ASCO Issues New Guideline on Chemotherapy Dosing for Obese Patients

May 15, 2012, Volume 3, Issue 8

In April, ASCO released a new clinical practice guideline on the appropriate dosing of chemotherapy drugs given to obese adult patients with cancer. The result of an analysis by a panel of experts assembled...

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Advances in Prostate Cancer Accompanied by Ongoing Debates

May 15, 2012, Volume 3, Issue 8

Scientific advances have markedly improved prostate cancer survival, but this clinical success story is not without its share of controversy. From screening through treatment, a growing array of options offer an ...

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Managing Febrile Neutropenia: What Are the Best Antibiotic Regimens?

May 15, 2012, Volume 3, Issue 8

Management of patients with cancer who have fever and a low neutrophil count is one of the most common scenarios oncologists face today. “Physicians have to be keenly aware of the infection risks, diagnostic methods, and microbial therapies required for managing febrile neutr...

Untreated Cancer Pain Remains a Significant Global Problem

May 15, 2012, Volume 3, Issue 8

“Physicians are afraid of morphine … Doctors [in Kenya] are so used to patients dying in pain … they think that this is how you must die. They are suspicious if you don’t die this way — [and feel] that you died prematurely.”

—Human Rights Watch interview with...

Study Reports on New Potential Biomarker of Response in Lung Cancer Chemoprevention Studies

May 15, 2012, Volume 3, Issue 8

MiRNAs, negative post-transcriptional regulators of gene expression, are involved in bronchial carcinogenesis from the very early steps of this process. Endobronchial histology is currently considered as the best intermediate endpoint for chemo...

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Vandetanib: New Drug for Unresectable Medullary Thyroid Cancer

May 15, 2012, Volume 3, Issue 8

In the Clinic provides overviews of novel oncology agents, addressing indications, mechanisms, administration recommendations, safety profiles, and other essential information needed for the appropr...

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More New Data Support Use of Daily Aspirin to Prevent Cancers

May 15, 2012, Volume 3, Issue 8

Three new studies have added data to the growing evidence that low-dose, daily aspirin helps prevent colorectal cancer and other malignancies and may be useful in preventing metastases as well.1-3 Coming on the heels of other recent ...

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Chemoradiation with Fluorouracil and Mitomycin Reduces Recurrence of Muscle-invasive Bladder Cancer

May 15, 2012, Volume 3, Issue 8

Radiotherapy is an alternative to surgery in muscle-invasive bladder cancer, particularly in less-fit patients. However, it is associated with high rates of incomplete response or recurrence, with salvage surgery often being required. Although ...

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