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COVID-19

FDA Issues Emergency Use Authorization for Remdesivir for Treatment of Severe COVID-19

The U.S. Food and Drug Administration (FDA) has issued an emergency use authorization (EUA) for the investigational antiviral drug remdesivir for the treatment of suspected or laboratory-confirmed COVID-19 in adults and children hospitalized with severe disease. Severe disease is defined as low...

COVID-19

ASCO Survey on Early Impact of COVID-19 on the Performance of Oncology Clinical Trials

An article by Waterhouse et al in JCO Oncology Practice presented results of a recent ASCO survey of clinical programs exploring the early impact of the COVID-19 pandemic on the performance of oncology clinical trials. Results highlighted the numerous issues faced by the programs, steps that are...

multiple myeloma
covid-19

Saad Z. Usmani, MD: In My Experience Question 4

For patients with multiple myeloma who are currently on clinical trials, what are the most pressing issues as we fight COVID-19? Recorded April 24, 2020.

multiple myeloma
covid-19

Saad Z. Usmani, MD: In My Experience Question 3

Because of the COVID-19 pandemic, has your management strategy changed for post-transplant consolidation and maintenance therapy in patients with multiple myeloma? Recorded April 24, 2020.

multiple myeloma
covid-19

Saad Z. Usmani, MD: In My Experience Question 2

During the COVID-19 pandemic, do you suggest delaying upfront autologous transplant for patients with multiple myeloma? Recorded April 24, 2020.

covid-19
global cancer care

Rafal Dziadziuszko, MD, PhD, on Using Telemedicine During the Pandemic: Experience in Poland

Rafal Dziadziuszko, MD, PhD, of the Medical University of Gdansk, talks about the adjustments to cancer care that he and his colleagues have made, how and when they employ telemedicine, and whether the technology could change the future for clinical practice. Filmed April 24, 2020.

multiple myeloma
covid-19

Saad Z. Usmani, MD: In My Experience Question 1

As a result of COVID-19, has your decision model for front-line therapy changed for patients with multiple myeloma who are either transplant-eligible or ineligible? Recorded April 24, 2020.

covid-19
global cancer care

Rafal Dziadziuszko, MD, PhD, on Helping Ease Oncology Patients’ Fears of Contracting COVID-19

Rafal Dziadziuszko, MD, PhD, of the Medical University of Gdansk, discusses the concerns his patients with cancer have about exposure to COVID-19 when they come to his institution for care and how he manages their fears. Filmed April 24, 2020.

Immunotherapy
COVID-19

Negotiating the Obstacles to Conducting Clinical Trials of Immunotherapy During the Coronavirus Pandemic

Coronavirus disease 2019 (COVID-19) is perhaps the biggest challenge health-care systems have ever had to face. As part of a series of interviews The ASCO Post is conducting with oncologists, we talked with Charles G. Drake, MD, PhD, about the impact of COVID-19 on his practice and on the conduct...

COVID-19

On the Shoulders of Giants

Before the dawn of the modern antibiotic era and amid the chaos of World War II, future Professor of Radiology and Founding Dean of two American medical colleges, Dr. George T. Harrell,* penned what could now be argued was far too bold a statement. As the opening lines of his nonrandomized study...

COVID-19

Allocating Ventilators in Times of Crisis: A Brave New World

The unprecedented COVID-19 crisis has challenged us, as a society, to evaluate our core values and philosophy. Ventilators, a precious and limited commodity, are now in short supply. Humanity is at a precipice, and we physicians are facing an ethical dilemma, how best to allocate ventilators, and, ...

COVID-19

New Research Highlights Risk of Thromboembolic Complications in Patients With COVID-19

A special report published by Oudkerk et al in the journal Radiology outlined strategies for the prevention, diagnosis, and treatment of thromboembolic complications in patients with COVID-19. Based on recent reports that demonstrated a strong association between elevated D-dimer levels and poor...

COVID-19
Multiple Myeloma

Managing Multiple Myeloma During the COVID-19 Pandemic

In dealing with coronavirus disease 2019 (COVID-19), some oncologists are modifying conventional treatment regimens to limit patients’ visits to infusion centers and providers’ offices. The ASCO Post asked C. Ola Landgren, MD, PhD, Chief of the Myeloma Service at Memorial Sloan Kettering Cancer...

COVID-19
Lung Cancer

AACR 2020: Mortality Rate in Patients With Thoracic Cancers Infected With COVID-19

First results from the TERAVOLT (Thoracic cancERs international coVid 19 cOLlaboraTion) registry for thoracic cancers—presented by Marina C. Garassino, MD, at the American Association for Cancer Research (AACR) Virtual Annual Meeting in the COVID-19 and Cancer Session—indicate a high mortality rate ...

