A new approach to understanding why T cells are often too weak to fight and destroy tumor cells has earned Yale Cancer Center researchers team science award from the Sokoloff Family-Melanoma Research Alliance.
The $900,000 award will fund research over 3 years examining metabolic regulation of tumor immune response by the microenvironment.
The team includes Marcus Bosenberg, MD, PhD, Associate Professor of Dermatology and Pathology; Susan Kaech, PhD; Richard Kibbey, MD, PhD; and Sidi Chen, PhD. The experiments proposed required the diverse expertise of team members, which includes melanoma biology, immunology, metabolism, and genomic techniques. ■