indicates Little Survival Difference With Contralateral Prophylactic Mastectomy in Breast Cancer Without BRCA Mutation

Racial/Ethnic Barriers to Breast Reconstruction After Mastectomy for Breast Cancer

Baseline Vitamin D Not Associated With Survival in Patients With Advanced Pancreatic Cancer in CALGB 80303/Alliance Trial

ALK Rearrangements Are Associated With Improved Outcomes in Patients With Non‒Small Cell Lung Cancer and Brain Metastases

No Benefit of Adding Cetuximab to Cisplatin and Accelerated Radiotherapy in Stage III or IV Head and Neck Carcinoma

Olaparib Tablet Found Safe and Effective in Heavily Pretreated Patients With Ovarian Cancer

Radiation Therapy With Concurrent Chemotherapy After Surgery Is an Effective Treatment for High-Risk Endometrial Cancer

ASCO and Cancer Care Ontario Release Clinical Practice Guideline for Systemic Therapy in Men With Metastatic Castration-Resistant Prostate Cancer

National Lung Screening Trial Analysis Finds Low-Dose CT Screening Identifies More Lung Cancers in Older vs Younger Participants

Phase II Trial Shows Overall Survival Benefit With VT-122 Plus Sorafenib in Advanced Hepatocellular Carcinoma

Less Frequent Use of Sentinel Lymph Node Biopsy and Higher Risk of Lymphedema in Black Women With Breast Cancer in Medicare Population

No Significant Difference in Time to Treatment Failure With Rituximab Retreatment vs Maintenance in Low-Tumor-Burden Follicular Lymphoma

Breast-Conserving Therapy Shows Survival Benefit Over Mastectomy in Patients With Early-Stage Hormone Receptor–Positive Disease

Study Finds No Link Between Wearing a Bra and Breast Cancer

Once-Weekly Breast Irradiation Following Lumpectomy Results in Better Compliance, Lower Costs, and Comparable Cosmetic Outcomes vs Daily Treatment

Disparities Persist in Early-Stage Breast Cancer Treatment

Novel Immunotherapy Vaccine Decreases Recurrence in HER2-Positive Breast Cancer Patients

FDA Approves Pembrolizumab for Advanced Melanoma

Study Finds Significant Increase in Bilateral Mastectomies Despite Lack of Survival Benefit

ASCO Issues New Guideline on Chemotherapy and Targeted Therapy in Advanced HER2-Negative or Unknown HER2 Status Breast Cancer

Survey Reveals Factors Influencing Women’s Consideration of Contralateral Prophylactic Mastectomy

Breast Cancer Surgery and Reconstruction Complications Are Rare, but Risk of Some Complications Higher With Bilateral vs Unilateral Mastectomy

Family Physician–Signed Reminder Letters Improve Return Rates for Women Overdue for Screening Mammography

FDA Grants Priority Review to Lanreotide Injection for Gastroenteropancreatic Neuroendocrine Tumors

Response to Neoadjuvant Chemotherapy and Tumor Subtype Are Strong Predictors of Locoregional Breast Cancer Recurrence

Angelina Jolie’s Story May Have Helped Double BRCA Testing Rates at a Canadian Cancer Center

Patients With Peritoneal Hepatocellular Carcinoma May Benefit From Cytoreductive Surgery With or Without Intraperitoneal Chemotherapy

No Benefit of Adding Cilengitide in Glioblastoma With Methylated MGMT Promoter

Circulating Tumor Cell Clusters More Likely to Cause Metastasis Than Single Cells

Addition of Irinotecan to Standard Chemotherapy Improves Survival in a Subset of Stage III Colon Cancer Patients

Melanoma With High Mitotic Rate Is Associated With Aggressive Histologic Features and Atypical Presentation

Adding Lenalidomide to R-CHOP Appears to Overcome Negative Prognostic Impact of the Non-Germinal Center B-Cell Phenotype in DLBCL

Danish Study Finds an Increased Risk of Developing Breast Cancer in Women With Previous False-Positive Mammography

Small but Statistically Significant Improvement in Overall Survival With Second-Line Addition of Ramucirumab to Docetaxel in Stage IV NSCLC

RNA Sequencing Could Help Doctors Tailor Unique Prostate Cancer Treatment Programs

Study Provides Blueprint for Next Generation of Chronic Myeloid Leukemia Treatment

Differences in Radiotherapy Coverage in the ACOSOG Z0011/Alliance Trial in Breast Cancer

Vitamin D Deficiency Worsens Response to Rituximab in Older Patients With Diffuse Large B-Cell Lymphoma

Better Survival, but Narrowing Gap, With Surgical vs Nonsurgical Treatment of Advanced Laryngeal Cancer

Study Shows Curcumin Blocks the Metastasis of Colon Cancer by a Novel Mechanism

Study Finds Widespread Adoption of Robot-Assisted Prostatectomy in United States

Inclusion of Endogenous Hormone Levels Improves Risk Prediction for Postmenopausal Breast Cancer

Promising Activity of Ibrutinib Plus Rituximab in High-Risk CLL

Brentuximab Vedotin Shows First-Line Activity in Phase I Study in CD30-Positive Peripheral T-Cell Lymphoma

High Concordance Between EGFR Mutations From Circulating-Free Tumor DNA and Tumor Tissue in NSCLC

Early Study Identifies Tumor-Suppressor Gene, Potential Therapy for Medulloblastoma

No Mortality Differences With Intermediate- or Short-Term Androgen Suppression With or Without Zoledronic Acid in Locally Advanced Prostate Cancer

Active Surveillance for Clinical Stage I Testicular Cancer Associated With ‘Excellent’ Outcomes

Accuracy of Edinburgh Ovarian Tissue Cryopreservation Criteria in Girls and Young Women With Cancer

Study Estimates Risk of Premature Menopause After Treatment for Hodgkin Lymphoma

Brachytherapy With Ruthenium-106 Found to Be Safe and Effective in Patients With Uveal Melanoma

Increasing Incidence of Merkel Cell Carcinoma in Queensland, Australia

Single-Institution Study Shows No Correlation of Primary Melanoma Regression With Sentinel Node Status

Neoadjuvant Chemotherapy Reduces Postoperative Morbidity in Women With Breast Cancer Undergoing Mastectomy

Genomic Sequencing Reveals Unique Genetic Alterations in Chromophobe Renal Cell Carcinoma

Swedish Study Reports Increasing Rates of Severe Infection Requiring Hospitalization After Prostate Biopsy

Bortezomib/Lenalidomide Combination Therapy Evaluated in Relapsed/Refractory Mantle Cell Lymphoma

Low Incidence of Colorectal Cancer, Elevated Rate of Postprocedure Hospitalization in Elderly Patients Undergoing Surveillance Colonoscopy

Poorer Psychosexual Functioning in Adult Female Survivors of Childhood Cancer

Jesse L. Steinfeld, MD, Past Surgeon General, ASCO President, and Valiant Foe of Big Tobacco, Dies at 87

Survival of Patients With a Common Lymphoma Is Worse Among Those With Low Income

More Than 50% of Older, Sick Adults Receive Cancer Screenings Unlikely to Provide Benefit

Updated Recommendations for Evaluation, Staging, and Response Assessment for Hodgkin and Non-Hodgkin Lymphoma: The Lugano Classification

ICML Imaging Working Group Issues Updated Guidelines on PET-CT for Staging and Response Assessment for FDG-Avid Lymphomas

Analysis of Randomized Bisphosphonate Osteoporosis Trials Indicates No Reduction in Risk of Postmenopausal Breast Cancer

Body Mass Index Positively Associated With Many Cancers in UK Study

Oncologists Respond Rapidly to Clinical Trial Evidence on Use of EGFR Inhibitors

More Accurate Identification of Molecular Subgroups May Better Guide Neoadjuvant Treatment of Breast Cancer

Proposed Modification Incorporating Depth of Invasion in Primary Staging for Oral Cancer

NeoALTTO Trial Shows No Benefit of Lapatinib Plus Trastuzumab in Secondary Survival Endpoints in HER2-Positive Early Breast Cancer

Previous Pulmonary Disease May Be Linked to Increased Lung Cancer Risk in Large Study

ALK-Positivity Prevalence on Immunohistochemistry and FISH in Resected Stage I to III Lung Adenocarcinoma

Study Detects New ALK Mutations at Neuroblastoma Relapse

NORCCAP Trial Shows Reduced Colorectal Cancer Incidence and Mortality With Flexible Sigmoidoscopy Screening at 11-Year Follow-up

FDA Approves Bevacizumab for Aggressive and Late-Stage Cervical Cancer

Researchers Identify Priority Targets for Immunotherapy in Epithelial Ovarian Cancer

ERSPC 13-Year Follow-up: Reduction in Prostate Cancer Mortality With PSA Screening, but High Overdiagnosis Rates Remain a Concern, Say Authors

NSAID Use May Reduce Risk of Breast Cancer Recurrence in Overweight and Obese Women

Similar 30-Day Outcomes With Laparoscopic vs Open Partial Hepatectomy in Single-Center Experience

Multiple Endocrine Neoplasia Type 1 Increases Risk of Breast Cancer

Scientists Pinpoint Gene Likely to Promote Childhood Cancers

Prostate Cancer Prevention Trial Identifies Men Most Likely to Undergo Challenging Study Procedures

Comprehensive Molecular Profiling of Lung Adenocarcinoma

No Difference in Response Rate but Overall Survival Benefit With First-Line FOLFIRI/Cetuximab vs FOLFIRI/Bevacizumab in Metastatic Colorectal Cancer

Successful Vemurafenib Treatment of Progressive BRAF V600E–Mutated Anaplastic Pleomorphic Xanthoastrocytoma

U.S. Lung Cancer Rates Vary by Subtype, Sex, Race/Ethnicity, and Age

Improvements in Overall Survival in Trilateral Retinoblastoma Due to Improved Chemotherapy and Earlier Detection

Negative PET/CT After One Cycle of Chemotherapy Strongly Predicts Favorable Outcome in Hodgkin Lymphoma

Enzalutamide Increases Time to First Skeletal-Related Event and Improves Quality-of-Life Outcomes in Castration-Resistant Prostate Cancer

FDA Approves First Noninvasive DNA Screening Test for Colorectal Cancer

TP53, TET2, and DNMT3A Mutations Predict Poorer Survival After Hematopoietic Stem Cell Transplant in Patients With Myelodysplastic Syndrome

FDA Approves Bortezomib Retreatment in Patients With Multiple Myeloma

Regular, Moderate Physical Activity Decreases Breast Cancer Risk in Postmenopausal Women

FDA Grants Orphan Drug Designation to Mocetinostat for Diffuse Large B-Cell Lymphoma

Phase II Study Supports Further Investigation of Neoadjuvant Carboplatin in Stage II to III Triple-Negative Breast Cancer

Study Quantifies Risk of Hereditary Breast Cancer in Carriers of PALB2 Mutations

Genome-Wide Association Study Finds New Genetic Risk Markers in Pancreatic Cancer

Study Identifies New Gene Fusion in Aggressive Estrogen Receptor–Positive Breast Cancer

Medicaid or No Insurance Associated With Worse Cancer-Specific Survival in Nonelderly Patients

Adding Gemtuzumab Ozogamicin to Chemotherapy Improves Event-Free Survival but Not Overall Survival in Children and Adolescents With De Novo AML

Large Differences in Survival According to Hospital Risk-Adjusted Margin Positivity Rate Status in Rectal Cancer Surgery

FDA Grants Fast Track Designation to Novel JAK2 Inhibitor for the Treatment of Myelofibrosis

Largest Cancer Genetic Analysis Reveals New Way of Classifying Cancer

Gut Microbiome Analysis May Provide an Effective Screening Tool for Colorectal Cancer

Statin Use After Colorectal Cancer Diagnosis Reduces Colorectal Cancer–Specific and All-Cause Mortality

College of American Pathologists Publishes Recommendations for Prostate Cancer Active Surveillance

Past Exposure to Thiopurines Associated With Increased Risk of Myeloid Disorders in Patients With Inflammatory Bowel Disease

Study Finds Nearly 10% of Cancer Survivors Continue to Smoke Years After Diagnosis

Increases Seen in Use of Digital Mammography and Related Screening Costs in Medicare Population, but No Increase in Early Detection

No Difference in Complication Rates or Hospital Stay With Robot-Assisted vs Open-Surgery Cystectomy in Bladder Cancer

Improved Prognosis Seen in Older Women With Mammography-Detected Breast Cancer

Renowned Pathologist Emmanuel Farber, MD, PhD, Dies

Significant Variation in Use of Single-Fraction Radiation Therapy for Palliation of Bone Metastases

Patient Navigation Significantly Improves Receipt of Antiestrogen Therapy but Not Radiation Therapy After Lumpectomy in Breast Cancer Patients

Taiwanese Study Shows Increased Risk of Head and Neck Cancer in Patients With Diabetes

Ruxolitinib Granted Priority Review for Polycythemia Vera

Blood and Saliva Tests Help Predict Recurrence of HPV-Related Oral Cancer

Investigational Compound ABT-414 Receives Orphan Drug Designation for Glioblastoma Multiforme

High Prevalence of and Shorter Survival With MYD88 Mutation in Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg-Type

Higher Stromal Tumor-Infiltrating Lymphocyte Level Associated With Improved Outcome in Triple-Negative Breast Cancer

Tumor Downstaging After Neoadjuvant Chemotherapy Strongly Predicts Improved Outcome After Surgery in Esophageal and Esophagogastric Junction Cancer

Study Suggests Recent Use of Some Birth Control Pills May Be Associated With Increased Breast Cancer Risk

PIK3CA Mutation Does Not Predict Outcome in Patients With Luminal Breast Cancer Receiving Endocrine Therapy

HLA Matching Finds Suitable Donors for Majority of Hematopoietic Stem Cell Transplant Candidates

Musculoskeletal Pain May Be Sign of Potential Tyrosine Kinase Inhibitor Withdrawal Syndrome in CML

Phase II Trial Shows Activity of Pemetrexed Plus Cisplatin in Treatment of Advanced, Persistent, or Recurrent Cervical Carcinoma

Growth-Driving Cancer Cells May Be Better Targets for Therapy Than Cells That Proliferate the Fastest, Study Suggests

Results of Genomic Analysis Suggest Strategy for Overcoming Ibrutinib Resistance in Mantle Cell Lymphoma

Minimal Residual Disease–Based Risk-Directed Therapy Is Effective in Children With BCR-ABL1–Like B-Cell ALL

Adults With Exclusively Pulmonary Metastases From Ewing Sarcoma May Benefit From Whole-Lung Irradiation

Anti–IL-6 Antibody Siltuximab Produces Durable Responses in Multicentric Castleman's Disease

Researchers Identify Genetic Mutations Linked to Salivary Gland Tumors

Acupuncture Provides Significant Quality-of-Life Improvements Among Breast Cancer Patients With Aromatase Inhibitor–Related Joint Pain

African Americans More Likely Than Whites to Receive Analgesic With Toxic Metabolite for Cancer Pain

Improved Overall Survival With Primary Over Consolidation Intraperitoneal Chemotherapy After Optimal Cytoreduction for Advanced Ovarian Cancer

Phase Ib Study Shows Activity of Ibrutinib Plus R-CHOP in First-Line Treatment of CD20-Positive B-Cell Non-Hodgkin Lymphoma

Study Helps Compare Risks of Endoscopic vs Surgical Resection for Early Esophageal Cancer

Researchers Identify Irreversible Inhibitor for KRAS Gene Mutation

Combination Afatinib and Cetuximab Yields Benefit in Lung Cancer Patients Resistant to EGFR Inhibitors

Promising Phase Ib Findings With Combined BRAF and MEK Inhibition With Vemurafenib and Cobimetinib in Advanced BRAF V600–Mutant Melanoma

Study Identifies Prevalence of Uterine Malignancy and Endometrial Hyperplasia at Time of Morcellation for Hysterectomy

Failure to Adopt a Healthy Lifestyle More Than Doubles Risk of Metabolic Syndrome in Childhood Cancer Survivors

First Surveillance Imaging at 6 Months May Be Adequate for Most Patients After Treatment for Early-Stage Non‒Small Cell Lung Cancer

FDA Expands Approved Use of Ibrutinib for Chronic Lymphocytic Leukemia

Phase II Trial Supports Use of First-Line Sunitinib vs Everolimus in Sequential Therapy in Metastatic Renal Cell Carcinoma

Adding Induction Chemotherapy to Chemoradiotherapy Does Not Improve Survival in Patients With N2 or N3 Locally Advanced Head and Neck Cancer

Statin Use Associated With Decreased Risk of Barrett's Esophagus

New Molecular Test Increases Odds of Correct Surgery for Thyroid Cancer Patients

Adaptive Intensity-Modulated Radiation Therapy Strategy May Ensure Adequate Target Coverage in Patients With Cervical Cancer

Dutch Phase II Study Supports Phase III Evaluation of Bevacizumab Plus Lomustine, but Not Bevacizumab Alone, in Recurrent Glioblastoma

Higher Plasma Vitamin D Concentration Associated With Reduced Cancer-Specific and All-Cause Mortality After Diagnosis of Colorectal Cancer

Antipain Agent Shrinks Oral Cancers, Sparing Healthy Tissue

Combined BRAF V600E and TERT Promoter Mutations Identify Aggressive and Recurrent Papillary Thyroid Cancer

Study Defines Four Molecular Subtypes of Gastric Cancer

FDA Approves Idelalisib for Three Types of Blood Cancers

Study Suggests That Primary Androgen-Deprivation Therapy Does Not Improve Long-Term Survival in Older Patients With Localized Prostate Cancer

Metabolic Enzyme Stops Growth of Most Common Type of Kidney Cancer

Corticosteroids Improve Fatigue, Appetite Loss, and Patient Satisfaction but Not Pain in Opioid-Treated Advanced Cancer Patients, Small Study Shows

Depression Associated With Less Definitive Therapy and Poorer Survival in Men With Clinically Localized Prostate Cancer

Anti–PD-1 Antibody Pembrolizumab Shows Activity and Good Tolerability in Ipilimumab-Refractory Advanced Melanoma

FDA Grants Bevacizumab Priority Review for Recurrent Platinum-Resistant Ovarian Cancer

No Disease-Free Survival Benefit of Adjuvant Zoledronic Acid in High-Risk Patients With Early Breast Cancer

Noninvasive Image Texture Analysis May Provide Tumor Heterogeneity Information With Prognostic Potential in NSCLC

Negative HPV Screening Test Result Is a Better Predictor of Cervical Cancer Risk Than a Negative Pap Test Result

Integrated Safety Analysis Shows Favorable Safety Profile of Single-Agent Trastuzumab Emtansine in HER2-Positive Metastatic Breast Cancer

Higher Marrow Levels of Plasmacytoid Dendritic Cells and Naive T Cells in Unrelated Donors Associated With Increased Survival in Stem Cell Transplant

Improved Survival in Hematologic Malignancies in Europe Between 1997 and 2008

Two Common Gene Variants Associated With Longer Telomere Length May Increase the Risk of Glioma

Minority of Older Patients With Low-Risk Prostate Cancer Managed by Observation

No Clinical Outcome Benefit With Aerobic Training Program in Cancer Patients With Heart Failure

Lenalidomide, Bortezomib, and Dexamethasone Induction and Consolidation Effective in Multiple Myeloma in French Phase II Trial

Robot-Assisted Surgery for Localized Prostate Cancer Controls Disease for 10 Years

Lanreotide Significantly Prolongs Progression-Free Survival in Metastatic Gastroenteropancreatic Neuroendocrine Tumors

Lymphovascular Invasion and Regression Identified as Independent Prognostic Factors in Thin Melanoma

Meta-Analysis Indicates Better Outcomes With Charged-Particle Therapy vs Photon Therapy in Nasal Cavity and Paranasal Sinus Malignancies

Poorer Progression-Free Survival and Overall Survival Seen in Youngest and Oldest Patients With Metastatic Colorectal Cancer

New Combination Drug Controls Tumor Growth and Metastasis in Mice

Effects of Aspirin, Hormone Replacement Therapy, Smoking, and BMI on Age- and Cancer-Associated DNA Methylation in the Colon in Women

Study Identifies Clinicopathologic and Adjuvant Treatment Characteristics Linked to Very Low Risk of Local Recurrence After Breast-Conserving Surgery

Cutaneous Embolization of Doxorubicin Drug-Eluting Beads in Patient With Liver Metastases From Breast Cancer

Adjuvant Chemoradiation With Docetaxel Plus Cetuximab Shows Promise in High-Risk Squamous Cell Carcinoma of the Head and Neck

FDA Grants Bevacizumab Priority Review for Certain Types of Cervical Cancer

New Androgen Receptor Inhibitor Shows Activity in Metastatic Castration-Resistant Prostate Cancer

Gene Signature May Predict Which Breast Cancer Patients Will Benefit From Tamoxifen

Study Compares Tamoxifen Gel Applied to the Breast With Oral Tamoxifen in Women With DCIS

Vasectomy Associated With Modestly Increased Risk of High-Grade and Lethal Prostate Cancer

Blocking Tumor-Derived Protein Halts Cachexia in Preclinical Study

Testicular Cancer Rates Are on the Rise in Young Hispanic Americans

Multidimensional Analysis Provides More Accurate Prognostic Biomarkers in Colorectal Cancer

Adding Ziv-Aflibercept to Topotecan Improves Progression-Free Survival but Increases Toxicity in Platinum-Treated Small Cell Lung Cancer

Total-Body Photography and Sequential Digital Dermoscopy Assist in Early Diagnosis of Primary Melanoma in High-Risk Individuals

Variations in Key Gene Predict Prostate Cancer Patients’ Risk for Radiation-Induced Toxicity

Study Identifies Novel Genomic Changes in Lung Adenocarcinoma

Study Identifies Irinotecan Dosing Levels Based on UGT1A1 Genotype

Long-Term Central Venous Catheter Use Associated With Three- to Sixfold Increased Risk of Infection in Older Patients With Cancer

High-Dose Melphalan Plus Autologous Stem Cell Transplantation as Consolidation Shows Benefit in Relapsed Multiple Myeloma After Previous Transplant