COVID-19

AACR 2020: Outcomes of COVID-19 Infection in Patients With vs Without Cancer: Analysis From 14 Hospitals

In a multi-institutional Chinese study reported at the American Association for Cancer Research (AACR) Virtual Annual Meeting in the COVID-19 and Cancer Session and in Cancer Discovery, Dai et al found that the risk of severe events as a result of COVID-19 infection was higher in patients with...

COVID-19

Prognosis of Patients With Cancer and COVID-19: Outcomes From a Center in New York City

A group of clinicians from New York City sought to determine if patients with cancer and COVID-19 in the United States have a poor prognosis. In an article published as a pre-proof in Annals of Oncology, Miyashita et al analyzed the electronic medical records from the Mount Sinai Health System, and ...

COVID-19

ASCO Shares New Clinical Trial Data, Initiatives, and Path Forward for Post–COVID-19 Cancer Care Delivery System

ASCO (the Society) and its affiliate organization the Association for Clinical Oncology (the Association) recently announced the results of a survey that tracked the initial impact of the COVID-19 pandemic on cancer clinical trials, highlighted a new research initiative to address the data gap on...

covid-19
global cancer care

Jacek Jassem, MD, PhD, on Fighting COVID-19 and Cancer: The View From Poland

Jacek Jassem, MD, PhD, of the Medical University of Gdansk, and an international editor on The ASCO Post Editorial Board, talks about the situation in Poland, how his institution is coping, and the adjustments the staff has made to deliver quality cancer care. Filmed April 17, 2020.

covid-19
global cancer care
skin cancer

Paolo A. Ascierto, MD, on Cancer Treatment During the COVID-19 Pandemic: The View From Southern Italy

Paolo A. Ascierto, MD, of the Istituto Nazionale Tumori in Naples, Italy, talks about minimizing risks for patients with cancer, prioritizing surgery and other treatments for melanoma, and the state of clinical trials. Filmed April 17, 2020.

COVID-19

Hypercoagulability in Critically Ill Patients With COVID-19: Where Do We Stand?

“Life is short, art long, opportunity fleeting, experience treacherous, judgment difficult.” ―Hippocrates The ASCO Post is pleased to present Hematology Expert Review, an ongoing feature that occasionally quizzes readers on issues in hematology. In this installment, Drs. Abutalib and Connors...

COVID-19

AMA Highlights Mental Health Resources for Physicians During COVID-19 Pandemic

Earlier this month, the American Medical Association (AMA) announced resources available to help physicians cope with increased levels of distress and anxiety during the coronavirus disease 2019 (COVID-19) pandemic. These resources build on the AMA’s efforts to ensure physicians and other...

COVID-19

Virtual Appointments Help Patients With Cancer Continue Care During COVID-19 Health Crisis

Texas Oncology recently announced a major expansion of its telemedicine services to allow patients to schedule virtual visits with more than 400 physicians and 150 advanced practice providers throughout the statewide cancer care practice. Through this expanded approach, launched earlier this month, ...

COVID-19

FDA Accelerates Development of Novel Therapies for COVID-19

The U.S. Food and Drug Administration (FDA) has implemented a program to expedite the development of potentially safe and effective life-saving treatments. The program, known as the Coronavirus Treatment Acceleration Program (CTAP), is using every tool at the agency’s disposal to bring new...

COVID-19

Unnecessary Barrier to Blood Donation for British Nationals?

I read with great interest Jo Cavallo’s article “Maintaining Blood Donations During the COVID-19 Pandemic”. My wife and I have been British residents in the United States for over 6 years and are frustrated that we cannot donate blood, especially during this raging global COVID-19 pandemic, when...

covid-19
immunotherapy

Joseph C. Alvarnas, MD, on the Increased Risk of Side Effects for Patients With Cancer and COVID-19

Joseph C. Alvarnas, MD, of the City of Hope National Medical Center, discusses the patients with cancer who are at an increased risk for developing serious complications from COVID-19, including those receiving bone marrow or stem cell transplants and CAR-T cell therapy, and what they can do to protect themselves. Filmed April 17, 2020.

COVID-19

ACS Releases New Guidance to Help Health-Care Facilities Prepare for Resuming Elective Surgery Past COVID-19 Peak

The American College of Surgeons (ACS) has released a new surgical resource document, “Local Resumption of Elective Surgery Guidance,” as a guide for health-care facilities preparing to resume elective surgery once COVID-19 has peaked in their area.  Health-care facilities have been allocating...

