Raymond N. DuBois, MD, PhD, FAACR
THE AMERICAN ASSOCIATION for Cancer Research (AACR) recently recognized Raymond N. DuBois, MD, PhD, FAACR, with the 13th Margaret Foti Award for Leadership and Extraordinary Achievements in Cancer Research during the 2019 AACR Annual Meeting in Atlanta.
Dr. DuBois is Dean of the College of Medicine at the Medical University of South Carolina and Professor in the Departments of Biochemistry, Molecular Biology, and Medicine. He is recognized for his accomplishments in the early detection, interception, and prevention of colorectal cancer.
Dr. DuBois discovered the mechanistic function of prostaglandins and cyclooxygenase in colon cancer initiation and progression, clarified the role of prostaglandins in the tumor microenvironment, and spearheaded the consideration of aspirin and other nonsteroidal anti-inflammatory mediators for cancer prevention.
The Margaret Foti Award for Leadership and Extraordinary Achievements in Cancer Research was established in 2007 to recognize a champion of cancer research whose leadership and extraordinary achievements in cancer research have had a major impact on the field. Such achievements may include scientific contributions to the acceleration of progress against cancer, significant accomplishments associated with national or international awareness of the importance of cancer research, or other ways of demonstrating a sustained extraordinary commitment to cancer research.
Dr. DuBois is known for his discoveries elucidating the connection among inflammation, inflammatory mediators, and early changes responsible for progression of colorectal cancer. His work in this area demonstrated the role of anti-inflammatory agents in the tumor microenvironment, resulting in the design of various clinical trials outlining a role for anti-inflammatory agents in the reduction of cancer risk and progression.
Accomplishments and Professional Training
DR. DUBOIS is Past President of the AACR, Chairman and President of the AACR Foundation, a Fellow of the AACR Academy, and has served as a member of the AACR Board of Directors. In addition, he is Co–Editor-in-Chief of Cancer Prevention Research, has served as an editorial board member of Clinical Cancer Research, and served as Associate Editor of Cancer Research. He also serves as Vice-Chair of the Stand Up To Cancer Scientific Advisory Committee.
Before joining the Medical University of South Carolina, Dr. DuBois was Executive Director of the Biodesign Institute and Dalton Professor of Chemistry and Biochemistry at Arizona State University. Dr. DuBois earned his bachelor’s degree in biochemistry with honors from Texas A&M University and his PhD from The University of Texas Southwestern Medical Center in Dallas. He obtained a medical degree from The University of Texas Health Science Center in San Antonio, followed by an Osler Medicine internship and residency, and a gastroenterology fellowship at The Johns Hopkins Hospital in Baltimore. He is also a fellow of the American Association for the Advancement of Science and Past President of the Southern Society for Clinical Investigation, as well as for the International Society for Gastrointestinal Cancer. ■