Brain Tumor Invasion Along Blood Vessels May Lead to New Cancer Treatments, Preclinical Study Suggests

Fox Chase Cancer Center Researchers Recommend Updating the Staging Criteria for Breast Cancers With Skin Involvement

Cyclophosphamide Noninferior to Ifosfamide as Part of Consolidation Treatment in Standard-Risk Ewing Sarcoma

Patient Navigation Improves Time to Diagnosis Resolution and Treatment Initiation

French Phase III Trial Shows No Benefit of Neoadjuvant Chemoradiation in Stage I and II Esophageal Cancer

Study Identifies Patient and Tumor Characteristics Associated With BRAF and KRAS Mutations in Colon Cancer

Preclinical Study Reveals Heparan Sulfate Suppresses Growth of Neuroblastoma

Frailty Predicts Noninitiation but Not Discontinuation of Adjuvant Hormonal Therapy in Older Women With Breast Cancer

No Survival Benefit With Everolimus After Failure of Sorafenib in Advanced Hepatocellular Carcinoma

Adjuvant Paclitaxel Not Equivalent to Doxorubicin/Cyclophosphamide in Breast Cancer With 0 to 3 Positive Axillary Nodes

Researchers Identify Events Causing Bone Marrow Inflammation Leading to Blood Disorders

FDA Grants Breakthrough Therapy Designation to Investigational Chimeric Antigen Receptor Therapy for Relapsed/Refractory ALL

ABCA Transporter Gene Expression Is Associated With Poor Outcome in Epithelial Ovarian Cancer

FDA Grants Orphan Drug Designation to ENMD-2076 for Hepatocellular Carcinoma

Adding Oxaliplatin to Leucovorin/Fluorouracil Increases Survival in Second-Line Treatment of Gemcitabine-Refractory Pancreatic Cancer

No Survival Benefit of Video-Assisted Thoracoscopic Partial Pleurectomy vs Talc Pleurodesis in Malignant Pleural Mesothelioma

No Increased Risk for Cancer in Patients Receiving Tumor Necrosis Factor–Alpha Antagonists for Inflammatory Bowel Disease

FDA Approves Belinostat for Relapsed or Refractory Peripheral T-Cell Lymphoma

Propensity-Matched Analysis Shows Similar Outcomes for Segmentectomy vs Lobectomy in Stage I NSCLC

Study Identifies Modifiers of Breast and Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

No Improvement in Local Recurrence With Brachytherapy After Sublobar Resection in Patients With High-Risk Stage I NSCLC

Scientists Engineer Nanoparticles to Prevent Bone Cancer, Strengthen Bones

Abbreviated Screening MRI Protocol Is Highly Accurate in Breast Cancer Detection in Women at Increased Risk

Study Shows Annual MRI Plus Mammography May Be Effective Screening Program for Women at High Risk for Breast Cancer

Multifaceted Intervention Improves Adherence to Annual Colorectal Cancer Screening in Primarily Latino Community Health Centers

5-Year Results of the European EXPERT-C Trial Show Benefit of Cetuximab in TP53 Wild-Type Rectal Cancer Subgroup

HIV-Infected People With Early-Stage Cancers Are Up to Four Times More Likely to Go Untreated for Cancer

New Screening Approach Identifies Cancer Mutations in Melanoma That May Lead to More Effective Immunotherapies

Adding Rilotumumab to First-Line Chemotherapy May Benefit Patients With Advanced Gastric or Esophagogastric Junction Adenocarcinoma

American College of Physicians Issues Guideline Recommending Against Routine Pelvic Exams for Asymptomatic Women

FDA Grants Breakthrough Therapy Designation to Blinatumomab for Acute Lymphoblastic Leukemia

Postdiagnosis Calcium and Milk Intake May Be Associated With Improved Overall Survival in Colorectal Cancer Patients

Excess Risk of Chronic Late Effects of Treatment in Children With Standard-Risk ALL

Surgical Treatment for Metastatic Melanoma of the Liver Increases Overall Survival in Select Group of Patients

Phase III Trial Shows Improved Survival With TAS-102 in Metastatic Colorectal Cancer Refractory to Standard Therapies

Telephone-Based Intervention Produces Weight Loss in Postmenopausal Women With Breast Cancer Receiving Letrozole

Phase II Trial Shows Improved Progression-Free Survival but Greater Toxicity With Selumetinib vs Chemotherapy in Metastatic Uveal Melanoma

Study of Over 450,000 Women Finds 3D Mammography Detects More Invasive Cancers and Reduces Recall Rates

Immediate Breast Reconstruction After Mastectomy More Likely Among Canadian Women With Higher Income Who Are Treated at Teaching Hospitals

No Benefit of Adding Telomerase Peptide Vaccine to Chemotherapy in Patients With Advanced Pancreatic Cancer

Uninsured Young Adults Have Poorer Cancer-Specific Outcomes

HPV-Positive Disease Predicts Longer Overall Survival After Progression of Oropharyngeal Squamous Cell Carcinoma

Adding Novel Agent to Standard Therapy Improves Survival in Patients With Pancreatic Cancer After Prior Gemcitabine-Based Therapy

Daily Low-Dose Aspirin Use May Reduce Risk of Developing Pancreatic Cancer

FDA Advisory Committee Votes Against Accelerated Approval for Olaparib in Ovarian Cancer

No Disease-Free Survival Benefit of Adding Cetuximab to FOLFOX4 in KRAS Exon 2 Wild-Type Resected Stage III Colon Cancer

St. Jude Children’s Research Hospital Appoints James R. Downing, MD, as CEO

High Neutrophil-to-Lymphocyte Ratio Is Associated With Poorer Survival in Solid Tumors Overall and in Individual Cancer Types

Synthetic Triterpenoids Show Promise in Preventing Colitis-Associated Colon Cancer in Preclinical Study

Combining Multiple Imaging Approaches Can Better Distinguish Malignant and Benign Breast Tumors and Reduce Unnecessary Biopsies

Event-Free Survival Benefit, Greater Toxicity of Augmented Postremission Therapy for Children/Young Adults With High-Risk Acute Lymphoblastic Leukemia

Phase III Trial Indicates That S-1 Monotherapy Should Remain Standard Treatment of Locally Advanced Gastric Cancer in Japan

No Overall Survival Improvement but Some Palliative Benefit With Gefitinib vs Placebo in Esophageal Cancer Progressing After Chemotherapy

BPA Stimulates Growth of Breast Cancer Cells, Diminishes Effect of Treatment

Oncologist Communication Skills Training Program Effective for Both Oncologists and Patients

Tumor Microenvironment of Metastasis Score Independently Predicts Distant Metastasis in Estrogen Receptor–Positive/HER2-Negative Breast Cancer

Adding Antiangiopoietin Agent Trebananib to Paclitaxel Improves Progression-Free Survival in Recurrent Epithelial Ovarian Cancer

Early Evidence Suggests Proton Therapy May Offer Safe, Long-Term Treatment for Hodgkin Lymphoma

New Tool Predicts Financial Pain for Cancer Patients

No Improvement in Long-Term Outcomes With Extended Colectomy for Sporadic Colorectal Cancer in Patients Younger Than Age 50

HERA Trial 8-Year Follow-up Shows Low Rate of Trastuzumab-Associated Cardiac Dysfunction

EPIC Cohort Study: High Thyroglobulin and Low TSH Precede Differentiated Thyroid Cancer, but Neither Can Be Used in Screening

Development of Orteronel for Prostate Cancer Voluntarily Discontinued by Takeda

Racial Disparities in Sentinel Lymph Node Biopsy in Women With Breast Cancer

Diversity of Intestinal Tract Bacteria Associated With Mortality Outcomes After Stem Cell Transplant, Study Shows

Surgical Treatment Delay May Not Result in Worse Outcomes in Patients With Colon Cancer

Similar Survival Rates, Less Toxicity Reported With Reduced-Intensity vs Myeloablative Total-Body Irradiation Before Transplant in Acute Leukemia

Priming Pancreatic Cancer Cells With a Vaccine May Allow Them to Respond to Immunotherapy

‪Survey Finds Booming E-Cigarette Online Market

Glioma-Associated Antigen Peptide Vaccination Produces Antigen-Specific T-Cell Response and Clinical Activity in Children With High-Grade Gliomas

Combined Index Predicts Early Multiple Myeloma Progression-Related Death in Patients Receiving Front-Line Autologous Stem Cell Transplantation

Study Reveals Long-Term Benefits With Prone Hypofractionated Radiation Therapy and a Concurrent Boost in Early-Stage Breast Cancer

Study Identifies Two Proteins as Markers of Response to Neoadjuvant Chemotherapy for Ovarian Cancer

Lung-MAP Launches: First Precision Medicine Trial From National Clinical Trials Network

Study Finds Changes in Brain Activity in Breast Cancer Patients Receiving Chemotherapy

Stage Migration and Dilution of Higher Stages With PET in Head and Neck Cancer in a Managed Care Setting

Study Finds Anorectal Melanoma Is Diagnosed at Later Stages and Is Often Misdiagnosed

Brain Tumor Risk Greater in Women Who Begin Menstruation at Older Age, Study Reports

Higher Distant Invasive Breast Cancer Recurrence Risk for HER2-Positive T1b vs T1a Node-Negative Localized Breast Cancer

FDA Approves Radioactive Diagnostic Imaging Agent to Help Determine the Extent of Head and Neck Cancer in the Body

Danish Study Shows Increased Risk of Cardiovascular Disease Throughout Life in Survivors of Adolescent and Young Adult Cancer

Needle Biopsy Underused in the United States, Adversely Affecting Breast Cancer Treatment

Survivors of Childhood Cancers Experience Frequent Hospitalizations Years After Cancer Treatment

Phase III Trial of Adding Figitumumab to Chemotherapy in Advanced Nonadenocarcinoma NSCLC Stopped Early for Futility and Increased Harm

Palliative Resection of Primary Tumor May Improve Survival in Patients With Metastatic Colorectal Cancer

NLST Analysis: Lung Screening–Detected Abnormalities Other Than Cancer Result in Smoking Cessation

FDA Approves Magnetic Resonance Contrast Agent for Evaluation of Breast Cancer

Barbara L. McAneny, MD, To Serve as Chair of the AMA Board of Trustees

Mammography Has Led to Fewer Late-Stage Breast Cancers, Study Finds

Adding Lapatinib to Paclitaxel Does Not Improve Survival as Second-Line Therapy in Asian Patients With HER2-Positive Advanced Gastric Cancer

Modeling Shows Digital vs Film Mammography Screening for Breast Cancer Produces Small Benefit at Increased Cost

ASCO 2014: Stopping Statins Is Safe and Can Improve Quality of Life for Patients With Cancer Near the End of Life

ASCO 2014: Goserelin Helps Preserve Fertility Among Women Receiving Chemotherapy for Hormone Receptor–Negative Breast Cancer

ASCO 2014: Starting Palliative Care Support for Family Caregivers at the Time of Cancer Diagnosis Improves Quality of Life

Study Identifies Genetic Variant Associated With Increased Risk of Invasive Lobular Breast Cancer

Initial Treatment of Ductal Carcinoma in Situ May Affect Subsequent Treatment of Tumor Recurrences After Surgery

ASCO 2014: Women With Breast Cancer and Bone Metastasis Can Safely Scale Back Frequency of Zoledronic Acid Dosing

ASCO 2014: Lower-Dose Radiation May Reduce Long-Term Side Effects Without Compromising Survival in Certain HPV-Positive Head and Neck Cancers

MEK Inhibitor Use Associated With Bilateral Subfoveal Neurosensory Retinal Detachment

ASCO 2014: Enzalutamide Before Chemotherapy Prolongs Progression-Free and Overall Survival in Metastatic Prostate Cancer

Greater Progression-Free Survival Benefit of Maintenance Olaparib in BRCA-Mutant Platinum-Sensitive Recurrent Serous Ovarian Cancer

First-Line Lenalidomide Plus Rituximab Is Safe and Effective in Older and Younger CLL Patients, Phase II Study Shows

ASCO 2014: Ipilimumab/Nivolumab Combination Achieves Long-Term Survival for Patients With Advanced Melanoma

ASCO 2014: PD-1–Targeting Antibody Pembrolizumab Produces Long-Term Responses in Patients With Metastatic Melanoma

ASCO 2014: Adjuvant Ipilimumab Significantly Improves Recurrence-Free Survival in Patients With High-Risk Stage III Melanoma

Early Change in Chemotherapy Based on Elevated Circulating Tumor Cells Does Not Improve Outcome in Metastatic Breast Cancer

Smokers With BRCA2 Mutation Have Increased Risk of Developing Lung Cancer

Adjuvant! Online Performs Poorly in Older Patients With Breast Cancer in Dutch Study

Ibrutinib Resistance Mutations Identified in CLL Patients

ASCO 2014: Cediranib Plus Olaparib Significantly Increases Progression-Free Survival in Women With Recurrent Ovarian Cancer

ASCO 2014: Lenvatinib Yields High Response Rates, Delays Progression in Patients With Radioiodine-Resistant Differentiated Thyroid Cancer

ASCO 2014: Adding Lapatinib to Adjuvant Trastuzumab Does Not Improve Outcomes in Early-Stage HER2-Positive Breast Cancer

ASCO 2014: Chemotherapy Plus Either Bevacizumab or Cetuximab Results in Similar Survival Benefits in Metastatic Colorectal Cancer

ASCO 2014: Ceritinib Shows Rapid, Durable Response in ALK-Positive NSCLC

ASCO 2014: Adding Docetaxel to Androgen-Deprivation Therapy Significantly Improves Survival in Hormone-Sensitive Prostate Cancer

ASCO 2014: Adjuvant Exemestane With Ovarian Function Suppression Better at Preventing Breast Cancer Recurrence Than Tamoxifen

ASCO 2014: Ibrutinib Significantly Delays Disease Progression and Extends Survival in Relapsed CLL

ASCO 2014: Addition of Chemotherapy to Radiotherapy Improves Survival in Low-Grade Glioma

ASCO 2014: Second-Line Treatment With Ramucirumab Plus Standard Docetaxel Extends Overall Survival in Advanced Lung Cancer

ASCO 2014: Investigational Anti–PD-L1 Antibody Demonstrates Promising Activity in Certain Patients With Metastatic Bladder Cancer

ASCO 2014: Bortezomib Combination Significantly Improves Progression-Free Survival in Newly Diagnosed Mantle Cell Lymphoma

ASCO 2014: Patients With Metastatic Colon Cancer Respond to New Combination Therapy, Phase IB Study Shows

ASCO 2014: Women With BRCA Mutations Report Significant Side Effects Following Risk-Reducing Salpingo-Oophorectomy

ASCO 2014: Men Who Receive Radiation Therapy for Prostate Cancer Have Increased Long-Term Risk of Bladder or Rectal Cancer

Study Identifies Risk of Chemotherapy-Related Hospitalization for Early-Stage Breast Cancer Patients

Five or More Blistering Sunburns in Early Life May Raise Melanoma Risk by 80%

Greater Risk of Pretreatment Cognitive Impairment in Older Breast Cancer Patients With More Advanced Disease and Greater Comorbidity

Central Pancreatectomy for Low-Grade Neoplasms Results in 'Excellent' Pancreatic Function but Substantial Morbidity

No Differences in Surgical Outcomes With Four Different Chemotherapy Regimens Plus Preoperative Radiotherapy in Rectal Cancer

ASCO Guideline Update Recommends Tamoxifen for Up to 10 Years for Women With Nonmetastatic Hormone Receptor–Positive Breast Cancer

Korean Trial Shows Similar Disease-Free Survival With Laparoscopic vs Open Surgery in Mid- or Low-Rectal Cancer After Neoadjuvant Chemoradiotherapy

Analysis Shows Advertising by Cancer Centers Frequently Evokes Hope and Fear, but Provides Little Information

FDA Approves Palonosetron Hydrochloride to Prevent Chemotherapy-Induced Nausea and Vomiting in Pediatric Patients

Physicians and Patients/Caregivers Frequently Disagree on Medicare Resource Allocations for Patients With Advanced Head and Neck Cancer

No Apparent Benefit of Adding Cetuximab to Gemcitabine Plus Oxaliplatin in Advanced Biliary Tract Cancer

Gene Mutation Found for Aggressive Form of Pancreatic Cancer

FDA Approves Panitumumab Plus FOLFOX for Wild-Type KRAS Metastatic Colorectal Cancer

No Apparent Benefit of Rituximab After Lymphoma-Directed Conditioning and Allogeneic Stem Cell Transplantation for Relapsed/Refractory Aggressive NHL

Proactive Patient-Centered Program May Reduce the Risk of Lymphedema in Survivors of Breast Cancer

No Progression-Free or Overall Survival Benefit With Second- or Third-Line Erlotinib vs Docetaxel in EGFR-Unselected Japanese NSCLC Patients

Circulating Tumor Cells Predict Disease-Free Survival and Overall Survival in Patients With Early Average- to High-Risk Breast Cancer

More Toxicity Associated With Addition of Sorafenib to Yttrium-90 Radioembolization Prior to Liver Transplantation

Percentage Dense Area Stronger Than Absolute Dense Area as Mammography Risk Factor for Breast Cancer

No Overall Survival Improvement With Elacytarabine vs Investigator Choice in Patients With Relapsed/Refractory AML

Majority of Women Undergoing Contralateral Prophylactic Mastectomy Have No Major Risk Factors for Developing Cancer in Both Breasts

Lenalidomide Plus R-CHOP21 Highly Active in Elderly Patients With Untreated Diffuse Large B-Cell Lymphoma

Supportive Tumor Tissue Surrounding Cancer Cells Hinders Pancreatic Cancer Progression, Preclinical Study Reports

The Cancer Community Mourns the Passing of Selma Schimmel

Mutations Associated With Arsenic Resistance in Acute Promyelocytic Leukemia

Proteomic Signature for EGFR Inhibitor Therapy Predicts Survival Benefit of Second-Line Chemotherapy vs Erlotinib in NSCLC

Study Uses Comprehensive Genomic Tumor Testing to Match Lung Cancer Patients With Targeted Therapies

Study Reveals More Than One-Third of Patients With ‘Low-Risk’ Prostate Cancer on Conventional Biopsy Have More Aggressive Tumors on Targeted Biopsy

Insulin-Like Growth Factor-1 Score Improves Assessment of Prognosis in Hepatocellular Carcinoma

High Expression of Brachyury Associated With Poor Prognosis in Breast Cancer Patients Receiving Adjuvant Tamoxifen

No Overall Survival Improvement With Ipilimumab After Radiotherapy in Metastatic Castration-Resistant Prostate Cancer Progressing After Docetaxel

Study Suggests Less Frequent Cardiac Screening May Be Preferable for Survivors of Childhood Cancer

Low Use of Chemotherapy in Last 14 Days of Life at MD Anderson Cancer Canter

Radium-223 Dichloride Significantly Prolongs Time to First Symptomatic Skeletal Event in Patients With Castration-Resistant Prostate Cancer

Blocking CD47 Signals May Offer New Therapeutic Approach in the Treatment of Pancreatic Cancer

Early Study Shows Improved Survival With Radioimmunotherapy/Gemcitabine Combination in Patients With Advanced Pancreatic Ductal Cancer

Studies Evaluate Racial Variations, Cost, and Influence of Access to Care in the Management and Treatment of Testicular Cancer

Results of Three Studies Indicate 17-Gene Assay Is a Significant Predictor of Prostate Cancer Aggressiveness at the Time of Diagnosis

IASLC/American Thoracic Society/European Respiratory Society Classification of Lung Adenocarcinoma Has Predictive Value for Recurrence and Survival

Accelerated Methotrexate, Vinblastine, Doxorubicin, Cisplatin With Pegfilgrastim Is Effective, Well-Tolerated Neoadjuvant Therapy for Bladder Cancer

Neoadjuvant Dose-Dense Methotrexate, Vinblastine, Doxorubicin, Cisplatin With Pegfilgrastim: Safe and Effective in Muscle-Invasive Urothelial Cancer

U.S. Cervical Cancer Rates Higher Than Previously Reported, Particularly Among Older Women and African American Women

Analysis Finds Wide Variation in Lung Cancer Rates Globally

Carcinogens Found in Water Pipe Smoking May Increase Risk for Cancer

Necitumumab Plus Chemotherapy Shows Overall Survival Benefit in Patients With Squamous NSCLC

Frequent but Nontargeted Use of Pharmacologic Thromboprophylaxis in Hospitalized Patients With Cancer

Obesity Substantially Increases Breast Cancer Mortality Only in Women With Premenopausal Estrogen Receptor–Positive Disease

Study Projects Nationwide Low-Dose CT Screening Will Identify More—and Earlier-Stage—Lung Cancers, but Comes With Substantial Medicare Costs

Novel Targeted Drug May Provide a New Treatment Option for Patients With Recurrent Pigmented Villonodular Synovitis

New EGFR Inhibitor AZD9291 Shows Promising Activity in Treatment-Resistant Non–Small Cell Lung Cancer

Delaying Androgen Deprivation Therapy May Be Safe for Men With Prostate Cancer Relapse Detected by PSA Testing

Novel Target Found for Chemotherapy-Resistant Leukemia Cells

Diffuse Erythema Predicts Complete Remission of Skin Disease With Alemtuzumab in Leukemic Cutaneous T-Cell Lymphoma

Epigenetically Reprogrammed Cells Generate Functional Cord Blood Stem Cells for Transplantation

Phase II Feasibility Study Tests Four Molecular-Based Hypotheses in Advanced Colorectal Cancer

Squamous Cell Carcinoma Within Advanced Basal Cell Carcinoma During Vismodegib Treatment: Importance of Serial Biopsy

Phase I Study Finds Novel Antibody Shows Promise in Children With Advanced Neuroblastoma

Immunotherapy May Be Effective in the Treatment of Multiple Myeloma

PET Plus CT-Assessed Relative Tumor Size Reduction After Chemotherapy Identifies High Risk for Progression and Relapse in Advanced Hodgkin Lymphoma

Tools for Identifying Pathologically Insignificant Prostate Cancer Are Inaccurate In Unscreened Men

Cowden Syndrome With Germline PTEN Mutations Puts Patients at High Risk of Second Cancers

Preoperative Positron-Emission Tomography May Be Beneficial in Reducing the Number of Unnecessary Surgeries in Patients With Lung Cancer

NIH Study Demonstrates That a New Cancer Immunotherapy Method Could Be Effective Against Epithelial Cell Cancers

No Difference in Postsurgery Fatigue With Laparoscopic vs Open Surgery for Colorectal Cancer With Enhanced Recovery Program

Incidence of Breast Cancer According to Joint Hormone Receptor and HER2 Status Differs According to Race/Ethnicity and Other Factors

Tumor Factors Associated With Poorer Overall Survival in Patients With Intrahepatic Cholangiocarcinoma Undergoing Curative Intent Surgery

False-Positive Screening Mammograms Associated With Short-Term Anxiety but No Reduced Intention to Undergo Subsequent Mammography

Researchers Identify Enzymes Associated With Chemoresistance in Ovarian Cancer

Magnetic Resonance–Guided Focused Ultrasound Reduces Pain From Bone Metastases

Adding Neoadjuvant Carboplatin to Taxane, Anthracycline, and Targeted Therapy Increases Pathologic Complete Response in Triple-Negative Breast Cancer

Lower Densities of Gastroenterologists, General Surgeons, and Radiation Oncologists in Rural vs Urban U.S. Counties

Glutamine Ratio Is Key Indicator of Tumor Aggression in Ovarian Cancer, Study Finds

Statin Use Associated With Reduced Risk of Prostate Cancer Recurrence

Good Prognosis for High-Risk Ph-Negative ALL With Chemotherapy After Early Cytologic Response and Low Minimal Residual Disease Level on Flow Cytometry

High Preoperative Hepatitis B Surface Antigen Level Predicts Hepatocellular Carcinoma Recurrence in Patients With Low HBV DNA

Ado-Trastuzumab Emtansine Improves Progression-Free Survival vs Physician’s Choice in Previously Treated Advanced HER2-Positive Breast Cancer

Dual Method to Remove Precancerous Colon Polyps May Substantially Reduce Health-Care Costs

Study Confirms Clinical Benefit for Interleukin-2 Immunotherapy in Patients With Advanced Kidney Cancer

Minority of Oncologists and Primary Care Physicians Fully Discuss Survivorship Care Plans With Cancer Survivors

No Apparent Increase in Risk of Oral HPV Infection in Sexual Partners of HPV-Positive Patients With Oropharyngeal Cancer

ASCO Releases Clinical Practice Guideline on Systemic Therapy for Patients With Advanced HER2-Positive Breast Cancer

ASCO Releases Companion Guideline on Disease Management for Patients With Advanced HER2-Positive Breast Cancer and Brain Metastases

FDA Approves Omacetaxine Mepesuccinate for Injection for Home Administration

Modafinil Not Better Than Placebo for Fatigue in Lung Cancer Patients

Increased Incidence of Thyroid Cancer: An Epidemic of Diagnosis?

