Reshma Jagsi, MD, DPhil, of Emory University Winship Cancer Institute, discusses the IDEA trial of endocrine therapy without radiotherapy after breast-conserving surgery for postmenopausal patients between the ages of 50 and 69 with stage I breast cancer. The regimen demonstrated a low risk of...
Reshma Jagsi, MD, DPhil, of the University of Michigan, and Rachel A. Freedman, MD, MPH, of Dana-Farber Cancer Institute, discuss the twin challenges of overtreating people with cancer and the missed opportunities and dangers of undertreatment.
The American Society for Radiation Oncology (ASTRO) has issued a new clinical guideline for the use of whole-breast radiation therapy for breast cancer that expands the population of patients recommended to receive hypofractionated treatment. The guideline was published by Smith et al in...
In a prospective cohort study reported by Jagsi et al in the Journal of the National Cancer Institute, autologous reconstruction was associated with fewer complications and greater patient satisfaction vs implant approaches in women receiving postmastectomy radiotherapy. Study Details The...
In a new study published by Jagsi et al in JAMA Surgery, nearly half of patients with early-stage breast cancer considered having double mastectomy, and one in six received it—including many who were at low risk of developing a second breast cancer. Many patients who chose double...
Radiotherapy increased complications and impaired patient-reported satisfaction with reconstructed breasts in breast cancer patients who received implant reconstruction, but not in those who received autologous reconstruction, according to data from a large, prospective, multicenter cohort study...
Reshma Jagsi, MD, DPhil, of the University of Michigan Health System, discusses this multicenter phase 1 study of veliparib given concurrently with chest wall and nodal radiation therapy in patients with inflammatory or locoregionally recurrent breast cancer (Abstract 312).
In an analysis reported in JAMA Oncology, Jagsi et al found that hypofractionation of whole-breast radiotherapy was associated with reduced acute toxicity compared with conventional fractionation. Study Details The study involved data on physician-assessed toxic effects and patient-reported...
A University of Michigan survey of women with breast cancer found that nearly half considered having a double mastectomy—but of those who considered it, only 37% knew that the more aggressive procedure does not improve survival for women with breast cancer. Among women who received a double...
A new study from the University of Michigan Comprehensive Cancer Center found that many women diagnosed with breast cancer are concerned about the genetic risk of developing other cancers themselves, or of a loved one developing cancer. These findings were published by Jagsi et al in the Journal of ...
The ACOSOG Z0011/Alliance trial showed that axillary lymph node dissection provides no benefit over sentinel lymph node biopsy in patients with breast cancer with one or two positive sentinel lymph nodes undergoing lumpectomy, radiotherapy, and systemic therapy. In an analysis reported in the...
In a study reported in the Journal of Clinical Oncology, Jagsi et al found that use of breast reconstruction in patients with breast cancer undergoing mastectomy has increased over time but varies according to a number of treatment and demographic characteristics. Study Details The study involved ...