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Prostate Cancer

PARP Inhibitors Moving Ahead in Prostate Cancer

Multiple poly (ADP-ribose) polymerase (PARP) inhibitors are under study in metastatic prostate cancer and no clear winner has emerged yet...

Immunotherapy
Issues in Oncology

Antibiotic Treatment Prior to Immune Checkpoint Inhibitor Therapy Shows Detrimental Effect on Response and Survival

Use of antibiotics prior to checkpoint blockade therapy may attenuate anticancer activity, according to data presented at the 2019 ASCO–Society for Immunotherapy of Cancer (SITC) Clinical Immuno-Oncology Symposium...

Lymphoma

City of Hope Awarded Lymphoma SPORE Grant

City of Hope announced recently that it received its third lymphoma Specialized Programs of Research Excellence (SPORE) grant from the National Cancer Institute...


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Breast Cancer
Genomics/Genetics

American Society of Breast Surgeons Recommends Genetic Testing for Newly Diagnosed Patients With Breast Cancer

In a move that is a significant departure from current testing recommendations, the American Society of Breast Surgeons (ASBrS) recommends that genetic testing be available to all individuals...

Issues in Oncology

NCCN Summit Tackles Inequities in Access to Care

When Brandon Canyon's mother, Leone, was diagnosed with uterine cancer, he drove her to treatment sessions at the nearest cancer center—a 200-mile round trip on rough roads...

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More Top Stories

Bladder Cancer

Brian C. Baumann, MD, on Bladder Cancer: Trial Results on Adjuvant Chemoradiotherapy vs Adjuvant Radiotherapy Alone

Kidney Cancer

Actively Recruiting Clinical Trials Focused on Treatments of Kidney Cancer

The information contained in this Clinical Trials Resource Guide includes actively recruiting clinical studies that are focused on several different kinds of treatments for kidney cancer. These trials are evaluating gene therapy, immunotherapy, chemotherapy, radiotherapy, and combinations thereof. ...

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Immunotherapy Directed Against Precancerous Skin Lesions May Prevent Squamous Cell Carcinoma

A treatment previously shown to treat the precancerous skin lesions called actinic keratosis now appears to also reduce the chance that these pretreated lesions will develop into squamous cell carcinoma. In a report published by Rosenberg et al in JCI Insight, researchers found that treatment with...

Lung Cancer
Immunotherapy

Leora Horn, MD, on Small Cell Lung Cancer and Immuno-oncology: Have We Finally Solved the Small Cell Paradox?

Fred R. Hirsch, MD, PhD, Named Executive Director of New Center for Thoracic Oncology at Mount Sinai

Fred R. Hirsch, MD, PhD, an authority on lung cancer treatment and research, has joined Mount Sinai Health System as Executive Director of the newly created Center for Thoracic Oncology in The Tisch Cancer Institute at Mount Sinai and will also serve as the Richard M. Stein, MD, Joe Lowe, and...

Breast Cancer
Immunotherapy

IMpassion130 Substudy: Atezolizumab/Nab-Paclitaxel Survival Benefits Limited to PD-L1–Positive Triple-Negative Breast Cancer

THE PHASE III IMpassion130 trial, first reported at the European Society for Medical Oncology (ESMO) 2018 Congress1 and published in The New England Journal of Medicine,2 found that the combination of front-line atezolizumab plus nab-paclitaxel significantly improved disease-free and overall...

FDA Pipeline: Safety Warning About Investigational Use of Venetoclax in Multiple Myeloma, Warning Letter on Unapproved Products

This week, the U.S. Food and Drug Administration (FDA) posted a safety statement on the investigational use of venetoclax in multiple myeloma, and also posted a warning letter against a company for illegally marketing unapproved products labeled as homeopathic. Safety Statement The FDA posted...

Prostate Cancer
Immunotherapy

Sumit K. Subudhi, MD, PhD, on Prostate Cancer: Results From the CheckMate 650 Trial on Nivolumab and Ipilimumab

Sarcoma

Sarcoma Coalition Launched as Collaboration of Advocacy Organizations

Those dealing with sarcoma know that resources and support can be difficult to find. Members of the newly formed Sarcoma Coalition are working together to change that. The Sarcoma Coalition is a nonprofit collaboration of sarcoma advocacy organizations from around the country working toward a...

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Artificial Intelligence vs Radiologists in Breast Cancer Detection With Digital Mammography

In a study reported in the Journal of the National Cancer Institute, Rodriguez-Ruiz et al found that a stand-alone artificial intelligence (AI) system had accuracy comparable to an average breast radiologist in detecting breast cancer using digital mammography. Study Details In the retrospective...