Issues in Oncology

Interventions to Address Sexual Problems in People With Cancer: ASCO Clinical Practice Guideline Adaptation of CCO Guideline

As reported in the Journal of Clinical Oncology by Jeanne Carter, PhD, of Memorial Sloan Kettering Cancer Center, and colleagues, ASCO has issued a clinical practice guideline adaptation of the Cancer Care Ontario...

Issues in Oncology

Legal Duties of Clinicians When Terminally Ill Patients With Cancer or Their Surrogates Insist on ‘Futile’ Treatment

For years, ASCO and other medical societies have lamented the persistent overuse of aggressive end-of-life treatment for patients with incurable cancers. Far too many terminally ill patients receive...

Hematologic Malignancies

The WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues

The ASCO Post is pleased to present Hematology Expert Review, an ongoing feature that quizzes readers on issues in hematology. In this installment...


More Top Stories

Solid Tumors

Jeffrey M. Lemons, MD, on Solid Tumors: Safety Data on SBRT and Immunotherapy

Issues in Oncology

Fast Food Nation and America’s Sick Diet

BOOKMARK Title: Fast Food Nation: The Dark Side of the All-American MealAuthor: Eric SchlosserOriginal Publisher: Houghton MifflinOriginal Publication Date: January 2001Price: $23.95, paperback, 288 pages     The Centers for Disease Control and Prevention (CDC) estimates that about two-thirds ...


Fruquintinib in Pretreated Advanced NSCLC

In a Chinese phase II trial reported in the Journal of Clinical Oncology, Lu et al found that the VEGFR-1,-2, and-3 kinase inhibitor fruquintinib was active in patients with advanced nonsquamous non-small cell lung cancer (NSCLC) who progressed after two prior chemotherapy regimens. Study Details ...


Ellin Berman, MD, on CML: Disease Management During Pregnancy

Hepatobiliary Cancer

In Unresectable Liver Cancer, Progression-Free Survival Doubled When Sorafenib Added to TACE

SORAFENIB (Nexavar) added to transarterial chemoembolization (TACE) doubled the median progression-free survival over TACE alone in patients with unresectable hepatocellular carcinoma, Japanese investigators reported at the 2018 Gastrointestinal Cancers Symposium.1 The results of the randomized,...

Supportive Care
Palliative Care

The Challenge of Prognostication in the Era of Immunotherapy

  GUEST EDITOR Addressing the evolving needs of cancer survivors at various stages of their illness and care, Palliative Care in Oncology is guest edited by Jamie H. Von Roenn, MD. Dr. Von Roenn is ASCO’s Vice President of Education, Science, and Professional Development. Although advances in...

Postoperative Chemoradiotherapy vs Radiotherapy in High-Risk Cutaneous Squamous Cell Carcinoma of the Head and Neck

In an Australia-New Zealand phase III trial (Trans Tasman Radiation Oncology Group 05.01) reported in the Journal of Clinical Oncology, Porceddu et al found no benefit of adding carboplatin to postoperative radiation therapy in patients with high-risk cutaneous squamous cell carcinoma of the head...

Hematologic Malignancies

Stephen M. Ansell, MD, PhD, on Hematologic Malignancies: Immunotherapy Update

National Comprehensive Cancer Network Reports New Milestones, Fosters Novel Collaborations

MORE THAN 8 million copies of the National Comprehensive Cancer Network® Clinical Practice Guidelines in Oncology (NCCN Guidelines®) were downloaded in 2017, marking a 16% increase since 2016 and setting a new personal record for the NCCN. Over the past 2 years, free downloads from and the ...


Effect of Single PSA-Based Screening on Prostate Cancer Mortality

In the UK-based CAP trial reported in JAMA, Martin et al found that a single prostate-specific antigen (PSA) screening was not associated with better 10-year prostate cancer-specific survival vs the standard practice of no screening. Screening was associated with greater detection of prostate...