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Your search for Jo Cavallo matches 1219 pages

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head and neck cancer

Facing Death and Appreciating Life

I have had to come to terms with my own mortality three times in my life and I’m only 46. When I was 17, I was diagnosed with end-stage renal disease and experienced renal failure 2 years later. I underwent my first kidney transplant at 21, just before starting medical school. Finally, I thought my ...

genomics/genetics

Study Finds Young Adults With Cancer May Harbor Germline Mutations and Benefit From Germline Genetic Testing

According to the National Cancer Institute, each year, about 70,000 adolescents and young adults (AYAs)—those between the ages of 15 and39—are diagnosed with cancer.1 Evidence suggests that some cancers found in AYAs may have unique genetic and biologic features. The findings of a recent study by...

A New Website Offers Support for Adolescent and Young Adults With Cancer During the COVID-19 Pandemic

Although the full impact of the COVID-19 pandemic on patients with cancer is still being evaluated, data from several studies show that in comparison with people who do not have cancer, those who do generally experience a higher risk of severe events including admittance to the intensive care unit, ...

pain management

Understanding the Underlying Mechanisms of Pain in Patients With Cancer

Pain is among the most difficult medical issues for oncologists to confront, said Tony L. Yaksh, PhD, Professor of Anesthesiology and Pharmacology at the University of California, San Diego, during his keynote address at the 2019 Supportive Care in Oncology Symposium. Failure to adequately manage...

health-care policy

Addressing Discrimination and Bias in Medical Education

“As a medical student, I often felt marginalized from my medical community. I have been told that my name is ‘not American,’ fallen prey to being confused for support staff such as a janitor (even while wearing my white coat), and been asked questions like, ‘Where are you really from?’ or ‘How old...

breast cancer
survivorship

Early Screening With MRI May Reduce Breast Cancer Mortality in Survivors of Childhood Cancer Treated With Chest Radiation

The early initiation—at age 25 to 30—of annual breast cancer screening with magnetic resonance imaging (MRI) with or without mammography may reduce breast cancer mortality by more than half in survivors of childhood cancer who had been previously exposed to chest radiation, according to a study by...

issues in oncology

Study Finds Significant Variation in Hispanic Patients’ Trust of Cancer Information Sources

A study by Camacho-Rivera et al published in Cancer Epidemiology, Biomarkers & Prevention examining how increasing knowledge about cancer and cancer services among Hispanic adults may help in reducing inequities to care has found that there is significant variation by ethnicity and other...

issues in oncology

Study Finds Significant Variation in Hispanic Patients’ Trust of Cancer Information Sources

A study by Camacho-Rivera et al published in Cancer Epidemiology, Biomarkers & Prevention examining how increasing knowledge about cancer and cancer services among Hispanic adults may help in reducing inequities to care has found that there is significant variation by ethnicity and other...

health-care policy

Leaders of the PROMISE Study Address Racial Inequities in the United States

In 2018, researchers from Dana-Farber Cancer Institute launched a large, ambitious screening study called PROMISE (ClinicalTrials.gov identifier NCT03689595). The objectives of the study were to identify people with premalignant precursor conditions of multiple myeloma, understand the molecular...

colorectal cancer

I’m Not Too Young for Colorectal Cancer

The first symptoms I had of colorectal cancer—blood in my stool and abdominal pain—coincided with surgery I had to remove my appendix in the spring of 2017. My surgeon attributed the symptoms to the appendectomy and to the medications I received both before and after the surgery. In addition to...

integrative oncology

AIDS Research Led to Appreciation of the Power of Plants and Integrative Medicine in Cancer Care for Donald I. Abrams, MD

The path that led Donald I. Abrams, MD, to a career in oncology was a circuitous one. Although his love of science began when he was a student at Cleveland Heights High School in Ohio, and continued during college at Brown University, where he received an AB in molecular biology in 1972, he was...

palliative care

Determining the Best Place to Die for Patients With Cancer

Studies have shown a disconnect between where patients say they want to die and where they actually die. According to research from Stanford School of Medicine, although an overwhelming majority of Americans—about 80%—would prefer to die at home, just 20% do. In fact, 60% die in acute care...

breast cancer

Improving Care for Women With Late-Stage Breast Cancer

The global toll of breast cancer on women is staggering. In 2018, nearly two million new breast cancer cases were diagnosed, an increase of more than 20% since 2008,1 and mortality rates have increased by 14%, bringing the annual number of deaths worldwide from the cancer to more than 611,625.2...