Final Overall Survival Results Show No Difference for Pazopanib vs Sunitinib in First-Line Treatment of Clear Cell Metastatic Renal Cell Carcinoma

Computational Model Can Predict Therapy Outcomes in Prostate Cancer With Bone Metastasis

Hyperfractionated Radiation Therapy Improves Local-Regional Control Without Increasing Late Toxicity in Locally Advanced Head and Neck Cancer

Surgery for Metastatic Breast Cancer Associated With High Complication Rate

Axillary Radiotherapy Associated With Fewer Side Effects Than Lymph Node Dissection in AMAROS Analysis

Cryoablation of Breast Tumors Successful in 69% of Patients With Early-Stage Disease in Phase II Trial

Severe Vitamin D Deficiency Is Associated With Aggressive Prostate Cancer, Study Finds

Breath Analysis Offers Noninvasive Method to Detect Early Lung Cancer

Black Patients With Salivary Gland Mucoepidermoid or Squamous Cell Carcinoma Have Poorer Disease-Specific Survival Than White Patients

Anti–Interleukin-1 Alpha Antibody MABp1 Is Well Tolerated, Safe, and Active in Phase I Trial in Refractory Cancers

Irradiated Stents Prolong Survival and Reduce Dysphagia Compared With Conventional Stents as Palliative Treatment in Unresectable Esophageal Cancer

FDA Approves Ceritinib for Late-Stage Lung Cancer

Poor Quality of Life Does Not Predict Low Survival Rates in High-Risk Lung Cancer Patients Undergoing Surgery

Differences in Lifestyle Habits and Poorer Adherence to Radiation Therapy in Patients With HPV-Negative vs HPV-Positive Oropharyngeal Carcinoma

Cumulative Risk of Breast Cancer Reaches 30% by Age 50 After Chest Irradiation for Childhood Cancer

No Difference in Disease-Free Survival but Less Steroid Dependence With Adrenal-Sparing Surgery vs Adrenalectomy in Pheochromocytoma

FDA Approves Mercaptopurine Oral Suspension for Acute Lymphoblastic Leukemia

Novel DNA Vaccine Generates Immunity Against Tumor Vasculature Protein in Preclinical Study

Receiving Chemotherapy After a Breast Cancer Diagnosis May Affect a Patient’s Long-Term Employment

Sorafenib Improves Progression-Free Survival in Progressive Radioactive Iodine–Refractory Differentiated Thyroid Cancer

Tumor Regression Grading After Preoperative Chemoradiotherapy for Rectal Carcinoma Predicts Distant Metastasis Risk and Disease-Free Survival

First-Generation EGFR Tyrosine Kinase Inhibitors Associated With Poorer Progression-Free Survival vs Conventional Chemotherapy in EGFR Wild-Type NSCLC

ASTRO Issues Guideline on the Role of Postoperative Radiation Therapy for Endometrial Cancer

FDA Approves First HPV Test for Primary Cervical Cancer Screening

Human Papillomavirus Vaccine Proves Effective in Women With HIV

FDA Proposes to Extend Its Tobacco Authority to Additional Tobacco Products, Including E-Cigarettes

Doxepin Rinse Reduces Radiotherapy-Associated Oral Mucositis Pain in Patients With Head and Neck Cancer

Ado-Trastuzumab Emtansine Plus Pertuzumab Shows Activity and No Unexpected Toxicity in HER2-Positive Locally Advanced or Metastatic Breast Cancer

FDA Approves Siltuximab for Rare Castleman’s Disease

Study Shows Decreasing Numbers of Colorectal Cancer Resections and Improved In-Hospital Mortality in Older Patients

FDA Grants Orphan Drug Designation to Alvocidib for the Treatment of Acute Myeloid Leukemia

Experimental Drug Receives Fast Track Designation as Second-Line Chemotherapy for Metastatic Castration-Resistant Prostate Cancer

Adding Everolimus to Trastuzumab/Vinorelbine Prolongs Progression-Free Survival but Increases Toxicity in Trastuzumab-Resistant Advanced Breast Cancer

Use of Intraoperative Frozen Section Margin Assessment May Decrease Reoperations in Breast Cancer Patients Undergoing Lumpectomy

Researchers Identify Pathway That Drives Development of Cancer 'Stemness' and Drug Resistance

Swedish Men Living Alone Have Later Stage at Diagnosis and Worse Survival in Cutaneous Malignant Melanoma

Addition of Tigecycline to Empiric Therapy Improves Success Rate in Febrile Neutropenic Patients With Hematologic Malignancy

Sildenafil Use May Be Associated With Increased Risk of Melanoma

FDA Approves Ramucirumab for Stomach Cancer

New Gene Variant Found That Increases the Risk of Colorectal Cancer From Eating Processed Meat

Researchers Uncover Link Between Down Syndrome and Leukemia

High Total/Saturated Fat Intake Associated With Increased Risk of Hormone Receptor–Positive Breast Cancer and HER2-Negative Breast Cancer

Interim Analysis of Phase III AVAST-M Trial Shows No Overall Survival Benefit of Adjuvant Bevacizumab vs Observation in High-Risk Melanoma

Gene Signatures Identified by Meta-Analysis Predict Survival and Suboptimal Debulking in Late-Stage Ovarian Cancer

Chronic Inflammation in Benign Prostate Tissue Is Associated With Aggressive Prostate Cancer

European Phase II Study Indicates Activity of Enzalutamide in Hormone-Naive Prostate Cancer

FDA Discourages Use of Laparoscopic Power Morcellation for Removal of Uterus or Uterine Fibroids

‘Too Much and Too Little Care’ in Pulmonary Nodule Evaluation

Colonoscopy Adenoma Detection Rate Is Inversely Proportional to Risk of Interval Colorectal Cancer and Colorectal Cancer Mortality

FDA Approves Ofatumumab for Previously Untreated Chronic Lymphocytic Leukemia

Total Parotidectomy May Benefit Patients With Cutaneous Squamous Cell Carcinoma or Malignant Melanoma With Metastasis to the Parotid Superficial Lobe

Panitumumab Not Inferior to Cetuximab in Overall Survival in Chemotherapy-Refractory Wild-Type KRAS Metastatic Colorectal Cancer

Volasertib Granted Orphan Drug Designation for Acute Myeloid Leukemia

Novel Prognostic Indices Validated for Cytogenetically Normal Acute Myeloid Leukemia

Novel Blood-Based Biomarkers May Predict Breast Cancer Recurrence and Treatment Response

Investigators Attempt to Increase Lapatinib Exposure Through Intermittent Dosing in HER2-Positive Breast Cancer

Unexpected Protein Partnership Has Implications for Cancer Treatment

Breast Cancer Risk Variant Associated With Increased Lung Cancer Risk in Women

Quality-of-Life Study in NCIC MAP.3 Trial Shows Limited Negative Impact of Daily Exemestane in Breast Cancer Prevention

Study Finds a Quarter of Men Drop Out of Prostate Cancer Monitoring, Casting Doubt on Safety of Active Surveillance

ASCO Releases Adapted Guideline on Screening, Assessment, and Management of Fatigue in Adult Survivors of Cancer

ASCO Issues Adapted Guideline on Screening, Assessment, and Care of Anxiety and Depressive Symptoms in Adults With Cancer

ASCO Releases Guideline on Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of Adult Cancers

Perioperative Chemotherapy for High-Risk Bladder Cancer Improves Survival but Is Not Routinely Administered

Gene Sequencing Project Discovers Mutations Tied to High-Grade Gliomas in Young Children

Study Examines Protein Expression Biomarkers in HPV-Negative Squamous Cell Carcinomas of the Head and Neck

Researchers Identify Transcription Factors Distinguishing Glioblastoma Stem Cells

IGH@ Translocations Are Prevalent in Teenagers and Young Adults With Acute Lymphoblastic Leukemia

Worse Progression-Free Survival With Addition of Cetuximab to Chemotherapy in Patients With Resectable Colorectal Liver Metastasis

Older People With Faster Decline in Memory and Thinking Skills May Have Lower Risk of Cancer Death

Long-Term Hormone Therapy Is Associated With Improved Survival in Women With Non‒Small Cell Lung Cancer

FDA Approves Ethiodized Oil Injection for Imaging of Tumors in Adults With Known Hepatocellular Carcinoma

ASCO Endorses SSO/ASTRO Guideline on Margins for Breast-Conserving Surgery With Whole-Breast Irradiation in Stage I and II Invasive Breast Cancer

Phase II Study Suggests Promise of Intermittent Chemotherapy Plus Continuous Cetuximab in Advanced KRAS Wild-Type Colorectal Cancer

Targeted Investigational Therapy Shows Anticancer Activity in Multiple Cancer Types

Consumptive Hypothyroidism in GIST Associated With Increased D3 Expression

Deep, Integrated Genomic Analysis Reclassifies Lower-Grade Brain Tumors

Study Identifies Frequent Cause of Breast Cancer Resistance to Investigational PI3K-Alpha Inhibitor

High Prediagnosis BMI Is a Predictor for Poor Outcome in Colorectal Cancer Patients, Overriding Tumor Marker Linked to Better Prognosis

Crossover Trial Indicates Preference for Pazopanib Over Sunitinib in Patients With Metastatic Renal Cell Carcinoma

Six Months Hormonal Treatment in Addition to Radiotherapy Improves Survival for Men With Localized Prostate Cancer

Investigational Bromodomain Inhibitor Shows Clinical Activity in Some Blood Cancers

Experimental Drug Shows Promise for Treatment-Resistant Leukemia

Preclinical Study Identifies Potential New Approach to Overcome Breast Cancer Resistance to HER2-Targeted Therapies

Study Identifies Potential Predictor of Clinical Outcome in Patients With Lung Cancer Treated With MK-3475

Phase I Trial of New Antibody-Drug Conjugate Shows Promise Against All Forms of Melanoma

Similar Progression-Free Survival With Panitumumab vs Bevacizumab Plus Modified FOLFOX6 in Wild-Type KRAS Exon 2 Metastatic Colorectal Cancer

Prognosis of HPV-Positive Head and Neck Cancer Varies According to Tumor Site

New Test Developed to Detect Men at High Risk of Prostate Cancer Recurrence

I-SPY 2 Results Identify Subset of Breast Cancer Patients Most Likely to Benefit From Neratinib

Investigational Drug Demonstrates Early Promise in Metastatic Breast Cancer

Biomarker Identifies Melanoma Patients Who May Respond to Immunotherapy MK-3475

High t(14;18) Translocation Frequency Predicts Follicular Lymphoma up to 15 Years Later

Palbociclib Plus Letrozole Achieves Impressive Results in Metastatic Breast Cancer

Tumor-Suppressor Gene TP53 Mutated in 90% of Osteosarcomas

Certain Genetic Variants May Help Identify Patients at Increased Risk of Bladder Cancer Recurrence

Study Implicates SMARCA4 Gene as Key Player in Oncogenesis of Small Cell Carcinoma of the Ovary

Validation of Mantle Cell Lymphoma International Prognostic Index in European Mantle Cell Lymphoma Network Trials

HLA Class I Antigen Expression Predicts Overall Survival Benefit With Aspirin Use in Colon Cancer

Dose-Escalated Hypofractionated IMRT for Localized Prostate Cancer Has Similar Side Effects Compared to Conventional IMRT

Long-Term Study Finds Fertility Drugs Do Not Increase Breast Cancer Risk

Findings of AURELIA Trial Support Consideration of Bevacizumab/Chemotherapy in Carefully Selected Patients With Platinum-Resistant Ovarian Cancer

Addition of Bevacizumab to Chemotherapy Improves Patient-Reported Outcomes in Platinum-Resistant Ovarian Cancer

Adding Bevacizumab to Chemotherapy Improves Progression-Free Survival in Platinum-Resistant Recurrent Ovarian Cancer

Study Finds Routine Mammograms Offer Limited Benefit to Oldest Female Patients

Lack of Insurance Coverage a Barrier to Lung Cancer Screening

Bendamustine/Rituximab May Be Important Alternative Treatment Option for Indolent Non-Hodgkin Lymphoma or Mantle Cell Lymphoma

18F-FDOPA PET Predicts Good Prognosis as Soon as 2 Weeks After Start of Antiangiogenic Therapy in Recurrent High-Grade Glioma

MET Immunohistochemistry Expression Is Best Predictor of Benefit From Addition of Onartuzumab to Erlotinib in Advanced NSCLC

Digital Mammography Reduces Recall and Biopsy Rates

Obesity Primes the Colon for Cancer, According to NIH Study

Patient Characteristics and Outcome Differ in Clinical Trial vs General Population Elderly Patients With Hormone Receptor–Positive Breast Cancer

DNA Test Can Help Predict Bladder Cancer Recurrence

Radiofrequency Ablation Reduces Risk of High-Grade Dysplasia and Adenocarcinoma vs Endoscopic Surveillance in Patients With Barrett’s Esophagus

Three-Dimensional MRI Scans May Offer More Accurate Way to Predict Survival After Chemotherapy for Liver Tumors

Study Finds Chemotherapy Accelerates Molecular Aging in Patients With Breast Cancer

Women Are Infrequently First or Corresponding Authors in Collaborative Group Publications in Oncology

Phase II Trial Shows Feasibility of Customized Adjuvant Treatment in NSCLC, but Phase III Trial Canceled Due to Unreliability of ERCC1 Readouts

Anastrozole Reduces Breast Cancer Incidence in High-Risk Postmenopausal Women

Experts Call for More Awareness of Sexual Dysfunction in Lung Cancer Patients

FDA Panel Endorses Stool-Based DNA Colon Cancer Test

Long-Term Benefit With Dasatinib After Imatinib Failure in Chronic-Phase CML

Ceritinib Highly Active in Patients With ALK-Rearranged Advanced NSCLC, Including Those With Prior Crizotinib Treatment

Metastatic Neuroblastoma Confined to Distant Lymph Nodes Associated With Better Survival Compared With Other Stage IV Disease

Gene Implicated in Progression and Relapse of Triple-Negative Breast Cancer

Prolonged Administration of Azacitidine Improves Response in Myelodysplasia, Less So in Combination With Entinostat

Electronic Cigarette Usage Associated With Use of Conventional Cigarettes Among Adolescents

Pemetrexed and Gemcitabine Show Promise Against Aggressive Childhood Brain Tumor

Tumor Size, Location, and Mitotic Rate, but Not Genotype, Associated With Recurrence-Free Survival in Trial of Adjuvant Imatinib vs Placebo in GIST

Continued Event-Free Survival Benefit of Neoadjuvant/Adjuvant Trastuzumab in HER2-Positive Locally Advanced Breast Cancer

Immunotherapy Data Herald New Era of Lung Cancer Treatment

Omitting Radiotherapy in Early PET-Negative Stage I/II Hodgkin Lymphoma Is Associated With Increased Risk of Early Relapse

Erlotinib and Gefitinib Offer Similar Benefit in EGFR-Mutated Non–Small Cell Lung Cancer

Phase III Study: Crizotinib Prolongs Progression-Free Survival in Previously Untreated ALK-Positive Advanced NSCLC

Locoregional Progression of Cervical Cancer Follows Reverse Ontogenetic Sequence

Phase II Study Suggests Benefit of Adding Rituximab to Chlorambucil in First-Line Treatment for Chronic Lymphocytic Leukemia

PARP Inhibitor Veliparib Might Benefit Women With Resistant Gynecologic Cancers and BRCA Mutation

Long-Term Use of Valproic Acid May Reduce the Risk of Head and Neck Cancer

Lymphedema Lingers Long After Sentinel Lymph Node Dissection for Early Breast Cancer

Long-Term Follow-up Shows Surgery Plus Radiation Offers Mixed Results in Soft-Tissue Sarcoma

Stool Multitarget DNA Test More Sensitive, But Less Specific Than Fecal Immunochemical Test for Colorectal Cancer Screening in Persons at Average Risk

ASCO Issues Updated Recommendations for Sentinel Lymph Node Biopsy in Early-Stage Breast Cancer

Study Finds Oncologists Have Mixed Attitudes on the Use of Genomic Testing

Risk Factors for Gastrointestinal Adverse Events Studied in Setting of First-Line Bevacizumab/Chemotherapy for Ovarian Cancer

Women With Gynecologic Cancers May Live Longer When Treated at High-Volume Medical Centers

Women With BRCA1 Mutations May Still Be at Risk for Rare Types of Uterine Cancer After Preventive Salpingo-Oophrectomy

Bariatric Surgery May Lower Risk of Uterine Cancer

Audit of NHS Breast Cancer Screening Programme Reveals Significant Variations Between Hospitals in Treatment Outcomes for DCIS

Harms Outweigh Benefits for Women Aged 70 and Over in National Breast Cancer Screening Programs

Investigational Cancer Vaccine Shows Renewed Potential in Non–Small Cell Lung Cancer

Obesity and Diabetes Have Adverse Effects on Outcomes Across Breast Tumor Types, Should Be Taken Into Account When Planning Treatment

Socioeconomic Disparities in Mortality After Cancer Surgery Reflect Higher Failure-to-Rescue Rates in Hospitals Treating More Low-Income Patients

Preclinical Study Suggests Benefits of Increased Tumor Perfusion and Reduced Tumor Hypoxia With Exercise in Prostate Cancer

Analysis of SWOG Trials Indicates No Survival Difference After 1 Year in Cancer Patients Treated In vs Out of Clinical Trials

Regular Physical Activity Reduces Breast Cancer Risk Irrespective of Age or Weight

Genetic Testing May Improve Selection of Women With Estrogen Receptor–Positive Breast Cancer for 10 vs 5 Years of Hormonal Therapy

Postmastectomy Radiotherapy Benefits Women With Breast Cancer That Has Spread to One to Three Lymph Nodes

Cutaneous Melanoma and Papillary Thyroid Carcinoma: Mutual Increased Risk

Swedish Study Shows Lower Prostate Cancer Mortality in High-Incidence Areas

High Circulating Tumor Cell Count at Baseline and Increases in Count During Treatment Linked to Reduced Survival in Metastatic Breast Cancer

Health Gap Between Adult Survivors of Childhood Cancer and Siblings Widens With Age

No Mortality Benefit From Primary Androgen-Deprivation Therapy for Most Men With Early-Stage Prostate Cancer

Shortening of Leukocyte Telomeres Associated With Increased All-Cause and Breast Cancer–Specific Mortality in Breast Cancer Patients

No Difference in Bone Mineral Density Changes With Adjuvant Exemestane vs Anastrozole in Women With Early Breast Cancer

American Association for Cancer Research Elects José Baselga, MD, PhD, as President-Elect 2014-2015

ASCO Urges Raising the Bar for Cancer Clinical Trials

Report Shows More Screening Has Led to a 30% Drop in Colon Cancer Rates

NCCN Cancer Survivorship Guidelines Expanded to Address Two Common Conditions

Circulating Tumor Cell Count and Early Change in Count Are Prognostic for Survival in First-Line Docetaxel Treatment of Prostate Cancer

No Overall Survival Benefit of First-Line Doxorubicin Plus Ifosfamide vs Doxorubicin Alone in Advanced Soft-Tissue Sarcoma

Surgical Resection Is Underutilized in Patients With Early-Stage Pancreatic Cancer, Study Finds

