Solid Tumors
Issues in Oncology

New Techniques in Intraoperative-Guided Imagery May Enhance Outcomes in Patients With Cancer

Primary treatment of most solid tumors includes surgical excision or radiation therapy, both of which require precise anatomic localization of the tumor as well as surrounding tissue and organs. If the targeting is too broad, unnecessary morbidity may occur to nearby structures, along with the possibility of poor outcomes. To shed light on new techniques in intraoperative-guided imaging, The ASCO Post recently spoke with Michelle S. Bradbury, MD, PhD, Director of Intraoperative Imaging, Radiology, at Memorial Sloan Kettering Cancer Center, New York.

Palliative Care

Closing the Gender Divide in Preference for Palliative Care

Eight years ago, a survey of the preferences of Dutch patients with cancer for health care found that while gender was one aspect influencing how men and women approach cancer care, it was the most important, with men, generally, regarding most care aspects as less important than women. The study concluded that to achieve optimal cancer care, physicians should tailor their communication, manner and extent of support, and consultation length, among other facets of care, based on a patient’s sex.1

Survivorship

Getting Their Lives Back: Helping Survivors of Cancer to Move Forward

Thirteen years ago, Stephanie Koraleski, PhD, an oncology psychologist, and Kay Ryan, PhD, RN, a cardiac nurse and breast cancer survivor, in Omaha, brought together colleagues in the fields of clinical research, nursing, nutrition, mental health, physical therapy, pharmacy, and spirituality to build a cancer rehabilitation program that incorporated a holistic approach to survivorship to fill a care gap left after treatment ends.

 


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Breast Cancer
Survivorship

Living a Purposeful Life Is My Revenge on Cancer

There is a lot of breast cancer in my family history. My mother was diagnosed with the disease at 44, and my paternal grandmother died of breast cancer when she was just 33, so I’ve always been diligent about performing breast self-exams— often weekly—to ensure that if I did get breast cancer, it would be caught at an early, curable stage. I’ve also always lived a healthy lifestyle to reduce my risk of cancer and other diseases. A never-smoker and drinker, I made sure to hit the gym at least 5 days a week to retain my physical stamina and normal weight. I’m also someone who pays attention to the rhythms of her body, so, 4 years ago, when I started feeling bloated and fatigued, I pestered my general practitioner to perform some tests to see what might be wrong.

 

Legislation

Why Oncologists Should Decline to Participate in the Right to Try Act

On May 30, 2018, President Donald J. Trump signed into law the Trickett Wendler, Frank Mongiello, Jordan McLinn, and Matthew Bellina Right to Try Act of 2017.1 This law creates an additional and alternative pathway for patients with a “life-threatening disease or condition” to access investigational medicines outside the clinical trial system. Since there are more than 1,100 cancer medicines currently under investigation, this law will materially impact oncology patients and clinicians.2 Specifically, because of the sense of hope and expectation that the new law has created, increasing numbers of patients with cancer will be asking their oncologists questions about the Right to Try Act.3


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Epacadostat Plus Anti–PD-1 Immunotherapy in Advanced Solid Tumors

As reported by Mitchell et al in the Journal of Clinical Oncology, the combination of the oral indoleamine 2,3-dioxygenase 1 (IDO1) enzyme inhibitor epacadostat and the anti–programmed cell death protein 1 (PD-1) therapy pembrolizumab (Keytruda) showed activity in advanced solid tumors in the ...

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Johns Hopkins Radiation Oncology Pioneer, Moody Wharam, Jr, MD, Dies at 77

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Estradiol as Potential Treatment for Subset of Triple-Negative Breast Cancers

Mayo Clinic researchers have identified estradiol as a potential new treatment for a subset of women with triple-negative breast cancer. Their findings were published by Reese et al in the Proceedings of the National Academy of Sciences of the United States of America. “Triple-negative...

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Robert M. Jotte, MD, PhD, on NSCLC: Results From the IMpower131 Trial

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Assessment of the 8th Edition of the AJCC TNM Staging System in Cohort With Resected Pancreatic Cancer

In a study reported in JAMA Surgery, van Roessel et al found that the recently released 8th edition of the American Joint Committee on Cancer (AJCC) tumor-node-metastasis (TNM) staging system for pancreatic cancer provided better distribution among cases and some increase in prognostic...


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