Hematologic Malignancies
COVID-19

Potential Protective Effect of Ibrutinib Against Pulmonary Injury in Patients With COVID-19

In a letter published in the journal Blood, Steven P. Treon, MD, PhD, and colleagues reported a potential protective effect against pulmonary injury with the Bruton’s tyrosine kinase (BTK) inhibitor ibrutinib in patients diagnosed with COVID-19 who were receiving the agent for Waldenström’s...

COVID-19

April Is the Cruelest Month

April is the cruelest month, breeding Lilacs out of the dead land, mixing Memory and desire, stirring Dull roots with spring rain. Winter kept us warm, covering Earth in forgetful snow, feeding A little life with dried tubers. —T.S. Eliot, The Burial of the Dead, The Waste Land, 1922 I started...

COVID-19

FDA Authorizes First COVID-19 Test for Patient At-Home Sample Collection

The U.S. Food and Drug Administration (FDA) authorized the first diagnostic test with a home collection option for COVID-19. Specifically, the FDA re-issued the emergency use authorization (EUA) for the Laboratory Corporation of America (LabCorp) COVID-19 RT-PCR Test to permit testing of samples...

COVID-19

Survey Shows COVID-19 Pandemic Is Affecting Patients’ Access to Cancer Care

Patients with cancer and those who have recently completed treatment are finding it challenging to get necessary health care in the midst of the COVID-19 pandemic, and many are experiencing financial stress trying to afford care in an increasingly difficult economic environment. Delays in Care...

COVID-19

Celebrating the Role of Nurses in Meeting the Current Challenges of Cancer Care Delivery

The coronavirus pandemic is being compared to a battlefield, with health-care workers seen as the front-line soldiers in the war against the disease. There is certainly truth to that, insofar as doctors and nurses in many countries now face an unprecedented workload in saving lives, along with the...

global cancer care
covid-19

Giorgio V. Scagliotti, MD, PhD, on the Oncoming Waves of COVID-19: Italy’s Experience

Giorgio V. Scagliotti, MD, PhD, of the University of Turin, talks about the progression of COVID-19 through his community and how, in nursing homes, lack of experience dealing with a pandemic is fueling a third wave of the virus in Italy. Filmed April 15, 2020.

COVID-19

A Segregated-Team Workflow Model During the COVID-19 Pandemic in a Cancer Center

In an article published in Annals of Oncology, members of the National University Cancer Institute of Singapore (NCIS) workflow team described a segregated-team workflow model that allowed continuation of cancer care at the comprehensive cancer center during the COVID-19 outbreak in Singapore....

covid-19
global cancer care

Giorgio V. Scagliotti, MD, PhD, on the Ongoing Battle Against COVID-19: Update From Italy

Giorgio V. Scagliotti, MD, PhD, of the University of Turin, talks about the ways in which coronavirus reshaped Italian hospitals, mistakes made, and lessons learned. Filmed April 15, 2020.

covid-19
global cancer care

Eduardo L. Cazap, MD, PhD, on COVID-19: The View From South America

Eduardo L. Cazap, MD, PhD, of the Sociedad Latinoamericana y del Caribe de Oncología Médica, and an international editor on The ASCO Post Editorial Board, talks about the situation in Argentina treating patients with COVID-19, and the 10-country research effort led by the World Health Organization seeking to fast track research on the coronavirus. Filmed April 7, 2020.

covid-19

Derek Raghavan, MD, PhD, on COVID-19 and Cancer Care: The View From North Carolina

Derek Raghavan, MD, PhD, of the Levine Cancer Institute in Charlotte, and a member of The ASCO Post Editorial Board, discusses the ways in which COVID-19 has affected oncology care in his community, and some practical tips that may help fellow providers. Filmed April 9, 2020.

COVID-19

FDA Encourages Plasma Donation From Patients Who Have Recovered From COVID-19, Collaborates to Produce Supplies for Testing

This week, the U.S. Food and Drug Administration (FDA) issued a statement encouraging patients who have fully recovered from COVID-19 for at least 2 weeks to donate plasma, in order to ramp up supply of convalescent plasma for treatment of infected individuals. The agency also announced that spun...

COVID-19

Hospitals Report Challenges in Responding to the COVID-19 Pandemic

In a report released by the U.S. Department of Health and Human Services (HHS), hospitals reported the most significant challenges they are facing during the COVID-19 pandemic. Survey Methods Brief telephone interviews were conducted from March 23 to March 27, 2020, with one or more administrators ...