Lab Study Finds Pancreatic Cancer Growth Is Slowed by Blocking the Hhat Enzyme

NCCN Advocates for Universal Lynch Syndrome Screening in Newly Diagnosed Colorectal Cancer

Children With Cancer, Parents, and Providers Value Patient-Reported Outcomes Feedback

Stereotactic Body Radiation Costs Less but Is Associated With More Genitourinary Toxicity vs Intensity-Modulated Radiation Therapy for Prostate Cancer

Patient With Bladder Cancer Shows Exceptional Response to Everolimus/Pazopanib Combination

FDA Advisory Committee Unanimously Recommends HPV Test as Primary Screening Tool for Detection of Women at High Risk for Cervical Cancer

Only Small Number of Genetic Markers Show Association With Capecitabine Toxicity in Colorectal Cancer

Satisfaction With Work-Life Balance Among U.S. Oncologists Lower Than Other Medical Specialties, Survey Says

Antibody Could Be Used to Target Tumor-Enhancing Protein, Study Shows

Rituximab Maintenance Delays Need for Subsequent Treatment vs Watchful Waiting in Asymptomatic Nonbulky Follicular Lymphoma

Greater Interpretive Volume Leads to Greater Accuracy in Quebec Breast Cancer Screening Program

First Comprehensive Report on U.S. Cancer Care Finds Patient Access Threatened by Growing Demand, Physician Shortages

Study Finds CT Scans Predict Chemotherapy Response in Pancreatic Cancer

Study Examines Gene Expression of Adjacent Airway Field Cancerization in NSCLC

Pilot Study Shows Decision Aid Helps in Decision-Making Regarding Mammography Screening in Women Aged ≥ 75 Years

No Apparent Increased Risk of Myelodysplastic Syndrome With Definitive Radiotherapy in Prostate Cancer

Higher Macrophage Inhibitory Cytokine-1 Levels Associated With Increased Risk of Colorectal Cancer

Erlotinib Plus Cisplatin-Based Chemoradiation May Prolong Survival of Patients With Locally Advanced Cervical Cancer

IDH1-Mutant Malignant Astrocytomas May Be More Amenable to Surgical Resection and Linked to Better Prognosis

Continued Survival Benefits With Radical Prostatectomy in Longer-Term Follow-up in Scandinavian Prostate Cancer Group-4 Trial

Fertility Concerns Affect Treatment Choices in Young Women With Breast Cancer, but Few Use Preservation Options

High Bone Biomarker Levels Linked to Preferential Survival Benefit of Atrasentan in Castration-Resistant Prostate Cancer With Skeletal Metastases

Lung Complications Measured by Simple Questionnaire Predict Survival in Chronic Graft-vs-Host Disease

Nonmelanoma Skin Cancer Linked to Other Cancers, Especially in Young Survivors

No Benefit of Early Zoledronic Acid in Reducing Skeletal-Related Events in Castration-Sensitive Prostate Cancer With Bone Metastases

Correlation of PIK3CA Mutation and Neoadjuvant Lapatinib/Letrozole Response in Hormone Receptor–Positive, HER2-Negative Breast Cancer

Durable Tumor Responses With Nivolumab in Long-Term Follow-up of Patients With Advanced Melanoma

Epigenetic Imprint of Chemotherapy Linked to Inflammation in Breast Cancer Survivors

Novel Cancer Vaccine Shows Promise in Ovarian Cancer and Mesothelioma

Study Finds More Hospital Deaths and Invasive Care for Terminal Cancer Patients Receiving Palliative Chemotherapy

Trends in Phase III Trials in Advanced NSCLC: Decline in Use of Overall Survival as Primary Endpoint, More ‘Positive’ Outcomes

Same Progression-Free Survival, Better Quality of Life With Lower-Dose Weekly vs Every-3-Week Carboplatin/Paclitaxel in Advanced Ovarian Cancer

Common Cancers Evade Detection by Silencing Parts of Immune System Cells, Study Finds

Childhood Cancer Survivors at Very High Risk of Later Endocrine Disorders in Scandinavian Study

Blood Test Could Improve Treatment for Children With Late-Stage Neuroblastoma

Screening With Visual Inspection of Cervix After 4% Acetic Acid Could Reduce Cervical Cancer Mortality by 22,000 per Year in India

‘Real World’ Safety Study of Vemurafenib in BRAF V600–Mutated Metastatic Melanoma Shows Similar Safety Profile as Pivotal Trials

BPA Exposure May Be Linked to Prostate Cancer, Study Shows

Yoga Regulates Stress Hormones and Improves Quality of Life for Women With Breast Cancer Undergoing Radiation Therapy

Study Finds Possible New Gene Target for Lung Cancer

Intensity-Modulated Radiation Therapy Reduces PEG Tube Dependence and Severe Skin and Mucous Membrane Toxicity in Oropharyngeal Cancer

Meta-Analysis Shows Survival Benefit of Preoperative Chemotherapy in NSCLC

Study Identifies Possible New Target for Future Glioblastoma Drugs

No Overall Survival Advantage for Escalated-Dose vs Control-Dose Conformal Radiotherapy for Prostate Cancer at 10 Years

African Americans Have Higher Prevalence of Multiple Myeloma Precursor Than Whites and Hispanics

Early Palliative Care Benefits Patients With Advanced Cancer

Standard 24 Gy More Effective Than 4 Gy in Radiotherapy for Indolent Lymphoma

Robotic-Assisted Prostate Surgery May Offer Better Cancer Control Than Open Radical Prostatectomy

Tumor Protein Predicts Response to Chemotherapy in Patients With Esophageal Cancer

Lower Adenoma Miss Rate With Full-Spectrum vs Standard Forward-Viewing Colonoscopy

Anthropometric and Hormonal Factors Increase Risk for Male Breast Cancer

Reduced Risk of Cervical Lesions Among Girls and Women 6 Years After Licensure of HPV Vaccine in Denmark

Event-Free Survival at 24 Months Can Serve as Endpoint for Disease-Related Outcome in Diffuse Large B-Cell Lymphoma Treated With Immunochemotherapy

CAR T-Cell Therapy Yields Promising Complete Response Rates in Patients With Relapsed/Refractory B-Cell ALL

Adding Bevacizumab to Chemotherapy Improves Survival in Advanced Cervical Cancer

Bevacizumab Added to Radiotherapy/Temozolomide Improves Progression-Free Survival but Not Overall Survival in Newly Diagnosed Glioblastoma

Selenium and Vitamin E Supplements May Increase Risk of Prostate Cancer in Some Men

Large Study Shows Preventive Ovarian Surgery in BRCA1 Mutation Carriers Should Be Performed Early for Greatest Benefit

Methotrexate-Induced Neurotoxicity Does Not Preclude Rechallenge in Children With ALL

Rates of Breast Reconstruction After Mastectomy Increase, but Use Varies Widely According to Numerous Factors

Adding Bevacizumab to Radiotherapy and Temozolomide Does Not Improve Overall Survival in Newly Diagnosed Glioblastoma

Patient-Centered Outcomes Research Institute Develops Prioritized Research Agenda for the Management of DCIS

Hormone Therapy Associated With Improved Survival in Women With Non–Small Cell Lung Cancer

Natural Compound Attacks HER2-Positive Breast Cancer Cells

Minimal Pleural Effusion Predicts Poorer Survival in Non–Small Cell Lung Cancer

Final Report From Multicenter Selective Lymphadenectomy Trial Supports Sentinel-Node Biopsy for Thick and Intermediate-Thickness Melanomas

No Progression-Free Survival Difference for Dovitinib vs Sorafenib in Third-Line Targeted Treatment of Metastatic Renal Cell Carcinoma

Study Identifies Common Driver of a Childhood Brain Tumor

Oropharyngeal Cancer Patients Report Benefit in Salivary Function With Reduction of Radiation Dose to Bilateral Submandibular Lymph Nodes

Patients With Oropharyngeal Cancer Report Decreased Quality of Voice and Speech After Treatment

Unilateral Radiotherapy for Advanced Tonsil Cancer Yields Favorable Outcome

Avoiding Radiation to Major Salivary Glands in Head and Neck Cancer Is Safe and Improves Quality of Life

Pathologic Complete Response Has Prognostic Value in Breast Cancer, But Is Not Supported as Surrogate for Event-Free or Overall Survival

Proteomic Mucin Profiling More Accurate Than Cytology and CEA in Identifying Cystic Precursors of Pancreatic Cancer

Study Finds Combining a Novel Biomarker With HPV Status Predicts Patient Outcome in Head and Neck Cancer

Distant Metastases Occur Later and in More Subsites in Patients With HPV-Positive Squamous Cell Carcinoma of the Oropharynx

HPV-Positive Oropharyngeal Cancer Associated With Higher Overall Survival Rate After Progression Than HPV-Negative Disease

Use of Intravenous Pegaspargase in Adapted Pediatric Regimen Is Feasible in Adults With Newly Diagnosed ALL

Daily Humidification of the Mouth and Throat During Radiation for Head and Neck Cancer Reduces Mucositis

Molecular Features of Invasive Bladder Cancer Resemble Those of Breast Cancer

CD49d-Positivity Is the Strongest Flow Cytometry–Based Predictor of Overall Survival in CLL

New Finding Points to Potential Options for Targeting Stem Cells in Triple-Negative Breast Cancer

Nonsentinel Lymph Node Status Independently Predicts Melanoma-Specific Survival in Patients With Two or Three Positive Nodes

Study Identifies Key Mechanism Involved in Promoting Melanoma Proliferation

Age and Comorbidity Affect Completion of Adjuvant Trastuzumab Therapy in Older Patients With Early-Stage Breast Cancer

Rituximab Active in Nodular Lymphocyte–Predominant Hodgkin Lymphoma

Leukemia & Lymphoma Society Applauds FDA's Approval of Ibrutinib for CLL

Blacks, Hispanics, Older Americans Not Benefiting Equally From Improvements in Colon Cancer Treatment

Lenalidomide, Particularly When Combined With Oral Melphalan, Increases Risk of Second Primary Hematologic Malignancy in Myeloma Therapy

Researchers Discover Preleukemic Stem Cell at Root of AML Relapse

Compound Screening Identifies Novel Treatment Options for Gastrointestinal Stromal Tumors

Aspirin and NSAID Use Reduce Risk of Invasive Epithelial Ovarian Cancer

Omacetaxine Mepesuccinate Receives Full FDA Approval for CML

Normal Enzyme Pairs With Mutated FLT3 to Fuel AML Progression

No Difference in Recurrence After 5 Years With or Without Radiotherapy Following Sector Resection in Stage I Breast Cancer

Findings With Comparative Genomic Hybridization Array and DNA Sequencing Indicate Feasibility of Personalized Treatment for Metastatic Breast Cancer

No Mortality Benefit of Mammography Screening in 25-Year Follow-up of Canadian National Breast Screening Study

Study Identifies Possible Genetic Markers in Breast Cancer Brain Metastases

FDA Approves Ibrutinib for the Treatment of Chronic Lymphocytic Leukemia

Small Panel of FISH Cytogenetic Markers Distinguishes Risk in Medulloblastoma Subgroups

SSO-ASTRO Consensus Guideline: Margins Wider Than 'No Ink on Tumor' Do Not Further Reduce Risk of Ipsilateral Breast Tumor Recurrence

Extended Follow-up in BRIM-3 Shows Prolonged Survival With Vemurafenib in BRAF V600E/K Mutation–Positive Melanoma

Antifungal Itraconazole Shows Activity in Basal Cell Carcinoma

Researchers Identify Biomarker for Noncancerous Pancreatic Cysts

Novel Photon-Counting Technique Increases Detection Rate in Screening Mammography

Radiotherapy for Bulky Disease Added to R-CHOP Improves Outcome in Elderly Patients With Aggressive B-Cell Lymphoma

MicroRNA-181a Shows Promise as a Biomarker for Late-Stage Ovarian Cancer

Study Identifies Functional Cooperative Mutations of SETD2 in the Development of Acute Leukemia

Coordination of Care Improves Patient-Reported Quality of Supportive Care Among Patients With Colorectal Cancer

Promising Effects of High-Dose Parenteral Ascorbate in Ovarian Cancer

Crizotinib Produces Durable Responses in Small Study of Patients With Advanced, Chemoresistant ALK-Positive Lymphoma

PTX3 Haplotype in Donors Increases Risk of Invasive Aspergillosis in Stem Cell Transplantation

Brachytherapy Offers Lower Rate of Breast Preservation vs Standard Radiation for Older Women With Breast Cancer

Obesity Linked to Poor Survival in Patients With Tongue Cancer

Newly Created Risk Stratification Database Aids in Predicting Outcomes in Prostate Cancer

High Incidence of Complications Other Than Urinary Incontinence or Erectile Dysfunction After Prostatectomy or Radiotherapy for Prostate Cancer

Progression-Free Survival Can Be Used as Surrogate for Overall Survival in Metastatic Melanoma Trials With Dacarbazine Control Group

Hyaluronan Synthase 3 Variant Associated With Increased Risk of Anthracycline-Related Cardiomyopathy

Optimized Radiation Treatment Schedule for Glioblastoma May Extend Survival

Expressive Writing Improves Symptoms and Physical Function in Patients With Renal Cell Carcinoma

New Findings Contradict Current Understanding of How to Manage Breast Biopsy Abnormalities

Unfavorable Prognosis in Advanced Serous Ovarian Cancer May Be Linked to Estrogen Receptor Beta Isoform

Adjuvant Chemotherapy for Isolated Locoregional Recurrence of Breast Cancer Associated With Significantly Better Disease-Free and Overall Survival

Biomarker May Predict Response to Ipilimumab in Advanced Melanoma

Potential Therapeutic Role for Aspirin in the Management of Sporadic Vestibular Schwannoma

Bladder Cancer Study Uncovers Potential Drug Targets and Molecular Similarities to Other Cancers

Yoga Improves Inflammation, Fatigue, and Vitality in Breast Cancer Survivors

Higher Dietary Lycopene Intake Associated With Reduced Risk of Lethal Prostate Cancer and Reduced Tumor Angiogenesis

ASCO Issues New Recommendations for Family History-Taking in Oncology Setting

Cytoreductive Nephrectomy Improves Survival in Metastatic Renal Cell Carcinoma Patients With Longer Life Expectancy

Alternative Mechanism of Action Suggested for Vemurafenib in Hairy Cell Leukemia With BRAF V600E Mutation

Patients With Near-Complete Response After Induction Therapy May Be Candidates for Bladder-Sparing Therapy

Studies Evaluate Trends in the Surgical Management of Penile Cancer

Following USPSTF Mammography Screening Guidelines Could Save Billions of Dollars and Result in More Women Screened

Prostate Health Index May Provide New Tool to Identify Patients Assigned to Watchful Waiting Who Require Immediate Treatment

Prolonged Hormone Therapy Exposure Increases Risk of Diabetes and Cardiovascular Disease in Older Patients With Prostate Cancer

Study Examines Immunotherapy in Metastatic Castration-Resistant Prostate Cancer

New Society Launched for Advanced Practitioners in Hematology and Oncology

Improved Survival With Four-Drug Induction Regimen Followed by Maintenance in Initial Treatment of Transplant-Ineligible Multiple Myeloma

Study Reports Success in Targeted Therapy for Lung Adenocarcinoma

Is the Traumatic Impact of Cancer Overestimated in Children With Cancer?

Early Termination Not Unique to Genitourinary Cancer Clinical Trials

Angiotensin System Inhibitors Improve Survival in Hypertensive Patients With Metastatic Renal Cell Carcinoma

Radiation Plus Hormone Therapy Extends Survival in Patients With High-Risk Prostate Cancer

Enzalutamide Improves Survival in Chemotherapy-Naive Metastatic Castration-Resistant Prostate Cancer

New Clues May Link Hereditary Cancer Genes to Increased Risk of Cancer From Alcohol

Melatonin May Potentially Slow Tumor Growth in Estrogen Receptor–Negative Breast Cancers

New Mathematical Model Helps Predict Tumor Evolution and Treatment Effectiveness

Good Results With Telephone Genetic Counseling for Breast and Ovarian Cancer

Telephone-Based Intervention Improves Colorectal Cancer Screening in At-Risk Relatives of Patients With Colorectal Cancer

NCI Scientists Map Genetic Changes in Rhabdomyosarcoma Tumors

ASCO Survey of Oncologists Finds High Overall Career Satisfaction, but Nearly Half Report Burnout

PI3K-Delta Inhibitor Idelalisib Produces High Response Rates in Relapsed Indolent Lymphoma

Adding Idelalisib to Rituximab Improves Progression-Free and Overall Survival in Patients With Difficult-to-Treat, Relapsed CLL

Intensive Follow-up Increases Surgical Treatment of Recurrence With Curative Intent in Colorectal Cancer

Study Shows 20% of Women With Ovarian Cancer Have Inherited Genetic Mutations That Increase Risk of Disease

No Survival Benefit of Adjuvant 5-FU–Based Chemotherapy After Neoadjuvant Radiotherapy or Chemoradiation for Resectable Rectal Cancer

Dermoscopy Shows Characteristics of Cutaneous Metastases of Visceral Cancers

Cognitive-Behavioral Therapy Plus Hypnosis Controls Fatigue in Breast Cancer Patients Receiving Radiotherapy

Advanced Rai Stage Predicts Poor Outcome of Skin Cancer in CLL

Intensity-Modulated Radiation Therapy Improves Survival in Patients With Head and Neck Cancer

Model of Individualized Estimates Shows Risk of Overdiagnosis in Screening-Detected Prostate Cancers Varies Widely by Age, PSA, and Gleason Score

11-Protein Signature Distinguishes Good and Poor Outcome in Node-Negative, Adjuvant Therapy–Naive, Triple-Negative Breast Cancer

One-Fifth of Hospitalizations for Patients With Gastrointestinal Cancer Considered Avoidable

Afatinib Improves Progression-Free Survival vs Cisplatin/Gemcitabine in First-Line Treatment of Asian Patients With Advanced EGFR-Mutant NSCLC

Pilot Study Shows Promise of Neoadjuvant Chemotherapy Without Routine Radiotherapy in Patients With Locally Advanced Rectal Cancer

Study Questions the Anticancer Mechanism of Metformin

Long-Term/High-Dose Use of ACE Inhibitors Associated With Reduced Colorectal Cancer Risk in Hypertensive Subjects

Addition of Nintedanib to Docetaxel Improves Progression-Free Survival as Second-Line Treatment in NSCLC

Many Patients Have Some Pain 12 Months After Breast Cancer Surgery

High Prevalence of Platinum-Related Hearing Loss in Children With High-Risk Neuroblastoma, With Differences According to Audiometry Scales

Maintenance Capecitabine/Bevacizumab Delays Disease Progression in Metastatic Colorectal Cancer and Extends Survival in Subgroups

Adding Chemotherapy to Radiotherapy Does Not Appear to Affect Cognitive Function in Patients With Low-Grade Glioma

Seven-Gene Score Incorporating Methylation and Expression Distinguishes AML Risk Groups

Breast-Conservation Therapy Associated With Better Cancer-Specific Survival Than Mastectomy in Patients With Early-Stage Invasive Ductal Carcinoma

MicroRNA Test Reduces False-Positive CT Screening Rate for Lung Cancer

Irinotecan Drug-Eluting Beads Improve Outcomes in Colorectal Cancer Patients With Liver Metastases

Surgeon Experience Affects Likelihood of Sentinel Lymph Node Biopsy in Older Women With Breast Cancer

Cetuximab Fails to Improve Survival in Nonoperable Esophageal Cancer

Both Mindfulness-Based Stress Reduction and, More So, Cognitive Behavioral Therapy Improve Insomnia in Cancer Patients

Multiple Myeloma Study Shows Widespread Genetic Heterogeneity

Immunotherapy Strategy Boosts Survival in Metastatic Pancreatic Cancer

Ramucirumab Combination Improves Overall Survival After First Progression in Patients With Metastatic Gastric Cancer

High Presurgical Levels of Angiogenic and Growth Factors Are Associated With Poorer Survival After Gastric Resection

RAS Status Predicts Response to Second-Line Treatment With Panitumumab for Metastatic Colorectal Cancer

Preoperative Oral Capecitabine Chemotherapy Is Equivalent to Infusional 5-FU for Rectal Cancer

Combination Capecitabine/Temozolomide Appears Highly Effective in Patients With Treatment-Resistant Neuroendocrine Tumors

No Increased Risk of Local Recurrence After Breast-Conserving Surgery in Triple-Negative Breast Cancer in Single-Center Study

Superior Progression-Free Survival With Obinutuzumab/Chlorambucil vs Rituximab/Chlorambucil in Previously Untreated CLL With Coexisting Conditions

Smoking Prevalence Declines Among Health-Care Professionals

Dabrafenib Receives FDA Breakthrough Therapy Designation for BRAF-Mutated NSCLC

FDA Accepts New Drug Application for Idelalisib in Refractory Indolent Non-Hodgkin Lymphoma

Known Lung Cancer Oncogenes ALK and ROS1 May Also Drive Certain Colorectal Tumors

Quadrivalent HPV Vaccine Provides Poorer Protection in Women 18 and Older or With Abnormal Cytology

Ibrutinib Promising as Initial Therapy for Elderly Patients With CLL in Phase IB/II Trial

Short-Term Follow-up Reveals Suboptimal Pain Relief and Marked Pain Worsening in Ambulatory Cancer Patients

Nurse- and Gastroenterologist-Led Algorithm-Based Management Improve GI Symptoms After Pelvic Radiotherapy

Meta-Analysis Indicates No Reduction in Risk of Local or Distant Breast Cancer Recurrence With Preoperative Staging MRI

Chemotherapy Drug Shortages Threaten Quality of Treatment

Web-Based Self-Care Support and Communication Coaching Program Reduces Symptom Distress in Cancer Patients

Half of Patients With Stage I Pediatric Malignant Ovarian Germ Cell Tumors Can Be Spared Chemotherapy After Initial Surgery With Surveillance Strategy

FDA Approves Combination Therapy for Unresectable or Metastatic Melanoma With BRAF V600E/K Mutations

