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breast cancer

Program Chairs Highlight Abstracts of Interest for the 2013 CTRC-AACR San Antonio Breast Cancer Symposium

The Program Chairs of the 2013 CTRC-AACR San Antonio Breast Cancer Symposium, which will be held December 10–14, 2013, have highlighted what they consider to be the most important abstracts to be presented at the Symposium. In a telebriefing in advance of the December meeting, C. Kent...

breast cancer
issues in oncology

ECC 2013: PI3KCA-Mutant Tumors Not Likely to Respond to Neoadjuvant HER2 Blockade

In patients with early breast cancer receiving anti-HER2 therapy in the NeoALTTO trial, mutations in PIK3CA were associated with lower rates of pathologic complete response, Jose Baselga, MD, reported at the European Cancer Congress 2013 (Abstract 1859) in Amsterdam. In patients treated with the...

breast cancer
gynecologic cancers
issues in oncology

ECC 2013: Continuous Combined Hormone Replacement Therapy Protects Against Endometrial Cancer

According to an analysis of the Women’s Health Initiative, continuous combined use of estrogen plus progestin reduces the risk of endometrial cancer among postmenopausal women. The study was reported at the European Cancer Congress 2013 in Amsterdam (Abstract LBA13) by Rowan Chlebowski, MD,...

breast cancer
issues in oncology

Breast Cancer Treatment in 10 Years: George Sledge, MD, Offers His Predictions

In a keynote lecture during the 2013 Breast Cancer Symposium breast cancer expert and ASCO Past President George Sledge, MD, offered five predictions for the future of the medical management of breast cancer. Dr. Sledge is now Chief of Oncology at Stanford University School of Medicine, Palo Alto,...

issues in oncology
breast cancer

Following Neoadjuvant Chemotherapy, Biomarkers Change in 41% of Breast Cancer Patients

After neoadjuvant chemotherapy, 41% of early breast cancer patients experienced a change in status for the estrogen receptor, progesterone receptor, or HER2 oncogene, researchers from The University of Texas MD Anderson Cancer Center reported at the 2013 Breast Cancer Symposium in San Francisco...

breast cancer
issues in oncology

Could MRI Be a Better Breast Cancer Screening Tool Than Mammography?

German investigators reported at the 2013 Breast Cancer Symposium in San Francisco that an abridged magnetic resonance imaging (MRI) protocol can accurately detect cancers among women whose mammographic screenings were negative (Abstract 1). MRI, therefore, may reveal the type of tumor that...

breast cancer

Study Reveals Best of Three Schedules of Nab-paclitaxel/Bevacizumab in Metastatic Breast Cancer

In a phase II study evaluating three dosing regimens of nanoparticle albumin-bound (nab)-paclitaxel (Abraxane) given with bevacizumab (Avastin), weekly dosing of nab-paclitaxel resulted in the highest overall response rate and longest progression-free survival. The schedule of nab-paclitaxel given...

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