Colorectal Cancer

Small Study Evaluates Treatment Sequencing in Patients With Metastatic Colorectal Cancer

The optimal treatment sequence for two approved agents in metastatic colorectal cancer may be regorafenib before cetuximab, according to results from the small randomized Japanese REVERCE trial...

Hepatobiliary Cancer

In Unresectable Liver Cancer, Progression-Free Survival Doubled When Sorafenib Added to TACE

Sorafenib added to transarterial chemoembolization (TACE) doubled the median progression-free survival over TACE alone in patients with unresectable hepatocellular carcinoma...

Bladder Cancer

Adjuvant Chemotherapy for Upper Tract Urothelial Cancer

Adjuvant chemotherapy achieved robust improvements in disease-free survival and metastasis-free survival compared with surveillance in the phase III POUT study of patients with upper tract urothelial cancer...


More Top Stories

Ann W. Silk, MD, and Katy K. Tsai, MD: Meeting Highlights

Solid Tumors
Skin Cancer

Clinical Trials Actively Recruiting Patients With Melanoma

The information contained in this Clinical Trials Resource Guide includes actively recruiting clinical studies in melanoma. These studies focus on assessing response to checkpoint inhibitors; T-cell immunotherapy; combination therapies; adoptive cell therapy; combination therapy development; and...


AACR 2018: Underserved Populations Lack Information About Clinical Trials, Biobanking

People in Louisiana communities with cancer health disparities would be interested in participating in clinical trials or submitting samples to biobanks if provided information about these opportunities by a trusted physician—but physicians reported lacking appropriate information to give to...

Prostate Cancer

Robert G. Bristow, MD, PhD, on Prostate Cancer: Keynote Lecture

Prostate Cancer

New Agents for Initial Treatment of Metastatic Prostate Cancer: A New Standard of Care?

FOR DECADES, the status of metastatic prostate cancer trials was not particularly exciting. With an absence of high-impact novel agents, the focus of cancer trial groups was on the improvement of standard care. Well-crafted, large trials of hormonal therapy demonstrated the utility of combined...

Second Brazilian Practice Achieves QOPI® Certification

Clinica AMO has become the second practice in Brazil to receive Quality Oncology Practice Initiative (QOPI®) certification through QOPI Certification Program, LLC, and the sixth practice internationally to receive this accreditation. The practice, located in Salvador, Bahia, on Brazil’s east coast, ...

AACR 2018: Chlamydia Infection May Be Associated With Increased Risk of Ovarian Cancer

An antibody that is present in the blood of women previously infected with the sexually transmitted infection chlamydia is associated with a doubling in ovarian cancer risk, according to data presented during a media preview for the 2018 American Association for Cancer Research (AACR) Annual...

Kidney Cancer

Daniel J. George, MD, on RCC: Study Results on Adjuvant Treatment

Lung Cancer

Osimertinib: A New Standard of Care in Initial Treatment of EGFR-Mutant NSCLC

Dr. Ramalingam is Professor of Hematology and Medical Oncology, Emory University School of Medicine, Winship Cancer Institute, Atlanta. MUTATIONS IN the epidermal growth factor receptor (EGFR) gene were discovered in 2004. These mutations, localized most commonly to exon 19 or 21, vary in...


AACR 2018: Prior Chemotherapies May Impair Pediatric Patients’ Ability to Develop Effective CAR T Cells

Pediatric patients with solid tumors may have poor quality T cells compared to patients with leukemia, and certain chemotherapies were detrimental to the T cells and their potential to become chimeric antigen receptor (CAR) T cells, according to data presented during a media preview for the...