Major Decline in Lung Cancer Reported

Rates of New Lung Cancer Cases Drop in U.S. Men and Women

Sentinel Lymph Node Biopsy Associated With Survival Advantage in Merkel Cell Carcinoma

Good Results Using Loss of Major Molecular Response as Criterion for Restarting Tyrosine Kinase Inhibitor Therapy in CML

No Benefit of Adding Tirapazamine to Cisplatin Chemoradiation in Locally Advanced Cervical Cancer

Survey Finds Many General Internists Are Uncomfortable Caring for Adult Survivors of Childhood Cancer

Preclinical Study Suggests E-Cigarettes May Contribute to Lung Cancer in High-Risk Individuals

Higher Copayment Associated With Greater Discontinuation of and Nonadherence to Tyrosine Kinase Inhibitor Treatment in CML

No Survival Benefit of Erlotinib in EGFR-Unselected Patients With Nonprogressing Ovarian Cancer After Platinum Therapy

Renal Cell Carcinoma Onset at ≤ 46 Years Could Serve as Marker for Genetic Testing

ASCO Issues Statement in Response to American Cancer Society Report

Most Physicians Would Enroll in Hospice If They Were Terminally Ill With Cancer, Study Finds

Matched-Pairs Analysis Shows Better Survival With Allogeneic Transplantation vs Conventional Chemotherapy in Postremission Therapy for AML

Imprime PGG Added to Chemoimmunotherapy Shows Improved Outcomes in Advanced Lung Cancer Patients

Single Fractions of Radiation for Painful Bone Metastases May Be Noninferior to Multiple Fractions

No Survival Difference for Autologous vs Reduced-Intensity Conditioning Allogeneic Stem Cell Transplant in Chemotherapy-Sensitive Mantle Cell Lymphoma

Recurrent Ovarian Cancers Respond to Cancer Vaccine After ‘Reprogramming’ With Decitabine

‘Faster and Deeper Responses’ With Dasatinib vs Imatinib in Chronic-Phase CML Patients

Phase II Pilot Study Does Not Support Phase III Investigation of IV High-Dose Interferon Without Maintenance in Resected Melanoma

Study Evaluates Risk of Depression by Race and Sex Among Patients With Newly Diagnosed Lung Cancer

No Difference for Aprepitant vs Dexamethasone for Chemotherapy-Induced Delayed Emesis in Patients With Breast Cancer

Imiquimod 5% Cream Inferior to Surgical Excision in Nodular and Superficial Basal Cell Carcinoma

Oral Insulin Sensitizers Associated With Decreased Cancer Risk in Women With Type 2 Diabetes

Neoadjuvant Paclitaxel Before Anthracycline Improves Response in High-Risk Early Breast Cancer

Science Magazine Names Cancer Immunotherapy as Scientific Breakthrough of the Year

FDA Approves Revised Prescribing Information for Ponatinib, Authorizes Resumption of Drug Sales and Distribution

Wider Surgical Margins Do Not Appear To Reduce Local Recurrence Rates in Triple-Negative Breast Cancer

Oral Ibandronic Acid Is Not Noninferior to IV Zoledronic Acid in Preventing Skeletal-Related Events in Patients With Breast Cancer

Low-Dose CT Screening May Result in Overdiagnosis of Lung Cancer

Sustained Complete Responses With Novel Immunotherapy in Lymphoma

Julie M. Vose, MD, MBA, FASCO, Elected ASCO President for 2015-2016 Term

Anti–PD-1 Antibody Pidilizumab Plus Rituximab Shows High Activity in Relapsed Follicular Lymphoma

No Survival Benefit for Tecemotide After Chemoradiotherapy in Stage III NSCLC

EUROCARE-5: Trends in Survival for Childhood Cancers

EUROCARE-5 Shows Increased Cancer Survival and Persisting Regional Disparities

U.S. Cancer Death Rates Continue Decline, Annual Report Shows

Younger Women With Younger Children Less Likely to Receive Radiation Therapy After Breast-Conserving Surgery for Breast Cancer

No Overall Survival Benefit With Addition of Sunitinib to Prednisone in Metastatic Castration-Resistant Prostate Cancer

Low hENT1 Is Associated With Poorer Survival in Patients With Pancreatic Cancer Receiving Adjuvant Gemcitabine

Suboptimal Adverse Event Reporting in Cancer Clinical Trial Publications

Dasatinib/Letrozole Drug Combination Delays Disease Progression in Hormone Receptor–Positive, HER2-Negative Metastatic Breast Cancer

Protective Effect of Aspirin for Colorectal Cancer Is Associated With rs6983267 T Allele

Second-Line Therapies May Benefit Patients With Castration-Resistant Prostate Cancer and Poor Performance Status

Novel BRAF Fusions Identified in 'Pan-Negative' Melanomas

Final Overall Survival Analysis of CONFIRM Trial Shows Advantage of Higher Dose of Fulvestrant in Advanced Breast Cancer

Biologic Mechanism May be Linked to Racial Disparities in Prostate Cancer

No Benefit of Calcium/Magnesium in Preventing Oxaliplatin-Induced Sensory Neurotoxicity in Patients With Colon Cancer

CALGB 40603 Trial Supports Adding Carboplatin to Neoadjuvant Chemotherapy in Triple-Negative Breast Cancer

Survival Benefit With High-Dose Cytarabine Induction in AML Patients Aged < 46 Years

Adjuvant Bisphosphonates Improve Breast Cancer Survival, Reduce Bone Recurrence in Postmenopausal Women With Early Disease

Adjuvant Paclitaxel/Trastuzumab Tolerable, Benefits Women With Stage I HER2-Positive, Node-Negative Breast Cancer

PIK3CA Mutations Predictive of Resistance to Neoadjuvant Therapy in HER2/HR-Positive Breast Cancers

Nonsignificant Reduction in Breast Cancer Risk Seen With Low-Dose Tamoxifen in Postmenopausal Hormone Replacement Therapy Users

Increased Cardiovascular Risk Despite Healthier Lifestyle Characteristics in Hematopoietic Cell Transplant Survivors

Fractionated 90Y-Ibritumomab Tiuxetan Radioimmunotherapy Produces High Response Rate in Initial Therapy for Follicular Lymphoma

Anastrozole Reduces Primary Breast Cancer Incidence by More Than 50% in High-Risk Postmenopausal Women

Less Is More: Postoperative Radiation May Be Avoided in Older Women With Estrogen Receptor–Rich Tumors

NeoALTTO Trial Links Pathologic Complete Response to Clinical Outcomes

Addition of Bevacizumab Fails to Improve Invasive Disease-Free Survival vs Adjuvant Chemotherapy/Trastuzumab Alone in HER2-Positive Breast Cancer

Benefit of Breast Cancer Screening More Consistent Across Studies Than Previously Understood

High Levels of Immune Cells in Tumors May Identify Breast Cancer Patients Most Likely to Benefit From Trastuzumab

ASH 2013: Brentuximab Vedotin Shows Promising Activity in Non-Hodgkin Lymphoma

No Difference in PFS for Temsirolimus vs Sorafenib as Second-Line Therapy After Sunitinib in Metastatic RCC

No Difference Between Temsirolimus/Bevacizumab vs Interferon Alfa/Bevacizumab in First-Line Therapy for Metastatic Renal Cell Carcinoma

Study Explores Risk of New Primary Melanomas After Diagnosis of Stage III/IV Melanoma in Patients Not Receiving BRAF Inhibitors

Ibrutinib/Rituximab Combination Leads to High Response Rate Among Patients With CLL

Elevated Plasma Vitamin B12 Levels Associated With Cancer Risk

Biologic Doublet a Potential Front-Line Treatment in Mantle Cell Lymphoma

Updated Myeloma Trial Shows Lenalidomide Maintenance Post-Transplant Improves Progression-Free But Not Overall Survival

Circulating Inflammation Markers Associated With Risk of Lung Cancer

Higher Levels of HSET Linked to More Aggressive Breast Cancers and Worse Outcomes in African American Women

Choosing Wisely® Initiative Improves Quality and Cost of Care

Idelalisib Achieves High Response Rates in 'Double-Refractory' Indolent NHL

Continuous Lenalidomide/Low-Dose Dexamethasone Improves Survival vs Standard Treatment in Older Patients With Newly Diagnosed Myeloma

Gemtuzumab Ozogamicin Reduces Relapse, Improves Event-Free Survival in Pediatric AML

Long-Term Symptoms Beyond 10 Years Experienced by Prostate Cancer Survivors

Novel Agents IPI-145 and ABT-199 Show Encouraging Results in Phase I CLL Studies

Obinutuzumab/Chlorambucil Superior to Rituximab/Chlorambucil as First-Line Treatment for Older CLL Patients With Comorbidities

Reduced-Intensity Hematopoietic Stem Cell Transplant Spares Cognition

Successful Chimeric Antigen Receptor–Expressing T-Cell Treatment Reported in Advanced Lymphomas

Graft Manipulation Improves HLA-Haploidentical Hematopoietic Stem Cell Transplant Outcomes

Vorinostat Plus Standard Immunoprophylaxis Cuts Risk of Graft-vs-Host Disease in Half

Grade 3 Endometrioid Carcinoma With PIK3CA Mutation Linked to Unfavorable Outcome

Genetic Mutation May Play a Role in Worse Outcomes for Obese Prostate Cancer Patients

Reduced Renal Function Observed in Patients Taking Crizotinib for Non‒Small Cell Lung Cancer

Preoperative MRI Assessment of Circumferential Resection Margin Predicts Survival and Local Recurrence in Rectal Cancer

Hypercholesterolemia May Drive the Growth of Breast Cancer

Disease-Free Survival Is Acceptable Surrogate for Overall Survival in Trials of Adjuvant Chemotherapy for Gastric Cancers

Eight-Gene Profile Predicts Benefit of Adjuvant Trastuzumab in HER2-Negative Disease

PPM1D Mutations in Circulating White Blood Cells Associated With Risk of Ovarian Cancer, Increased Mortality, and Risk of Breast Cancer

Nonsignificant Survival Benefit With Postoperative Radiation Therapy for Head and Neck Cancer at Academic Center vs Other Institutions

Digital Breast Tomosynthesis Increases Cancer Detection and Reduces Recall Rates

Over-Regulation of Opioids Is Resulting in Untreated Cancer Pain for Millions of Patients Worldwide

Three-Drug Regimen Produces High Response Rate in Relapsed/Refractory Multiple Myeloma

Maintained Oral Intake and Swallowing Exercise Adherence During Radiation Therapy Improve Long-Term Swallowing Outcomes for Pharyngeal Cancer Patients

Nurse Navigators Improve Patient-Reported Quality of Care in Early Cancer Care

Postradiotherapy Neck Dissection Improves Local Control in Head and Neck Squamous Cell Carcinoma Patients With Advanced Nodal Disease

U.S. Preventive Services Task Force Issues Final Recommendations on Screening for Oral Cancer

Interim Phase I/II Clinical Trial Data for VAL-083 Show Clinical Activity in Refractory Glioblastoma

Low-Fat Diet and Fish Oil Supplementation Reduces Cell-Cycle Progression in Prostate Cancer

Thyroid Ultrasound Strategy Identifies Low-Risk Patients Who Can Defer Biopsy

Reduced Specialist Consultation and Multimodality Therapy May Account for Poorer Survival in Black Patients With Metastatic Colorectal Cancer

Certain Symptom Clusters After Surgery for Esophageal Cancer Predict Poor Prognosis

ASCO Endorses Cancer Care Ontario Guideline for Follow-up in Colorectal Cancer Survivors

Estrogen Levels Affect the Efficacy of PARP Inhibitors in PTEN-Deficient Endometrial Tumors

Further Improvement Needed in Breast MRI Use in Community Practice

Increase in Breast MRIs Does Not Reflect Recommendations for Appropriate Use

FDA Approves Sorafenib to Treat Late-Stage Differentiated Thyroid Cancer

Epigenetic Modification of HAND2 May Be Associated With the Development of Endometrial Cancer

Study Finds Possible Link Between Allergies and Increased Risk of Hematologic Cancers in Women

PIK3CA Mutation Fails to Predict Outcome of Irinotecan-Based Therapy in Stage III Colon Cancer

Increasing Proportion of Head and Neck Cancer Patients Treated at Teaching Hospitals

12-Gene Recurrence Score Independently Predicts Recurrence in Patients With Stage II/III Colon Cancer

Smoking Increases Risk of Death for Nasopharyngeal Carcinoma Survivors

Internet-Based Intervention Improves Cancer-Related Sexual Dysfunction in Women

Brentuximab Vedotin Plus ABVD or AVD Is Highly Active in Newly Diagnosed Hodgkin Lymphoma

Studies Reveal Multiple Gene Alterations Responsible for Drug Resistance in BRAF-Mutated Melanoma

New Studies Provide Insight Into Melanoma Drug Resistance Pathways and Strategy for Obtaining Durable Responses

FDA Grants Regular Approval to Crizotinib for ALK-Positive NSCLC

Tasquinimod May Improve Survival in Men With Metastatic Prostate Cancer

Gemtuzumab Ozogamicin Reduces Minimal Residual Disease in Children With High-Risk Acute Myeloid Leukemia

MicroRNA Signature Predicts Risk of Recurrence After Surgery for Stage II Colon Cancer

Predictors of Sentinel Lymph Node Metastasis Identified in Thin Melanomas

STAT3 Activation Is Associated With Poor Survival in Diffuse Large B-Cell Lymphoma Treated With R-CHOP

Targeted Intraoperative Radiotherapy Concurrent With Lumpectomy Noninferior to External-Beam Radiotherapy in Preventing Local Breast Cancer Recurrence

No Advantage of Concurrent vs Sequential Trastuzumab/Anthracycline Neoadjuvant Therapy in Patients With HER2-Positive Breast Cancer

Prognostic Model Predicts Metastatic Castration-Resistant Prostate Cancer Survival in Second-Line Chemotherapy After Docetaxel

Additional Interim Data for Lambrolizumab Show Survival Benefit for Patients With Advanced Melanoma

Alternate VEGF Ligands Associated With Bevacizumab Resistance in Metastatic Colorectal Cancer

Most Patients Experience Nocturnal Care Disturbances Following Hematopoietic Stem Cell Transplantation

Timing and Choice of Treatment May Affect the Quality of Life of Young Breast Cancer Survivors

U.S. Pancreatic Cancer Death Rates Increasing in White Adults, Decreasing in Black Adults

International Ki67 Reproducibility Study Shows High Intralaboratory but Only Moderate Interlaboratory Reproducibility

No Overall Increased Risk of Cancer in Children Born After Assisted Conception in UK

No Benefit From Adding Cetuximab to Pemetrexed in Recurrent/Progressive NSCLC After Platinum-Based Therapy

Number and Distribution of Childhood Nevi Predict Melanoma in Subjects From Families With Familial Melanoma

Surgical Management of Male Breast Cancer Differs Dramatically From That of Female Breast Cancer

Intraoperative Radiotherapy Inferior to External Radiotherapy in Preventing Local Recurrence in Early Breast Cancer

Prognostic Score Predicts Overall Survival in Older Patients With Hodgkin Lymphoma by Second-Line Treatment Strategy

Dasatinib Plus Docetaxel Does Not Improve Overall Survival in Men With Chemotherapy-Naive Metastatic Castration-Resistant Prostate Cancer

Study Explains Cyclophosphamide’s Role in Preventing Graft-vs-Host Disease

Assay-Sensitive Treatment Improves Outcomes in Recurrent Ovarian Cancer

FDA Approves Ibrutinib for Mantle Cell Lymphoma

Personal History of Prostate Cancer Increases Risk of Melanoma

Persistent Significant Neurocognitive Impairment in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Increased Prevalence but Reduced Mortality of Venous Thromboembolism After Major Cancer Surgery

Young Breast Cancer Patients With Poorer Financial Status May Experience Delays in Seeking Care

Basaloid Squamous Cell Carcinoma Not Predictive of Worse Outcome vs Squamous Cell Carcinoma in Head and Neck Cancer

Statin Use Reduces Cancer-Specific and All-Cause Mortality in Patients With Nonmetastatic Prostate Cancer

Novel Oncogenetic Classifier Identifies Low- and High-Risk Patients With Adult T-Cell Acute Lymphoblastic Leukemia

Pegfilgrastim Prophylaxis Throughout Chemotherapy Is More Effective in Preventing Febrile Neutropenia in Breast Cancer (and More Costly)

Less-Invasive Endoscopic Therapy as Effective as Esophagectomy in Early Esophageal Cancer

New Mutation Found in the Estrogen Receptor May Cause Resistance to Breast Cancer Treatment

Phase II Trial of Ponatinib Shows Activity in Heavily Pretreated CML and Philadelphia Chromosome–Positive ALL

Novel Agents Produce Encouraging Trends in Gastric Cancer

HPV Screening Better Than Cytology in Preventing Invasive Cervical Cancer

Novel Oral Agent Extends Survival in Relapsed/Refractory Colorectal Cancer, Phase II Study Shows

Vemurafenib Produces Rapid Responses in Hairy Cell Leukemia

Imaging Studies May Predict Tumor Response to Antiangiogenic Drugs

Increased Use of Local Excision to Treat Early-Stage Rectal Cancer

Description of Ductal Carcinoma In Situ Affects Reported Treatment Preferences

Early Autologous Transplantation Improves Progression-Free Survival in Aggressive Non-Hodgkin Lymphoma

FDA Approves Transducer Array Layout System for Use in Patients With Recurrent Glioblastoma Multiforme

Atorvastatin May Prevent Graft-vs-Host Disease in Allogeneic Stem Cell Transplant Recipients

Most Gastroenterologists and Endoscopy Nurses Prefer Propofol Over Moderate Sedation in Screening Colonoscopies, but Would Pay Little Extra for It

Investigational Anti–PD-1 Immunotherapy Provides Durable Objective Responses in Patients With Previously Treated NSCLC

Contemporary Breast Radiation Therapy Associated With Lower Risk of Major Coronary Events

Measuring Hormone Levels Could Improve Risk Assessment for Breast Cancer

One Dose of HPV 16/18 Vaccine Produces Durable Response Against New Infections

FDA Approves Obinutuzumab for Chronic Lymphocytic Leukemia

Sale of Ponatinib Suspended Due to Risk of Life-Threatening Blood Clots

Teenagers and Young Adults Diagnosed With Cancer Are at Increased Risk of Suicide

Palliative Care Services and Outcomes Improve Using a Standardized Approach

Online Training Tool Can Improve Pathway Adherence and Reduce Costs

High-Volume Aerobic and Resistance Exercise May Help Reduce Decline in Physical Function During Chemotherapy for Breast Cancer

Nivolumab Shows Activity in Ipilimumab-Refractory or -Naive Melanoma in Phase I Trial

New ASCO Choosing Wisely® List Details Five Cancer Tests and Treatments Routinely Performed Despite Lack of Evidence

Investigational ALK Inhibitor Shows Promise in Patients With Crizotinib-Refractory, ALK-Positive Non–Small Cell Lung Cancer

Pemetrexed Improves Progression-Free Survival vs Gefitinib in Second-Line Setting for EGFR Wild-Type Nonsquamous NSCLC

Computer-Aided Diagnosis Tool Might Help Distinguish Small Lung Cancer Nodules From Benign Nodules

Long-Distance Travel for Cancer Care Is Linked to Later-Stage Breast Cancer Diagnosis

No Progression-Free Survival Difference With First-Line Axitinib vs Sorafenib in Metastatic Renal Cell Carcinoma

Problematic Symptoms After Prostate Biopsy Associated With Anxiety

African American Women Are Less Likely to Benefit From HPV Vaccines for Cervical Cancer Prevention

Prolonged Sedentary Behavior Linked to Recurrence of Precancerous Colorectal Tumors in Men

Shortened Telomeres in Blood Leukocytes May Be Associated With Increased Risk of Aggressive Prostate Cancer

New Biomarker May Differentiate Progressive From Nonprogressive Ductal Carcinoma in Situ

Multiple Myeloma Defined by Light Chain Amyloidosis With Plasma Cell or CRAB Criteria

Dose-Limiting Late Toxicity Observed After Hypofractionated Dose-Escalated Radiotherapy in NSCLC

Urologist Ownership of Intensity-Modulated Radiation Therapy Services Significantly Increases Use of Treatment for Prostate Cancer

FDA Approves First Extended-Release, Single-Entity Hydrocodone Product

The Impact of the Affordable Care Act on Oncology Care

Complete Sequencing of All Known Breast Cancer Genes Explains Occurrence of the Cancer in Women With Normal BRCA Genes

Novel Gene-Diet Interaction May Explain Association Between Red and Processed Meat Consumption and Colorectal Cancer Risk

Oral Contraceptives Linked to Reduced Risk of Ovarian Cancer and Nonsignificantly Increased Breast Cancer Risk in Women With BRCA1/2 Mutation

Study Clarifies Value—and Limitations—of Patient Assistance Programs for Women With Breast Cancer

Bone Marrow Transplant Linked to Negative Sexual Side Effects in Both Men and Women

Combining Metformin With Chemotherapy and Radiation May Improve Outcomes in Lung Cancer Patients

Report of Pancreatic Atrophy in Two Patients Receiving Long-Term Sorafenib

Perioperative FOLFOX4 Does Not Improve Overall Survival vs Surgery Alone in Patients With Resectable Liver Metastases From Colorectal Cancer

Addition of Nab-Paclitaxel to Gemcitabine Improves Survival in Previously Untreated Metastatic Pancreatic Cancer

New Biomarker May Help Guide Treatment of Melanoma Patients

New Molecular Diagnostics Platform Enables Rapid Detection of BRAF V600 Mutations

FDA Grants Priority Review to Ramucirumab as a Potential Single-Agent Treatment for Advanced Gastric Cancer

Phase II Study Supports Axitinib Dose Titration in Select Treatment-Naive Metastatic Renal Cell Carcinoma Patients

Robust Activity Shown for Investigational PARP Inhibitor BMN673 in BRCA-Related Cancers

Association Between Prevalence of Symptoms and Impaired Health-Related Quality of Life in Adult Survivors of Childhood Cancer

Sequential Addition of Gemtuzumab Ozogamicin to Standard Chemotherapy of No Benefit in Older Patients With Newly Diagnosed AML

