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leukemia
issues in oncology

Researchers Identify Dozens of Genetic Mutations Driving CLL and Their Evolution in Progression and Relapse

An analysis of whole-exome sequencing data from 538 patients with chronic lymphocytic leukemia (CLL), including 278 pretreatment samples collected from patients enrolled in a clinical trial, has identified 44 recurrently mutated genes and 11 recurrent somatic copy number variations. These findings...

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