issues in oncology
hematologic malignancies

Survival Disparities Seen in Hispanic Patients With Blood Cancers Living Near the United States/Mexico Border

A study by Bencomo-Alvarez et al investigating the incidence and survival for Hispanic patients with hematologic malignancies living along the United States/Mexico border in El Paso, Texas, has found that those patients with acute myeloid leukemia, acute lymphoblastic leukemia, or chronic myeloid...

genomics/genetics
solid tumors

Young Adults With Cancer May Benefit From Germline Genetic Testing

According to the National Cancer Institute, each year, about 70,000 adolescents and young adults (AYA)—those between the ages of 15 and 39—are diagnosed with cancer. Evidence suggests that some cancers found in AYA patients may have unique genetic and biologic features. A study that investigated...

cost of care

National Cost of Cancer Care in the United States Expected to Rise to $246 Billion by 2030

According to research from the National Cancer Institute published by Mariotto et al in Cancer Epidemiology, Biomarkers, and Prevention, the national cancer-attributable cost for medical services and prescription drugs is expected to increase from $183 billion in 2015 to $246 billion by 2030—an...

lymphoma

My Future Is Doled Out in Increments of 6 Months

In the fall of 2015, I was looking forward to a trip to Florida for a visit with my daughter and her family, along with a little relaxation. The evening before the trip, I experienced some abdominal pain that my wife, Angela, and I thought might be appendicitis. Concerned the problem could...

issues in oncology

Study Finds Substantial Racial/Ethnic Disparities in Lost Earnings From Cancer Mortality

Disparities in cancer mortality rates between black and white Americans date back more than 60 years. Now, a study by the American Cancer Society comparing person-years of life lost and lost earnings due to premature cancer mortality by race/ethnicity has quantified the economic burden due to...

ASCO’s President Aims to Ensure Equitable Cancer Care for Every Patient

The desire to pursue a career in medicine took root when Lori J. Pierce, MD, FASTRO, FASCO, was a young child visiting family in segregated Ahoskie, North Carolina. She witnessed firsthand the impact the town’s lone African American family physician had on the community. When it came time to...

covid-19

Patients With Cancer Infected With COVID-19 Have More Severe Illness and Higher Mortality Rates Than the General Population

A large cohort study by the COVID-19 and Cancer Consortium evaluating the impact of COVID-19 on patients with cancer has found that all-cause 30-day mortality and severe illness were significantly higher in this population than previously reported in the general population. Mortality and severe...

genomics/genetics
issues in oncology

Precision Medicine Is Becoming a Reality for Pediatric Patients With Cancer

Although 84% of children with cancer survive 5 years or more, children with refractory, relapsed, and progressive high-risk malignancies have a poor median survival of 9.5 months. The German INFORM registry is a large prospective, noninterventional, multicenter study collecting clinical and...

lung cancer
covid-19

Study Finds Patients With Lung Cancer Infected With COVID-19 Are at High Risk for Hospitalization

Data from the global TERAVOLT Consortium, which is investigating the impact of COVID-19 infection on patients with thoracic cancers, have found that these patients are at high risk for hospitalization and death. Prior use of chemotherapy was associated with an increased risk of mortality, as was...

cns cancers
covid-19

Brain Cancer Prepared Me for the Isolation and Uncertainty of the COVID-19 Pandemic

The symptoms of low-grade oligodendroglioma first appeared in the summer of 2003, when I was 12, but they were vague enough—mild headaches and occasional weird sensations on my right side—to ignore. In the fall, I tripped and fell during a game of rollerblade hockey with my classmates and started...

covid-19

How the COVID-19 Pandemic Is Propelling the Delivery of Home Care for Patients With Cancer

In 2019, the Penn Center for Cancer Care Innovation at the University of Pennsylvania’s Abramson Cancer Center began planning a demonstration program, called Cancer Care at Home, to broaden the delivery of oncology treatments to patients in the home setting. The existing services offered by Penn...

issues in oncology

ASCO’s President-Elect Aims to Ensure Equitable Cancer Care for Every Patient

The desire to pursue a career in medicine took root when Lori J. Pierce, MD, FASTRO, FASCO, was a young child visiting family in segregated Ahoskie, North Carolina. She witnessed firsthand the impact the town’s lone African American family physician had on the community. When it came time to...

issues in oncology
covid-19

Overcoming the Challenges of Presenting the ASCO Annual Meeting During the COVID-19 Pandemic