COVID-19

Pooled Meta-Analysis of Cancer Prevalence in Patients With COVID-19 Infection

In a meta-analysis reported in JCO Global Oncology, Desai et al found a pooled prevalence of cancer of 2.0% among patients with COVID-19 infection. Key Findings   A literature search identified 11 reports providing data on prevalence of cancer in patients with COVID-19 infection. The overall...

Breast Cancer
COVID-19

Multidisciplinary Recommendations for Breast Cancer Care During the COVID-19 Pandemic

The American Society of Breast Surgeons (ASBrS), the National Accreditation Program for Breast Centers (NAPBC), the National Comprehensive Cancer Network® (NCCN®), the Commission on Cancer (CoC) of the American College of Surgeons, and the American College of Radiology (ACR) have released new joint ...

COVID-19

Practical Approach to Management of Patients With Cancer During the COVID-19 Pandemic: An International Collaborative Group Statement

In an article published in The Oncologist, an international collaborative group outlined issues and potential management approaches for the treatment of patients with cancer during the COVID-19 pandemic. Key issues facing cancer treatment and some of the potential measures for addressing these...

Integrative Oncology
COVID-19

Mind-Body Therapies for Relieving Anxiety and Stress in Patients With Cancer During COVID-19 Pandemic

The rapid spread of the novel coronavirus disease (COVID-19) has dramatically disrupted societal life within a very short time. Patients with cancer in particular can be affected by delays in routine medical care in addition to experiencing heightened anxiety and stress associated with the threat...

Integrative Oncology
COVID-19

Online Mind-Body Resources for Oncologists and Health-Care Workers During the COVID-19 Pandemic

The spread of COVID-19 continues to have a dramatic impact around the world, disrupting social lives and the delivery of oncologic treatments to patients with cancer. Even under “normal” circumstances, health-care professionals, including those in oncology, are prone to occupational stress....

Immunotherapy
COVID-19

Immune Checkpoint Inhibitor Treatment for Patients With Cancer During the COVID-19 Pandemic

In an article published in the journal Immunotherapy, Melissa Bersanelli, MD, of the Medical Oncology Unit, University Hospital of Parma, Italy, discusses controversies regarding the use of immune checkpoint inhibitor therapy in patients with cancer during the COVID-19 pandemic, suggesting that...

COVID-19

ASCO Releases New Guidance on Allocation of Limited Resources in the Oncology Community During COVID-19 Pandemic

ASCO has released a set of recommendations to support the oncology community as health-care institutions across the United States face potentially difficult decisions around the allocation of scarce health-care resources during the COVID-19 pandemic. In some geographic areas, the ongoing crisis is...

COVID-19

ASCO’s New COVID-19 Cancer Registry Aims to Understand Impact on Patients During Pandemic, Inform Future Care

On April 10, ASCO launched the ASCO Survey on COVID-19 in Oncology Registry (ASCO Registry) to help the entire cancer community learn about the pattern of symptoms and severity of COVID-19 among patients with cancer, as well as how COVID-19 infections impact the delivery of cancer care and patient...

COVID-19

NCCN Issues Guidance on Improving COVID-19 Safety for Patients and Health-Care Providers

The National Comprehensive Cancer Network’s® (NCCN®) Best Practices Committee has published a preprint article in JNCCN—Journal of the National Comprehensive Cancer Network detailing their recommendations for keeping patients with cancer, as well as their caregivers and health-care staff, as safe...

COVID-19

Outcomes of COVID-19 Infection in Patients With Cancer in Wuhan, China

In a retrospective cohort study reported in the Annals of Oncology, Li Zhang, MD, of the Department of Oncology, Tongji Hospital, Huazhong University of Science and Technology, Wuhan, China, and colleagues described characteristics and outcomes of COVID-19 infection in 28 patients with cancer from...

covid-19

Nancy E. Davidson, MD, on COVID-19 and Cancer Care: Thoughts From the Seattle Epicenter

Nancy E. Davidson, MD, of the Seattle Cancer Care Alliance, and a member of The ASCO Post Editorial Board, talks about her experiences in one of the communities hardest hit by coronavirus and offers some practical advice on making changes in treatment and research. Recorded April 7, 2020.

hematologic malignancies
covid-19

William A. Wood, MD, MPH, on the New ASH Research Collaborative Data Hub COVID-19 Registry for Hematologic Malignancy

William A. Wood, MD, MPH, of the University of North Carolina at Chapel Hill, and Oversight Group Chair for the new COVID-19 registry, talks about why it was formed, how it can help patients and providers, and how it operates and could evolve in the future. Filmed April 3, 2020.

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