Imatinib Rechallenge Slows Disease Progression in Patients With Metastatic or Unresectable GIST After Imatinib and Sunitinib

Investigational Antibody-Drug Conjugate May Provide New Treatment Option for Pancreatic Cancer Patients

Novel Drug Combinations Targeting Pathways Triggered by KRAS May Benefit Patients With Pancreatic Cancer

New Nanopharmaceutical May Be Able to Overcome Resistance to Antiangiogenic Treatment

Long-Term Obesity Is Linked With Poorer Pancreatic Cancer Survival

Targeted Investigational Therapy Has Potential to Overcome Crizotinib Resistance in Lung Cancers

Potential New Drug Effective in Breast Cancer and Melanoma Resistant to Targeted Therapies

Investigational EGFR Inhibitor May Hold Promise for Some Patients With Treatment-Resistant NSCLC

Risk of Congestive Heart Failure Increased With Trastuzumab Use in Older Breast Cancer Patients

Addition of Vintafolide to Pegylated Liposomal Doxorubicin Improves Progression-Free Survival in Platinum-Resistant Ovarian Cancer

FDA Investigating Ponatinib After Increased Reports of Serious Blood Clots in Arteries and Veins

NIH Awards $17 Million in Grants to Augment Genomics Research in Africa

Targeting Integrin β3-Src Pathway May Be Potential Strategy for Overcoming Anti-IGF-1R Antibody Resistance

Most Common Tumors Are Driven by Two to Six DNA Mutations

Improved Progression-Free but Not Overall Survival With Addition of Maintenance Erlotinib to Bevacizumab After Chemotherapy Plus Bevacizumab in NSCLC

Increased Radiation Dose With Hypofractionated vs Conventional Radiation Therapy Does Not Improve Biochemical/Clinical Failure Rate in Prostate Cancer

STAG2 Mutation Found Linked to Low-Risk Bladder Cancer

Researchers Identify Four Genetic Variants Linked to Esophageal Cancer and Barrett’s Esophagus

Inflammatory vs Noninflammatory Breast Cancers of Same Estrogen Receptor Status Have Varying Risk Factor Associations

Improvements Needed in Use of Survivorship Care Plans

Increased Risk of Long-Term Cardiovascular Mortality and All-Cause Mortality in Patients With Differentiated Thyroid Carcinoma

Simple Blood Test May Diagnose Lung and Other Cancers

Optical Metabolic Imaging Can Identify Breast Cancer Subtypes and Early Treatment Response

Dual-Stained Cytology Has Greater Sensitivity and Comparable Specificity vs Pap Cytology for High-Grade Cervical Intraepithelial Neoplasia

Breast Cancer Risk Differs by Race, BMI, Breast Density Among Hormone Replacement Therapy Users

RTOG 0525 Subanalysis Finds Worse Outcomes With Dose-Dense vs Standard Adjuvant Temozolomide in Glioblastoma

No Benefit of Dose-Dense vs Standard Temozolomide in Newly Diagnosed Glioblastoma, MGMT Methylation Associated With Better Survival

Standard and Reduced High-Dose Volume Radiation Therapy for Muscle-Invasive Bladder Cancer Have Comparable Tumor Control

LAT Inhibition May Be a New Therapeutic Option for Metastatic Castration-Resistant Prostate Cancer

Better Leukemia-Free and Overall Survival in AML in First Remission With Cyclophosphamide Plus Busulfan vs Total-Body Irradiation

Similar High Complete Response Rate With Neoadjuvant Trastuzumab, Lapatinib, and Combined Therapy in HER2-Positive Breast Cancer

No Additional Benefit of Venlafaxine or Soy Protein vs Placebo on Hot Flashes in Men With Prostate Cancer

Promising Outcomes With R-MPV Followed by Consolidation Reduced-Dose Whole-Brain Radiotherapy and Cytarabine in Newly Diagnosed Primary CNS Lymphoma

Women With Lower Pretreatment Estrogen Levels at Greater Risk of Breast Cancer During Estrogen-Plus-Progestin Therapy

Outcome Improved in MET-Positive and Worsened in MET-Negative NSCLC With Addition of Onartuzumab to Erlotinib in Phase II Trial

PAM50 Risk of Recurrence Score Provides Strongest Prognostic Information for Risk Beyond 5 Years in Estrogen Receptor–Positive Breast Cancer

Patients With Melanoma Do Not Maintain Cautious Behavior About Limiting Exposure to UV Radiation From the Sun

Gemcitabine Improves Overall Survival Following Surgery for Pancreatic Cancer

Program Chairs Highlight Abstracts of Interest for the 2013 CTRC-AACR San Antonio Breast Cancer Symposium

Substantial Proportion of Older Patients Receiving First-Line Chemotherapy Experience Functional Decline

Etirinotecan Pegol Active in Patients With Previously Treated Metastatic Breast Cancer

Patients With Poor Nutritional Status Before Radical Cystectomy Have a Higher Risk of Postoperative Complications

Researchers Identify Potential New Drug for Inherited Cancer

ACOSOG Z1071 Trial Does Not Support Sentinel Lymph Node Surgery Following Neoadjuvant Chemotherapy for Node-Positive cN1 Breast Cancer

Study Identifies Prognostic DNA Methylation Signature for Stage I NSCLC

Everolimus Does Not Improve Overall Survival in Previously Treated Advanced Gastric Cancer

ASCO and the College of American Pathologists Issue Updated Guideline on HER2 Testing in Breast Cancer

PIK3CA Mutation Predictive of Relapse-Free Survival Benefit of Aspirin in Colorectal Cancer

Study Assesses Frequency of Allogeneic Hematopoietic Cell Transplantation in Patients With AML in First Complete Remission

Radiotherapy After Local Excision for DCIS Reduces Long-Term Risk of Local Recurrence

Intervention Program Improves Sun Protection Practices Among Children of Melanoma Survivors

Increased Physical Activity and Walking Reduces Breast Cancer Risk

Etirinotecan Pegol Shows Activity in Recurrent Platinum-Resistant/Refractory Epithelial Ovarian Cancer

Poorer Overall Survival With Sunitinib vs Sorafenib in Advanced Hepatocellular Cancer

Older Cancer Survivors in Rural Areas Forgo Health Care Due to Cost

Ramucirumab Prolongs Survival in Advanced Gastric Cancer

Long-Term Follow-up Indicates Increased Telomere Length With Lifestyle Change in Men With Low-Risk Prostate Cancer

Flow Cytometric Residual Disease Highly Prognostic in Older AML Patients

Flow Cytometric Minimal Residual Disease Highly Prognostic in AML Patients Aged Under 60

BRCA1 and BRCA2 Mutation Carriers Not at Greater Risk of Earlier Natural Menopause

Long-Term Survivors of Childhood Cancer Exhibit Vascular Endothelial Damage

Lactation May Be Linked to Triple-Negative Breast Cancer in Mexican Women

Genetic Anti-Inflammatory Defect May Predispose Children to Lymphoma

Breast Cancer Rates Are Rising Among African American Women

Oral CMX001 100 mg Twice Weekly Reduces Cytomegalovirus Events in Patients Receiving Hematopoietic Cell Transplants

Addition of Rituximab Does Not Improve Outcome in Aggressive B-Cell Lymphoma With Skeletal Involvement, but Radiotherapy Benefit Found

ASCO Releases Statement on the Impact of the Government Shutdown on Cancer Care

ECC 2013: French Study Finds Routine PSA Screening Does More Harm Than Good

Treatment With Losartan May Improve Delivery of Chemotherapy Drugs in Tumors

Long-Term Results of UK START Trials Support Hypofractionated Adjuvant Radiotherapy in Invasive Early Breast Cancer

ECC 2013: Strong Showing for Ado-Trastuzumab Emtansine in Heavily Pretreated Advanced HER2-Positive Breast Cancer

ECC 2013: TP53 Status Predicts Benefit From Neoadjuvant Cetuximab in Rectal Cancer

ECC 2013: PI3KCA-Mutant Tumors Not Likely to Respond to Neoadjuvant HER2 Blockade

ECC 2013: Novel Anti-PD-L1 Antibody Achieves Durable Responses in Phase I Study of Patients With Metastatic NSCLC, Smokers Included

Men With Advanced Prostate Cancer Worry More About Burdening Family and Friends Than Dying, Survey Finds

ECC 2013: Continuous Combined Hormone Replacement Therapy Protects Against Endometrial Cancer

ECC 2013: Radiation to Chest Lymph Nodes Improves Survival in Early Breast Cancer

FDA Approves Neoadjuvant Pertuzumab for Early-Stage Breast Cancer

ECC 2013: Molecular Sequencing Identifies Drug Targets for Cancers of Unknown Primary Origin

ECC 2013: Multiple Studies Validate Long-Term Survival Benefit of Ipilimumab in Melanoma

Telomere Length May Be a Prognostic Marker for Prostate Cancer

Repurposed Antidepressants May Have Potential to Treat Small Cell Lung Cancer

Addition of Vorinostat to Bortezomib Results in Small Progression-Free Survival Advantage in Previously-Treated Multiple Myeloma

Intensity-Modulated Radiotherapy Associated With Superior Overall Cosmesis at 5 Years in Patients With Early Breast Cancer

Denosumab Increases Bone Metastasis-Free Survival According to PSA Doubling Time in Men With Nonmetastatic Castration-Resistant Prostate Cancer

ASTRO: Protecting Hippocampus During Whole-Brain Radiation Substantially Reduces Rate of Memory Loss in Cancer Patients

For Pregnant Women With Lymphoma, Standard Combination Chemotherapy Given After First Trimester Associated With Few Complications

Increases in Melanoma Incidence and Mortality Unremitting Over 6 Decades, Study Finds

Higher Post-Treatment FDG-PET Standardized Uptake Value Associated With Poorer Survival in Locally Advanced NSCLC

ASTRO: Intensity Modulated Proton Therapy May Preserve Quality of Life in Patients With Oropharyngeal Cancer

Pomalidomide Produces ‘Impressive Results’ in Patients With Multiple Myeloma Who Are Refractory to Bortezomib and Lenalidomide

Sunscreen Use Infrequently Discussed With Patients, Even Those With History of Skin Cancer

Abiraterone Acetate/Prednisone Combination Delays Decline in Quality of Life in Men With Metastatic Prostate Cancer

Large Retrospective Study Finds Association Between Marriage and Cancer Outcomes

Phase II Study Shows Activity of Selective Aurora A Kinase Inhibitor Alisertib in Relapsed/Refractory Aggressive B- and T-Cell Non-Hodgkin Lymphoma

Colonoscopy Associated With Reduction in Overall, Distal, and Proximal Colorectal Cancer Incidence and Mortality

Mindfulness-Based Stress Reduction Superior to Supportive-Expressive Therapy for Distressed Survivors of Breast Cancer

Childhood Cancer Survivors Who Received Nephrotoxic Therapy May Be at Greater Risk for Late Renal Problems

Myeloma Foundation Launches Open Access Gateways to Accelerate Drug Development

ASTRO: Younger Adults With a Limited Number of Brain Metastases Have Improved Overall Survival After Stereotactic Radiosurgery Alone

ASTRO: Proton Therapy Yields Encouraging Outcomes for Pediatric Brain Tumor Patients

USPSTF Issues Final Recommendation Statement on Medications for the Risk Reduction of Primary Breast Cancer in Women

HERA Trial Shows No Benefit of 2 Years vs 1 Year of Trastuzumab, Significant Survival Benefits of 1 Year vs Observation in Early Breast Cancer

ASTRO: Cisplatin Plus Radiation Therapy for Advanced Cervical Cancer Improves Disease-Free Survival vs Radiotherapy Alone

ASTRO: Long-Term Androgen Deprivation in Patients With Intermediate-Risk Prostate Cancer Does Not Improve Overall Survival

ASTRO: Fewer Weeks of Neoadjuvant Hormone Therapy Reduces Side Effects in Patients With Intermediate-Risk Prostate Cancer

Antiviral Treatment Improves Recurrence-Free and Overall Survival in HBV-Related Hepatocellular Carcinoma

NCCN: PET-Guided Therapy for Hodgkin Lymphoma Moving Into Clinical Practice

NCCN: Practical Considerations in Selecting Tyrosine Kinase Inhibitor Therapy for Chronic Myeloid Leukemia

Researchers Uncover Root Cause of Multiple Myeloma Relapse

Reduced Long-Term Survival and Increased Risk of Secondary Cancer in Younger Women After External Pelvic Radiation for Early-Stage Endometrial Cancer

Deficient DNA Mismatch Repair Associated With Favorable Prognosis in Proximal Tumors in Stage III Colon Cancer Patients Receiving Adjuvant FOLFOX

Scientists Find Possible Antidote for Tamoxifen-Induced Mental Fog

Japanese Study Shows Endoscopic Dual Tracer Method for Sentinel Node Mapping in Gastric Cancer Is Safe and Accurate

Widespread Contraindicated Use of Bevacizumab in Elderly Patients

MicroRNA Molecule Found to Be a Potent Tumor Suppressor in Lung Cancer

Meta-Analysis Suggests Fluorouracil or Gemcitabine Is Optimum Adjuvant Treatment for Pancreatic Cancer

Presence of RAS Mutations in Metastatic Colorectal Cancer Predictive of Negative Response to Panitumumab/FOLFOX4 Treatment

Statement by ASCO President Clifford A. Hudis, MD, FACP, in Support of the Rally for Medical Research Hill Day

Tremelimumab Shows Some Activity in Chemotherapy-Resistant Advanced Malignant Mesothelioma, Phase II Study Finds

Addition of Bevacizumab to Capecitabine Improves Progression-Free Survival in Elderly Patients with Previously Untreated Metastatic Colorectal Cancer

PDK1 Gene Identified as New Target for Melanoma Treatment

Young Breast Cancer Patients May Overestimate Benefit of Contralateral Prophylactic Mastectomy

AACR Issues 2013 Cancer Progress Report

Phase II Study Shows Durable Effect of Lenalidomide in Relapsed/Refractory Mantle Cell Lymphoma

New Plasma Biomarker Identified for the Diagnosis of Lung Cancer

Exploratory Analysis Suggests Response-Guided Neoadjuvant Therapy for Breast Cancer May Improve Survival

FDA Grants Volasertib Breakthrough Therapy Designation in Acute Myeloid Leukemia

FDA Grants Priority Review Designation for Dabrafenib/Trametinib Combination in Metastatic Melanoma

New Medical Device Treats Urinary Symptoms Related to Benign Prostatic Hyperplasia

FDA Grants Ofatumumab Breakthrough Therapy Designation for Previously Untreated CLL

FDA Approves First Generic Capecitabine to Treat Colorectal and Breast Cancers

Gene Expression–Based Biomarker Predicts Long-Term Risk of Breast Cancer Recurrence

Test Could Identify Which Prostate Cancers Require Treatment

Tivozanib Improves Progression-Free Survival but Not Overall Survival vs Sorafenib in Metastatic Renal Cell Carcinoma

Ipilimumab Fails to Significantly Prolong Survival in Patients With Advanced Prostate Cancer

Models Estimate Probability of Cancer in Pulmonary Nodules Detected on First Screening CT

ODAC Recommends Accelerated Approval of Pertuzumab for HER2-Positive, Early-Stage Breast Cancer

ASCO Issues Statement on National Childhood Obesity Awareness Month

Brachytherapy to Treat Cervical Cancer on the Decline in the United States

Dana-Farber Mourns the Passing of Jane Carrie Weeks, MD, MSc, National Leader in Outcomes Research

Versatile MicroRNAs Block Cancer Blood Supply, Suppress Metastasis

Modifiable Risk Factors Potentiate Therapy-Associated Risk for Major Cardiac Events in Adult Survivors of Childhood Cancer

Nonanthracycline Regimen Plus Trastuzumab Effective in Early Breast Cancer Irrespective of TOP2A Status

Breast Cancer Treatment in 10 Years: George Sledge, MD, Offers His Predictions

Low-Dose CT Screening Identifies More Early Lung Cancer But Has Lower Positive Predictive Value vs Radiography

Pomalidomide Plus Low-Dose Dexamethasone Improves Survival vs High-Dose Dexamethasone in Relapsed/Refractory Multiple Myeloma

FDA Grants Breakthrough Therapy Status to Entinostat for Advanced Breast Cancer

FDA Announces Class-Wide Safety Labeling Changes for Long-Acting Opioid Analgesics to Combat Abuse

NCI Scientists Use NanoString Technology to Identify Targets for Melanoma Immunotherapy

Researchers Uncover Genetic Cause of Childhood Acute Lymphoblastic Leukemia

FLT3 Inhibitor Quizartinib Shows Activity in Relapsed/Refractory AML

Dr. Larry Norton, Honored at 2013 Breast Cancer Symposium, Calls for Return to the ‘Exploration of Concepts’

Majority of Breast Cancer Deaths Occur in Younger, Unscreened Women, Study Finds

Low Adherence to Tamoxifen Therapy Increases Risk of Breast Cancer Recurrence and Early Death

Cabozantinib Improves Disease-Free Survival in Progressive Medullary Thyroid Cancer

Following Neoadjuvant Chemotherapy, Biomarkers Change in 41% of Breast Cancer Patients

Could MRI Be a Better Breast Cancer Screening Tool Than Mammography?

Molecular Marker Predicts Patients Most Likely to Benefit Longest From EGFR Inhibitors

Survival Advantage Seen in Glioblastoma Patients Taking Valganciclovir

FDA Approves Nab-Paclitaxel for Late-Stage Pancreatic Cancer

New Laser-Based Tool Could Dramatically Improve the Accuracy of Brain Tumor Surgery

Swallowing Exercises Preserve Function in Patients Receiving Radiation for Head and Neck Cancer

New Report Examines Trends in End-of-Life Care for Patients With Advanced Cancer

MRI Around the Time of Surgery Does Not Reduce Recurrence Rates in Women With DCIS

Large Study Shows That Radiation Therapy for DCIS May Not Increase Cardiovascular Disease Risk

Most Women Have an Inaccurate Perception of Their Breast Cancer Risk, Study Reveals

New Ultrasensitive Screening Method Can Detect Colon Cancer in Its Early Stages

Quality of Life Improves Over Time and Is Similar in Long-Term Breast Cancer Survivors and Women With No History of Breast Cancer

Survival Trend With Palliative FOLFOX4 vs Doxorubicin in Asian Patients With Advanced Hepatocellular Carcinoma

No Apparent Benefit of Adjuvant Gefitinib in Resected NSCLC in Prematurely Closed Trial

Germline Missense Mutations in BTNL2 Increase Susceptibility to Prostate Cancer

No Survival Benefit of Adjuvant Ibandronate in High-Risk Early Breast Cancer

First-Line Brivanib Not Noninferior to Sorafenib in Advanced Hepatocellular Carcinoma

No Overall Survival Benefit With Brivanib in Advanced Hepatocellular Carcinoma Patients After Sorafenib Failure or Intolerance

Danish Study Evaluates Risk of Mental Disorders in Siblings of Childhood Cancer Survivors

Study Compares Rituximab Maintenance to Observation After First-Line Treatment in Older Patients With Advanced Follicular Lymphoma

Scripps Florida Investigators Detail Critical Role of NOTCH1 Gene in Many Lung Cancer Cases

St. Jude's Study Yields New Strategy Against High-Risk Leukemia

School-Age Drinking Increases Breast Cancer Risk

High-Tech Imaging Contributes to Overdiagnosis, Overtreatment of Low-Risk Thyroid Cancers

ASCO Launches New Site to Seek Feedback From Cancer Community on Clinical Practice Guidelines

More Prudent Interpretation of Thyroid Ultrasound Could Reduce Unnecessary Biopsies

Vertebral Compression Fracture Risk Increased After Spinal Stereotactic Body Radiotherapy

Cord Blood Transplantation Benefits Some Children With Juvenile Myelomonocytic Leukemia

NCI Study Links Hodgkin Lymphoma Treatment to Risk of Stomach Cancer

Genomic Differences Found in Two Types of Cervical Cancer

Decreased White Matter Integrity and Neuropsychological Function Seen Decades After Cranial Radiotherapy for Pediatric Lymphoid Malignancies

Chinese Study Shows Icotinib Noninferior to Gefitinib in Advanced NSCLC

In International Study, Patients Prefer Subcutaneous Over Intravenous Trastuzumab for Breast Cancer

Preclinical Study Finds Tumor Suppressor May Actually Fuel Aggressive Acute Myeloid Leukemia

Single Injection of PV-10 Being Tested in the Treatment of Advanced Melanoma

African American Women Less Likely to Receive HPV Vaccine Than Whites, Study Finds

New Screening Strategy May Detect Ovarian Cancer at Early Stages

Sorafenib Granted Priority Review for Differentiated Thyroid Cancer

Dose-Dense Paclitaxel Plus Carboplatin Improves Long-Term Survival in Advanced Ovarian Cancer

Panobinostat Combined With Bortezomib and Dexamethasone Can Recapture Responses in Heavily Pretreated Patients With Multiple Myeloma

Many Patients With Head and Neck Cancer Report Being Depressed, But Few Use Mental Health Services

Low Risk of Transformation to Melanoma for Biopsy-Diagnosed Mildly or Moderately Dysplastic Nevi, So Surgical Excision May Not Be Indicated

Task Force Recommends Interventions to Prevent Tobacco Use in Children

FDA Approves Mechlorethamine Gel for Cutaneous T-Cell Lymphoma

Survival Advantage Seen in Foreign-Born Hispanics With NSCLC

Meta-Analysis Indicates BEACOPPescalated Is Superior in Advanced Hodgkin Lymphoma

Indoor Tanning Common Among Young White Females Despite Skin Cancer Risk

Yoga Improves Sleep Quality in Cancer Patients With Sleep Disruption

Cost-Effectiveness of MRI Screening for Women With Familial Risk of Breast Cancer in the Netherlands

Smoking Cessation and Prevention App Free on iTunes

Enhanced Treatment, Surveillance Needed for Certain Melanoma Patients to Prevent Secondary Cancers, Researchers Say

