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Actively Recruiting Clinical Trials Focused on Cancer Prevention


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The information contained in this Clinical Trials Resource Guide includes actively recruiting clinical studies focused on preventing cancer. These studies are investigating a multitude of methods, including educational interventions; imaging devices; dietary changes/supplements; weight management; community outreach; and more. All of the studies are listed on the National Institutes of Health website at ClinicalTrials.gov.

Study Title: Getting Ahead for Cancer Control

Study Type: Interventional/single-group assignment

Study Sponsor and Collaborators: Case Comprehensive Cancer Center

Purpose: To study whether the Getting Ahead program, applied in safety net practices with primary care patients living in poverty, will improve cancer prevention and early detection activities, mediated by a shift in future orientation gained through the program

Primary Outcome Measures: Change in composite score of cancer prevention [time frame: from baseline up to 3 years]

Principal Investigator: Heidi Gullett, MD, Case Comprehensive Cancer Center; (216) 368-0776, heidi.gullett@case.edu

ClinicalTrials.gov Identifier: NCT03247634

 

Study Title: Low-Cost Imaging for Cervical Cancer Prevention in the Texas Lower Rio Grande Valley

Study Type: Interventional/single-group assignment

Study Sponsor and Collaborators: Case Comprehensive Cancer Center

Purpose: To evaluate the effectiveness of utilizing a high-resolution microendoscope for the diagnosis of cervical precancerous lesions and cervical cancer

Primary Outcome Measures: Diagnostic accuracy of the high-resolution microendoscopy [time frame: 1 day]

Principal Investigator: Ana M. Rodriguez, MD, The University of Texas Medical Branch, and Kathleen Schmeler, MD, MD Anderson Cancer Center. Contact Dr. Rodriguez, (409) 772-6767, an3rodri@utmb.edu

ClinicalTrials.gov Identifier: NCT02714439

 

Study Title: Nanoemulsion Curcumin for Obesity, Inflammation, and Breast Cancer Prevention: A Pilot Trial

Study Type: Interventional/parallel assignment

Study Sponsor and Collaborators: The Ohio State University Comprehensive Cancer Center

Purpose: To study a nanoemulsion formulation of curcumin in reducing inflammatory changes in breast tissue in obese women at high risk for breast cancer

Primary Outcome Measures: Determine the adherence, tolerability, and safety of two doses of nanoemulsion curcumin in women at high risk for developing breast cancer [time frame: up to 3 months]

Principal Investigator: Lisa Yee, MD, The Ohio State University Comprehensive Cancer Center; (614) 293-6654, lisa.yee@osumc.edu

ClinicalTrials.gov Identifier: NCT01975363

 

Study Title: Scale Down: A Randomized, Controlled Weight Management Intervention for Women With Endometrial Cancer

Study Type: Interventional/parallel assignment

Study Sponsor and Collaborators: Washington University School of Medicine, Scale Down

Purpose: To pilot a weight management program for patients with endometrial cancer (the cancer most associated with obesity). If successful, other obstetricians and gynecologists could use this strategy for obese women as a practical cancer prevention strategy for obesity-associated cancers.

Primary Outcome Measures: Mean weight loss compared between the two arms [time frame: up to 12 months]

Principal Investigator: Andrea Hagemann, MD, Washington University School of Medicine; (314) 362-1763, hagemanna@wustl.edu

ClinicalTrials.gov Identifier: NCT03169023

 

Study Title: The Beans to Enrich the Gut Microbiome vs Obesity’s Negative Effects (BE GONE) Trial

Study Type: Interventional/crossover assignment

Study Sponsor and Collaborators: MD Anderson Cancer Center

Purpose: To learn whether eating canned, precooked beans can help improve the levels of healthy bacteria in the digestive system and reduce the effects of obesity on cancer risk

Primary Outcome Measures: Changes in stool 16S rRNA gene profiles [time frame: baseline to week 8, serial stool samples collected over each crossover period]

Principal Investigator: Carrie Daniel-MacDougall, PhD, MD Anderson Cancer Center; (713) 563-5783, begone@mdanderson.org

ClinicalTrials.gov Identifier: NCT02843425

 

Study Title: A Community-Based Approach to Reducing Rural Cancer Disparities, Aim 2

Study Type: Observational/case control

Study Sponsor and Collaborators: University of Wisconsin, Madison; National Cancer Institute; American Cancer Society

Purpose: To evaluate the impact of participation in Cancer Clear and Simple educational sessions on cancer prevention and screening

Primary Outcome Measures: Change in behavioral intent [time frame: up to 3 weeks]

Principal Investigator: Elizabeth James, MD, University of Wisconsin, Madison; contact (800) 622-8922, cancerconnect@uwcarbone.wisc.edu

ClinicalTrials.gov Identifier: NCT02973022

 

Study Title: Sun Safety Ink! A Sun Safety Program for the Tattoo Community

Study Type: Interventional/parallel assignment

Study Sponsor and Collaborators: Klein Buendel, Inc.; National Cancer Institute; University of Colorado, Denver

Purpose: To evaluate a skin cancer prevention program targeted to clients of licensed tattoo studios (because tattoo after-care recommendations can include sun protection for tattoos, and studios offer an opportunity to reach younger adults, who are significantly more likely to sunburn and less likely to practice sun safety)

Primary Outcome Measures: Change in sun protection by client (online survey), change in number of sunburns [time frame: baseline, 1 month posttest, 6 months posttest]

Principal Investigator: Barbara Walkosz, PhD, Klein Buendel, Inc.; contact Laura McLaughlin, (303) 565-4336, lmclaughlin@kleinbuendel.com, or Rachel Eye, (303) 565-4328, reye@kleinbuendel.com

ClinicalTrials.gov Identifier: NCT03096548 ■

Editor’s Note: The clinical trials presented here do not represent all the trials listed on ClinicalTrials.gov. For the complete list, go to ClinicalTrials.gov


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