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Alan S. Rabson, MD, Long-Time NCI Deputy Director and Cancer Research Stalwart, Dies at Age 92


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Alan S. Rabson, MD. ©National Cancer Institute

Alan S. Rabson, MD. ©National Cancer Institute

MANY IN the cancer research and National Institutes of Health (NIH) community are mourning the loss of long-time National Cancer Institute (NCI) senior leader Alan S. Rabson, MD, who died on July 4 at the age of 92. 

With a distinguished scientific career that spanned 6 decades and included research on tumor virology and cancer pathology as well as senior leadership roles at NCI, Dr. Rabson was highly respected at NIH and well beyond. Honored time and again for his commitment to science and to advancing cancer research, Dr. Rabson was equally known for treating everybody he encountered—whether a member of Congress, a young researcher in training, or a patient needing advice— with kindness and respect. 

“There have been few people like Alan Rabson,” said NCI Director Norman Sharpless, MD. “The stories of his remarkable history at NCI, his immense dedication to his work, and his love for his family are truly inspiring. It is no overstatement to say that we have lost a giant.” 

Dr. Rabson’s wife of 59 years, Ruth Kirschstein, MD, also was a highly respected and accomplished scientist at NIH. Dr. Kirschstein, who died in 2009, helped organize the research response to the AIDS epidemic and was the first woman to direct an NIH institute, leading the National Institute of General Medical Sciences for 2 decades. 

The couple were known for their deep devotion to NIH and each other. In a 1998 interview, Dr. Rabson recounted: “I started [at NIH] by finishing my last year of pathology training at the Clinical Center. My wife and I liked the place so much that we stayed here for the next 42 years.” 

From Brooklyn to Bethesda 

BORN IN BROOKLYN in 1926, Dr. Rabson spent his first 2 decades mostly in New York, completing his undergraduate degree at the University of Rochester and his medical degree at the State University of New York. 

Remarkably, Dr. Rabson’s first attempt to come to NCI was unsuccessful. Still in medical school, he applied to spend the summer at the institute working for well-known NCI biochemist Jesse Greenstein, PhD. However, it was not to be. Washington, DC, was simply too hot in the summer and there was no air conditioning at the NIH, the eminent scientist explained in response to the young medical student’s request, so he usually worked in Berkeley, California, during those months. 

“There have been few people like Alan Rabson. The stories of his remarkable history at NCI, his immense dedication to his work, and his love for his family are truly inspiring.”
— Norman Sharpless, MD, NCI Director

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During the Korean War, Dr. Rabson joined the Public Health Service’s Commissioned Corps, studying virology, at the Communicable Disease Center (now known as the Centers for Disease Control and Prevention) and the University of Michigan, and pathology, at the U.S. Public Health Service Hospital in New Orleans. 

He finally arrived at the NIH in 1955, as a pathology anatomy resident. Dr. Rabson’s career at NCI began not long after, when he was recruited to study tumor-causing viruses and to serve as a staff member in NCI’s pathology department at the NIH Clinical Center. 

For many years, the NCI Laboratory of Pathology performed the pathology for most of the NIH institutes conducting research at the Clinical Center. The mindset that Dr. Rabson and his colleagues had toward the many people who participated in Clinical Center studies was simple. He said, “We owed them the very, very best we could give them.” 

Dr. Rabson was also legendary in his willingness to help people facing a cancer diagnosis to find the best options for their care, said former NIH Director Francis Collins, MD, PhD. Whether it was a member of Congress or a young mother from the heartland, Dr. Collins recalled, Dr. Rabson always took the time to understand the situation, build a relationship with the patient and family, and help them sift through a myriad of possible clinical trials. 

“Every year since 2012, the NIH Director’s Award ceremony has included the Alan S. Rabson Award for Clinical Care,” Dr. Collins said. “It goes to a deserving employee who demonstrates an exceptional commitment to assisting patients and their families who look to the NIH for help. Al’s half-century of service stands as the epitome of personal dedication to patient care at the National Institutes of Health.” 

After 20 years in the pathology department, Dr. Rabson was named Director of the forerunner to what is now NCI’s Division of Cancer Biology. During that time, he oversaw the division’s transition from an intramural research group that performed its own research to one that also managed the funding of cancer research performed by NCI-supported investigators at institutions across the country. 

Long-Time Leader and Role Model 

THE FINAL STAGE of Dr. Rabson’s distinguished career at NCI began in 1995, when he was named Deputy Director of the institute by then NCI Director Richard Klausner, MD. “He came down to my office on the third floor and said, ‘Would you be willing to be my deputy?’ And I said, ‘I can’t think of anything nicer,’” Dr. Rabson recounted. 

Over the following several decades, he was asked by each new director to continue on in the deputy director role. Current NCI Deputy Director Doug Lowy, MD, described Dr. Rabson’s invaluable service as a sounding board for each director and other NCI leaders on decisions both small and large as among his most important duties. 

“He had an inimitable leadership style,” Dr. Lowy said. “When you talked with him, he spent most of the time trying to understand what you needed, so he could help you, rather than spending it figuring out how you could help him. He truly believed that if you were successful, he was successful.” 

Dr. Rabson held clinical professorships at George Washington University and Georgetown University and received multiple awards from the Public Health Service for his clinical work and scientific contributions. He officially retired from federal service in 2015. That same year, he was named a Scientist Emeritus at the NCI. ■

This article was originally published on the National Cancer Institute website at https://www.cancer.gov/news-events/cancer-currents-blog /2018/alan-rabson-passes-away.


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