As the worldwide cases of the coronavirus started to mount in February and March, medical societies and organizations monitoring the escalating COVID-19 pandemic and its impact on international and domestic travel made the difficult decision to postpone or cancel their scientific conferences. On...

skin cancer
immunotherapy

Combining Pembrolizumab With IL-12 Electroporation May Improve Clinical Response in Patients With Immunologically 'Cold' Melanoma

Patients with non–immune-infiltrated “cold” tumors have low frequencies of intratumoral tumor-reactive, checkpoint-positive cytotoxic lymphocytes, making them less responsive to checkpoint blockage than patients with immune-infiltrated “hot” tumors. A phase II study by Alain P. Algazi, MD, and...

issues in oncology

Videoconference Intervention Can Reduce Levels of Anxiety and Distress Among Distance Caregivers

According to the National Alliance for Caregiving, the number of adult individuals in the United States providing care for patients with cancer ranges between 2.8 million and 6.1 million. Caregivers for patients with cancer who live more than 1 hour away report having higher levels of anxiety and...

health-care policy
legislation

Study Finds Cancer-Related Deaths Declined in States With Expanded Access to Medicaid

States that adopted Medicaid expansion after passage of the Affordable Care Act (ACA) in 2010 saw a decline in cancer mortality rates by 29% compared with 25% in states that did not expand access to Medicaid, according to a study by Anna Lee, MD, MPH, of Memorial Sloan Kettering Cancer Center, New...

multiple myeloma
covid-19

I Have Multiple Myeloma and Am Concerned About the Coronavirus

In hindsight, the symptoms I began experiencing in the fall of 2013—sudden excruciating back bone pain and severe fatigue—should have tipped me off that I had a serious disease, but 7 years ago, they were easy to explain away. The bone pain was similar to what I had experienced several years...

covid-19
palliative care

Prioritizing Patients With Metastatic Disease for Palliative Radiotherapy

In anticipation of how the COVID-19 pandemic might impact oncology care as the coronavirus spread across New York City, radiation oncologists with expertise in the management of metastatic disease and inpatient oncologic emergencies at Memorial Sloan Kettering Cancer Center (MSK) met in late winter ...

genomics/genetics

AACR 2020: Cell-Free DNA Liquid Biopsy May Provide an Early Detection Test for Patients With Suspected Cancer

The Circulating Cell-free Genome Atlas Study is a large multicenter, case-controlled, observational study of 15,254 participants, 56% with cancer and 44% without cancer, with longitudinal follow-up to support the development of a cell-free DNA (cfDNA) multicancer early detection test. In this phase ...

issues in oncology

AACR 2020: Study Finds Vape Shops Are Mostly Concentrated in Low-Resource, Minority Communities

An analysis investigating the socioecologic context of tobacco and vape shops in Los Angeles has found that vape shops are more likely to be concentrated in low-resource communities. The communities also tended to have higher concentrations of minority residents and fewer tobacco and vaping sales...

lung cancer

AACR 2020: ctDNA May Be a Prognostic Biomarker of Disease Recurrence in Patients With Lung Cancer

The TRACERx study investigated phylogenetic tracking and minimal residual disease (MRD) detection using circulating tumor DNA (ctDNA) profiling following resection in patients with stage I to III non–small cell lung cancer (NSCLC). Investigators found that ctDNA is an adjuvant biomarker capable of...

genomics/genetics

How CRISPR-Cas9 Gene Editing May Improve the Effectiveness of Cellular Therapeutics in Patients With Cancer

The results from the first in-human phase I clinical trial in the United States evaluating CRISPR-Cas9–edited T cells in patients with advanced cancer has shown that the therapy is both feasible and safe, representing a big step forward in the potential of using gene editing to boost the natural...

hepatobiliary cancer

A Clinical Trial Saved My Life

In the fall of 2009, I began experiencing some abdominal discomfort, pain in my right shoulder, and severe fatigue that were easily explained away as the result of gallstones and by my career as a paramedic. I had many of the risk factors for gallbladder disease, and both my mother and sister...

pancreatic cancer

Living A Full Life After Pancreatic Cancer

I have been a radiologic technologist for 47 years, so after going to the bathroom one Sunday morning in October 2018 and finding my urine had suddenly turned dark, I knew something was wrong. I wasn’t in any pain and did not have a urinary tract infection, which would explain the discoloration of...

issues in oncology

What’s in a Name?

