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breast cancer
solid tumors
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issues in oncology
immunotherapy

FDA Pipeline: New Priority Reviews, Designations, and Clearances, Plus Statements on Genetic Testing and Class Labeling

The U.S. Food and Drug Administration (FDA) recently issued the following new approvals and designations: Priority Review for Atezolizumab in Combination With Chemotherapy for the Initial Treatment of Extensive-Stage SCLC The FDA accepted a supplemental biologics license application...

6th Annual Rally for Medical Research Hill Day Advocates for Continued Growth in Federal Funding for the NIH

Nearly 350 organizations—including medical societies and oncology treatments centers—are advocating for robust, sustained, and predictable annual funding increases for the National Institutes of Health (NIH) during the 6th annual Rally for Medical Research Hill Day, taking place...

Alan S. Rabson, MD, Long-Time NCI Deputy Director and Cancer Research Stalwart, Dies at Age 92

MANY IN the cancer research and National Institutes of Health (NIH) community are mourning the loss of long-time National Cancer Institute (NCI) senior leader Alan S. Rabson, MD, who died on July 4 at the age of 92.  With a distinguished scientific career that spanned 6 decades and included...

genomics/genetics

NIH Completes In-Depth Genomic Analysis of 33 Cancer Types

Researchers funded by the National Institutes of Health (NIH) have completed a detailed genomic analysis, known as the PanCancer Atlas, on a data set of molecular and clinical information from over 10,000 tumors representing 33 types of cancer, according to a release issued by the NIH late last...

issues in oncology

NIH Completes In-Depth Genomic Analysis of 33 Cancer Types

Researchers funded by the National Institutes of Health (NIH) have completed a detailed genomic analysis, known as the Pan-Cancer Atlas, on a data set of molecular and clinical information from over 10,000 tumors representing 33 types of cancer. “This project is the culmination of more than...

A Tribute to Two Amazing Scientists

Dr. Collins is Director of the National Institutes of Health. Originally posted on March 19, 2018, to the National Institutes of Health (NIH) Director’s Blog (https://directorsblog. nih.gov).  OVER THE PAST couple of weeks, we’ve lost two legendary scientists who made major contributions to our...

NIH Partners With 11 Biopharmaceutical Companies on PACT Collaboration

On October 12, 2017, the National Institutes of Health (NIH) and 11 leading biopharmaceutical companies launched the Partnership for Accelerating Cancer Therapies (PACT), a 5-year public-private research collaboration totaling $215 million as part of the Cancer Moonshot. PACT will initially focus...

Norman E. Sharpless, MD, Sworn in as Director of the National Cancer Institute

Norman E. “Ned” Sharpless, MD, took the oath of office late Tuesday, October 17, 2017, to become the 15th Director of the National Cancer Institute (NCI), part of the National Institutes of Health (NIH). He succeeds Harold E. Varmus, MD, who stepped down as Director in March 2015. Douglas R. Lowy, ...

Norman E. Sharpless, MD, Sworn in as Director of the National Cancer Institute

Norman E. “Ned” Sharpless, MD, took the oath of office late Tuesday, October 17, 2017, to become the 15th Director of the National Cancer Institute (NCI), part of the National Institutes of Health (NIH). He succeeds Harold E. Varmus, MD, who stepped down as Director in March 2015....

Douglas R. Lowy, MD, and John T. Schiller, PhD, Receive 2017 Lasker Award

Two scientists at the National Cancer Institute (NCI) received the 2017 Lasker-DeBakey Clinical Medical Research Award for their significant research leading to the development of human papillomavirus (HPV) vaccines. The award is the country’s most prestigious biomedical research prize and was...

Douglas R. Lowy, MD, and John T. Schiller, PhD, to Receive 2017 Lasker Award

Two scientists at the National Cancer Institute (NCI) will receive the 2017 Lasker-DeBakey Clinical Medical Research Award for their significant research leading to the development of human papillomavirus (HPV) vaccines. The award is the country’s most prestigious biomedical research prize,...

ASCO Applauds NIH Director Francis Collins, MD, PhD, for Remaining in Critical Leadership Position

ASCO President Bruce E. Johnson, MD, FASCO, released the following statement on June 8: ASCO congratulates Francis S. Collins, MD, PhD, on the announcement of his continued service as the Director of the National Institutes of Health (NIH). A renowned researcher and skilled administrator, Dr....

health-care policy

ASCO Congratulates NIH Director Francis Collins on Remaining in Critical Leadership Position

ASCO President Bruce E. Johnson, MD, FASCO, released the following statement today: “ASCO congratulates Francis S. Collins, MD, PhD, on the announcement of his continued service as the Director of the National Institutes of Health (NIH). A renowned researcher and skilled administrator, Dr....

