Palliative Care

Using Video Decision-Support Tools to Facilitate End-of-Life Discussions With Patients

Research shows that although most Americans, about 80%, would prefer to die at home, only 20% actually do; 60% die in acute care hospitals, and 20% die in nursing homes...

Prostate Cancer

Should We Treat Rising PSA in Men With Castrate Androgen Levels?

In rapid succession, the SPARTAN study results were presented at the 2018 Genitourinary Cancers Symposium, the data were published in The New England Journal of Medicine...

Leukemia

Nilotinib Label Updated to Provide Treatment Discontinuation Recommendations for CML With Sustained Molecular Response

On December 22, 2017, the product label for nilotinib was updated to include information on nilotinib discontinuation, postdiscontinuation monitoring, and guidance for treatment...


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Prostate Cancer

USPSTF Recommendations on PSA-Based Screening for Prostate Cancer

As reported in JAMA, the US Preventive Services Task Force (USPSTF) has issued updated recommendations on prostate-specific antigen (PSA)-based screening for prostate cancer...

Gynecologic Cancers

Long-Term Follow-up of Women With Vaginal and Cervical Clear Cell Adenocarcinoma Associated With DES Exposure

In a letter to the editor of The New England Journal of Medicine, Huo et al described long-term outcomes of women with vaginal and cervical clear cell adenocarcinoma associated...


More Top Stories

Issues in Oncology
Cost of Care

Jeffrey Schwartz, MBA, on Drug Development and the Cost of Researching and Treating Cancer

Listen Now to “Remembering Dad”: Latest Release from Your Stories: Conquering Cancer Podcast

HOW DO patients really feel when they are in your care? What does it feel like to cure a cancer? How are the children of oncologists affected when grief is a parent’s occupational hazard? These are the personal topics explored in the candid and inspirational mini-podcast series, Your Stories:...

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USPSTF Recommendations on PSA-Based Screening for Prostate Cancer

As reported in JAMA, the US Preventive Services Task Force (USPSTF) has issued updated recommendations on prostate-specific antigen (PSA)-based screening for prostate cancer. To inform the recommendations, the USPSTF reviewed evidence on benefits and harms of PSA-based screening and treatment of...

Health-Care Policy

Nancy Goodman, JD, MPP: Is the Federal Government a Productive Partner in Cancer Policy?

AACR Announces 2018 Special Recognition Awards

THE AMERICAN ASSOCIATION for Cancer Research (AACR) presented Special Recognition Awards to the following four individuals whose work has made extraordinary contributions to the AACR’s mission to accelerate the prevention and cure of all cancers through research, education, communication, and...

AACR Welcomes New Leadership at 2018 Annual Meeting

THE AMERICAN ASSOCIATION FOR CANCER RESEARCH (AACR) welcomes Elizabeth M. Jaffee, MD, Deputy Director for the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins and Associate Director of the Bloomberg~Kimmel Institute for Cancer Immunotherapy, as President of AACR for 2018–2019....

CXCR4 Antagonist Plus Eribulin in HER2-Negative Metastatic Breast Cancer

Findings in a phase I trial reported in The Lancet Oncology by Pernas et al indicate activity of the combination of the CXCR4 chemokine receptor antagonist balixafortide plus eribulin in previously treated HER2-negative metastatic breast cancer. The CXCR4–stromal cell-derived factor-1α...

Kidney Cancer

Patrick Schöffski, MD, MPH, on RCC: Final Results of the EORTC 90101 CREATE Trial

Hematologic Malignancies
Leukemia

Nilotinib Label Updated to Provide Treatment Discontinuation Recommendations for CML With Sustained Molecular Response

On December 22, 2017, the product label for nilotinib (Tasigna) was updated to include information on nilotinib discontinuation, postdiscontinuation monitoring, and guidance for treatment reinitiation in patients with Philadelphia chromosome (Ph)-positive chronic myeloid leukemia (CML) who have...

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Long-Term Follow-up of Women With Vaginal and Cervical Clear Cell Adenocarcinoma Associated With DES Exposure

In a letter to the editor of The New England Journal of Medicine, Huo et al described long-term outcomes of women with vaginal and cervical clear cell adenocarcinoma associated with prenatal exposure to the synthetic nonsteroidal estrogen diethylstilbestrol (DES). As noted by the authors, women...