Risk of Pancreatic Cancer May Be Reduced by Better Diet

Brain Cancer Survival Improved Following FDA Approval of Bevacizumab, Mayo Study Finds

Preclinical Tests May Lead to New Approach to Treat CNS Lymphoma

Researchers Identify Key Protein in Treatment-Resistant Prostate Cancer

NSABP B-38 Trial Shows No Benefit of Adding Fourth Drug to Standard Adjuvant Treatment in Women With Node-Positive Breast Cancer

Night or Rotating Shift Work Associated With Increased Risk for High PSA

Study Determines Optimal Chemotherapy Regimen for Younger Patients With AML

New Research Suggests Restricting Calories May Improve Response to Cancer Treatment

Poor Oral Health Is an Independent Risk Factor for Cancer-Causing Oral HPV Infection

Best of ASCO 2013: VeriStrat Assay May Help Select NSCLC Patients for Second-Line Therapy

No Progression-Free Survival Difference for Cediranib or Cediranib/Lomustine vs Lomustine in Recurrent Glioblastoma

Similar 10-Year Survival in Patients With Early-Onset BRCA1-Negative and BRCA1-Positive Breast Cancer

Multicenter Trial Finds BI-RADS 3 Breast Lesions Have Low Cancer Rate

Gene That Helps Control Aging Is Linked to Multiple Myeloma

New MRI Technique Reveals Brain Tumor Response to Antiangiogenesis Therapy

Risk-Directed Treatment Intensification Significantly Improves Outcomes in Children With ALL and Intrachromosomal Amplification of Chromosome 21

Intrachromosomal Amplification of Chromosome 21 Associated With Poor Outcome in Children With ALL

Neoadjuvant Carboplatin Before Radiotherapy May Reduce Risk of Relapse and Long-Term Side Effects in Men With Testicular Cancer

Tumor Measurements Predict Survival in Advanced Non–Small Cell Lung Cancer

Finasteride Reduces Risk of Low-Grade Prostate Cancer With No Impact on Long-Term Survival

Best of ASCO 2013: Promises and Challenges of Applying Molecular Profiling to Clinical Practice

No Invasive Disease-Free Survival Benefit of Adding Bevacizumab to Adjuvant Chemotherapy in Triple-Negative Breast Cancer

Study Finds 1 in 5 Women Don’t Believe Their Breast Cancer Risk

Breastfeeding for More Than 6 Months May Protect Against Breast Cancer in Nonsmoking Women

‘Reprogrammed’ Treatment-Resistant Lymphomas Respond to Azacitidine

Addition of Sunitinib to Capecitabine Does Not Improve Outcome in Previously Treated Metastatic Breast Cancer

Cancer Incidence Trends in Asian American Populations Indicate Need for Increased Prevention and Surveillance

Best of ASCO 2013: Off-Label Prescribing of Chemotherapy Drugs Is Common but Most Meets NCCN Compendium Criteria

Age-Related Variations Observed in Treatment of Melanoma

Researchers Identify Key Mechanism Behind Castration-Resistant Prostate Cancer

Enhanced Treatment, Surveillance Needed for Patients With BRAF-Mutant Melanoma to Prevent Secondary Cancers

New Study Supports Role of Epithelial-to-Mesenchymal Transition in Patients With Ovarian Cancer

Combined Microsatellite Instability and BRAF Status a Potential Marker of Risk Stratification in Colorectal Cancer

Study Suggests Low-Grade Prostate Cancers May Not Progress Over Time

Study Suggests Neural Stem Cells May Regenerate After Radiation Therapy

Family Members of Children With Cancer Are Also at Risk for the Disease

Meta-Analysis Indicates Addition of Taxane to Cisplatin/5-FU Induction Improves Outcome in Locally Advanced Head and Neck Cancers

Circulating Estrogens and Androgens Are Associated With Breast Cancer Risk in Premenopausal Women

FDA Approves Dolutegravir to Treat HIV-1 Infection

Study Identifies Interleukin-11 as a Potential New Anticancer Target

Certain Major Birth Defects Associated With Moderately Increased Cancer Risk in Children

Carbon Ion Radiotherapy Safe and Effective for Treating Inoperable Spinal Tumors

Cohort Analysis Shows Adjuvant Tamoxifen Reduces Risk of Contralateral Breast Cancer in BRCA1 and BRCA2 Mutation Carriers

Lab-Grown Stem Cell–Derived T Cells Fight Cancer in Tumor-Bearing Mice

Researchers Identify Gene Variations in Lung Cancer Patients That May Help Predict an Individual’s Treatment Response

Burkitt Lymphoma Survival Outcomes Improve for Younger Patients

NIH Scientists Visualize How Cancer Chromosome Abnormalities Form in Living Cells

No Benefit/Detriment of New Donor in Second Hematopoietic Stem Cell Transplantation for Leukemia Relapse

Whole-Genome Sequencing Reveals Mutation Signature in Aristolochic Acid–Associated Upper Urinary Tract Cancer

FDA Approves First Rapid Diagnostic Test to Detect Both HIV-1 Antigen and HIV-1/2 Antibodies

Study Suggests Pattern in Lung Cancer Pathology May Predict Cancer Recurrence After Surgery

Biomarker May Predict Risk of Graft-vs-Host Disease After Stem Cell Transplant

Study Analyzes Oncologists’ Attitudes Regarding Patient-Reported Outcomes

FDA Grants Orphan Drug Status to Eisai’s Investigational Compound E7777 for Cutaneous T-Cell Lymphoma

Tositumomab/Iodine-131 Tositumomab Regimen for Non-Hodgkin Lymphoma to Be Discontinued

Loss of MicroRNA Decoy Might Contribute to Development of Soft-Tissue Sarcoma

Metformin Use Reduces All-Cause and Prostate Cancer–Specific Mortality in Men With Diabetes

Researchers Identify Origin of Inflammation-Driven Pancreatic Cancer

Dabrafenib Active in BRAF-600E/K Mutant Metastatic Melanoma

Vaccine Stirs Immune Activity Against Advanced Chronic Lymphocytic Leukemia

Risk for Lymphoma Increases in Celiac Patients With Persistent Villous Atrophy

Noninvasive Test Optimizes Colon Cancer Screening Rates

Percentage of Cancers Linked to Viruses Potentially Overestimated

Study Reveals Genes That Drive Glioblastoma

Long-Term Calcium-Channel Blocker Use for Hypertension Associated With Higher Breast Cancer Risk

Sanford-Burnham Researchers Map a New Metabolic Pathway Involved in Cell Growth

Mechanism Offers Promising New Approach for Harnessing the Immune System to Fight Cancer

No Difference in Outcome With Purged vs Nonpurged Peripheral Blood Stem Cell Transplantation in High-Risk Neuroblastoma

Experts Discuss Challenges in Counseling Patients About Contralateral Prophylactic Mastectomy

Researchers Target ‘Cell Sleep’ to Lower Chances of Cancer Recurrence

No Additional Benefit of Double Endocrine Treatment After Progression on Aromatase Inhibitors in Advanced Hormone Receptor–Positive Breast Cancer

Omega-3 Fatty Acids May Aid in Treatment and Prevention of Skin and Oral Cancers

FDA Warns of Rare but Serious Skin Reactions with Acetaminophen

PET/CT Superior to Bone Marrow Biopsy for Diagnosis and Prognosis of Lymphoma Patients

Lenalidomide plus Dexamethasone Delays Progression and Improves Survival in High-risk Smoldering Multiple Myeloma

Targeted Therapy Identified for Protein that Protects and Nourishes Cancer

Blocking Sugar Intake May Reduce Cancer Risk or Progression in Certain Malignant Tumors

Researchers Uncover How a Potent Compound Kills Prostate Cancer Cells

Benefit Seen with Both Autologous and Allogeneic Hematopoietic Cell Transplantation in T-cell Non-Hodgkin Lymphoma

Nonsentinel Lymph Node Positivity Appears to be Significant Prognostic Factor in Patients with Melanoma

Acute Myeloid Leukemia Induces Bone Marrow Failure by Inhibiting Production of Hematopoietic Stem Cells

Digital Breast Tomosynthesis Reduces Breast Cancer Screening Recall Rate Compared to Mammography Alone

Some Women with Abnormal Breast Lesions May Avoid Surgery

Researchers Find Link Between Intestinal Bacteria and Lymphoma

Decision Aids Reduce Men's Conflict about PSA Screening, but Don't Change Their Decisions

James L. Mulshine, MD, Comments on U.S. Preventive Services Task Force Recommendations for CT Screening for Lung Cancer in High-risk Individuals

U.S. Preventive Services Task Force Recommends Screening for Lung Cancer in High-risk Individuals

Low-dose CT Screening for Lung Cancer: Details of First Round of Screening in National Lung Screening Trial

NCI Working Group Recommends Changes to Screenings, Treatments, and the Definition of Cancer

Swedish Initiative Results in Significant Reduction in Inappropriate Prostate Cancer Imaging

Higher Incidence of Non-Hodgkin Lymphoma Found in Regions with Close Proximity to Benzene Release Sites

Gene Test Highly Accurate in Predicting Metastasis in Patients with Thymoma

Richard I. Fisher, MD, Named President and CEO of Fox Chase Cancer Center

Particulate Matter Air Pollution Contributes to Increased Risk of Lung Cancer in Europe

No Benefit of Adding Atrasentan to Docetaxel in Advanced Castration-resistant Prostate Cancer

Intratumoral IL-12 Injections Shrink Melanoma and Merkel Cell Tumors

CDC Report Shows Stagnated HPV Vaccination Rate for Girls

FDA Limits Usage of Oral Ketoconazole Due to Potentially Fatal Liver Damage

Docetaxel Superior to Erlotinib in Second-line Treatment of Advanced NSCLC with Wild-type EGFR

Large Study Reveals Increased Cancer Risks Associated with Family History of the Disease

New Biomarker for Colorectal Cancer Could Help Predict Whether Disease Will Spread

Height Significantly Linked to Cancer Risk in Postmenopausal Women

Digital PCR Technology Detects Brain Tumor–associated Mutation in Cerebrospinal Fluid

AACR Warns That Diminished NIH Funding Jeopardizes Ability to Eradicate Cancer Health Disparities

FDA Invites Public Input on Menthol in Cigarettes

Study Evaluates Therapeutic Impact of Laparoscopic Para-aortic Staging Surgery before Chemoradiotherapy in Cervical Cancer

No Difference in Event-free Survival with Chemotherapy before vs after Radiation Therapy in Children with High-risk Medulloblastoma

Difference in Breast Cancer Survival Between Black and White Women Has Not Changed Substantially

Oxygen Decelerates Many Tumors When Combined with Radiation Therapy

Study Finds Boys More Likely to Receive HPV Vaccine When Their Mothers Receive Preventive Care

Molecular Profiling Improves Classification of Nodal Peripheral T-cell Lymphomas

Study Reveals Best of Three Schedules of Nab-paclitaxel/Bevacizumab in Metastatic Breast Cancer

National Lung Screening Trial Analysis Supports Risk-based Targeting of Smokers for Low-dose CT Screening

Integrative Medicine Interventions Found to Significantly Reduce Pain, Improve Quality of Life

Protein Complex Linked to Cancer Growth May Act as Tumor Suppressor

Radium-223 Dichloride Prolongs Overall Survival in Men with Metastatic Prostate Cancer in Phase III ALSYMPCA Trial

Female Survivors of Childhood Cancer Have Increased Risk of Infertility

Adenovirus-mediated Gene Therapy with Sitimagene Ceradenovec Prolongs Median Time to Death or Reintervention in Adult Glioblastoma

Cancer Survivors Have More Frequent and Severe Menopausal Hot Flashes

Progesterone and Estrogen Receptor Expression Are Prognostic Markers for Endometrioid and High-grade Serous Ovarian Cancer

Study Suggests Proteins Involved in Immunity May Be Responsible for Cancer-causing Mutations

HPV Vaccine Reduces Prevalence of Oral HPV Infections in Costa Rican Study

Cancer Survivors Might Have a Decreased Risk for Alzheimer's Disease

Alternate-day, Low-dose Aspirin May Reduce Colon Cancer Risk

American Ginseng Improves Cancer-related Fatigue

Accelerated Partial-breast Irradiation Using 3D Conformal Radiation Therapy Causes More Adverse Events Compared with Whole-breast Irradiation

Molecular Relative of p53 Tumor-suppressor Protein also Helps Cancer Cells Thrive

Cancer Patients with Cardiovascular Risk Factors Who Receive Chest Radiation Should Have Cardiovascular Screening Every 5 to 10 Years

Bevacizumab/Pemetrexed Maintenance Increases Progression-free Survival vs Bevacizumab Alone in Advanced Nonsquamous NSCLC

Cancer Organizations Provide Support for Required Cancer Center Distress Screening Programs

Use of Androgen Deprivation Therapy for Treatment of Prostate Cancer Associated with Increased Risk of Acute Kidney Injury

Most Commonly Used Ovarian Cancer Cell Lines Do Not Resemble Ovarian Cancer

Significant Improvement in Overall Survival Seen with Pemetrexed Maintenance after Pemetrexed/Cisplatin Induction in Patients with Advanced NSCLC

Obinutuzumab Shows Activity in Relapsed/Refractory Diffuse Large B-cell Lymphoma or Mantle Cell Lymphoma and Indolent Non-Hodgkin Lymphoma

Colorectal Cancer Survivors Face Increased Risk of Developing Subsequent Cancers of Different Types

Anxiety Is a Long-term Problem for Cancer Survivors and Spouses

Whole-exome Sequencing of the NCI-60 Cell Line Panel Provides a Genomic Resource for Cancer Biology and Systems Pharmacology

Nerves Play Key Role in Triggering Prostate Cancer and Promoting Metastases

Predicting Risk of Treatment-related Mortality in Advanced-stage Hodgkin Lymphoma

Revised International Prognostic Scoring System for MDS Is Better at Predicting Survival than Older Systems

Nomogram Accurately Predicts Salivary Gland Cancer Recurrence

FDA Approves Afatinib for EGFR-mutant Late-stage Non–Small Cell Lung Cancer

Jamie H. Von Roenn, MD, Joins ASCO as Head of Education, Science, and Professional Development

Protein Targeted for Cancer Drug Development Is Essential for Normal Heart Function

Study Confirms Link Between High Blood Levels of Omega-3 Fatty Acids and Increased Risk of Aggressive Prostate Cancer

Critical Pathway in Cell Cycle May Lead to Cancer Development

Addition of Aflibercept to Docetaxel/Prednisone Does Not Improve Overall Survival in Men with Metastatic Castration-resistant Prostate Cancer

Addition of Panitumumab to Cisplatin/Fluorouracil Improves Progression-free Survival in Patients with Recurrent or Metastatic Head and Neck Cancer

Targeting Errant Immune System Enzyme Kills Myelodysplastic Cells

Factors Influencing Delay in Breast Cancer Treatment Differ for African American and White Women

Targeted Genetic Dependency Screen Identifies New Treatment Targets for Lung Cancer

Infertility in Men Raises Their Risk for Cancer

Aspirin May Help Prevent Cancer in Patients with Barrett’s Esophagus

New Guidelines Issued in the Treatment of Multiple Myeloma–related Bone Disease

New Drug Application Submitted for Ibrutinib in the Treatment of Two B-cell Malignancies

Soy Protein Supplementation Does Not Reduce Risk of Prostate Cancer Recurrence after Radical Prostatectomy

Technologies for Monitoring Minimal Residual Disease May Help Predict Outcomes for Patients with Leukemia

Nearly Half of Sarcoma Surgeries Performed by Nononcologists

Afatinib Prolongs Progression-free Survival Compared with Cisplatin plus Pemetrexed in EGFR-mutant Advanced Lung Adenocarcinoma

Bladder-sparing Trimodal Chemotherapy Produces Good Response in Patients with Muscle-invasive Bladder Cancer

High Prediagnosis Red Meat Consumption Associated with Increased All-cause Mortality in Patients with Colorectal Cancer

Proton Radiation Is Not Associated with Increased Risk of Secondary Cancers When Compared with Photon Radiation

ASCO Releases Updated Guideline on Interventions for Women at Increased Risk for Breast Cancer

Five-year Survival Data from the Phase III CLASSIC Trial Show a 34% Reduction in Gastric Cancer Mortality

Two HIV Patients Show No Signs of Disease Following Bone Marrow Transplants for Hodgkin Lymphoma

Volumetric Growth Rate of Small Colorectal Polyps on CT Colonography May Be Useful Risk Marker

African Americans with Chronic Lymphocytic Leukemia Do Not Live as Long as Caucasians, Despite Equal Care

ASCO and Other Cancer Groups Ask for Guidance on Protecting Patient Access to Clinical Trials

Height Differences May Explain Excess Cancer Risk for Men

Single Men, Smokers at Higher Risk for Oral HPV Infection

FDA Grants Priority Review to Obinutuzumab in CLL and Pertuzumab in Neoadjuvant Therapy for HER2-positive Early-stage Breast Cancer

Novel Drug Combination Shows Activity in Recurrent Ovarian Cancer

L1CAM Predicts Recurrence and Poor Outcome in Early-stage Type I Endometrial Cancer

Increasing Incidence of Papillary Thyroid Cancer Linked to Overdiagnosis

Scientists Develop Mathematical Model to Predict Cancer Cells’ Resistance to Therapy

Stereotactic Body Radiation Therapy Safe and Effective for Patients with Stage I Non–Small Cell Lung Cancer

Intercalated Chemotherapy plus Erlotinib Improves Survival in Asian Patients with Advanced NSCLC and Known or Unknown EGFR Mutation Status

Novel Research Method May Lead to Tailored Treatments for Late-stage Prostate Cancer

WHO Tobacco Control Policies Estimated to Prevent 7.4 Million Premature Deaths by 2050

Biomarker Predicts Risk of Breast Cancer Recurrence after Tamoxifen Treatment

Oral Apixaban Lowers Rates of Major Bleeding in Patients with Acute Venous Thromboembolism

Acupuncture May Reduce Arm Lymphedema in Patients with Breast Cancer

Progression of Renal Cell Carcinoma Linked to Shifts in Tumor Metabolism

Surgeons Report Melanoma Recurs after 10 Years in More than 6% of Patients

Crizotinib Improves Progression-free Survival vs Pemetrexed or Docetaxel in Advanced ALK-positive NSCLC

Survival Rates for Patients with Burkitt’s Lymphoma Improve, Especially among Young Adults

Active Surveillance May Miss Aggressive Prostate Cancers in African American Men

Study Sets Guidelines for Stem Cell Transplants in Older Patients with Myelodysplastic Syndromes

Among White Adolescents and Young Adults with Melanoma, Males Have Higher Mortality Than Females

Lugano 2013: BCL2 Overexpression and Non–Germinal Center B-cell–like Subtype Predict Poorer Survival in Diffuse Large B-cell Lymphoma

Majority of Patients with Incurable Lung Cancer Have Inaccurate Expectations about Goals of Radiation Therapy

Study Reveals Abstracts with Financial Conflicts of Interest Have Higher Meeting Prominence, Better Peer Review Score

Lugano 2013: Vitamin D Deficiency Associated with Worse Outcome in Elderly Patients with Aggressive B-cell Lymphoma Receiving R-CHOP or CHOP

Lugano 2013: Chlorambucil plus Rituximab Produces Better Event-free and Progression-free Survival in Extranodal Marginal Zone B-cell Lymphoma

Study Shows Isoflavone Exposure Has Little Effect on Breast Cancer Risk or Recurrence

BRAF Mutation Status May Have Effect on Benefit of Aspirin Use for Patients with Colorectal Cancer

Use of Advanced Treatment Technologies Increases among Men at Low Risk of Dying from Prostate Cancer

Lugano 2013: PET-guided Radiation Therapy Improves Survival in Patients with Advanced Diffuse Large B-cell Lymphoma

Lugano 2013: Ibrutinib Highly Active in Patients with Chronic Lymphocytic Leukemia with 17p Deletion

New Study Finds AICR Recommendations Cut Breast Cancer Risk

Chemotherapy-induced Neuropathy Has Long-term Effect on Colorectal Cancer Survivors

BTK Inhibitor Ibrutinib Produces High Response Rate in Relapsed/Refractory Mantle Cell Lymphoma

Two Bills before Congress Aim to Fight Breast Cancer and End Disparities in Care

High Rate of Durable Remissions with BTK Inhibitor Ibrutinib in Patients with Relapsed Chronic Lymphocytic Leukemia

Researchers Identify and Map Signaling Pathway from EGFR to MCM7 Protein

Investigators Identify Promising Biomarker for Predicting HPV-related Oropharyngeal Cancer

Deep Sequencing Accurately Predicts Prolonged Survival in Multiple Myeloma Patients

Follicular Lymphoma Cells Induce Changes in T-cell Gene Expression and Function, Show Prognostic Significance for Survival

Study Shows HPV Vaccine Reduced Rate of Infection in Teenage Girls by 56%

Virus Combination Effective Against Temozolomide-resistant Glioblastoma Multiforme

First-line Carboplatin plus Pemetrexed Improves Survival vs Pemetrexed Alone in Patients with Advanced NSCLC and Poor Performance Status

Observation Is Safe, Cost-saving Option for Patients with Low-risk Prostate Cancer

Screening Colonoscopy Associated with Increased Survival Duration and Rates for Patients with Colon Cancer

Mortality Appears to be Higher for Patients with Thicker Single Primary Melanomas than for Thicker Multiple Primary Melanomas

Investigational New Drug Application Filed for CFI-400945

Imatinib Active in Melanomas with KIT Mutation but Not KIT Amplification Alone

Novel Selective ALK Inhibitor Demonstrates Good Activity in Advanced NSCLC

Global Alliance Is Formed to Share Genomic Data

PHARE Trial Fails to Establish Noninferiority of 6 vs 12 Months of Adjuvant Trastuzumab in Early HER2-positive Breast Cancer

Impact of Age on Efficacy of Newer Adjuvant Therapies in Patients with Stage II/III Colon Cancer

Acetyl-L-carnitine Ineffective for Taxane-related Peripheral Neuropathy

ASCO 2013: Genomic Heterogeneity Can Lead to the Selection of ‘Incorrect’ Targeted Inhibitors