Philip E. Bourne, PhD, Leaves NIH, Accepts Position at University of Virginia

On January 6, Francis S. Collins, MD, PhD, Director, National Institutes of Health (NIH), issued the following statement: It is with truly mixed emotions that I announce the departure of Philip E. Bourne, PhD, who will be leaving his post as NIH’s first Associate Director for Data Science to...

NIH Statement on the Death of Former Congressman Melvin R. Laird

“I am greatly saddened by the death of former Congressman Melvin R. Laird, who, over the course of his distinguished career in public service, played a key role in advancing biomedical research and the mission of the National Institutes of Health (NIH). Our thoughts are with his family and the...

HHS Takes Steps to Provide More Information on Clinical Trials to the Public

To make information about clinical trials widely available to the public, the U.S. Department of Health and Human Services (HHS) issued a final rule on September 19 that specifies requirements for registering certain clinical trials and submitting summary results information to ClinicalTrials.gov....

health-care policy

FDA Advances Precision Medicine Initiative by Issuing Draft Guidances on Next-Generation Sequencing–Based Tests

In support of the President’s Precision Medicine Initiative, on July 6, the U.S. Food and Drug Administration (FDA) issued two draft guidances that, when finalized, will provide a flexible and streamlined approach to the oversight of tests that detect medically important differences in a...

NIH Appoints Patricia Flatley Brennan, RN, PhD, to Lead the NLM

National Institutes of Health (NIH) Director Francis S. ­Collins, MD, PhD, has named ­Patricia Flatley ­Brennan, RN, PhD, Director of the National Library of Medicine (NLM). The NLM is the world’s largest biomedical library and the producer of digital information services used by scientists,...

Director Selected for NIH’s Precision Medicine Initiative Cohort Program

Francis S. Collins, MD, PhD, Director, National Institutes of Health (NIH), recently released the statement below: I am very pleased to announce the selection of Eric Dishman as Director of the Precision Medicine Initiative (PMI) Cohort Program. Eric will lead NIH’s effort to build the PMI...

Blue Ribbon Panel to Help Guide National Cancer Moonshot Initiative

On April 4, 2016, The National Cancer Institute (NCI), part of the National Institutes of Health (NIH), announced a Blue Ribbon Panel of scientific experts, cancer leaders, and patient advocates that will inform the scientific direction and goals at NCI of Vice President Joe Biden’s National Cancer ...

health-care policy

NCI Announces Blue Ribbon Panel to Help Guide Vice President Biden’s National Cancer Moonshot Initiative

On April 4, 2016, The National Cancer Institute (NCI), part of the National Institutes of Health (NIH), announced a Blue Ribbon Panel of scientific experts, cancer leaders, and patient advocates that will inform the scientific direction and goals at NCI of Vice President Joe Biden’s National...

issues in oncology

Francis Crick's Discovery of the Structure of DNA Transformed 20th Century Biologic Sciences 

“My Dear Michael, Jim Watson and I have probably made a most important discovery. We have built a model for the structure of des-oxy-ribose-nucleic-acid, called DNA for short.… In other words we think we have found the basic copying mechanism by which life comes from life,” wrote Francis Crick,...

issues in oncology
legislation

Supreme Court Rules Human Genes May Not Be Patented 

On June 13, the U.S. Supreme Court ruled unanimously that isolated human genes may not be patented. However, the creation of synthetic forms of DNA, known as complementary DNA (cDNA), is eligible for patent protection. The decision resolves the question brought before the Supreme Court justices in...

issues in oncology

NIH Commits $24 Million Annually for Big Data Centers of Excellence

The National Institutes of Health will fund up to $24 million per year for 4 years to establish six to eight investigator-initiated Big Data to Knowledge Centers of Excellence. The centers will improve the ability of the research community to use increasingly large and complex datasets through the...

NIH Announces 15 Clinical and Translational Science Awards 

Translating basic discoveries into new treatments that tangibly improve human health requires innovative collaborations and resources, as well as a diverse, highly trained workforce. To help meet these needs, the National Institutes of Health recently announced more than $79 million in fiscal year...

NIH Names First Chief Officer for Scientific Workforce Diversity, Hannah Valantine, MD

National Institutes of Health (NIH) Director Francis S. ­Collins, MD, PhD, has appointed Hannah Valantine, MD, to Chief Officer for Scientific Workforce Diversity. Dr. Valantine will lead NIH’s effort to diversify the biomedical research workforce by developing a vision and comprehensive strategy...

issues in oncology

The Future of Biomedical Research

In January, Congress approved a $1 trillion appropriations bill for the rest of fiscal year 2014. While the new bill includes $29.9 billion for the National Institutes of Health (NIH)—$1 billion above FY2013 levels after sequestration—including $4.9 billion for the National Cancer Institute (NCI),...

