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Skin Cancer

Pembrolizumab Active in Mucosal Melanoma in KEYNOTE Studies

Three clinical trials of the immunotherapy pembrolizumab have shown that it is active against a rare subtype of skin cancer...

Prostate Cancer

Progress in Defining Molecular Signature for Aggressive Androgen-Indifferent Prostate Cancer

Prostate cancer has lagged behind breast cancer in the identification of predictive and prognostic biomarkers, but the field...

Solid Tumors

One Cycle of BEP as Good as Two in High-Risk Testicular Cancer

The approach to treatment of high-risk, clinical stage I, nonseminomatous or combined germ cell tumors...


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More Top Stories

Lung Cancer

Limo Chen, PhD, on Lung Cancer and CD38: Resistance to Immunotherapy

Issues in Oncology

Study Projects HIV-Related Cancer Burden to Decline

The total number of cancer cases diagnosed among people living with the human immunodeficiency virus (HIV) is projected to decline in coming years, due mostly to declines in non-Hodgkin lymphoma and Kaposi sarcoma. Certain other cancers, such as prostate and lung, are expected to rise, according to ...

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Second Cancers May Be Deadlier in Pediatric, Adolescent, and Young Adult Patients

Second cancers in children as well as adolescents and young adults (AYAs) are far deadlier than they are in older adults and may partially account for the relatively poor outcomes of cancer patients aged 15 to 39 years overall, according to a new study by University of California (UC), Davis...

Lung Cancer

Tracey L. Evans, MD, on NSCLC: Combined-Modality Therapy

W.E. ‘Ed’ Bosarge, Jr, PhD, Honored With 2017 AACR Distinguished Public Service Award

The American Association for Cancer Research (AACR) presented an AACR Distinguished Public Service Award to W.E. “Ed” Bosarge, Jr, PhD, in honor of his generous, unstinting contributions to cancer research, innovative medical and environmental science, and the AACR. Dr. Bosarge is known for his...

New Study Finds Global Smoking Rates on Decline but Shows More Work Is Still Needed

On March 21, 2017, Gravely et al published a study1 in Lancet Public Health on the 2003 global tobacco control treaty’s impact on the adoption of tobacco-reduction measures around the world, which has led to a 2.5% reduction in global smoking rates. The treaty obligates the 180 countries committed...

FDA Grants Lorlatinib Breakthrough Therapy Designation for ALK-Positive Metastatic Non–Small Cell Lung Cancer

On April 27, the investigational next-generation ALK/ROS1 tyrosine kinase inhibitor lorlatinib was granted Breakthrough Therapy designation from the U.S. Food and Drug Administration (FDA) for the treatment of patients with anaplastic lymphoma kinase (ALK)-positive metastatic non–small cell...

Prostate Cancer

Charles G. Drake, MD, PhD, on Prostate Cancer and Immunology: Expert Perspective

Roger S. Lo, MD, PhD, Receives Inaugural AACR–Waun Ki Hong Award for Cancer Research

The American Association for Cancer Research (AACR) honored Roger S. Lo, MD, PhD, with the first AACR–Waun Ki Hong Award for Outstanding Achievement in Cancer Research during the 2017 AACR Annual Meeting in Washington, DC. The AACR established this award in recognition of AACR President...

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New 'Bone-in Culture Array' Tests Therapies for Breast Cancer Metastasis

A new laboratory technique developed by researchers at Baylor College of Medicine and other institutions can rapidly test the effectiveness of treatments for life-threatening breast cancer metastases in bone. Findings of this research were published by Wang et al in Nature Communications....


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