When Narjust Duma, MD, Assistant Professor of Medicine and a thoracic oncologist at the University of Wisconsin Carbone Cancer Center in Madison, presented the findings from her study, “Evaluating Unconscious Bias During Speaker Introductions at an International Oncology Conference,” during the...

issues in oncology

Using Respectful Language to Reduce Unconscious Bias in Oncology Care

An abstract presented at the 2019 ASCO Annual Meeting titled “Evaluating Unconscious Bias During Speaker Introductions at an International Oncology Conference,” by Narjust Duma, MD, Assistant Professor of Medicine and Thoracic Oncologist at the University of Wisconsin Carbone Cancer Center in...

covid-19

Maintaining Blood Donations During the COVID-19 Pandemic

A major casualty of the coronavirus disease 2019 (COVID-19) pandemic is the dramatic decrease in the number of blood donations across the United States. As more people are urged to shelter-in-place and avoid social contact, the number of cancellations in blood drives has been dramatic. According to ...

breast cancer

I Wasn’t Prepared for the Emotional Turmoil of Breast Cancer

Nearly a decade ago, my mother tested positive for the BRCA1 mutation; soon after, my twin sister and I were tested for the inherited defective gene, and I learned I, too, have the BRCA1 mutation. My sister is not a carrier of the mutation. Although there is a long history of both breast and...

issues in oncology
survivorship

How Exercise Oncology Can Improve Cancer Outcome and Survivorship

Researchers from the American College of Sports Medicine (ACSM) recently reviewed hundreds of epidemiologic studies on the link between physical activity and both cancer risk and cancer mortality. A subsequent analysis of the findings by a panel of experts representing 17 partner organizations,...

covid-19

Managing Cancer Care During the COVID-19 Pandemic

A special feature in JNCCN–Journal of the National Comprehensive Cancer Network by Ueda et al highlighted the unique circumstances and challenges of providing treatment to patients with cancer during the global COVID-19 pandemic. Physicians from the Seattle Cancer Care Alliance, Fred Hutchinson...

covid-19

Strategies for Protecting Patients and Health-Care Providers Against COVID-19

For Patients Patients undergoing active treatment for cancer and cancer survivors may be at increased risk of becoming infected with the coronavirus because of their compromised immune system and their susceptibility to other illnesses. ASCO has developed information on Cancer.Net on how patients...

covid-19

How COVID-19 Is Affecting the Oncology Community

Over the past month, medical societies worldwide have been monitoring the escalating outbreak of the novel coronavirus and its effect on international and domestic travel and making difficult decisions to cancel or postpone their scientific conferences or make them available digitally. On March...

covid-19

Mitigating the Spread of COVID-19 and Its Impact on Cancer

On March 11, the World Health Organization (WHO) took the step it had been avoiding for weeks and declared that the spread of the coronavirus disease 2019 (COVID-19), and the virus that causes it, now identified as SARS-CoV-2, had reached global pandemic levels, the first pandemic sparked by a...

breast cancer

Therapy Is Keeping My Metastatic Breast Cancer Manageable

Despite being vigilant about adhering to my annual schedule of screening mammography, in 2002, I was diagnosed with stage III triple-negative breast cancer. The diagnosis scared me, and I wondered if I was going to die. Determined to do what I could to survive the cancer, I underwent aggressive...

survivorship

Building Onco-Primary Care to Close the ‘Black Hole’ in Cancer Survivorship Care

When the landmark report from the Institute of Medicine, From Cancer Patient to Cancer Survivor: Lost in Transition, was published in 2006, there were 10 million cancer survivors in the United States.1 Meant to raise awareness of the medical, functional, and psychosocial consequences of a cancer...

breast cancer
issues in oncology
cost of care

Young Women Diagnosed With Breast Cancer May Face Employment Disruption and Financial Hardship

A study evaluating the economic impact of the cancer in young women has found that the diagnosis can result in employment disruption and financial decline. The findings—published by Tangka et al in Cancer Epidemiology, Biomarkers & Prevention—indicate the need for obtaining and maintaining...

issues in oncology

Two Recent Studies Show Low-Nicotine Cigarettes Are Unlikely to Increase Compensatory Smoking

A pair of studies by Smith et al published in Cancer Epidemiology, Biomarkers & Prevention evaluating whether a mandated reduction in the nicotine content of cigarettes may cause smokers to compensate by engaging in compensatory smoking to obtain more nicotine has found that a reduction in...

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