Dr. Abraham’s Top-10 Picks for the Most Clinically Relevant Breast Cancer Studies of 2015


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  1. Sparano JA, Gray RJ, Makower DF, et al: Prospective validation of a 21-gene expression assay in breast cancer. N Engl J Med 373:2005-2014, 2015.
  2. Chagpar AB, Killelea BK, Tsangaris TN, et al: A randomized, controlled trial of cavity shave margins in breast cancer. N Engl J Med 373:503-510, 2015.
  3. Turner NC, Ro J, André F, et al: Palbociclib in hormone receptor–positive advanced breast cancer. N Engl J Med 373:209-219, 2015.
  4. Himelstein AL, Qin R, Novotny PJ, et al: CALGB 70604 (Alliance): A randomized phase III study of standard dosing vs longer interval dosing of zoledronic acid in metastatic cancer. 2015 ASCO Annual Meeting. Abstract 9501. Presented June 1, 2015.
  5. Toi M, Lee S-J, Lee ES, et al: A phase III trial of adjuvant capecitabine in breast cancer patients with HER2-negative pathologic residual invasive disease after neoadjuvant chemotherapy (CREATE-X, JBCRG-04). 2015 San Antonio Breast Cancer Symposium. Abstract S1-07. Presented December 9, 2015.
  6. Sikov WM, Berry DA, Perou CM, et al: Event-free and overall survival following neoadjuvant weekly paclitaxel and dose-dense AC +/- carboplatin and/or bevacizumab in triple-negative breast cancer: Outcomes from CALGB 40603 (Alliance). 2015 San Antonio Breast Cancer Symposium. Abstract S2-05. Presented December 9, 2015.
  7. Slamon DJ, Eiermann W, Robert NJ, et al: Ten year follow-up of the BCIRG-006 trial comparing doxorubicin plus cyclophosphamide followed by docetaxel with doxorubicin plus cyclophosphamide followed by docetaxel and trastuzumab with docetaxel, carboplatin, and trastuzumab in HER2-positive early breast cancer. 2015 San Antonio Breast Cancer Symposium. Abstract S5-04. Presented December 11, 2015.
  8. Gnant M, Pfeiler G, Dubsky PC, et al: The impact of adjuvant denosumab on disease-free survival: Results from 3,425 postmenopausal patients of the ABCSG-18 trial. 2015 San Antonio Breast Cancer Symposium. Abstract S2-02. Presented December 9, 2015.
  9. Narod SA, Iqbal J, Giannakeas V, et al: Breast cancer mortality after a diagnosis of ductal carcinoma in situ. JAMA Oncol 1:888-896, 2015.
  10. Oeffinger KC, Fontham ET, Etzioni R, et al: Breast cancer screening for women at average risk: 2015 Guideline Update from the American Cancer Society. JAMA 314:1599-1614, 2015.

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