The ASCO Post Provides Multiple Perspectives on Outcome of ODAC Meeting Regarding Bevacizumab in Advanced Breast Cancer

Page last updated at Wednesday, September 01, 2010

The ASCO Post captured initial reactions to the Oncologic Drugs Advisory Committee (ODAC) recommendation that the breast cancer indication for bevacizumab (Avastin) be revoked in interviews with ODAC voting members, breast cancer specialists, oncologists in private practice, third-party payers, and a patient advocate. These reactions are available here at ASCOPost.com and in the September print issue of The ASCO Post.


(Photos, L to R: Sandra M. Swain, MD; Harold J. Burstein, MD; Wyndham Wilson, MD, PhD; Edith P. Perez, MD; Matthew Ellis, MD, BChir, PhD; Kathy S. Albain, MD, FACP; Musa Mayer; Steven Vogl, MD; Joanne Mortimer, MD; Cary Presant, MD, FACP; Eric P. Winer, MD)

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Bevacizumab, ODAC, and the FDA

Page last updated at Thursday, August 26, 2010

The Oncologic Drugs Advisory Committee (ODAC) of the FDA has recommended that the Agency revoke approval of bevacizumab (Avastin) in first-line treatment of metastatic breast cancer. The FDA will decide whether or not to accept this recomendat...

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Nine Members of the Oncology Community Speak Out about Bevacizumab's Role in Metastatic Breast Cancer

Page last updated at Wednesday, September 01, 2010

The oncology community was recently stirred with potentially practice-changing news: the 12-to-1 vote by the FDA's Oncologic Drugs Advisory Committee (ODAC) to remove the advanced breast cancer indication for bevacizumab (Avastin). The Committee's vote does not affect the current availability of the popular drug, but should the FDA follow ODAC's recommendation-as is its usual practice-the m...

ODAC Voting Members Discuss Panel's Recommendation about Bevacizumab in Advanced Breast Cancer

Page last updated at Thursday, August 26, 2010

Wyndham Wilson, MD, PhDThe recent recommendation by the Oncologic Drugs Advisory Committee (ODAC) to withdraw conditional approval of bevacizumab (Avastin) in combination with chemotherapy for previously untreated metastatic breast cancer has been received with controversy. While many are genuinely concerned about wit...

For Bevacizumab, Third-party Payers Look to NCCN

Page last updated at Thursday, August 26, 2010

The FDA's Oncologic Drugs Advisory Committee (ODAC) concluded that bevacizumab (Avastin) conveys little benefit in advanced breast cancer, but the occasional patient has prolonged remission wit...

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Answering Questions Your Patients May Ask about the Role of Bevacizumab in Metastatic Breast Cancer

Page last updated at Monday, August 30, 2010

When the FDA issued an accelerated approval for the use of bevacizumab (Avastin) for metastatic breast cancer, the approval was contingent on additional clinical trials demonstrating efficacy f...

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Multiparameter Gene Profile Assays for Predicting Recurrence of Colon Cancer

Page last updated at Wednesday, September 01, 2010

This year saw the introduction of the first commercially available multiparameter gene profile assay for predicting risk of recurrence of colon cancer after surgery. The Oncotype DX co...

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Radiation Therapy Not Necessary for Some Elderly Patients with ER-positive Breast Cancer

Page last updated at Wednesday, September 01, 2010

Elderly women with estrogen receptor (ER)-positive early breast cancer may be able to safely forgo radiation therapy after lumpectomy, according to data from a large Intergroup trial presented ...

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