Yvonne T. Maddox, PhD, Appointed Acting Director of National Institute on Minority Health and Health Disparities

Francis S. Collins, MD, PhD, Director of the National Institutes of Health recently announced the appointment of Yvonne T. Maddox, PhD, as Acting Director of the National Institute on Minority Health and Health Disparities (NIMHHD). This follows the retirement Dr. John Ruffin, NIMHD’s previous...

NIH Opens Its Doors to Research for Extramural/Intramural Collaboration

Ten projects that will enable nongovernment researchers to conduct clinical research at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland, were announced recently. Through these 3-year, renewable awards of up to $500,000 per year, scientists from institutions across the...

health-care policy

The Outlook on Cancer Research in This Era of Leaner Federal Funding

In the March 1, 2014, issue of The ASCO Post we talked with Francis S. Collins, MD, PhD, Director of the National Institutes of Health (NIH), about the future of biomedical research at the NIH during this time of constrained federal funding. We continue that conversation here with our interview of...

ASCO Celebrates Oncology Luminaries for 50th Anniversary

In the 50 years since the American Society of Clinical Oncology was founded, the treatment of cancer has advanced dramatically, due to the work of researchers making important scientific breakthroughs, physicians responsible for delivering those advances to patients, and countless others who...

NIH Awards More Than $30 Million to Enhance Diversity in the Biomedical Research Workforce

The National Institutes of Health (NIH) announced the award of more than $30 million in fiscal year 2014 funds to develop new approaches that engage researchers, including those from backgrounds underrepresented in biomedical sciences, and prepare them to thrive in the NIH-funded workforce. These...

2014 Featured Columnists

The ASCO Post wishes to acknowledge and thank all contributors to the publication during 2014. Here we recognize those who shared their personal thoughts in our Op-Ed department. If you are interested in contributing to The ASCO Post in 2015, write to editor@ASCOPost.com.   Robert Peter Gale, MD,...

Top 10 Articles From The ASCO Post in 2014

The following list presents those articles published in 2014 that were observed most often by visitors to ASCOPost.com, as measured by the number of views.a To view the full version of the articles listed below, visit ASCOPost.com and enter the URL provided below each entry. 1. Continuous...

NIH Recruits Three Lasker Clinical Research Scholars

National Institutes of Health (NIH) has selected three researchers as new Lasker Clinical Research Scholars as part of a joint initiative with the Albert and Mary Lasker Foundation to nurture the next generation of great clinical scientists. This highly competitive program provides talented...

Douglas R. Lowy, MD, Receives Harrington Prize for Innovation in Medicine

The second annual Harrington Prize for Innovation in Medicine has been awarded to oncologist/researcher Douglas R. Lowy, MD, Chief of the Laboratory of Cellular Oncology and Deputy Director of the National Cancer Institute.   The Harrington Prize for Innovation in Medicine, established in 2014 by...

Harold Varmus, MD, Steps Down as NCI Director, Douglas Lowy, MD, Named Acting Director

Harold Varmus, MD, who has led the National Cancer Institute (NCI) at the National Institutes of Health (NIH) for nearly 5 years, has announced that he will step down from his post, effective March 31, 2015. “It has been our great fortune to have Dr. Varmus at the helm of the NCI,” said NIH...

NIH Names Eliseo J. Pérez-Stable, MD, Director of the National Institute on Minority Health and Health Disparities

National Institutes of Health (NIH)Director Francis S. Collins, MD, PhD, has announced the selection of ­Eliseo J. Pérez-Stable, MD, as Director of the National Institute on Minority Health and Health Disparities ­(NIMHD). Dr. Pérez-Stable is expected to join NIH in September 2015. “Dr....

Harold Varmus, MD, Stepping Down as Director of the National Cancer Institute

Harold Varmus, MD, who has led the National Cancer Institute (NCI) at the National Institutes of Health (NIH) for nearly 5 years, has announced that he will step down from his post, effective March 31, 2015. Dr. Varmus will be joining Weill Cornell Medical College's faculty as the Lewis Thomas...

issues in oncology
legislation

Human Genes May Not Be Patented, Rules the Supreme Court

The U.S. Supreme Court ruled unanimously on Thursday that isolated human genes may not be patented. However, the creation of synthetic forms of DNA, known as complementary DNA (cDNA), is eligible for patent protection. The decision resolves the question brought before the Supreme Court justices in...

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