Breast Cancer

Results of Two Practice-Changing Breast Cancer Trials Upheld

Results of two pivotal breast cancer trials reported at the 2016 ASCO Annual Meeting confirmed the practice-changing findings that...

Issues in Oncology
Health-Care Policy
Cost of Care

Charting a New Course at the FDA

In February, after serving for a year as the U.S. Food and Drug Administration’s (FDA’s) Deputy Commissioner for Medical Products...

Health-Care Policy

CMS Proposal for Part B Drug Payment: A Poorly Conceived Experiment

On March 11, 2016, the Centers for Medicare & Medicaid Services (CMS) issued a proposed rule in the Federal Register to test a change in...


More Top Stories


Steven P. Treon, MD, PhD, on Treating Lymphoplasmacytic Lymphoma/Waldenström’s Macroglobulinemia

Hematologic Malignancies

Complexities in the Diagnosis and Management of Amyloidosis

Case Study

A 70-year-old man is referred to your clinic for a consultation. Recently, a diagnosis of IgG monoclonal gammopathy of undetermined significance (MGUS) was established. Medical history is significant for essential hypertension, type II diabetes mellitus, hyperlipidemia, and atrial...


New ASTRO Clinical Practice Statement Updates Treatment Standard for Rectal Cancer

The American Society for Radiation Oncology (ASTRO) recently issued a new clinical practice statement, “Appropriate Customization of Radiation Therapy for Stage II and III Rectal Cancer: An ASTRO Clinical Practice Statement Using the RAND/UCLA Appropriateness Method.” An executive...


Julie M. Vose, MD, MBA, on Highlights of Pan Pacific Lymphoma 2016

AACR Awards Four Inaugural NextGen Grants for Transformative Cancer Research

The American Association for Cancer Research (AACR) congratulates the four recipients of the inaugural NextGen Grants for Transformative Cancer Research.

The recipients were honored at the AACR Annual Meeting 2016, held April 16–20 in New Orleans.

“The AACR is very proud to announce the first...

Colorectal Cancer

Thriving With Cancer

Seven years ago, at age 44, I was the picture of health. I played tennis every day, went bike riding and lifted weights several times a week, and made sure I ate a healthy diet. The closest I had ever come to cancer was caring for my mother during her 2-year illness with esophageal cancer. As it...

Pap Smear Screenings May Help Prevent Cervical Cancer in Women Over 65

A new study from the University of Illinois confirms a link between Papanicolaou (Pap) smear screenings and a lower risk of developing cervical cancer in women over age 65. However, most American health guidelines discourage women in that age range from receiving screenings unless they have...

Breast Cancer

Nikhil Wagle, MD, on The Metastatic Breast Cancer Project: Progress Report


Increased Risk for Cardiovascular Events Seen in Patients With CML Taking Tyrosine Kinase Inhibitors

Although tyrosine kinase inhibitors have dramatically increased survival for patients with chronic myeloid leukemia (CML), continuous administration of these drugs may elicit long-term toxicity, including cardiovascular adverse events. To investigate the incidence of vascular events in patients...


Hematologic Oncologists Surveyed on Quality Measures of End-of-Life Care and Barriers to Such Care

In a study reported in the Journal of Clinical Oncology, Odejide et al surveyed hematologic oncologists to identify acceptable end-of-life-care quality measures and asked the clinician to identify barriers to such care. Respondents considered unrealistic patient expectations the top barrier to...