Accountable Care Organizations May Be at Risk for New Medical Liabilities

NCI Will No Longer Accept R01 and P01 Applications for Phase III Clinical Trials of Medical Interventions and Cancer Imaging Modalities

FDA Approves New Silicone Gel-filled Breast Implant

Abnormalities in New Molecular Pathway May Increase Breast Cancer Risk

Osteoporosis Drug Stops Growth of Breast Cancer Cells in Tamoxifen-resistant Tumors

Metabolic Molecule Drives Growth of High-grade Glioma

Developmental Protein Plays Role in Spread of Cancer

Trebananib plus Paclitaxel Significantly Delays Disease Progression in Patients with Recurrent Ovarian Cancer

Human Genes May Not Be Patented, Rules the Supreme Court

Younger Age Does Not Significantly Impact Recurrence or Benefit from Trastuzumab in Early-stage HER2-positive Breast Cancer

FDA Approves Denosumab to Treat Giant Cell Tumor of the Bone

Newly Identified Markers May Predict Who Will Respond to Breast Cancer Prevention Therapy

ASCO 2013: First Prospective Trial Shows Molecular Profiling Timely for Tailoring Therapy

ASCO 2013: Lung Cancer Mutations ALK and ROS1 Also Drive Colorectal Cancer

Research Team Identifies Genetic Risk for Cancer in Breast Cells

Critically Ill Patients with Hematologic Malignancies Admitted to ICU Have Good Survival, Disease Control, and Quality of Life

ASCO 2013: Top Five Things Oncologists Need to Know about Cancer in Older Adults

CMS Says It Lacks Authority to Roll Back Sequestration Cuts to Medicare Payments for Part B Cancer Drugs

Radioimmunotherapy/Chemotherapy Combination Could Extend Survival in Some Patients with Advanced Lymphoma

Study Paves Way for Rational Drug Targeting of B-cell Lymphomas

Sequential PET/MRI Predicts Chemotherapy’s Ability to Improve Survival in Patients with Advanced Breast Cancer

Reducing Unnecessary and High-dose Pediatric CT Scans Could Cut Future Cancers by More than Half

National Institutes of Health Issues Projected Impact of Sequestration on Programs

ASCO 2013: Surveillance Sufficient Follow-up for Most Patients with Stage I Seminoma

Some Stage II/III HER2-positive Tumors May Be Treated with Targeted Therapy without Chemotherapy

FDA Grants Orphan Drug Status for Novel Targeted Therapy for the Treatment of Rare Hematologic Cancer

ASCO 2013: Novel Heat Shock Protein Inhibitor Effective in Combination with Docetaxel as Second-line Therapy for Advanced Lung Cancer

FDA Clears Multicenter Trial of Treatment for Chemotherapy-related Hair Loss

ASCO 2013: More than 20% of African American Women Carry Inherited Mutations in at Least One Breast Cancer Susceptibility Gene

ASCO 2013: Less Lymphedema with Axillary Radiotherapy than Node Dissection, but Comparable Disease Control

ASCO 2013: Adapting to Ongoing Shortages of Common Cancer Drugs

Potential New Way to Suppress Tumor Growth Discovered

Clinical Sequencing Technology Identifies New Targets in Diverse Cancers

ASCO 2013: Weekly Paclitaxel Is Less Toxic but as Effective for Women with Higher-risk Early-stage Breast Cancer

DNA Sequencing Reveals Mucosal Melanoma's Genetic Fingerprint

ASCO 2013: Adding Bevacizumab to Standard First-line Chemoradiation for Glioblastoma Does Not Improve Overall Survival

PTEN Variant Demonstrates Tumor Suppressor and Regression Activity in Human and Animal Tissue

ASCO President Clifford Hudis, MD, on the 2013 ASCO Annual Meeting

Cytomegalovirus Might Speed Brain Cancer Growth

ASCO 2013: Cervical Cancer Screening Using Visual Inspection with Vinegar Reduces Mortality by 31% in Large Study in India

ASCO 2013: 10 Years of Tamoxifen Better Than 5 in Reducing Breast Cancer Recurrence and Death

ASCO 2013: Sorafenib Stalls Growth of Treatment-resistant Differentiated Thyroid Cancer

FDA Approves Lenalidomide for Patients with Relapsed or Refractory Mantle Cell Lymphoma

ASCO 2013: No Increased Risk of Oral HPV Infections Reported in Long-term Partners of Patients with HPV-positive Oropharyngeal Cancers

In the Clinic: Trametinib in Unresectable or Metastatic Melanoma with BRAF V600E or BRAF V600K Mutation

ASCO 2013: Cetuximab Offers Survival Advantage over Bevacizumab When Combined with FOLFIRI for First-line Treatment of Advanced Colorectal Cancer

ASCO 2013: Adding Bevacizumab to Chemotherapy Significantly Improves Response Rates and Survival in Women with Advanced Cervical Cancer

ASCO 2013: Nivolumab Produces Durable Responses in Patients with Stage IV Melanoma

ASCO 2013: Selumetinib Significantly Improves Progression-free Survival for Patients with Advanced Melanoma of the Eye

FDA Grants Fast Track Designation to SGX942 for the Treatment of Oral Mucositis

ASCO 2013: Adding GM-CSF to Ipilimumab Significantly Improves Survival for Patients with Metastatic Melanoma

ASCO 2013: Pazopanib Maintenance Therapy Delays Relapse of Advanced Ovarian Cancer

ASCO 2013: Anti–PD-1 Antibody Produces Durable, Ongoing Response in Patients with Advanced Melanoma

ASCO 2013: Most U.S. Oncologists Report High Career Satisfaction, but Many Suffer Symptoms of Burnout

ASCO 2013: Everolimus Significantly Delays Tumor Growth in Women with HER2-positive Advanced Breast Cancer

Experts Call for Breast Cancer Trials Aimed at Younger Patients

New Method to Test Breast Lesions Could Better Detect Cancer and Reduce Repeat Biopsies

ASCO 2013: For Patients with Metastatic Pancreatic Cancer, Both Treatment and Survival Decrease with Advanced Age

New Possibilities for Prostate Cancer Treatment

Ofatumumab plus Chlorambucil Improves Progression-free Survival in Patients with Previously Untreated CLL

FDA Approves Two Drugs, Companion Diagnostic Test for Advanced Skin Cancer

Frequent Heartburn May Predict Cancers of the Throat and Vocal Cord

Researchers Identify Novel Class of Drugs for Prostate Cancers

New Research Shows Significant Improvement in Overall Survival Outcomes for Patients Receiving Blood Stem Cell Transplants

Breaking News on Lymphoma and Myeloma to Be Reported at European Hematology Congress in Stockholm

EGFR Prevents Maturation of Cancer-fighting microRNAs under Hypoxia

Mayo Clinic Genomic Analysis Lends Insight to Prostate Cancer

Intensified Liposomal Daunorubicin May Offer High Survival Rates without Added Cardiotoxicity for Children with Leukemia

Phase II Trial Targeting Genetic Anomaly in Castration-resistant Metastatic Prostate Cancer Underway

Low-dose CT Detects Twice as Many Early-stage Lung Cancers as Chest X-ray, According to Additional NLST Results

Inflammatory Bowel Disease Raises Risk of Melanoma

Beta-blockers May Boost Chemotherapy Response in Neuroblastoma

Genetic Diversity Predicts Outcomes in Head and Neck Cancer

Study: Gold Nanoparticles Can Help Fight Ovarian Cancer

FDA Approves Low-dose, Two-dimensional Mammography Software

Molecular Marker from Pancreatic 'Juices' Helps Identify Pancreatic Cancer

ASCO 2013: Routine Surveillance Imaging Scans Add Little to Detection of Relapse in Patients with Diffuse Large B-cell Lymphoma

ASCO 2013: Surveillance Following Surgery Is Sufficient for Men with Stage I Seminoma

ASCO 2013: New Drug Targeting PI3K-delta Shows Strong Activity in Early Trial for High-risk Chronic Lymphocytic Leukemia

ASCO 2013: PARP Inhibitor Shows Activity in Pancreatic, Prostate Cancers among Patients Carrying BRCA Mutations

ASCO 2013: Standard-dose Radiation Is Superior to High-dose Radiation for Patients with Locally Advanced Stage III NSCLC Undergoing Chemotherapy

ASCO 2013: Phase I Trial Suggests Ipilimumab and PD-1 Drug Nivolumab May Be Better Together than Alone for Advanced Melanoma

ASCO 2013: Men’s Fitness in Middle Age Protects against Developing and Dying from Cancer Later in Life

ASCO 2013: Anti–PD-L1 Drug Shows Promising Anticancer Effects in a Variety of Advanced Cancers

Study Identifies Possible New Treatment Target for Acute Leukemia

FDA Approves Radium-223 Dichloride for Patients with Castration-resistent Prostate Cancer

FDA Approves Expanded Use for Erlotinib, Companion Diagnostic to Detect Genetic Mutations in NSCLC

Study: Popular Diabetes Drug Does Not Improve Survival Rates after Cancer

Dual Targeting of Metastatic Breast Cancer Improves Survival Rates

Study Establishes Basis for Genomic Classification of Endometrial Cancers

Blocking a Single Gene Renders Tumors Less Aggressive, Johns Hopkins Researchers Find

Bladder Cancer Could Recur despite Bladder Removal

FDA Warns about Potential Medication Errors Resulting from Confusion Regarding Nonproprietary Name for Kadcyla (ado-trastuzumab emtansine)

Emil ‘Tom’ Frei III, MD, Trailblazer in the Development of Combination Chemotherapy, Dies at 89

Experimental Drug Beneficial in NIH Trial to Treat a Rare Sarcoma

Radiation Therapy May Be Unnecessary for Postmenopausal Patients with Early-stage Breast Cancer after Conservative Surgery

Daratumumab Receives Breakthrough Therapy Designation in Multiple Myeloma

Women Smokers May Have Greater Risk for Colon Cancer Than Men

Selective Estrogen Receptor Modulators Reduce Breast Cancer Rates by More Than a Third in Women at High Risk

Congress Must Reverse Devastating Budget Cuts to Cancer Care

Researchers Identify New Pathway, Enhancing Tamoxifen to Tame Aggressive Breast Cancer

Obese Men with Benign Biopsy at High Risk for Prostate Cancer

Delays in Diagnosis Worsen Outlook for Minority, Uninsured Pediatric Retinoblastoma Patients, Study Finds

Researchers Observe an Increased Risk of Cancer in People with History of Nonmelanoma Skin Cancer

Majority of Children Readmitted to Hospital Following Stem Cell Transplant

Breakthrough Therapy Designation for Lambrolizumab for the Treatment of Advanced Melanoma

Chernobyl Follow-up Study Finds High Survival Rate among Young Thyroid Cancer Patients

Bipartisan Group of 124 Lawmakers Express Concern That Medicare Cuts to Life-sustaining Cancer Drugs Threaten Patient Care

New Agent Might Control Breast Cancer Growth and Spread

Study to Treat Deadly Form of Thyroid Cancer Shows Promise, Mayo Clinic Says

Pharmacyclics Completes Enrollment of Phase III Ibrutinib CLL Study and Phase II Ibrutinib MCL Study

Few Breast Cancer Survivors Maintain Adequate Physical Activity Despite Benefits

New Labeling for Reformulated OxyContin to Curb Abuse

The U.S. Supreme Court Hears Arguments Challenging Patents on Breast and Ovarian Cancer Genes

Some Minorities Believe They Are Less Likely to Get Cancer Compared to Whites, Moffitt Cancer Center Study Shows

Cryoablation Spot Treats Cancer in the Lung, Extends Survival

Mammogram Tool Improves Some Breast Cancer Detection but Also Increases False Alarms

Key Bone Marrow Protein Identified as Potential New Leukemia Treatment Target

Asbestos Exposure, Asbestosis, and Smoking Combined Greatly Increase Lung Cancer Risk

NIH Trial Shows Promising Results in Treating Primary Mediastinal B-cell Lymphoma

Joint Statement on the President's Budget from ASCO, Community Oncology Alliance, ION Solutions, and the US Oncology Network

Novel Drug Combination Showed Antitumor Activity in Patients with Incurable BRCA-deficient Cancers

Adding Cetuximab to Chemotherapy Enables Select Patients with Advanced Colorectal Cancer and Liver Metastasis to Undergo Surgery

Alcohol Consumption Has No Impact on Breast Cancer Survival, According to New Research

Black Women Had Worse Breast Cancer Mortality Regardless of Cancer Subtype

Immunotherapy Showed Promising Antileukemia Activity in Pediatric Patients

Novel Two-step Immunotherapy Showed Promise for Patients with Recurrent Ovarian Cancer

Biomarker Analysis Identified Women Most Likely to Benefit from T-DM1

Statement by ASCO President Sandra M. Swain, MD, FACP, in Support of the Rally for Medical Research, April 8, 2013

Ibrutinib Receives Third Breakthrough Therapy Designation from the FDA

New Type of Experimental Drug Active in Platinum-resistant Ovarian Cancers

Leading Health-care Organizations Issue Guideline Recommendations for Molecular Testing and Targeted Therapies

New Minimally Invasive, MRI-guided Laser Treatment for Glioblastoma Found to Be Promising in Study

For the First Time, Researchers Isolate Adult Stem Cells from Human Intestinal Tissue

On-and-off Approach to Prostate Cancer Treatment May Compromise Survival

Antidepressant Helps Relieve Pain from Chemotherapy, Study Finds

New Diagnostic Technology May Lead to Individualized Treatments for Prostate Cancer

National Cancer Organizations Issue Joint Statement on Devastating Impact of Sequestration

Cisplatin-resistant Cancer Cells Sensitive to PARP Inhibitors

New Drug Target, Companion Prognostic Test for Hormone Therapy–resistant Breast Cancer

Roswell Park Scientists Advance Findings about Novel, Low-toxicity Anticancer Agent

Prostate Cancer Risk Rises in Men with Lynch Syndrome

Mayo Clinic: New DNA Sequences Hone in on Breast, Ovarian Cancer Risk

New Metabolite-based Diagnostic Test Could Help Detect Pancreatic Cancer Early

Many Doctors Do Not Provide Tobacco Cessation Assistance to Lung Cancer Patients

Moffitt Cancer Center Researchers Analyze HPV Vaccination Disparities among Girls from Low-income Families

ASCO Completes Prototype for CancerLinQ™, Marking First Demonstration of a “Learning Health System” to Transform Cancer Care

Number of Cancer Survivors Expected to Increase to 18 Million by 2022

Monoclonal Antibody Targets, Kills Leukemia Cells

Higher Soy Intake Prior to Lung Cancer Diagnosis Linked to Longer Survival in Chinese Women

Ganetespib Demonstrates Potency against ALK-positive Lung Cancer and Overcomes Crizotinib Resistance

Cancer in Young Adults Is Focus of New Nationwide Study to Be Led by Fred Hutchinson Cancer Research Center Survivorship Program

UC Davis Research Advances Efforts to Prevent Venous Thromboembolism

Pathologists Identify Patterns of Mutations to Help Inform Design of Future Trials

Highlights of the NCCN 18th Annual Conference Include Expert Roundtables, Presentation of New Guidelines for Survivorship

New Imaging Agent Enables Better Cancer Detection, More Accurate Staging

Cancer Drug Shortages Mean Higher Costs and Greater Risk for Patients

Genetic Risk Strategies Needed for Young, Black, Female Breast Cancer Patients, Moffitt Cancer Center Study Shows

Moffitt Cancer Center Researchers Study Use of Dasatinib for Patients with High-risk MDS

Gene Profile May Help Identify Risk for Hormone-sensitive, Hormone-insensitive Breast Cancer

Scientists Find Promising New Target for Triple-negative Breast Cancer

Amgen Announces Results of Phase III Talimogene Laherparepvec Trial in Late-stage Melanoma

Inherited Genetic Variations Have a Major Impact on Childhood Leukemia Risk

Study: Surgery Superior to Radiotherapy in Men with Localized Prostate Cancer

For Smokers, Low Levels of Vitamin D May Lead to Cancer

St. Jude Children's Research Hospital Announces Issuance of U.S. Patent for Genetically Modified Human Immune Cells for Cancer Therapy

NCCN Adds Two New Member Institutions

Radiation Raises Risk of Heart Disease in Women Treated for Breast Cancer

Samuel M. Silver, MD, PhD, Elected Chairman of NCCN Board of Directors

NCCN Issues New Guidelines for Survivorship

High-fat Dairy Products Linked to Poorer Breast Cancer Survival

Survey of Oncology Providers Shows Sequestration Cuts Will Threaten Seniors' Cancer Care and Increase Medicare Costs

IOM Gauges Progress in Goals for Improving the Cancer Clinical Trials System

More Than 60% of Ovarian Cancer Patients Do Not Receive Recommended Treatment, Study Shows

Intraperitoneal Chemotherapy Gives Ovarian Cancer Patients Better Chance of Survival

FDA Approves New Radioactive Diagnostic Imaging Agent to Help Locate Lymph Nodes in Patients with Certain Cancers

Cancer Researchers Discover New Type of Retinoblastoma in Very Young Children

Cervical Cancer Patients More Likely to Survive if Treated at High-volume Medical Facilities

Colon Cancer Patient Advocates and Physicians Urge Congress to Pass Bill Requiring Medicare Coverage of Virtual Colonoscopy

Study Investigates Older Adults' Views on Cancer Screenings

Study Finds Partial Kidney Removal Leads to Greater Survival and Cost Savings for Patients with Kidney Tumors

Indiana University Researchers Earn $3.2 Million Grant to Develop, Improve Therapies for Pancreatic Cancer

Tougher Criteria May Be Needed for African Americans Considering Prostate Cancer Surveillance

Trio of Biomarkers May Help Identify Kidney Cancer in Early Stages

Study Shows Confidence Builds Better Exercise Habits for Cancer Survivors

Tackling Tobacco Consumption and Improving Vaccination Access Are Two of the Best Ways to Reduce Global Cancer Burden

Focal Therapy Offers Middle Ground for Some Prostate Cancer Patients

Involving Other Providers in Palliative Care May Help Meet Growing Demand

Newly Identified Biomarkers May Help Predict Progression of Barrett’s Esophagus to Esophageal Adenocarcinoma

Colonoscopy Screening Reduces Risk of Advanced Colorectal Cancer, Study Shows

Prospective Study Finds Many Children with Retinoblastoma Can Safely Forego Adjuvant Chemotherapy

Zora Brown, Prominent Cancer Research Advocate, Dies at 63

Nearly One in Four Women Newly Diagnosed with Breast Cancer Report PTSD Symptoms

Cancer Doesn’t Change Adolescent Girls’ Desire to Have Children, Study Shows

'Where You’re Treated Matters' in Terms of Cancer Survival

ASCO President: Sequestration Will Have Shattering Impact on Entire U.S. Cancer Enterprise

Philips Receives FDA 510(k) Clearance for MicroDose SI Mammography System

Infusion of Stem Cells and Specially Generated T-cells from Same Donor Improves Leukemia Survival

Obesity, Physical Inactivity Linked with Risk for Certain Molecular Subtype of Colorectal Cancer

Study Shows New Approach Connecting Smokers to Quit Lines Increases Smoking Cessation Treatment Enrollment

Breast Cancer Patients’ Fear of Developing Lymphedema Far Exceeds Risk

FDA Approves Regorafenib for Advanced Gastrointestinal Stromal Tumors

FDA Approves New Treatment for HER2-positive, Metastatic Breast Cancer

Researchers Identify Variations in Four Genes That Are Associated with an Increased Risk of Colorectal Cancer

Inaugural Winners of the Breakthrough Prize in Life Sciences Announced

New Drug Combination Could Prevent Head and Neck Cancer in High-risk Patients

Selumetinib Shown to Reverse Radioiodine Resistance in Some Advanced Thyroid Cancers

New Website Raises Awareness of Uveal Melanoma and the Importance of Prognostic Testing

Risk of Leukemia After Cancer Chemotherapy Persists

Selumetinib Reported to Benefit Patients with Recurrent Low-grade Ovarian Cancer

AACR Hosts Congressional Briefing on Cancer Progress, NIH Funding

Triple-negative Breast Cancer Subtypes Identified Using MicroRNA

FDA Approves Pomalidomide for Advanced Multiple Myeloma

Experimental Drug Combination Selectively Destroys Lymphoma Cells

Researchers Discover Mutations Linked to Relapse Of Childhood Leukemia

Bevacizumab Significantly Improves Survival for Patients with Recurrent and Metastatic Cervical Cancer

Yale Researchers Identify Genes behind Aggressive Endometrial Cancer

NCI Researchers Identify Molecular Link between Metabolism and Breast Cancer

High-dose Vorinostat Effective at Treating Relapsed Lymphomas, Study Finds

FDA Approval of Generic Version of Liposomal Doxorubicin Injection Is Expected to Help Resolve Shortage

Less Invasive Treatment Is Associated with Improved Survival in Early-stage Breast Cancer

MD Anderson Study Finds Qigong Improves Quality of Life for Breast Cancer Patients Undergoing Radiation Therapy

Alex’s Lemonade Stand Foundation Introduces Centers of Excellence Program to Further Childhood Cancer Research

Imatinib Receives New Indication for Children with Acute Lymphoblastic Leukemia

Bevacizumab Approved as Combination Therapy for Metastatic Colorectal Cancer after Progression on First-line Bevacizumab Therapy

Researchers Discover Promising Prognostic Marker for Aggressive Breast Cancer

Nab-paclitaxel plus Gemcitabine Demonstrates Survival Advantage in Phase III Study of Patients with Advanced Pancreatic Cancer

Genetic Basis of High-risk Childhood Cancer Points to Possible New Drug Treatment Strategy

New Model May Help Predict Response to Chemotherapy for Colorectal Cancer

Patients with NSCLC Have Improved Survival If They Use Beta-blockers While Receiving Radiotherapy

Ezatiostat Gets Orphan Designation for Treatment of Myelodysplastic Syndrome

Report to the Nation Shows U.S. Cancer Death Rates Continue to Drop

Dune Medical Devices Receives FDA Approval for the MarginProbe System